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Christopher E. Goldring

University of Liverpool

53H-index
219Paper Count
1.2WCitation Count
Published Papers 99
Publication Date
Quantitative systems toxicology: modelling to mechanistically understand and predict drug safety
err2025-10-27
err0
PREAI
errChristopher E. Goldring; Giusy Russomanno; Carmen Pin; Panuwat Trairatphisan; Kylie A. Beattie; Ciarán P. Fisher; Janet Piñero; Richard J. Brennan; Diana Clausznitzer; Ian M. Copple; Theo M. de Kok; Carrie A. Duckworth; Laura I. Furlong; Barbara Füzi; Attila Gabor; Louis Gall; Jan Hengstler; Henning Hermjakob; Fiona Hunter; Danyel Jennen; Mikko Koskinen; Steven J. Kunnen; Lieve Lammens; Sebastian Lobentanzer; Marcel Mohr; Elisa Passini; D. Mark Pritchard; Rahuman S. Malik-Sheriff; Blanca Rodríguez; Eric I. Rossman; Julio Saez-Rodríguez; Friedemann Schmidt; Rowena Sison-Young; Inari Soininen; Sean Turner; Bob van de Water; Johan G. C. van Hasselt; Filippo Venezia; Jeffrey A. Willy; Derek J. Leishman; James L. Stevens; Loic Laplanche
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The importance of preclinical models in cholangiocarcinoma
errEJSO
IF2.9
err2025-02-01
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errOAAI
errMcgreevy, Owen; Bosakhar, Mohammed; Gilbert, Timothy; Quinn, Marc; Fenwick, Stephen; Malik, Hassan; Goldring, Christopher; Randle, Laura
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Molecular biology of cholangiocarcinoma and its implications for targeted therapy in patient management
errEJSO
IF2.9
err2025-02-01
err0
PREAI
errGilbert, T. M.; Randle, L.; Quinn, M.; Mcgreevy, O.; O'leary, L.; Young, R.; Diaz-Neito, R.; Jones, R. P.; Greenhalf, B.; Goldring, C.; Fenwick, S.; Malik, H.; Palmer, D. H.
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Response to Acetaminophen should be a critical reference hepatotoxin for evaluating human-relevant in vitro models
err2024-12-26
err0
PREAI
errLivoti, Lucia A.; Sison-Young, Rowena; Reddyhoff, Dennis; Fisher, Ciaran P.; Gardner, Iain; Diaz-Nieto, Rafael; Goldring, Christopher E.; Copple, Ian M.
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Construction and Expression of Fc-FGF21 by Different Expression Systems and Comparison of Their Similarity and Difference with Efruxifermin by In Vitro and In Vivo Studies
err2024-12-19
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errOAAI
errWang, Xujia; Meng, Qin; Jia, Aijuan; Zhou, Yuehua; Song, Dandan; Ma, Shaokang; Li, Wei; Zhang, Zhuobing; Goldring, Christopher; Feng, Hui; Wang, Mu
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Establishing reference ranges for circulating biomarkers of drug-induced liver injury in healthy human volunteers1
err2024-12-15
err0
errOAAI
errJorgensen, Andrea L.; Korver, Samantha; Schofield, Amy; Howell, Lawrence; Clarke, Joanna I.; Walker, Lauren E.; Brillant, Nathalie; Goldring, Chris E. P.; Pirmohamed, Munir
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Limitations of acetaminophen as a reference hepatotoxin for the evaluation of in vitro liver models
err2024-10-14
err2
errOAAI
errLivoti, Lucia A.; Sison-Young, Rowena; Reddyhoff, Dennis; Fisher, Ciaran P.; Gardner, Iain; Diaz-Nieto, Rafael; Goldring, Christopher E.; Copple, Ian M.
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A systems approach reveals species differences in hepatic stress response capacity
err2023-08-30
err4
errOAAI
errRussomanno, Giusy; Sison-Young, Rowena; Livoti, Lucia A.; Coghlan, Hannah; Jenkins, Rosalind E.; Kunnen, Steven J.; Fisher, Ciaran P.; Reddyhoff, Dennis; Gardner, Iain; Rehman, Adeeb H.; Fenwick, Stephen W.; Jones, Andrew R.; Vermeil De Conchard, Guy; Simonin, Gilles; Bertheux, Helene; Weaver, Richard J.; Johnson, Robert L.; Liguori, Michael J.; Clausznitzer, Diana; Stevens, James L.; Goldring, Christopher E.; Copple, Ian M.
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VEGF Stimulates Activation of ERK5 in the Absence of C-Terminal Phosphorylation Preventing Nuclear Localization and Facilitating AKT Activation in Endothelial Cells
errCELLS
IF5.2
err2023-03-22
err0
errOAAI
errMondru, Anil Kumar; Aljasir, Mohammad A.; Alrumayh, Ahmed; Nithianandarajah, Gopika N.; Ahmed, Katie; Muller, Jurgen; Goldring, Christopher E. P.; Wilm, Bettina; Cross, Michael J.
