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R

Ralph S. Baric

University of North Carolina

147H-index
1.1KPaper Count
10.5WCitation Count
Published Papers 360
Publication Date
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Loss of nsp14-exonuclease activity impairs the replication, proofreading, fitness, and pathogenesis of SARS-CoV-2
errmBio
IF4.7
err2026-06-10
err2
PREAI
errAnderson-Daniels, Jordan; Diefenbacher, Meghan V.; Yount, Boyd L.; Meganck, Rita M.; Tse, Longping V.; Burke, Kaitlyn N.; Miranda, Hector A.; Scobey, D. Trevor; Lu, Xiaotao; Stevens, Laura; Dinnon III, Kenneth H.; Chapman, Nathaniel S.; Pajon, Camryn; Powers, John M.; Nguyen, Cameron; Graham, Rachel L.; Heaton, Nicholas S.; Baric, Ralph S.; Denison, Mark R.; Sheahan, Timothy P.
errShare
errSave
One-component ionizable amphiphilic Janus dendrimers as a delivery platform for efficient mRNA vaccine development
errScience Advances
IF12.5
err2026-03-27
err0
errOAAI
errNathan A. Ona; Dapeng Zhang; Lisa C. Lindesmith; Wook-Jin Park; Jaclynn A. Meshanni; Sydni Berkihiser; Jessica A. Vasserman; Sepideh Toshtzar; Nathanael C. Moore; Blair Williams; Benjamin Nakagawa; Ishana Baboo; Liuyan Pan; Wanting Cheng; Xiomara Mercado-López; Wendy Bonilla-Acosta; Paul D. Brewer-Jensen; Mark R. Zweigart; Yaoska I. Reyes; Michael L. Mallory; Samantha R. May; Yongfeng Zhou; Virgil Percec; Ralph S. Baric; Yongsheng Li; Drew Weissman; Elena N. Atochina-Vasserman
errShare
errSave
Mucosal vaccination in mice provides protection from diverse respiratory threats
errScience
IF45.8
err2026-02-19
err0
PREAI
errHaibo Zhang; Katharine Floyd; Zhuoqing Fang; Filipe Araujo Hoffmann; Audrey Lee; Heather Marie Froggatt; Gurpreet Bharj; Xia Xie; Haleigh B. Eppler; Jordan Mariah Santagata; Yanli Wang; Mengyun Hu; Christopher B. Fox; Prabhu S. Arunachalam; Ralph Baric; Mehul S. Suthar; Bali Pulendran
errShare
errSave
A neutralizing human antibody induces movement of the HCoV-229E receptor binding domain
errCommunications Biology
IF5.1
err2025-12-31
err0
errOAAI
errMera F. Liccione; Trevor Scobey; Heather M. Froggatt; Camryn Pajon; Boyd L. Yount; Qi Yin; Taylor N. Spence; Emmanuel B. Walter; Kevin O. Saunders; Robert J. Edwards; Ralph S. Baric; Barton F. Haynes; Derek W. Cain; Timothy P. Sheahan; Daniel Wrapp
errShare
errSave
Adaptive immune response to West Nile virus infection in the Collaborative Cross mouse model: A database of cellular phenotypes and Quantitative Trait Loci
errScientific Data
IF6.9
err2025-11-21
err0
errOAAI
errSteven Chamberlin; Jessica Graham; Sophia Jeng; Jessica Swarts; Martin Ferris; Mark Heise; Ralph S. Baric; Shannon McWeeney; Jennifer Lund; Michael Mooney
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errSave
Proteomic deconvolution of the antigen-specific serum IgA repertoire reveals clonal overlap with IgG and between monomeric and dimeric IgA following mucosal norovirus vaccination
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errPark, Juyeon; Lindesmith, Lisa C.; Brewer-Jensen, Paul D.; Reyes, Yaoska; Pickens, Whitney; Longo, Victoria; Satterwhite, Ed; Flitter, Becca; Tucker, Sean N.; Lavinder, Jason J.; Baric, Ralph S.; Georgiou, George
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errSave
Mouse-adapted SARS-CoV-2 Omicron BA.5 infection induces post-acute lung fibrosis in BALB/c mice
errJOURNAL OF VIROLOGY
IF3.8
err2025-11-01
err0
PREAI
errPowers, John M.; Leist, Sarah R.; Suryadevara, Naveenchandra; Zost, Seth J.; Binshtein, Elad; Abdelgadir, Anfal; Mallory, Michael L.; Edwards, Caitlin E.; Gully, Kendra L.; Hubbard, Miranda L.; Zweigart, Mark R.; Bailey, Alexis B.; Sheahan, Timothy P.; Crowe, James E.; Montgomery, Stephanie A.; Harkema, Jack R.; Baric, Ralph S.
