Kimmo Rantalainen - Publications, H-index & Citations

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Kimmo Rantalainen

Scripps Research Institute

19H-index

44Paper Count

1.4KCitation Count

Published Papers 25

Publication Date

Virus glycoprotein nanodisc platform for vaccine analytics

Nature Communications

IF15.7

2026-02-10

OAAI

Kimmo Rantalainen; Alessia Liguori; Gabriel Ozorowski; Claudia Flynn; Jon M. Steichen; Olivia M. Swanson; Patrick J. Madden; Sabyasachi Baboo; Swastik Phulera; Anant Gharpure; Danny Lu; Oleksandr Kalyuzhniy; Patrick Skog; Sierra Terada; Monolina Shil; Jolene K. Diedrich; Erik Georgeson; Ryan Tingle; Saman Eskandarzadeh; Wen-Hsin Lee; Nushin Alavi; Diana Goodwin; Michael Kubitz; Sonya Amirzehni; Sunny Himansu; Devin Sok; Jeong Hyun Lee; John R. Yates; James C. Paulson; Shane Crotty; Torben Schiffner; Andrew B. Ward; William R. Schief

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Cryo-EM structures of antibodies elicited by germline-targeting HIV MPER epitope scaffolds

Cell Reports

IF6.9

2026-01-12

OAAI

Jiachen Huang; Olivia M. Swanson; Kimmo Rantalainen; Monica L. Fernández-Quintero; Johannes R. Loeffler; Ryan Tingle; Erik Georgeson; Nicole Phelps; Gabriel Ozorowski; Torben Schiffner; William R. Schief; Andrew B. Ward

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Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models

Science Immunology

IF16.3

2025-10-17

PREAI

Zhenfei Xie; Xuesong Wang; Yu Yan; Jon M. Steichen; Krystal M. Ma; Christopher A. Cottrell; Eleonora Melzi; Maria Bottermann; Paula Maldonado Villavicencio; Kimmo Rantalainen; Torben Schiffner; John E. Warner; Stephanie R. Weldon; Thavaleak Prum; Jordan R. Ellis-Pugh; Jonathan L. Torres; Abigail M. Jackson; Claudia T. Flynn; Gabriel Ozorowski; Sunny Himansu; Andrea Carfi; Andrew B. Ward; Usha Nair; William R. Schief; Facundo D. Batista

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Vaccination induces broadly neutralizing antibody precursors to HIV gp41 (vol 25, pg 1073, 2024)

NATURE IMMUNOLOGY

IF27.6

2024-06-14

OAAI

Schiffner, Torben; Phung, Ivy; Ray, Rashmi; Irimia, Adriana; Tian, Ming; Swanson, Olivia; Lee, Jeong Hyun; Lee, Chang-Chun D.; Marina-Zarate, Ester; Cho, So Yeon; Huang, Jiachen; Ozorowski, Gabriel; Skog, Patrick D.; Serra, Andreia M.; Rantalainen, Kimmo; Allen, Joel D.; Baboo, Sabyasachi; Rodriguez, Oscar L.; Himansu, Sunny; Zhou, Jianfu; Hurtado, Jonathan; Flynn, Claudia T.; McKenney, Katherine; Havenar-Daughton, Colin; Saha, Swati; Shields, Kaitlyn; Schultze, Steven; Smith, Melissa L.; Liang, Chi-Hui; Toy, Laura; Pecetta, Simone; Lin, Ying-Cing; Willis, Jordan R.; Sesterhenn, Fabian; Kulp, Daniel W.; Hu, Xiaozhen; Cottrell, Christopher A.; Zhou, Xiaoya; Ruiz, Jennifer; Wang, Xuesong; Nair, Usha; Kirsch, Kathrin H.; Cheng, Hwei-Ling; Davis, Jillian; Kalyuzhniy, Oleksandr; Liguori, Alessia; Diedrich, Jolene K.; Ngo, Julia T.; Lewis, Vanessa; Phelps, Nicole; Tingle, Ryan D.; Spencer, Skye; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Eskandarzadeh, Saman; Elsliger, Marc A.; Amara, Rama R.; Landais, Elise; Briney, Bryan; Burton, Dennis R.; Carnathan, Diane G.; Silvestri, Guido; Watson, Corey T.; Yates, John R.; Paulson, James C.; Crispin, Max; Grigoryan, Gevorg; Ward, Andrew B.; Sok, Devin; Alt, Frederick W.; Wilson, Ian A.; Batista, Facundo D.; Crotty, Shane; Schief, William R.

