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K

Keng‐Chang Tsai

ministry of health and welfare

29H-index
132Paper Count
2.7KCitation Count
Published Papers 59
Publication Date
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Isorhoifolin regulates S1PR3-CK2-GSK3β axis and promotes neurite regrowth and functional recovery after traumatic brain injury
errPhytomedicine
IF8.3
err2026-08-04
err0
errOAAI
errYi Wang; Wen-Ling Liao; Chen Wang; Yun-Chen Li; Ting-Hsuan Lu; Chia-Hung Yen; Teng-Kuang Yeh; Hsing-Pang Hsieh; Cheng-Ta Hsieh; Keng-Chang Tsai; Hui-Chun Cheng; Linyi Chen
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NeuproGemp; a polyphenol-rich botanical formula; ameliorates Alzheimer’s-like pathology in APP/PS1 mice via inhibition of human glutaminyl cyclase
errFrontiers in Pharmacology
IF4.8
err2025-10-21
err0
errOAAI
errTien-Sheng Tseng; Chia-Ching Liaw; Young-Ji Shiao; Ya-I Huang; Yu-Hsiu Cheng; Wang-Chuan Chen; Keng-Chang Tsai
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Impact of humanization scaffold design on the functional activity of FGFR2-targeting chicken scFvs
errJournal of Biotechnology
IF3.9
err2025-10-17
err0
PREAI
errShyi-Chun Yii; Tsai-Yu Lin; Fu-Ling Chang; Fu-Shan Jaw; Keng-Chang Tsai; Yun-Shih Lin; Yu-Ching Lee
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Synthesis of Acinetobacter baumannii Lipid A(s) and derivatives and their structure-immunostimulatory activity relationships
errCommunications Chemistry
IF6.2
err2025-08-06
err0
errOAAI
errXin-Ru Li; Janet Jia-Yin Tan; Chiao-Wen Chen; Jhen-Yan Huang; Hsien-Ya Lin; Boon Hee Goh; Keng-Chang Tsai; Chun-Hung Lin; Kwok-Kong Tony Mong
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Time-dependent inactivation of human cytochrome P450 2A6 variants and 2A13 by imperatorin: natural coumarins and imperatorin oxidation
errBiochemical Pharmacology
IF5.6
err2025-07-12
err0
PREAI
errYune-Fang Ueng; Jia-Shan Chih; Wen-Tai Li; An-Chi Chen; Keng-Chang Tsai; Chia-Ching Liaw; Kuan-Wen Chen; Pei-Syuan Chen; Chu Lin Hsiao
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Application of bioactive molecular networking to identify corneal-cytoprotective compounds from Dialium cochinchinense Pierre. leaves
errcurrent opinion in plant biology
IF4.5
err2025-06-01
err0
errOAAI
errThi Tuyet Nhung Nguyen; Yu-Chi Lin; Le-Anh-Tuan Nguyen; Chih-Hua Chao; Thanh-Hoa Vo; Su-Jung Hsu; Keng-Chang Tsai; Ching-Kuo Lee; Jing-Jy Cheng
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Broad-spectrum antiviral activity of Ganoderma microsporum immunomodulatory protein: Targeting glycoprotein gB to inhibit EBV and HSV-1 infections via viral fusion blockage
errINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
IF8.5
err2025-05-01
err0
PREAI
errVo, Di Ngoc Kha; Ho, Ha Phan Thanh; Wu, Li-Syuan; Chen, Yi-Yun; Trinh, Hang Thi Viet; Lin, Tung-Yi; Lim, Yat-Yuen; Tsai, Keng-Chang; Tsai, Ming-Han
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Discovery and biological evaluation of potent 2-trifluoromethyl acrylamide warhead-containing inhibitors of protein disulfide isomerase
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-02-01
err0
PREAI
errChu, Jung-Chun; Tsai, Keng-Chang; Wang, Ting-Yu; Chen, Tzu-Yin; Tsai, Ju-Ying; Lee, Tien; Lin, Mei-Hsiang; Hsieh, Yves S. Y.; Wu, Chin-Chung; Huang, Wei-Jan
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Discovery of a novel C2-functionalized chromen-4-one scaffold for the development of p38α MAPK signaling inhibitors to mitigate neutrophilic inflammatory responses
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2025-02-01
err0
PREAI
errChang, Yi-Han; Lee, Yi-Chen; Chen, Shun-Hua; Fang, Shu-Yen; Cheng, Tzu-Peng; Chi, Ching-Ho; Tsai, Keng-Chang; Chen, Po-Jen; Hung, Hsin-Yi
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The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas (vol 154, 108068, 2025)
errBIOORGANIC CHEMISTRY
IF4.7
err2025-01-01
err0
PREAI