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errSave
Computationally designed mRNA-launched protein nanoparticle immunogens elicit protective antibody and T cell responses in mice
errScience Translational Medicine
IF14.6
err2025-10-15
err0
PREAI
errGrace G. Hendricks; Lilit Grigoryan; Mary Jane Navarro; Nicholas J. Catanzaro; Miranda L. Hubbard; John M. Powers; Melissa Mattocks; Catherine Treichel; Alexandra C. Walls; Jimin Lee; Daniel Ellis; Jing Yang (John) Wang; Suna Cheng; Marcos C. Miranda; Adian Valdez; Cara W. Chao; Sidney Chan; Christine Men; Max R. Johnson; Samantha K. Zepeda; Sebastian Ols; Harold Hui; Sheng-Yang Wu; Victor Lujan; Hiromi Muramatsu; Paulo J.C. Lin; Molly M.H. Sung; Ying K. Tam; Elizabeth M. Leaf; Norbert Pardi; Ralph S. Baric; Bali Pulendran; David Veesler; Alexandra Schäfer; Neil P. King
errShare
errSave
Challenges of broad-spectrum antiviral drug discovery and development for emerging pathogens
errDrug Discovery Today
IF7.5
err2025-09-24
err0
PREAI
errHolli-Joi Martin; Jon-Michael Beasley; Enes Kelestemur; Zoe Sessions; Stephan Ludwig; Nathaniel J. Moorman; Ralph Baric; Eugene N. Muratov; Alexander Tropsha
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errSave
SARS-CoV-2 infection induces pro-fibrotic and pro-thrombotic foam cell formation
errNature Microbiology
IF19.4
err2025-08-22
err0
PREAI
errDiana M. Battaglia; Claire E. Post; Wenbo Yao; Angela Wahl; Lisa E. Gralinski; Hongwei Liu; Hong Dang; Victoria J. Madden; Kristen K. White; Sarah R. Leist; Kenneth H. Dinnion; Gabriela De la Cruz; Bentley R. Midkiff; Heather M. Froggatt; Kendra Gully; Mark Zweigart; J. Rachel Reader; Katherine J. Olstad; Jeffrey I. Everitt; Koen K. A. Van Rompay; Kristina De Paris; Eniko Sajti; Raymond J. Pickles; Edward P. Browne; Corbin D. Jones; Richard C. Boucher; Ralph S. Baric; J. Victor Garcia
errShare
errSave
HKU5 bat merbecoviruses engage bat and mink ACE2 as entry receptors
errNature Communications
IF15.7
err2025-07-24
err0
errOAAI
errMia Madel Alfajaro; Emma L. Keeler; Ning Li; Nicholas J. Catanzaro; I-Ting Teng; Zhe Zhao; Michael W. Grunst; Boyd Yount; Alexandra Schäfer; Danyi Wang; Arthur S. Kim; Aleksandra Synowiec; Mario A. Peña-Hernández; Samantha Zepeda; Ridwan Arinola; Ramandeep Kaur; Bridget L. Menasche; Jin Wei; Gabriel A. Russell; John Huck; Jaewon Song; Aaron Ring; Akiko Iwasaki; Rohit K. Jangra; Sanghyun Lee; David R. Martinez; Walther Mothes; Pradeep D. Uchil; John G. Doench; Alicen B. Spaulding; Ralph S. Baric; Leonid Serebryannyy; Yaroslav Tsybovsky; Tongqing Zhou; Daniel C. Douek; Craig B. Wilen
errShare
errSave
Stabilized dengue virus 2 envelope subunit vaccine redirects the neutralizing antibody response to all E-domains
errJOURNAL OF VIROLOGY
IF3.8
err2025-05-20
err0
errOAAI
errThiono, Devina J.; Samaras, Demetrios; Phan, Thanh T. N.; Zhu, Deanna R.; Shah, Ruby P.; Castillo, Izabella; Forsberg, Lawrence J.; Premkumar, Lakshmanane; Baric, Ralph S.; Tian, Shaomin; Kuhlman, Brian; de Silva, Aravinda M.