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Affinity gaps among B cells in germinal centers drive the selection of MPER precursors

NATURE IMMUNOLOGY

IF27.6

2024-05-30

OAAI

Ray, Rashmi; Schiffner, Torben; Wang, Xuesong; Yan, Yu; Rantalainen, Kimmo; Lee, Chang-Chun David; Parikh, Shivang; Reyes, Raphael A.; Dale, Gordon A.; Lin, Ying-Cing; Pecetta, Simone; Giguere, Sophie; Swanson, Olivia; Kratochvil, Sven; Melzi, Eleonora; Phung, Ivy; Madungwe, Lisa; Kalyuzhniy, Oleksandr; Warner, John; Weldon, Stephanie R.; Tingle, Ryan; Lamperti, Edward; Kirsch, Kathrin H.; Phelps, Nicole; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Nair, Usha; Crotty, Shane; Wilson, Ian A.; Schief, William R.; Batista, Facundo D.

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Vaccination induces broadly neutralizing antibody precursors to HIV gp41

NATURE IMMUNOLOGY

IF27.6

2024-05-30

OAAI

Schiffner, Torben; Phung, Ivy; Ray, Rashmi; Irimia, Adriana; Tian, Ming; Swanson, Olivia; Lee, Jeong Hyun; Lee, Chang-Chun D.; Marina-Zarate, Ester; Cho, So Yeon; Huang, Jiachen; Ozorowski, Gabriel; Skog, Patrick D.; Serra, Andreia M.; Rantalainen, Kimmo; Allen, Joel D.; Baboo, Sabyasachi; Rodriguez, Oscar L.; Himansu, Sunny; Zhou, Jianfu; Hurtado, Jonathan; Flynn, Claudia T.; Mckenney, Katherine; Havenar-Daughton, Colin; Saha, Swati; Shields, Kaitlyn; Schulze, Steven; Smith, Melissa L.; Liang, Chi-Hui; Toy, Laura; Pecetta, Simone; Lin, Ying-Cing; Willis, Jordan R.; Sesterhenn, Fabian; Kulp, Daniel W.; Hu, Xiaozhen; Cottrell, Christopher A.; Zhou, Xiaoya; Ruiz, Jennifer; Wang, Xuesong; Nair, Usha; Kirsch, Kathrin H.; Cheng, Hwei-Ling; Davis, Jillian; Kalyuzhniy, Oleksandr; Liguori, Alessia; Diedrich, Jolene K.; Ngo, Julia T.; Lewis, Vanessa; Phelps, Nicole; Tingle, Ryan D.; Spencer, Skye; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Eskandarzadeh, Saman; Elsliger, Marc A.; Amara, Rama R.; Landais, Elise; Briney, Bryan; Burton, Dennis R.; Carnathan, Diane G.; Silvestri, Guido; Watson, Corey T.; Yates III, John R.; Paulson, James C.; Crispin, Max; Grigoryan, Gevorg; Ward, Andrew B.; Sok, Devin; Alt, Frederick W.; Wilson, Ian A.; Batista, Facundo D.; Crotty, Shane; Schief, William R.

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Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization

PLOS PATHOGENS

IF4.9

2023-10-30

OAAI

Ringe, Rajesh P.; Colin, Philippe; Ozorowski, Gabriel; Allen, Joel D.; Yasmeen, Anila; Seabright, Gemma E.; Lee, Jeong Hyun; Antanasijevic, Aleksandar; Rantalainen, Kimmo; Ketas, Thomas; Moore, John P.; Ward, Andrew B.; Crispin, Max; Klasse, P. J.

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Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions

CELL REPORTS MEDICINE

IF10.6

2023-04-01

OAAI

Caniels, Tom G.; Medina-Ramirez, Max; Zhang, Jinsong; Sarkar, Anita; Kumar, Sonu; LaBranche, Alex; Derking, Ronald; Allen, Joel D.; Snitselaar, Jonne L.; Capella-Pujol, Joan; Sanchez, Ivan del Moral; Yasmeen, Anila; Diaz, Marilyn; Aldon, Yoann; Bijl, Tom P. L.; Venkatayogi, Sravani; Beem, Joshua S. Martin; Newman, Amanda; Jiang, Chuancang; Lee, Wen-Hsin; Pater, Maarten; Burger, Judith A.; Breemen, Marielle J. van; Taeye, Steven W. de; Rantalainen, Kimmo; LaBranche, Celia; Saunders, Kevin O.; Montefiori, David; Ozorowski, Gabriel; Ward, Andrew B.; Crispin, Max; Moore, John P.; Klasse, Per Johan; Haynes, Barton F.; Wilson, Ian A.; Wiehe, Kevin; Verkoczy, Laurent; Sanders, Rogier W.

