Carlos P. Modenutti - Publications, H-index & Citations

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Carlos P. Modenutti

CONICET

15H-index

56Paper Count

843Citation Count

Published Papers 25

Publication Date

How and Why Does Knowledge-Based Biased Docking Improve Molecular Docking Performance?

ChemMedChem

IF3.4

2026-04-24

PREAI

Juan Manuel Prieto; Jorge Octavio Lannot; Camila Mara Clemente; Carlos Modenutti; Adrian Turjanski; Marcelo A. Martí

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A Cryptic Pocket Allosterically Modulates Oligosaccharide Binding to DC-SIGN

JACS Au

IF8.7

2026-01-20

OAAI

Jonathan Lefèbre; Maurice Besch; Marcelo Daniel Gamarra; Jan-Oliver Kapp-Joswig; Annika Balke; Stevan Aleksić; Henry Flatau; Gregor Suchy; Elena Georgieva; Patrick Scheerer; Bettina G. Keller; Carlos Pablo Modenutti; Christoph Rademacher

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Neuropharmacology of halogenated DMT analogs: psychoplastogenic and antidepressant properties of 5-Br-DMT, a psychedelic derivative with low hallucinogenic potential

Molecular Psychiatry

IF10.1

2025-10-21

OAAI

Pol Puigseslloses; Núria Nadal-Gratacós; Berta Fumàs; Carlos Pablo Modenutti; Eline Pottie; Juan Rodrigo Ortigosa; Albert Pablo-Quesada; Clara Riera-Colomer; Miren Ettcheto; Xavier Berzosa; David Pubill; Christophe Stove; Elena Escubedo; Raúl López-Arnau

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Yerba mate (Ilex paraguariensis) genome provides new insights into convergent evolution of caffeine biosynthesis

ELIFE

IF0

2025-01-08

OAAI

Vignale, Federico A.; Garcia, Andrea Hernandez; Modenutti, Carlos P.; Sosa, Ezequiel J.; Defelipe, Lucas A.; Oliveira, Renato; Nunes, Gisele L.; Acevedo, Raul M.; Burguener, German F.; Rossi, Sebastian M.; Zapata, Pedro D.; Marti, Dardo A.; Sansberro, Pedro; Oliveira, Guilherme; Catania, Emily M.; Smith, Madeline N.; Dubs, Nicole M.; Nair, Satish; Barkman, Todd J.; Turjanski, Adrian G.

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Unveiling crucial amino acids in the carbohydrate recognition domain of a viral protein through a structural bioinformatic approach

GLYCOBIOLOGY

IF3.3

2024-08-30

PREAI

Gamarra, Marcelo D.; Dieterle, Maria Eugenia; Ortigosa, Juan; Lannot, Jorge O.; Capurro, Juan I. Blanco; Di Paola, Matias; Radusky, Leandro; Duette, Gabriel; Piuri, Mariana; Modenutti, Carlos P.

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Rescue of secretion of rare-disease-associated misfolded mutant glycoproteins in UGGT1 knock-out mammalian cells

TRAFFIC

IF2.5

2024-01-14

OAAI

Tax, Gabor; Guay, Kevin P.; Pantalone, Ludovica; Ceci, Martina; Solda, Tatiana; Hitchman, Charlie J.; Hill, Johan C.; Vasiljevic, Snezana; Lia, Andrea; Modenutti, Carlos P.; Straatman, Kees R.; Santino, Angelo; Molinari, Maurizio; Zitzmann, Nicole; Hebert, Daniel N.; Roversi, Pietro; Trerotola, Marco

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First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival

JCI INSIGHT

IF6.1

2023-04-25

OAAI

Guijarro, Maria V.; Kellish, Patrick C.; Dib, Peter E.; Paciaroni, Nicholas G.; Nawab, Akbar; Andring, Jacob; Kulemina, Lidia; Borrero, Nicholas V.; Modenutti, Carlos; Feely, Michael; Nasri, Elham; Seifert, Robert P.; Luo, Xiaoping; Bennett, Richard L.; Shabashvili, Daniil; Licht, Jonathan D.; McKenna, Robert; Roitberg, Adrian; Huigens, Robert W.; Kaye, Frederic J.; Zajac-Kaye, Maria

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Discovery of a first-in-class multifunctional TYMS non-classical antifolate inhibitors with potent in vivo activity that prolongs survival

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Dib, Peter Elias; Guijarro, Maria; Kellish, Patrick; Paciaroni, Nick; Nawab, Akbar; Andring, Jacob; Kulemina, Lidia; Leas, Derek; Borrero, Nick; Modenutti, Carlos; Bennett, Richard; Licht, Jonathan; McKenna, Robert; Roitberg, Adrian; Kaye, Frederic; Zajac-Kaye, Maria

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Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin

ACS CHEMICAL BIOLOGY

IF3.8

2022-09-26

OAAI

Zhang, Hengxi; Modenutti, Carlos; Nekkanti, Yelha Phani Kumar; Denis, Maxime; Bermejo, Iris A.; Lefebre, Jonathan; Che, Kateryna; Kim, Dongyoon; Kagelmacher, Marten; Kurzbach, Dennis; Nazare, Marc; Rademacher, Christoph

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MotSASi: Functional short linear motifs (SLiMs) prediction based on genomic single nucleotide variants and structural data

BIOCHIMIE

IF3

2022-06-01

OAAI

Martin, Mariano; Brunello, Franco G.; Modenutti, Carlos P.; Nicola, Juan P.; Marti, Marcelo A.

