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А. А. Гилеп

national academy of sciences of belarus (nasb)

25H-index
173Paper Count
2.2KCitation Count
Published Papers 31
Publication Date
The Activation of Cytochrome P450 2C9 Is Facilitated by the Coenzyme Forms of Vitamin B2
err2025-09-10
err0
errOAAI
errPolina I. Koroleva; Alexey V. Kuzikov; Andrei A. Gilep; Sergey V. Ivanov; Alexander I. Archakov; Victoria V. Shumyantseva
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Role Assessment of Water-Soluble Pharmaceutical Form of Phosphatidylcholine on the Catalytic Activity of Cytochrome P450 2C9 and 2D6
err2024-12-24
err1
errOAAI
errKoroleva, Polina I.; Bulko, Tatiana V.; Kuzikov, Alexey V.; Gilep, Andrei A.; Romashova, Yulia A.; Tichonova, Elena G.; Kostrukova, Lyubov V.; Archakov, Alexander I.; Shumyantseva, Victoria V.
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Electrochemical Assessment of CYP3A4 Catalytic Activity in Bactosomes
err2024-07-12
err0
PREAI
errKoroleva, Polina I.; Kuzikov, Alexey V.; Gilep, Andrei A.; Bulko, Tatiana V.; Shumyantseva, Victoria V.
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Bielectrode Strategy for Determination of CYP2E1 Catalytic Activity: Electrodes with Bactosomes and Voltammetric Determination of 6-Hydroxychlorzoxazone
err2024-01-11
err3
errOAAI
errKuzikov, Alexey V.; Masamrekh, Rami A.; Filippova, Tatiana A.; Tumilovich, Anastasiya M.; Strushkevich, Natallia V.; Gilep, Andrei A.; Khudoklinova, Yulia Yu.; Shumyantseva, Victoria V.
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Molecular Cloning, Heterologous Expression, Purification, and Evaluation of Protein-Ligand Interactions of CYP51 of Candida krusei Azole-Resistant Fungal Strain
err2023-10-24
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errOAAI
errTsybruk, Tatsiana V.; Kaluzhskiy, Leonid A.; Mezentsev, Yuri V.; Makarieva, Tatyana N.; Tabakmaher, Kseniya M.; Ivanchina, Natalia V.; Dmitrenok, Pavel S.; Baranovsky, Alexander V.; Gilep, Andrei A.; Ivanov, Alexis S.
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Approaches for increasing the electrocatalitic efficiency of cytochrome P450 3A4
err2023-02-01
err5
PREAI
errShumyantseva, Victoria V.; Koroleva, Polina I.; Bulko, Tatiana, V; Shkel, Tatyana, V; Gilep, Andrei A.; Veselovsky, Alexander V.
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Structural insights into 3Fe-4S ferredoxins diversity in M. tuberculosis highlighted by a first redox complex with P450
err2023-01-09
err5
errOAAI
errGilep, Andrei; Varaksa, Tatsiana; Bukhdruker, Sergey; Kavaleuski, Anton; Ryzhykau, Yury; Smolskaya, Sviatlana; Sushko, Tatsiana; Tsumoto, Kouhei; Grabovec, Irina; Kapranov, Ivan; Okhrimenko, Ivan; Marin, Egor; Shevtsov, Mikhail; Mishin, Alexey; Kovalev, Kirill; Kuklin, Alexander; Gordeliy, Valentin; Kaluzhskiy, Leonid; Gnedenko, Oksana; Yablokov, Evgeniy; Ivanov, Alexis; Borshchevskiy, Valentin; Strushkevich, Natallia
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Combining of synthetic VHH and immune scFv libraries for pregnancy-associated glycoproteins ELISA development
err2022-06-20
err3
PREAI
errDormeshkin, Dmitri; Shapira, Michail; Karputs, Alena; Kavaleuski, Anton; Kuzminski, Ivan; Stepanova, Elena; Gilep, Andrei
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PharmVar GeneFocus: CYP3A5
err2022-03-29
err31
errOAAI
errRodriguez-Antona, Cristina; Savieo, Jessica L.; Lauschke, Volker M.; Sangkuhl, Katrin; Drogemoller, Britt, I; Wang, Danxin; Schaik, Ron N. H.; Gilep, Andrei A.; Peter, Arul P.; Boone, Erin C.; Ramey, Bronwyn E.; Klein, Teri E.; Whirl-Carrillo, Michelle; Pratt, Victoria M.; Gaedigk, Andrea
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Human Lanosterol 14-Alpha Demethylase (CYP51A1) Is a Putative Target for Natural Flavonoid Luteolin 7,3′-Disulfate
err2021-04-13
err15
errOAAI
errKaluzhskiy, Leonid; Ershov, Pavel; Yablokov, Evgeniy; Shkel, Tatsiana; Grabovec, Irina; Mezentsev, Yuri; Gnedenko, Oksana; Usanov, Sergey; Shabunya, Polina; Fatykhava, Sviatlana; Popov, Alexander; Artyukov, Aleksandr; Styshova, Olga; Gilep, Andrei; Strushkevich, Natallia; Ivanov, Alexis
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A new insight into subinteractomes of functional antagonists: Thromboxane (CYP5A1) and prostacyclin (CYP8A1) synthases
err2021-02-19
err8
PREAI
errErshov, Pavel V.; Yablokov, Evgeniy; Zgoda, Victor; Mezentsev, Yuri; Gnedenko, Oksana; Kaluzhskiy, Leonid; Svirid, Andrey; Gilep, Andrei; Usanov, Sergey A.; Ivanov, Alexis
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All-electrochemical nanocomposite two-electrode setup for quantification of drugs and study of their electrocatalytical conversion by cytochromes P450
err2020-03-01
err29
PREAI
errShumyantseva, Victoria V.; Bulko, Tatiana V.; Kuzikov, Alexey V.; Masamrekh, Rami A.; Konyakhina, Apollinariya Yu; Romanenko, Iuliia; Max, Johannes B.; Koehler, Moritz; Gilep, Andrei A.; Usanov, Sergey A.; Pergushov, Dmitry V.; Schacher, Felix H.; Sigolaeva, Larisa V.