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Immunogenicity of a germline-targeting nanoparticle in knock-in mice expressing human B cell receptors of the HIV gp41 neutralizing antibody, DH511

JOURNAL OF IMMUNOLOGY

IF3.4

2022-05-01

PREAI

Cain, Derek Wilson; Tian, Ming; Schiffner, Torben; Rantalainen, Kimmo; Saunders, Kevin O.; Wiehe, Kevin; Watts, Brian; Ward, Andrew; Ofek, Gilad; Alt, Frederick W.; Haynes, Barton F.; Schief, William R.; Alam, S. Munir

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Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM

NATURE COMMUNICATIONS

IF15.7

2021-08-10

OAAI

Antanasijevic, Aleksandar; Sewall, Leigh M.; Cottrell, Christopher A.; Carnathan, Diane G.; Jimenez, Luis E.; Ngo, Julia T.; Silverman, Jennifer B.; Groschel, Bettina; Georgeson, Erik; Bhiman, Jinal; Bastidas, Raiza; LaBranche, Celia; Allen, Joel D.; Copps, Jeffrey; Perrett, Hailee R.; Rantalainen, Kimmo; Cannac, Fabien; Yang, Yuhe R.; de la Pena, Alba Torrents; Rocha, Rebeca Froes; Berndsen, Zachary T.; Baker, David; King, Neil P.; Sanders, Rogier W.; Moore, John P.; Crotty, Shane; Crispin, Max; Montefiori, David C.; Burton, Dennis R.; Schief, William R.; Silvestri, Guido; Ward, Andrew B.

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Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike

CELL REPORTS

IF6.9

2021-04-01

OAAI

Derking, Ronald; Allen, Joel D.; Cottrell, Christopher A.; Sliepen, Kwinten; Seabright, Gemma E.; Lee, Wen-Hsin; Aldon, Yoann; Rantalainen, Kimmo; Antanasijevic, Aleksandar; Copps, Jeffrey; Yasmeen, Anila; Cupo, Albert; Portillo, Victor M. Cruz; Poniman, Meliawati; Bol, Niki; van Der Woude, Patricia; de Taeye, Steven W.; van den Kerkhof, Tom L. G. M.; Klasse, P. J.; Ozorowski, Gabriel; van Gils, Marit J.; Moore, John P.; Ward, Andrew B.; Crispin, Max; Sanders, Rogier W.

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HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies

CELL REPORTS

IF6.9

2020-04-01

OAAI

Rantalainen, Kimmo; Berndsen, Zachary T.; Antanasijevic, Aleksandar; Schiffner, Torben; Zhang, Xi; Lee, Wen-Hsin; Torres, Jonathan L.; Zhang, Lei; Irimia, Adriana; Copps, Jeffrey; Zhou, Kenneth H.; Kwon, Young D.; Law, William H.; Schramm, Chaim A.; Verardi, Raffaello; Krebs, Shelly J.; Kwong, Peter D.; Doria-Rose, Nicole A.; Wilson, Ian A.; Zwick, Michael B.; Yates, John R., III; Schief, William R.; Ward, Andrew B.

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An MPER antibody neutralizes HIV-1 using germline features shared among donors

NATURE COMMUNICATIONS

IF15.7

2019-11-26

OAAI

Zhang, Lei; Irimia, Adriana; He, Lingling; Landais, Elise; Rantalainen, Kimmo; Leaman, Daniel P.; Vollbrecht, Thomas; Stano, Armando; Sands, Daniel, I; Kim, Arthur S.; Poignard, Pascal; Burton, Dennis R.; Murrell, Ben; Ward, Andrew B.; Zhu, Jiang; Wilson, Ian A.; Zwick, Michael B.; Miiro, George; Serwanga, Jennifer; Pozniak, Anton; McPhee, Dale; Manigart, Oliver; Mwananyanda, Lawrence; Karita, Etienne; Inwoley, Andre; Jaoko, Walter; DeHovitz, Jack; Bekker, Linda-Gail; Pitisuttithum, Punnee; Paris, Robert; Allen, Susan

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PLOS PATHOGENS

IF4.9

2019-07-15

OAAI

de la Pena, Alba Torrents; Rantalainen, Kimmo; Cottrell, Christopher A.; Allen, Joel D.; van Gils, Marit J.; Torres, Jonathan L.; Crispin, Max; Sanders, Rogier W.; Ward, Andrew B.