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errSave
A global collaboration for systematic analysis of broad-ranging antibodies against the SARS-CoV-2 spike protein
errCELL REPORTS
IF6.9
err2025-04-01
err0
errOAAI
errSchendel, Sharon L.; Yu, Xiaoying; Halfmann, Peter J.; Mahita, Jarjapu; Ha, Brendan; Hastie, Kathryn M.; Li, Haoyang; Bedinger, Daniel; Troup, Camille; Li, Kan; Kuzmina, Natalia; Torrelles, Jordi B.; Munt, Jennifer E.; Maddocks, Melissa; Osei-Twum, Mary; Callaway, Heather M.; Reece, Stephen; Palser, Anne; Kellam, Paul; Dennison, S. Moses; Huntwork, Richard H. C.; Horn, Gillian Q.; Abraha, Milite; Feeney, Elizabeth; Martinez-Sobrido, Luis; Pino, Paula A.; Hicks, Amberlee; Ye, Chengjin; Park, Jun-Gyu; Maingot, Billie; Periasamy, Sivakumar; Mallory, Michael; Scobey, Trevor; Lepage, Marie-Noelle; St-Amant, Natalie; Khan, Sarwat; Gambiez, Anais; Baric, Ralph S.; Bukreyev, Alexander; Gagnon, Luc; Germann, Timothy; Kawaoka, Yoshihiro; Tomaras, Georgia D.; Peters, Bjoern; Saphire, Erica Ollmann
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errSave
Molecular Evolution and Epidemiology of Norovirus GII.4 Viruses in the United States
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2025-03-01
err0
PREAI
errBarclay, Leslie; Montmayeur, Anna M.; Cannon, Jennifer L.; Mallory, Michael L.; Reyes, Yaoska, I; Wall, Helen; Baric, Ralph S.; Lindesmith, Lisa C.; Vinje, Jan; Chhabra, Preeti
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errSave
Dysregulation of lung epithelial cell homeostasis and immunity contributes to Middle East respiratory syndrome coronavirus disease severity
errMSPHERE
IF3.1
err2025-02-25
err0
errOAAI
errSims, Amy C.; Schafer, Alexandra; Okuda, Kenichi; Leist, Sarah R.; Kocher, Jacob F.; Cockrell, Adam S.; Hawkins, Padraig E.; Furusho, Minako; Jensen, Kara L.; Kyle, Jennifer E.; Burnum-Johnson, Kristin E.; Stratton, Kelly G.; Lamar, Natalie C.; Niccora, Carrie D.; Weitz, Karl K.; Smith, Richard D.; Metz, Thomas O.; Waters, Katrina M.; Boucher, Richard C.; Montgomery, Stephanie A.; Baric, Ralph S.; Sheahan, Timothy P.
