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Bart De Strooper

uk dementia research institute at university college london and kuleuven

142H-index
684Paper Count
7.7WCitation Count
Published Papers 292
Publication Date
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Recent Cochrane review has serious flaws: A perspective of clinicians and researchers from around the world
errAlzheimers & Dementia
IF11.1
err2026-07-29
err0
errOAAI
errHeather M. Snyder; Malavika P. Tampi; Paul S. Aisen; Ricardo Allegri; Liana G. Apostolova; Alireza Atri; Sheena Aurora; Paulo Caramelli; Lucia Crivelli; Jeffrey Cummings; Bart de Strooper; Nick C. Fox; Lea Tenenholz Grinberg; John Hardy; Bruce T. Lamb; Allan Levey; Oscar Lopez; Catherine Mummery; Ricardo Nitrini; Sarah Pahlke; Ronald C. Petersen; K. Joanne Pike; Anton P. Porsteinsson; Gil D. Rabinovici; Michael Rafii; Rema Raman; Marwan N. Sabbagh; Stephen P. Salloway; Philip Scheltens; Jonathan M. Schott; Dennis J. Selkoe; Gustavo Sevlever; Reisa Sperling; Malu Gamez Tansey; Christopher van Dyck; Henrik Zetterberg; Maria C. Carrillo
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errSave
Human microglial transitions at the Aβ–tau inflection point associate with divergent pathways to dementia and resilience
errNature Medicine
IF50
err2026-06-04
err0
errOAAI
errAshley Lu; Wei-Ting Chen; Maria Dalby; Diego Sainz Garcia; Marisa Vanheusden; Luuk E. de Vries; Veerle van Lieshout; Araks Martirosyan; Katleen Craessaerts; Sebastiaan Moonen; Magdalena Zielonka; Iordana Chrysidou; Anke Misbaer; Leen Wolfs; Benjamin Pavie; Dick Swaab; Dietmar Rudolf Thal; Inge Huitinga; Annemieke Rozemuller; Susan Karijn Rohde; Marc Hulsman; Henne Holstege; Rita Balice-Gordon; Niels Plath; Mark Fiers; Bart De Strooper
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errSave
Tracking the turning point in Alzheimer’s disease
errScience
IF45.8
err2026-04-30
err0
PREAI
errBart De Strooper; Henrik Zetterberg
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errSave
The Alzheimer’s therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia
errNature Neuroscience
IF20
err2025-11-24
err0
errOAAI
errGiulia Albertini; Magdalena Zielonka; Marie-Lynn Cuypers; An Snellinx; Ciana Xu; Suresh Poovathingal; Marta Wojno; Kristofer Davie; Veerle van Lieshout; Katleen Craessaerts; Leen Wolfs; Emanuela Pasciuto; Tom Jaspers; Katrien Horré; Lurgarde Serneels; Mark Fiers; Maarten Dewilde; Bart De Strooper
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errSave
Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health
errJournal of Internal Medicine
IF9.2
err2025-11-06
err0
errOAAI
errSilvia Maioli; Ivan Nalvarte; Maria Ankarcrona; Marianne Schultzberg; Kristen L. Zuloaga; Julen Goikolea; Pieter Jelle Visser; Bart De Strooper; Bengt Winblad; Paola Pizzo; Pete A. Williams; Patricia Rodriguez-Rodriguez; Luana Naia
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errSave
The chloride intracellular channel 1 (CLIC1) is essential for microglial morphodynamics and neuroinflammation
errScience Advances
IF12.5
err2025-10-22
err0
PREAI
errAli Rifat; Tom Bickel; Patricia Kreis; Thorsten Trimbuch; Julia Onken; Andranik Ivanov; Giulia Albertini; Dieter Beule; Michele Mazzanti; Harpreet Singh; Britta J. Eickholt; Bart De Strooper; Jörg R. P. Geiger; Christian Madry
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errSave
The APOE isoforms differentially shape the transcriptomic and epigenomic landscapes of human microglia xenografted into a mouse model of Alzheimer's disease
errNATURE COMMUNICATIONS
IF15.7
err2025-05-27
err0
errOAAI
errMurphy, Kitty B.; Hu, Di; Wolfs, Leen; Rohde, Susan K.; Fauro, Gonzalo Leguia; Geric, Ivana; Mancuso, Renzo; De Strooper, Bart; Marzi, Sarah J.
