Kurt A. Schalper - Publications, H-index & Citations

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Kurt A. Schalper

pathology

70H-index

605Paper Count

2.4WCitation Count

Published Papers 89

Publication Date

NSCLC brain metastases exhibit reduced HLA-I antigen presentation machinery and immune evasion independent of IFNγ signaling defects

Molecular Cancer

IF33.9

2026-05-28

OAAI

Noelia Vilariño; Miguel López de Rodas; Maria Villalba-Esparza; Barani Kumar Rajendran; Boyu Huang; Sara Hijazo-Pechero; Adrien Costantini; Kishu Ranjan; Javier Ramos-Paradas; Benjamin Y. Lu; Ernest Nadal; Sarah B. Goldberg; Don X. Nguyen; Kurt A. Schalper

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Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers

Nature Communications

IF15.7

2026-05-21

OAAI

Nabamita Boruah; David Hoyos; Renyta Moses; Ryan Hausler; Heena Desai; Anh N. Le; Madeline Good; Gregory Kelly; Ashvathi Raghavakaimal; Maliha Tayeb; Mohana Narasimhamurthy; Abigail Doucette; Peter Gabriel; Michael J. Feldman; Jinae Park; Miguel Lopez de Rodas; Kurt A. Schalper; Shari B. Goldfarb; Anupma Nayak; Arnold J. Levine; Benjamin D. Greenbaum; Kara N. Maxwell

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MET (c-Met) protein overexpression is an emerging protein biomarker in non-small cell lung cancer

npj Precision Oncology

IF8

2025-11-20

OAAI

Ming-Sound Tsao; Lynette Sholl; Michelle Shiller; Peter Illei; Ignacio I. Wistuba; Mary Beth Beasley; Kurt A. Schalper; Archana Simmons; Peter Ansell; Sue Beruti; Mari Mino-Kenudson

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Spatial signatures for predicting immunotherapy outcomes using multi-omics in non-small cell lung cancer

Nature Genetics

IF29

2025-10-10

OAAI

Thazin N. Aung; James Monkman; Jonathan Warrell; Ioannis Vathiotis; Katherine M. Bates; Niki Gavrielatou; Ioannis P. Trontzas; Chin Wee Tan; Aileen I. Fernandez; Myrto Moutafi; Ken O’ Byrne; Kurt A. Schalper; Konstantinos Syrigos; Roy S. Herbst; Arutha Kulasinghe; David L. Rimm

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Molecular Tumor Boards: A consensus statement from the International Association for the Study of Lung Cancer

Journal of Thoracic Oncology

IF20.8

2025-07-07

PREAI

Mihaela Aldea; Julia K. Rotow; Maria Arcila; Matthew Hatton; Lynette Sholl; Christian Rolfo; Marco Tagliamento; Teodora Radonic; Kurt A. Schalper; Vivek Subbiah; Umberto Malapelle; Anja C. Roden; Rami Manochakian; Ming-Sound Tsao; Helena Linardou; Rina Hui; Silvia Novello; Alastair Greystoke; Anjali Saqi; Sylvie Lantuejoul; David M. Hwang; Kelly Nevins; Murry Wynes; Saiama Waqar; Yuchen Han; Yasushi Yatabe; Wei-Chin Chang; Takuo Hayashi; Tae-Jung Kim; Paul Hofman; Fabio Tavora; Fred R. Hirsch; Valeria Denninghoff; Natasha B. Leighl; Alexander Drilon; Wendy A. Cooper; Sanja Dacic; Pranshu Mohindra; Nick Pavlakis; Fernando Lopez-Rios

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IL-4 mediated TAP2 downregulation is a dominant and reversible mechanism of immune evasion and immunotherapy resistance in non-small cell lung cancer

MOLECULAR CANCER

IF33.9

2025-03-17

OAAI

Ranjan, Kishu; Rajendran, Barani Kumar; Deen, Imad Ud; Costantini, Adrien; de Rodas, Miguel Lopez; Desai, Shruti S.; Scallo, Frankie; Gianino, Nicole; Ferrone, Soldano; Schalper, Kurt A.

