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Stephen L. Bearne

Dalhousie University

25H-index
116Paper Count
1.7KCitation Count
Published Papers 36
Publication Date
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Inhibition of Mandelate Racemase by Boron-Based Inhibitors: Different Binding Modes for Benzoxaboroles Versus Boronic Acids
errBiochemistry
IF3
err2025-12-01
err0
PREAI
errHayden, Joshua A.; Jabin, Anika; Kuehm, Oliver P.; Moncrief, Julia G.; St Maurice, Martin; Bearne, Stephen L.
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Advanced polyelectrolyte complexes for ultrafast hemostasis and blood superabsorption
errActa Biomaterialia
IF9.6
err2025-11-13
err0
errOAAI
errSajjad Fanaee; Alireza Zabihihesari; Tianqin Ning; William Austin; Max Wolverton; Brendan M. Leung; Stephen L. Bearne; Jianyu Li; Mark Joseph Filiaggi; Vahid Adibnia
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An Active-Site Bronsted Acid-Base Catalyst Destabilizes Mandelate Racemase and Related Subgroup Enzymes: Implications for Catalysis
errBIOCHEMISTRY
IF3
err2025-01-21
err0
PREAI
errKumar, Himank; Kuehm, Oliver P.; Aboushawareb, Sarah A. E.; Rafiei, Atieh; Easton, Nicole M.; Bearne, Stephen L.
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Biochemical communication between filament-forming enzymes Potential Regulatory Roles of Metabolites in Enzyme Co-assemblies with CTP Synthase
errBIOESSAYS
IF2.7
err2024-07-08
err2
errOAAI
errBearne, Stephen L.
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errSave
Interrogating L-fuconate dehydratase with tartronate and 3-hydroxypyruvate reveals subtle differences within the mandelate racemase-subgroup of the enolase superfamily
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2024-04-01
err1
PREAI
errMcGary, Laura C.; Fetter, Christopher M.; Gu, Minglu; Hamilton, Meghan C.; Kumar, Himank; Kuehm, Oliver P.; Douglas, Colin D.; Bearne, Stephen L.
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Capturing the free energy of transition state stabilization: insights from the inhibition of mandelate racemase
errPHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
IF4.7
err2023-01-11
err6
errOAAI
errBearne, Stephen L. L.
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Reactivity and mechanism in chemical and synthetic biology
errPHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
IF4.7
err2023-01-11
err0
errOAAI
errRichards, Nigel G. J.; Bearne, Stephen L.; Goto, Yuki; Parker, Emily J.
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Effects of the 5′-Triphosphate Metabolites of Ribavirin, Sofosbuvir, Vidarabine, and Molnupiravir on CTP Synthase Catalysis and Filament Formation: Implications for Repurposing Antiviral Agents against SARS-CoV-2
errCHEMMEDCHEM
IF3.4
err2022-10-26
err0
errOAAI
errGillis, Thomas D.; Bearne, Stephen L.
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Altering the binding determinant on the interdigitating loop of mandelate racemase shifts specificity towards that of D-tartrate dehydratase
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2022-03-01
err3
PREAI
errNagar, Mitesh; Hayden, Joshua A.; Sagey, Einat; Worthen, George; Park, Mika; Sharma, Amar Nath; Fetter, Christopher M.; Kuehm, Oliver P.; Bearne, Stephen L.
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Through the Looking Glass: Chiral Recognition of Substrates and Products at the Active Sites of Racemases and Epimerases
errCHEMISTRY-A EUROPEAN JOURNAL
IF3.7
err2020-07-21
err15
PREAI
errBearne, Stephen L.
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errSave
Heat Shock Proteins in the Hot Mitochondrion: Identity and Putative Roles
errBIOESSAYS
IF2.7
err2019-08-05
err18
PREAI
errNasr, Mohamed A.; Dovbeshko, Galina, I; Bearne, Stephen L.; El-Badri, Nagwa; Matta, Cherif F.
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Altering the Y137-K164-K166 triad of mandelate racemase and its effect on the observed pKa of the Bronsted base catalysts
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2019-05-01
err9
PREAI
errFetter, Christopher M.; Morrison, Zachary A.; Nagar, Mitesh; Douglas, Colin D.; Bearne, Stephen L.
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errSave
Anfractuous assemblies of IMP dehydrogenase and CTP synthase: new twists on regulation?
errFEBS JOURNAL
IF4.2
err2018-10-04
err2
errOAAI
errMcCluskey, Gregory D.; Bearne, Stephen L.
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Changes in quaternary structure cause a kinetic asymmetry of glutamate racemase-catalyzed homocysteic acid racemization
errFEBS LETTERS
IF3
err2018-09-24
err4
errOAAI
errMackie, Joanna; Kumar, Himank; Bearne, Stephen L.
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Measuring benzohydroxamate complexation with Mg2+, Mn2+, Co2+, and Ni2+ using isothermal titration calorimetry
errJOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
IF3.1
err2016-02-11
err14
PREAI
errHarty, Matthew; Bearne, Stephen L.
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Rational design and synthesis of substrate-product analogue inhibitors of α-methylacyl-coenzyme A racemase from Mycobacterium tuberculosis
errCHEMICAL COMMUNICATIONS
IF4.2
err2016-01-01
err15
PREAI
errPal, Mohan; Khanal, Mandar; Marko, Ryan; Thirumalairajan, Srinath; Bearne, Stephen L.
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Oxidative stress response in the opportunistic oral pathogen Fusobacterium nucleatum
errPROTEOMICS
IF3.9
err2011-05-11
err33
PREAI
errSteeves, Craig H.; Potrykus, Joanna; Barnett, David A.; Bearne, Stephen L.
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Interrogation of the active site of OMP decarboxylase from Escherichia coli with a substrate analogue bearing an anionic group at C6
errCHEMICAL COMMUNICATIONS
IF4.2
err2010-01-01
err11
PREAI
errThirumalairajan, Srinath; Mahaney, Brandi; Bearne, Stephen L.
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Kinetic characterization and quaternary structure of glutamate racemase from the periodontal anaerobe Fusobacterium nucleatum (vol 491, pg 16, 2009)
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2010-01-01
err0
PREAI
errPotrykus, Joanna; Flemming, Janette; Bearne, Stephen L.
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errSave
Kinetic characterization and quaternary structure of glutamate racemase from the periodontal anaerobe Fusobacterium nucleatum
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2009-11-01
err14
PREAI
errPotrykus, Joanna; Flemming, Janette; Bearne, Stephen L.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
R
Richard Wolfenden
H-index: 62 · Papers: 250
C
Chérif F. Matta
H-index: 45 · Papers: 247
J
Jianyu Li
H-index: 42 · Papers: 311
Y
Yuki Goto
H-index: 39 · Papers: 208
N
Nigel G. J. Richards
H-index: 36 · Papers: 198
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