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errSave
Lecanemab preferentially binds to smaller aggregates present at early Alzheimer's disease
errALZHEIMERS & DEMENTIA
IF11.1
err2025-04-16
err1
PREAI
errFertan, E; Lam, JYL; Albertini, G; Dewilde, M; Wu, YZ; Akingbade, OES; Böken, D; English, EA; De Strooper, B; Klenerman, D
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errSave
Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein
errFLUIDS AND BARRIERS OF THE CNS
IF6.2
err2025-01-30
err0
errOAAI
errCuypers, Marie-Lynn; Jaspers, Tom; Clerckx, Jarne; Leekens, Simon; Cawthorne, Christopher; Bormans, Guy; Cleeren, Frederik; Geukens, Nick; De Strooper, Bart; Dewilde, Maarten
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errSave
Pyroptosis in Alzheimer's disease: cell type-specific activation in microglia, astrocytes and neurons (Vol 145, pg 175, 2023)
errACTA NEUROPATHOLOGICA
IF9.3
err2024-12-23
err0
PREAI
errMoonen, Sebastiaan; Koper, Marta J.; Van Schoor, Evelien; Schaeverbeke, Jolien M.; Vandenberghe, Rik; von Arnim, Christine A. F.; Tousseyn, Thomas; De Strooper, Bart; Thal, Dietmar Rudolf
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errSave
Clearance of beta-amyloid and tau aggregates is size dependent and altered by an inflammatory challenge
errBRAIN COMMUNICATIONS
IF4.5
err2024-12-14
err0
errOAAI
errFertan, Emre; Hung, Christy; Danial, John S. H.; Lam, Jeff Y. L.; Preman, Pranav; Albertini, Giulia; English, Elizabeth A.; Boeken, Dorothea; Livesey, Frederick J.; De Strooper, Bart; Patani, Rickie; Klenerman, David
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errSave
Homeostatic microglia initially seed and activated microglia later reshape amyloid plaques in Alzheimer's Disease
errNATURE COMMUNICATIONS
IF15.7
err2024-12-05
err0
errOAAI
errBaligacs, Nora; Albertini, Giulia; Borrie, Sarah C.; Serneels, Lutgarde; Pridans, Clare; Balusu, Sriram; De Strooper, Bart
errShare
errSave
APOE from astrocytes restores Alzheimer's Aβ-pathology and DAM-like responses in APOE deficient microglia
errEMBO MOLECULAR MEDICINE
IF8.3
err2024-11-11
err1
PREAI
errPreman, Pranav; Moechars, Daan; Fertan, Emre; Wolfs, Leen; Serneels, Lutgarde; Shah, Disha; Lamote, Jochen; Poovathingal, Suresh; Snellinx, An; Mancuso, Renzo; Balusu, Sriram; Klenerman, David; Arranz, Amaia M.; Fiers, Mark; De Strooper, Bart
errShare
errSave
Deep proteomic analysis of microglia reveals fundamental biological differences between model systems
errCELL REPORTS
IF6.9
err2024-11-01
err1
errOAAI
errLloyd, Amy F.; Martinez-Muriana, Anna; Davis, Emma; Daniels, Michael J. D.; Hou, Pengfei; Mancuso, Renzo; Brenes, Alejandro J.; Sinclair, Linda V.; Geric, Ivana; Snellinx, An; Craessaerts, Katleen; Theys, Tom; Fiers, Mark; De Strooper, Bart; Howden, Andrew J. M.