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A Phase 1/1B Trial of Pembrolizumab and Trametinib in Advanced NSCLC Enriched for KRAS Mutations

JTO CLINICAL AND RESEARCH REPORTS

IF3.5

2025-02-01

OAAI

Riess, Jonathan W.; Lara, Matthew S.; Luxardi, Guillaume; de Rodas, Miguel Lopez; Shimoda, Michiko; Kelly, Karen; Lara, Primo N.; Beckett, Laurel; Monjazeb, Arta; Schalper, Kurt A.; Maverakis, Emanual; Gandara, David R.

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Immune Cell Dynamics in EGFR-Mutated NSCLC Treated With Afatinib and Pembrolizumab: Results From a Phase IB Study

JTO CLINICAL AND RESEARCH REPORTS

IF3.5

2024-10-01

OAAI

Riess, Jonathan W.; Lara, Matthew S.; de Rodas, Miguel Lopez; Luxardi, Guillaume; Herbert, Samantha; Shimoda, Michiko; Kelly, Karen; Meerlev, Alexander; Moore, Elizabeth; Beckett, Laurel; Monjazeb, Arta; Schalper, Kurt; Maverakis, Emanual; Gandara, David R.

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Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity

SCIENCE IMMUNOLOGY

IF16.3

2024-04-26

PREAI

Zhang, Tianxiang; Yu, Weiwei; Cheng, Xiaoxiao; Yeung, Jacky; Ahumada, Viviana; Norris, Paul C.; Pearson, Mackenzie J.; Yang, Xuan; van Deursen, Willemijn; Halcovich, Christina; Nassar, Ala; Vesely, Mathew D.; Zhang, Yu; Zhang, Jianping; Ji, Lan; Flies, Dallas B.; Liu, Linda; Langermann, Solomon; LaRochelle, William J.; Humphrey, Rachel; Zhao, Dejian; Zhang, Qiuyu; Zhang, Jindong; Gu, Runxia; Schalper, Kurt A.; Sanmamed, Miguel F.; Chen, Lieping

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Vascular mimicry as a facilitator of melanoma brain metastasis

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2024-04-18

OAAI

Provance, Olivia K.; Oria, Victor O.; Tran, Thuy T.; Caulfield, Jasmine I.; Zito, Christopher R.; Aguirre-Ducler, Adam; Schalper, Kurt A.; Kluger, Harriet M.; Jilaveanu, Lucia B.

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Immunomodulatory and anti-tumor effect of a CCR2-targeted STING agonist iADC in human lung cancer

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Porciuncula, Angelo; Appleman, Vicky A.; Parent, Alex; Raizer, Jeff; Gregory, Richard C.; Lineberry, Neil; Abu-Yousif, Adnan O.; Schalper, Kurt A.

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Role of MGMT expression in the genomic landscape and immunogenicity in human colorectal carcinomas

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Rajendran, Barani Kumar; Zhang, Janie; Desai, Shruti; Gibson, Joanna; DiPalermo, Jassim; LoRusso, Patricia; Kong, Yong; Zhao, Hongyu; Cecchini, Michael; Schalper, Kurt Alex

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A novel humanized mouse model recapitulates the unique TME found in patients with HIV-associated NSCLC

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Juric, Melani; Kaufmann, Gabriel; Zhu, Li; Ranjan, Kishu; Agrawal, Kriti; Rajendran, Barani Kumar; Rajashekar, Jyothi K.; Zhao, Hongyu; Kluger, Yuval; Emu, Brinda; Schalper, Kurt A.; Kumar, Priti; Flavell, Richard A.; Chiorazzi, Michael

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Machine learning features derived from spatial interaction of immune cell families are associated with survival in NSCLC patients post-immunotherapy

ANNALS OF ONCOLOGY

IF65.4

2023-10-01

PREAI

Arabyarmohammadi, S.; Corredor, G.; Gregorio, M. Lopez de Rodas; Schalper, K.; Madabhushi, A.

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Digital spatial profiling of melanoma shows CD95 expression in immune cells is associated with resistance to immunotherapy

ONCOIMMUNOLOGY

IF6.3

2023-09-27

OAAI

Martinez-Morilla, Sandra; Moutafi, Myrto; Fernandez, Aileen I.; Jessel, Shlomit; Divakar, Prajan; Wong, Pok Fai; Garcia-Milian, Rolando; Schalper, Kurt A.; Kluger, Harriet M.; Rimm, David L.