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Detection of Hepatic Drug Metabolite-Specific T-Cell Responses Using a Human Hepatocyte, Immune Cell Coculture System
err2023-02-22
err5
errOAAI
errAli, Serat-E; Meng, Xiaoli; Kafu, Laila; Hammond, Sean; Zhao, Qing; Ogese, Monday; Sison-Young, Rowena; Jones, Robert; Chan, Benjamin; Livoti, Lucia; Sun, Yonghu; Sun, Lele; Liu, Hong; Topping, Anthony; Goldring, Christopher; Zhang, Furen; Naisbitt, Dean John
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Identification of flucloxacillin-modified hepatocellular proteins: implications in flucloxacillin-induced liver injury
err2023-02-14
err6
errOAAI
errAli, Serat-E; Waddington, James C.; Lister, Adam; Sison-Young, Rowena; Jones, Robert P.; Rehman, Adeeb H.; Goldring, Chris E. P.; Naisbitt, Dean J.; Meng, Xiaoli
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Analysis of serum microRNA-122 in a randomized controlled trial of N-acetylcysteine for treatment of antituberculosis drug-induced liver injury
err2023-01-29
err6
errOAAI
errMoosa, Muhammed Shiraz; Russomanno, Giusy; Dorfman, Jeffrey R.; Gunter, Hannah; Patel, Chandni; Costello, Eithne; Carr, Dan; Maartens, Gary; Pirmohamed, Munir; Goldring, Christopher; Cohen, Karen
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Developing a patient-derived model of cholangiocarcinoma using Precision Cut Tissue Slices (PCTS)
err2022-12-07
err0
PREAI
errGilbert, Timothy; Randle, Laura; Diaz-Nieto, Rafael; Jones, Robert; Fenwick, Stephen; Goldring, Christopher; Malik, Hassan
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Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity
err2022-07-01
err45
errOAAI
errGhallab, Ahmed; Hassan, Reham; Hofmann, Ute; Friebel, Adrian; Hobloss, Zaynab; Brackhagen, Lisa; Begher-Tibbe, Brigitte; Myllys, Maiju; Reinders, Joerg; Overbeck, Nina; Sezgin, Selahaddin; Zuehlke, Sebastian; Seddek, Abdel-Latif; Murad, Walaa; Brecklinghaus, Tim; Kappenberg, Franziska; Rahnenfuehrer, Joerg; Gonzalez, Daniela; Goldring, Christopher; Copple, Ian M.; Marchan, Rosemarie; Longerich, Thomas; Vucur, Mihael; Luedde, Tom; Urban, Stephan; Canbay, Ali; Schreiter, Thomas; Trauner, Michael; Akakpo, Jephte Y.; Olyaee, Mojtaba; Curry, Steven C.; Sowa, Jan-Peter; Jaeschke, Hartmut; Hoehme, Stefan; Hengstler, Jan G.
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The application of cytokeratin-18 as a biomarker for drug-induced liver injury
err2021-07-29
err29
errOAAI
errKorver, Samantha; Bowen, Joanne; Pearson, Kara; Gonzalez, Raymond J.; French, Neil; Park, Kevin; Jenkins, Rosalind; Goldring, Christopher
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Pharmacological Activation of Nrf2 Enhances Functional Liver Regeneration
err2021-07-13
err35
errOAAI
errChan, Benjamin K. Y.; Elmasry, Mohamed; Forootan, Shiva S.; Russomanno, Giusy; Bunday, Tobias M.; Zhang, Fang; Brillant, Nathalie; Lewis, Philip J. Starkey; Aird, Rhona; Ricci, Emanuele; Andrews, Timothy D.; Sison-Young, Rowena L.; Schofield, Amy L.; Fang, Yongxiang; Lister, Adam; Sharkey, Jack W.; Poptani, Harish; Kitteringham, Neil R.; Forbes, Stuart J.; Malik, Hassan Z.; Fenwick, Stephen W.; Park, B. Kevin; Goldring, Christopher E.; Copple, Ian M.
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Gene Signatures Reduce the Stress of Preclinical Drug Hepatotoxicity Screening
err2021-06-18
err3
errOAAI
errCopple, Ian M.; Park, B. Kevin; Goldring, Christopher E.
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Proteomic profiling of murine biliary-derived hepatic organoids and their capacity for drug disposition, bioactivation and detoxification
err2021-05-29
err2
errOAAI
errHowell, Lawrence; Jenkins, Rosalind E.; Lynch, Stephen; Duckworth, Carrie; Kevin Park, B.; Goldring, Christopher
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Safety perspectives on presently considered drugs for the treatment of COVID-19
err2020-08-13
err15
errOAAI
errPenman, Sophie L.; Kiy, Robyn T.; Jensen, Rebecca L.; Beoku-Betts, Christopher; Alfirevic, Ana; Back, David; Khoo, Saye H.; Owen, Andrew; Pirmohamed, Munir; Park, B. Kevin; Meng, Xiaoli; Goldring, Christopher E.; Chadwick, Amy E.
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