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A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-11-08

OAAI

Wawrzinek, Robert; Wamhoff, Eike-Christian; Lefebre, Jonathan; Rentzsch, Mareike; Bachem, Gunnar; Domeniconi, Gary; Schulze, Jessica; Fuchsberger, Felix F.; Zhang, Hengxi; Modenutti, Carlos; Schnirch, Lennart; Marti, Marcelo A.; Schwardt, Oliver; Braeutigam, Maria; Guberman, Monica; Hauck, Dirk; Seeberger, Peter H.; Seitz, Oliver; Titz, Alexander; Ernst, Beat; Rademacher, Christoph

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A Novel SLC5A5 Variant Reveals the Crucial Role of Kinesin Light Chain 2 in Thyroid Hormonogenesis

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IF5.1

2021-04-29

OAAI

Martin, Mariano; Pablo Modenutti, Carlos; Gil Rosas, Mauco Lucas; Peyret, Victoria; Celeste Geysels, Romina; Bernal Barquero, Carlos Eduardo; Sobrero, Gabriela; Munoz, Liliana; Signorino, Malvina; Testa, Graciela; Beatriz Miras, Mirta; Maria Masini-Repiso, Ana; Beatriz Calcaterra, Nora; Coux, Gabriela; Carrasco, Nancy; Adrian Marti, Marcelo; Pablo Nicola, Juan

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Longitudinal characterization of HIV-1 pol-gene in treatment-naive men-who-have-sex-with-men from acute to chronic infection stages

HELIYON

IF3.6

2020-12-01

OAAI

Cevallos, Cintia; Culasso, Andres C. A.; Modenutti, Carlos; Gun, Ana; Sued, Omar; Avila, Maria M.; Flichman, Diego; Delpino, M. Victoria; Quarleri, Jorge

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The Structural Biology of Galectin-Ligand Recognition: Current Advances in Modeling Tools, Protein Engineering, and Inhibitor Design

FRONTIERS IN CHEMISTRY

IF4.2

2019-12-03

OAAI

Modenutti, Carlos P.; Blanco Capurro, Juan, I; Di Lella, Santiago; Marti, Marcelo A.

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Cosolvent-Based Protein Pharmacophore for Ligand Enrichment in Virtual Screening

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2019-08-02

OAAI

Pablo Arcon, Juan; Defelipe, Lucas A.; Lopez, Elias D.; Burastero, Osvaldo; Modenutti, Carlos P.; Barril, Xavier; Marti, Marcelo A.; Turjanski, Adrian G.

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Exploring lectin-like activity of the S-layer protein of Lactobacillus acidophilus ATCC 4356

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

IF4.3

2019-05-03

OAAI

Fina Martin, Joaquina; Mercedes Palomino, Maria; Cutine, Anabella M.; Modenutti, Carlos P.; Fernandez Do Porto, Dario A.; Allievi, Mariana C.; Zanini, Sofia H.; Marino, Karina V.; Barquero, Andrea A.; Ruzal, Sandra M.

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Solvents to Fragments to Drugs: MD Applications in Drug Design

MOLECULES

IF4.6

2018-12-11

OAAI

Defelipe, Lucas A.; Pablo Arcon, Juan; Modenutti, Carlos P.; Marti, Marcelo A.; Turjanski, Adrian G.; Barril, Xavier

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A Carboxy-Terminal Monoleucine-Based Motif Participates in the Basolateral Targeting of the Na+/I- Symporter

ENDOCRINOLOGY

IF3.3

2018-11-28

OAAI

Martin, Mariano; Pablo Modenutti, Carlos; Peyret, Victoria; Geysels, Romina Celeste; Darrouzet, Elisabeth; Pourcher, Thierry; Maria Masini-Repiso, Ana; Adrian Marti, Marcelo; Carrasco, Nancy; Pablo Nicola, Juan

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An efficient use of X-ray information, homology modeling, molecular dynamics and knowledge-based docking techniques to predict protein-monosaccharide complexes

GLYCOBIOLOGY

IF3.3

2018-11-08

OAAI

Blanco Capurro, Juan I.; Di Paola, Matias; Daniel Gamarra, Marcelo; Marti, Marcelo A.; Modenutti, Carlos P.

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Molecular Dynamics in Mixed Solvents Reveals Protein-Ligand Interactions, Improves Docking and Allows Accurate Binding Free Energy Predictions (vol 57, pg 846, 2017)

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2018-06-13

OAAI

Arcon, Juan Pablo; Defelipe, Lucas A.; Modenutti, Carlos P.; Lopez, Elias D.; Garcia, Daniel Alvarez; Barril, Xavier; Turjanski, Adrian G.; Marti, Marcelo A.

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Research Directions