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Atezolizumab plus stereotactic ablative radiotherapy for medically inoperable patients with early-stage non-small cell lung cancer: a multi-institutional phase I trial

NATURE COMMUNICATIONS

IF15.7

2023-09-02

OAAI

Monjazeb, Arta M.; Daly, Megan E.; Luxardi, Guillaume; Maverakis, Emanual; Merleev, Alexander A.; Marusina, Alina I.; Borowsky, Alexander; Mirhadi, Amin; Shiao, Stephen L.; Beckett, Laurel; Chen, Shuai; Eastham, David; Li, Tianhong; Vick, Logan V.; Mcgee, Heather M.; Lara, Frances; Garcia, Leslie; Morris, Leigh Anne; Canter, Robert J.; Riess, Jonathan W.; Schalper, Kurt A.; Murphy, William J.; Kelly, Karen

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Neuroendocrine lineage commitment of small cell lung cancers can be leveraged into p53-independent non-cytotoxic therapy

CELL REPORTS

IF6.9

2023-08-01

OAAI

Biswas, Sudipta; Kang, Kai; Ng, Kwok Peng; Radivoyevitch, Tomas; Schalper, Kurt; Zhang, Hua; Lindner, Daniel J.; Thomas, Anish; Macpherson, David; Gastman, Brian; Schrump, David S.; Wong, Kwok-Kin; Velcheti, Vamsidhar; Saunthararajah, Yogen

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Deep computational image analysis of immune cell niches reveals treatment-specific outcome associations in lung cancer

NPJ PRECISION ONCOLOGY

IF8

2023-06-01

OAAI

Barrera, Cristian; Corredor, German; Viswanathan, Vidya Sankar; Ding, Ruiwen; Toro, Paula; Fu, Pingfu; Buzzy, Christina; Lu, Cheng; Velu, Priya; Zens, Philipp; Berezowska, Sabina; Belete, Merzu; Balli, David; Chang, Han; Baxi, Vipul; Syrigos, Konstantinos; Rimm, David L.; Velcheti, Vamsidhar; Schalper, Kurt; Romero, Eduardo; Madabhushi, Anant

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Olaparib plus /- atezolizumab in patients with BRCA-mutated (BRCAmt) locally advanced unresectable or metastatic (advanced) breast cancer: an open-label, multicenter, randomized phase II trial

CANCER RESEARCH

IF16.6

2023-04-14

PREAI

Fanucci, Kristina A.; Pilat, Mary Jo; Shyr, Derek; Shyr, Yu; Boerner, Scott A.; Durecki, Diane; Noonan, Anne; Abramson, Vandana; Santa-Maria, Cesar; Han, Hyo; Nanda, Rita; Dees, Elizabeth Claire; Park, Haeseong; Buys, Saundra; Peswani, Namrata; Chew, Helen; Assad, Hadeel; Wulf, Gerburg; Richardson, Angelique; Trivedi, Meghna S.; Brufsky, Adam; Abbruzzese, James; Afghahi, Anosheh; Sharon, Elad; Schalper, Kurt; LoRusso, Patricia

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Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer

NATURE GENETICS

IF31.8

2023-04-06

OAAI

Ravi, Arvind; Hellmann, Matthew D.; Arniella, Monica B.; Holton, Mark; Freeman, Samuel S.; Naranbhai, Vivek; Stewart, Chip; Leshchiner, Ignaty; Kim, Jaegil; Akiyama, Yo; Griffin, Aaron T.; Vokes, Natalie I.; Sakhi, Mustafa; Kamesan, Vashine; Rizvi, Hira; Ricciuti, Biagio; Forde, Patrick M.; Anagnostou, Valsamo; Riess, Jonathan W.; Gibbons, Don L.; Pennell, Nathan A.; Velcheti, Vamsidhar; Digumarthy, Subba R.; Mino-Kenudson, Mari; Califano, Andrea; Heymach, John V.; Herbst, Roy S.; Brahmer, Julie R.; Schalper, Kurt A.; Velculescu, Victor E.; Henick, Brian S.; Rizvi, Naiyer; Jaenne, Pasi A.; Awad, Mark M.; Chow, Andrew; Greenbaum, Benjamin D.; Luksza, Marta; Shaw, Alice T.; Wolchok, Jedd; Hacohen, Nir; Getz, Gad; Gainor, Justin F.

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Research Directions