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Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence

NATURE COMMUNICATIONS

IF15.7

2019-05-29

119

OAAI

Sliepen, Kwinten; Han, Byung Woo; Bontjer, Ilja; Mooij, Petra; Garces, Fernando; Behrens, Anna-Janina; Rantalainen, Kimmo; Kumar, Sonu; Sarkar, Anita; Brouwer, Philip J. M.; Hua, Yuanzi; Tolazzi, Monica; Schermer, Edith; Torres, Jonathan L.; Ozorowski, Gabriel; van der Woude, Patricia; de la Pena, Alba Torrents; van Breemen, Marielle J.; Camacho-Sanchez, Juan Miguel; Burger, Judith A.; Medina-Ramirez, Max; Gonzalez, Nuria; Alcami, Jose; LaBranche, Celia; Scarlatti, Gabriella; van Gils, Marit J.; Crispin, Max; Montefiori, David C.; Ward, Andrew B.; Koopman, Gerrit; Moore, John P.; Shattock, Robin J.; Bogers, Willy M.; Wilson, Ian A.; Sanders, Rogier W.

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Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer

NATURE COMMUNICATIONS

IF15.7

2018-09-12

111

OAAI

Cao, Liwei; Pauthner, Matthias; Andrabi, Raiees; Rantalainen, Kimmo; Berndsen, Zachary; Diedrich, Jolene K.; Menis, Sergey; Sok, Devin; Bastidas, Raiza; Park, Sung-Kyu Robin; Delahunty, Claire M.; He, Lin; Guenaga, Javier; Wyatt, Richard T.; Schief, William R.; Ward, Andrew B.; Yates, John R., III; Burton, Dennis R.; Paulson, James C.

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Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design

CELL REPORTS

IF6.9

2018-06-01

OAAI

Rantalainen, Kimmo; Berndsen, Zachary T.; Murrell, Sasha; Cao, Liwei; Omorodion, Oluwarotimi; Torres, Jonathan L.; Wu, Mengyu; Umotoy, Jeffrey; Copps, Jeffrey; Poignard, Pascal; Landais, Elise; Paulson, James C.; Wilson, Ian A.; Ward, Andrew B.

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HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage

IMMUNITY

IF26.3

2017-11-01

OAAI

Landais, Elise; Murrell, Ben; Briney, Bryan; Murrell, Sasha; Rantalainen, Kimmo; Berndsen, Zachary T.; Ramos, Alejandra; Wickramasinghe, Lalinda; Smith, Melissa Laird; Eren, Kemal; de Val, Natalia; Wu, Mengyu; Cappelletti, Audrey; Umotoy, Jeffrey; Lie, Yolanda; Wrin, Terri; Algate, Paul; Chan-Hui, Po-Ying; Karita, Etienne; Ward, Andrew B.; Wilson, Ian A.; Burton, Dennis R.; Smith, Davey; Pond, Sergei L. Kosakovsky; Poignard, Pascal

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Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers

JOURNAL OF VIROLOGY

IF3.8

2017-08-01

OAAI

Ringe, Rajesh P.; Ozorowski, Gabriel; Rantalainen, Kimmo; Struwe, Weston B.; Matthews, Katie; Torres, Jonathan L.; Yasmeen, Anila; Cottrell, Christopher A.; Ketas, Thomas J.; LaBranche, Celia C.; Montefiori, David C.; Cupo, Albert; Crispin, Max; Wilson, Ian A.; Ward, Andrew B.; Sanders, Rogier W.; Klasse, P. J.; Moore, John P.

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Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes

JOURNAL OF VIROLOGY

IF3.8

2017-06-15

OAAI

Ringe, Rajesh P.; Ozorowski, Gabriel; Yasmeen, Anila; Cupo, Albert; Portillo, Victor M. Cruz; Pugach, Pavel; Golabek, Michael; Rantalainen, Kimmo; Holden, Lauren G.; Cottrell, Christopher A.; Wilson, Ian A.; Sanders, Rogier W.; Ward, Andrew B.; Klasse, P. J.; Moore, John P.

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Research Directions