errLai, Hsuan-Yu; Yu, Ko-Hua; Tsai, Keng-Chang; Lee, Chao-Chang; Wang, Han-Yu; Hsieh, Yi-Ping; Chiang, Kuan-Yi; Kuo, Pao-Lin; Huang, Tze-Ta; Hung, Hsin-Yi
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errSave
DCBCI2203, a novel protein degrader targeting KRAS G12D/V
errEUROPEAN JOURNAL OF CANCER
IF7.1
err2024-10-01
err0
PREAI
errYang, Y. N.; Yen, S. C.; Liao, C. N.; Lee, Y. S.; Tsai, K. C.
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errSave
Discovery of oral chemotherapeutic reversal agents for treating multidrug resistance cancer
errEUROPEAN JOURNAL OF PHARMACOLOGY
IF4.7
err2024-08-01
err0
PREAI
errYu, Ko-Hua; Wu, I-Ting; Yu, Cheng-Ping; Wang, Wei-Chun; Chi, Ching-Ho; Tsai, Keng-Chang; Chou, Chen-Hsi; Hung, Chin-Chuan; Hung, Hsin-Yi
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Xin-yi-san contains potent human CYP1A2 inhibitors and its combined use with theophylline in treatment increases adverse risks in patients
errPHYTOMEDICINE
IF8.3
err2024-07-01
err0
PREAI
errKao, Li-Ting; Chen, An-Chi; Wang, Hong-Jaan; Wen, Yuan-Liang; Lu, Chung-Kuang; Liaw, Chia-Ching; Tsai, Keng-Chang; Ueng, Yune-Fang
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Structure-Guided Discovery of PD-1/PD-L1 Interaction Inhibitors: Peptide Design, Screening, and Optimization via Computation-Aided Phage Display Engineering
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2024-02-15
err1
PREAI
errTseng, Tien-Sheng; Lee, Chao-Chang; Chen, Po-Juei; Lin, Chiu-Yuen; Chen, Wang-Chuan; Lee, Yu-Ching; Lin, Jiun-Han; Chen, Kaun-Wen; Tsai, Keng-Chang
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errSave
Ser38-His93-Asn91 triad confers resistance of JFH1 HCV NS5A-Y93H variant to NS5A inhibitors
errFEBS JOURNAL
IF4.2
err2024-01-03
err0
PREAI
errLee, Wei-Ping; Tsai, Keng-Chang; Liao, Shi-Xian; Huang, Yi-Hsiang; Hou, Ming-Chih; Lan, Keng-Hsin
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Ser235 phosphorylation of hepatitis C virus NS5A is required for NS5A dimerization and drug resistance
errLIFE SCIENCES
IF5.1
err2024-01-01
err0
PREAI
errLee, Wei-Ping; Tsai, Keng-Chang; Liao, Shi-Xian; Huang, Yi-Hsiang; Hou, Ming-Chih; Lan, Keng-Hsin
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Novel (-)-arctigenin derivatives inhibit signal transducer and activator of transcription 3 phosphorylation and P-glycoprotein function resensitizing multidrug resistant cancer cells in vitro and in vivo
errEUROPEAN JOURNAL OF PHARMACOLOGY
IF4.7
err2023-12-01
err3
PREAI
errYu, Ko-Hua; Kuo, Chan-Yen; Wu, I-Ting; Chi, Ching-Ho; Tsai, Keng-Chang; Kuo, Ping-Chung; Zeng, Jing-Wen; Hung, Chin-Chuan; Hung, Hsin-Yi
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Design and synthesis of pyrazole derivatives against neutrophilic inflammation
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-12-01
err0
PREAI
errYu, Ko-Hua; Tien, Kai-wen; Wang, Wei-Chun; Chi, Ching-Ho; Tsai, Keng-Chang; Chou, Chen-Hsi; Hwang, Tsong-Long; Hung, Hsin-Yi
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errSave
Effectiveness of anti-erythropoietin producing Hepatocellular receptor Type-A2 antibody in pancreatic cancer treatment
errHELIYON
IF3.6
err2023-11-01
err1
errOAAI
errChang, Fu-Ling; Tsai, Keng-Chang; Lin, Tsai-Yu; Chiang, Chen-Wei; Pan, Shiow-Lin; Lee, Yu-Ching
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errSave
Development of anti-aflatoxin B1 nanobodies from a novel mutagenesis-derived synthetic library for traditional Chinese medicine and foods safety testing
errJOURNAL OF BIOLOGICAL ENGINEERING
IF6.5
err2023-04-24
err10
errOAAI
errLee, Yu-Ching; Lai, Gar-Hwa; Lin, Tsai-Yu; Tseng, Tien-Sheng; Tsai, Tsung-Hsun; Chen, Wang-Chuan; Lee, Cheng-Chung; Tsai, Keng-Chang
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Research Directions

No research directions
Co-authors
Cooperation Journals
C
Chi‐Huey Wong
H-index: 126 · Papers: 1.1K
B
Binghe Wang
H-index: 83 · Papers: 723
Y
Yun Yen
H-index: 74 · Papers: 689
Y
Yi‐Ling Lin
H-index: 69 · Papers: 360
Y
Yi‐Hsiang Huang
H-index: 63 · Papers: 823
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