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Electrochemical oxidation of estrogens as a method for CYP19A1 (aromatase) electrocatalytic activity determination
err2020-02-01
err14
PREAI
errKuzikov, Alexey V.; Masamrekh, Rami A.; Filippova, Tatiana A.; Haurychenka, Yaraslau I.; Gilep, Andrei A.; Shkel, Tatsiana V.; Strushkevich, Natallia V.; Usanov, Sergey A.; Shumyantseva, Victoria V.
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Interaction of Isatin with Cytochrome P450 Isoenzymes: Investigation by Means of Spectral and Electrochemical Methods The role of Isatin in Cytochromes P450 Ligand-Protein Binding Events
err2020-01-08
err0
PREAI
errKuzikov, Alexey; Masamrekh, Rami; Ershov, Pavel; Mezentsev, Yuri; Ivanov, Alexis; Gilep, Andrei; Usanov, Sergey; Shumyantseva, Victoria
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A large-scale comparative analysis of affinity, thermodynamics and functional characteristics of interactions of twelve cytochrome P450 isoforms and their redox partners
err2019-07-01
err22
PREAI
errYablokov, Evgeniy O.; Sushko, Tatsiana A.; Ershov, Pavel, V; Florinskaya, Anna, V; Gnedenko, Oksana, V; Shkel, Tatsiana, V; Grabovec, Irina P.; Strushkevich, Natallia, V; Kaluzhskiy, Leonid A.; Usanov, Sergey A.; Gilep, Andrei A.; Ivanov, Alexis S.
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Affinity Isolation and Mass Spectrometry Identification of Prostacyclin Synthase (PTGIS) Subinteractome
err2019-06-20
err9
errOAAI
errErshov, Pavel, V; Mezentsev, Yuri, V; Kopylov, Arthur T.; Yablokov, Evgeniy O.; Svirid, Andrey, V; Lushchyk, Aliaksandr Ya; Kaluzhskiy, Leonid A.; Gilep, Andrei A.; Usanov, Sergey A.; Medvedev, Alexey E.; Ivanov, Alexis S.
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Assessment of electrocatalytic hydroxylase activity of cytochrome P450 3A4 (CYP3A4) by means of derivatization of 6β-hydroxycortisol by sulfuric acid for fluorimetric assay
errTALANTA
IF6.1
err2019-05-01
err9
PREAI
errKuzikov, Alexey; Masamrekh, Rami; Shkel, Tatsiana; Strushkevich, Natallia; Gilep, Andrei; Usanov, Sergey; Archakov, Alexander; Shumyantseva, Victoria
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Interaction of 17α-hydroxylase, 17(20)-lyase (CYP17A1) inhibitors - abiraterone and galeterone - with human sterol 14α-demethylase (CYP51A1)
err2018-09-01
err18
PREAI
errMasamrekh, Rami; Kuzikov, Alexey; Veselovsky, Alexander; Toropygin, Iliya; Shkel, Tatsiana; Strushkevich, Natalia; Gilep, Andrei; Usanov, Sergey; Archakov, Alexander; Shumyantseva, Victoria
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Thermodynamics of interactions between mammalian cytochromes P450 and b5
err2017-04-01
err22
PREAI
errYablokov, Evgeny; Florinskaya, Anna; Medvedev, Alexei; Sergeev, Gennady; Strushkevich, Natallia; Luschik, Alexander; Shkel, Tatsiana; Haidukevich, Irina; Gilep, Andrei; Usanov, Sergey; Ivanov, Alexis
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