Peter J. Ratcliffe - Publications, H-index & Citations

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Peter J. Ratcliffe

university of oxford

125H-index

633Paper Count

7.8WCitation Count

Published Papers 193

Publication Date

Hypoxic regulation of chromatin and gene transcription

Communications Biology

IF5.1

2026-03-25

OAAI

Jessica D. Kindrick; Olivia Lombardi; Silvia Halim; Veronique N. Lafleur; Cindy H. Chau; William D. Figg; Peter J. Ratcliffe; David R. Mole

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HIFα isoform specific activities drive cell-type specificity of VHL-associated oncogenesis

Nature Communications

IF15.7

2025-10-16

OAAI

Joanna D.C.C. Lima; Madeleine Hooker; Ran Li; Ayslan B. Barros; Norma Masson; Christopher W. Pugh; David R. Mole; Julie Adam; Peter J. Ratcliffe; Samvid Kurlekar

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Conserved patterns of transcriptional dysregulation, heterogeneity, and cell states in clear cell kidney cancer

CELL REPORTS

IF6.9

2025-01-01

PREAI

Lombardi, Olivia; Li, Ran; Jabbar, Faiz; Evans, Hannah; Halim, Silvia; Lima, Joanna D. C. C.; Browning, Lisa; Byrne, Helen M.; Choudhry, Hani; Ratcliffe, Peter J.; Mole, David R.

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Hif-2α programs oxygen chemosensitivity in chromaffin cells

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-08-06

OAAI

Prange-Barczynska, Maria; Jones, Holly A.; Sugimoto, Yoichiro; Cheng, Xiaotong; Lima, Joanna D. C. C.; Ratnayaka, Indrika; Douglas, Gillian; Buckler, Keith J.; Ratcliffe, Peter J.; Keeley, Thomas P.; Bishop, Tammie

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N-terminal cysteine acetylation and oxidation patterns may define protein stability

NATURE COMMUNICATIONS

IF15.7

2024-06-25

OAAI

Heathcote, Karen C.; Keeley, Thomas P.; Myllykoski, Matti; Lundekvam, Malin; McTiernan, Nina; Akter, Salma; Masson, Norma; Ratcliffe, Peter J.; Arnesen, Thomas; Flashman, Emily

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Identification of early oncogenic lesions following concomitant Vhl and Pbrm1 loss in the murine kidney

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Lima, Joanna; Kurlekar, Samvid; Masson, Norma; Barros, Ayslan B.; Soares, Maria Fernanda; Pugh, Christopher W.; Adam, Julie; Ratcliffe, Peter J.

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Transcriptional programs underpinning reoccurring cancer cell states, plasticity and tumour phylogenies in clear cell kidney cancer

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Lombardi, Olivia; Li, Ran; Browning, Lisa; Jabbar, Faiz; Evans, Hannah; Ratcliffe, Peter J.; Mole, David R.

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HIF1A and HIF2A differentially contribute to early and adaptive changes following in vivo Vhl inactivation in the kidney

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Kurlekar, Samvid; Lima, Joanna; Barros, Ayslan B.; Masson, Norma; Zhai, Sophia; Pugh, Christopher W.; Adam, Julie; Ratcliffe, Peter J.

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Oncogenic Cell Tagging and Single-Cell Transcriptomics Reveal Cell Type-Specific and Time-Resolved Responses to Vhl Inactivation in the Kidney

CANCER RESEARCH

IF16.6

2024-03-19

OAAI

Kurlekar, Samvid; Lima, Joanna D. C. C.; Li, Ran; Lombardi, Olivia; Masson, Norma; Barros, Ayslan B.; Pontecorvi, Virginia; Mole, David R.; Pugh, Christopher W.; Adam, Julie; Ratcliffe, Peter J.

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Deficiency of factor- inhibiting HIF creates a tumor- promoting immune microenvironment

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-02-29

OAAI

Ma, Jingyi; Al Moussawi, Khatoun; Lou, Hantao; Chan, Hok Fung; Wang, Yihua; Chadwick, Joseph; Phetsouphanh, Chansavath; Slee, Elizabeth A.; Zhong, Shan; Leissing, Thomas M.; Roth, Andrew; Qin, Xiao; Chen, Shuo; Yin, Jie; Ratnayaka, Indrika; Hu, Yang; Louphrasitthiphol, Pakavarin; Taylor, Lewis; Bettencourt, Paulo J. G.; Muers, Mary; Greaves, David R.; Mcshane, Helen; Goldin, Robert; Soilleux, Elizabeth J.; Coleman, Mathew L.; Ratcliffe, Peter J.; Lu, Xin

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Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen-sensing pathways in mammalian cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-09-01

OAAI

Tian, Ya-Min; Holdship, Philip; To, Trang Quynh; Ratcliffe, Peter J.; Keeley, Thomas P.

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Evidence for a 'pathway tuning' model of VHL-associated renal carcinoma

CANCER RESEARCH

IF16.6

2023-08-15

PREAI

Ratcliffe, Peter J.

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Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

188

OAAI

Bishop, Tammie; Gallagher, Denis; Pascual, Alberto; Lygate, Craig A.; de Bono, Joseph P.; Nicholls, Lynn G.; Ortega-Saenz, Patricia; Oster, Henrik; Wijeyekoon, Bhathiya; Sutherland, Andrew I.; Grosfeld, Alexandra; Aragones, Julian; Schneider, Martin; van Geyte, Katie; Teixeira, Dania; Diez-Juan, Antonio; Lopez-Barneo, Jose; Channon, Keith M.; Maxwell, Patrick H.; Pugh, Christopher W.; Davies, Alun M.; Carmeliet, Peter; Ratcliffe, Peter J.

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Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

221

OAAI

Lavista-Llanos, S; Centanin, L; Irisarri, M; Russo, DM; Gleadle, JM; Bocca, SN; Muzzopappa, M; Ratcliffe, PJ; Wappner, P

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Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

933

OAAI

Raval, RR; Lau, KW; Tran, MGB; Sowter, HM; Mandriota, SJ; Li, JL; Pugh, CW; Maxwell, PH; Harris, AL; Ratcliffe, PJ

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Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma

LIFE SCIENCE ALLIANCE

IF2.9

2023-02-01

OAAI

Lafleur, Veronique N.; Halim, Silvia; Choudhry, Hani; Ratcliffe, Peter J.; Mole, David R.

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Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature

CELL REPORTS

IF6.9

2022-11-01

OAAI

Lombardi, Olivia; Li, Ran; Halim, Silvia; Choudhry, Hani; Ratcliffe, Peter J.; Mole, David R.

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A global view of the aspiring physician-scientist

ELIFE

IF0

2022-09-13

OAAI

Williams, Christopher S.; Rathmell, W. Kimryn; Carethers, John M.; Harper, Diane M.; Lo, Ym Dennis; Ratcliffe, Peter J.; Zaidi, Mone

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Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2022-09-12

OAAI

Sugimoto, Yoichiro; Ratcliffe, Peter J.

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Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-08-05

OAAI

Cockman, Matthew E.; Sugimoto, Yoichiro; Pegg, Hamish B.; Masson, Norma; Salah, Eidarus; Tumber, Anthony; Flynn, Helen R.; Kirkpatrick, Joanna M.; Schofield, Christopher J.; Ratcliffe, Peter J.

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Research Directions