errShare
errSave
Divisions over the regulation of lecanemab
errLANCET
IF88.5
err2024-11-01
err0
PREAI
errDe Strooper, Bart; Haass, Christian; Hardy, John; Zetterberg, Henrik
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errSave
Inhibition of an Alzheimer's disease-associated form of necroptosis rescues neuronal death in mouse models
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-10-30
err1
PREAI
errKoper, Marta J.; Moonen, Sebastiaan; Ronisz, Alicja; Ospitalieri, Simona; Callaerts-Vegh, Zsuzsanna; T'Syen, Dries; Rabe, Sabine; Staufenbiel, Matthias; De Strooper, Bart; Balusu, Sriram; Thal, Dietmar Rudolf
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errSave
Regulated cell death in neurodegeneration: pathways and therapeutic horizons
errACTA NEUROPATHOLOGICA
IF9.3
err2024-09-24
err0
PREAI
errThal, Dietmar Rudolf; De Strooper, Bart
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errSave
Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response
errCELL REPORTS
IF6.9
err2024-09-01
err1
errOAAI
errGermeys, Christine; Vandoorne, Tijs; Davie, Kristofer; Poovathingal, Suresh; Heeren, Kara; Vermeire, Wendy; Nami, Fatemeharefeh; Moisse, Matthieu; Quaegebeur, Annelies; Sierksma, Annerieke; Rue, Laura; Sicart, Adria; Eykens, Caroline; De Cock, Lenja; De Strooper, Bart; Carmeliet, Peter; Van Damme, Philip; De Bock, Katrien; van den Bosch, Ludo
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errSave
Proteome-wide analysis identifies plasma immune regulators of amyloid-beta progression
errBRAIN BEHAVIOR AND IMMUNITY
IF7.6
err2024-08-01
err0
errOAAI
errDuggan, Michael R.; Gomez, Gabriela T.; Joynes, Cassandra M.; Bilgel, Murat; Chen, Jingsha; Fattorelli, Nicola; Hohman, Timothy J.; Mancuso, Renzo; Cordon, Jenifer; Castellano, Tonnar; Koran, Mary Ellen I.; Candia, Julian; Lewis, Alexandria; Moghekar, Abhay; Ashton, Nicholas J.; Kac, Przemys law R.; Karikari, Thomas K.; Blennow, Kaj; Zetterberg, Henrik; Martinez-Muriana, Anna; De Strooper, Bart; Thambisetty, Madhav; Ferrucci, Luigi; Gottesman, Rebecca F.; Coresh, Josef; Resnick, Susan M.; Walker, Keenan A.
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errSave
The Alzheimer's disease-linked protease BACE2 cleaves VEGFR3 and modulates its signaling
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2024-06-18
err1
errOAAI
errSchmidt, Andree; Hrupka, Brian; van Bebber, Frauke; Kumar, Sanjay Sunil; Feng, Xiao; Tschirner, Sarah K.; Assfalg, Marlene; Mueller, Stephan A.; Hilger, Laura Sophie; Hofmann, Laura I.; Pigoni, Martina; Jocher, Georg; Voytyuk, Iryna; Self, Emily L.; Ito, Mana; Hyakkoku, Kana; Yoshimura, Akimasa; Horiguchi, Naotaka; Feederle, Regina; De Strooper, Bart; Schulte-Merker, Stefan; Lammert, Eckhard; Moechars, Dieder; Schmid, Bettina; Lichtenthaler, Stefan F.
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Research Directions

No research directions
Co-authors
Cooperation Journals
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Luigi Ferrucci
H-index: 237 · Papers: 2.6K
K
Kaj Blennow
H-index: 214 · Papers: 3.6K
J
John Hardy
H-index: 207 · Papers: 1.9K
P
Peter Carmeliet
H-index: 192 · Papers: 1.4K
H
Henrik Zetterberg
H-index: 190 · Papers: 3.7K
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