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errSave
Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV
errCELL REPORTS
IF6.9
err2024-12-01
err0
errOAAI
errChao, Cara W.; Sprouse, Kaitlin R.; Miranda, Marcos C.; Catanzaro, Nicholas J.; Hubbard, Miranda L.; Addetia, Amin; Stewart, Cameron; Brown, Jack T.; Dosey, Annie; Valdez, Adian; Ravichandran, Rashmi; Hendricks, Grace G.; Ahlrichs, Maggie; Dobbins, Craig; Hand, Alexis; Mcgowan, Jackson; Simmons, Boston; Treichel, Catherine; Willoughby, Isabelle; Walls, Alexandra C.; Mcguire, Andrew T.; Leaf, Elizabeth M.; Baric, Ralph S.; Schafer, Alexandra; Veesler, David; King, Neil P.
errShare
errSave
Animal models of Long Covid: A hit-and-run disease
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-11-13
err0
errOAAI
errSchaefer, Alexandra; Leist, Sarah R.; Powers, John M.; Baric, Ralph S.
errShare
errSave
An oral non-covalent non-peptidic inhibitor of SARS-CoV-2 Mpro ameliorates viral replication and pathogenesis in vivo
errCELL REPORTS
IF6.9
err2024-11-01
err0
PREAI
errZhou, Nian E.; Tang, Su; Bian, Xuelin; Parai, Maloy K.; Krieger, Inna V.; Flores, Armando; Jaiswal, Pradeep K.; Bam, Radha; Wood, Jeremy L.; Shi, Zhe; Stevens, Laura J.; Scobey, Trevor; Diefenbacher, Meghan V.; Moreira, Fernando R.; Baric, Thomas J.; Acharya, Arjun; Shin, Joonyoung; Rathi, Manish M.; Wolff, Karen C.; Riva, Laura; Bakowski, Malina A.; Mcnamara, Case W.; Catanzaro, Nicholas J.; Graham, Rachel L.; Schultz, David C.; Cherry, Sara; Kawaoka, Yoshihiro; Halfmann, Peter J.; Baric, Ralph S.; Denison, Mark R.; Sheahan, Timothy P.; Sacchettini, James C.
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errSave
Bivalent norovirus mRNA vaccine elicits cellular and humoral responses protecting human enteroids from GII.4 infection
errNPJ VACCINES
IF6.5
err2024-10-01
err1
errOAAI
errAtochina-Vasserman, Elena N.; Lindesmith, Lisa C.; Mirabelli, Carmen; Ona, Nathan A.; Reagan, Erin K.; Brewer-Jensen, Paul D.; Mercado-Lopez, Xiomara; Shahnawaz, Hamna; Meshanni, Jaclynn A.; Baboo, Ishana; Mallory, Michael L.; Zweigart, Mark R.; May, Samantha R.; Mui, Barbara L.; Tam, Ying K.; Wobus, Christiane E.; Baric, Ralph S.; Weissman, Drew
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errSave
A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants
errNATURE COMMUNICATIONS
IF15.7
err2024-08-26
err0
errOAAI
errLiu, Xiang; Ng, Wern Hann; Zusinaite, Eva; Freitas, Joseph; Taylor, Adam; Yerragunta, Venugopal; Aavula, Shukra Madhaha; Gorriparthi, Sambaiah; Ponsekaran, Santhakumar; Bonda, Rama Lakshmi; Mani, Priyanka; Nimmagadda, Sridevi V.; Wang, Sainan; Lello, Laura Sandra; Zaid, Ali; Dua, Ujjwal; Taft-Benz, Sharon A.; Anderson, Elizabeth; Baxter, Victoria K.; Sarkar, Sanjay; Ling, Zheng L.; Ashhurst, Thomas M.; Cheng, Samuel M. S.; Pattnaik, Priyabrata; Kanakasapapathy, Anand Kumar; Baric, Ralph S.; Burt, Felicity J.; Peiris, Malik; Heise, Mark T.; King, Nicholas J. C.; Merits, Andres; Lingala, Rajendra; Mahalingam, Suresh
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Research Directions

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Co-authors
Cooperation Journals
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Ian A. Wilson
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D
Dennis R. Burton
H-index: 172 · Papers: 800
B
Bernhard Ø. Palsson
H-index: 166 · Papers: 1.2K
R
Richard Smith
H-index: 160 · Papers: 4.8W
M
Michael Diamond
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