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L

Lloyd W. Ruddock

faculty of biochemistry and molecular medicine

45H-index
158Paper Count
7.6KCitation Count
Published Papers 76
Publication Date
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Proline iminopeptidase: a novel in vivo strategy to produce proteins with homogeneous and authentic N-termini in E. coli
errMicrobial Cell Factories
IF4.9
err2026-08-04
err0
errOAAI
errThu Pham Anh Nguyen; Zinke Vanderdeelen; Lukas Rettenbacher; Mirva J. Saaranen; Lloyd W. Ruddock
errShare
errSave
Crystal Structure of Candida antarctica Lipase B with a Putative Pro-Peptide Region
errCRYSTALS
IF2.4
err2025-10-28
err0
errOAAI
errSohail, Anil A.; Recacha, Rosario; Ruddock, Lloyd W.
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errSave
Expression of amyotrophic lateral sclerosis associated protein disulfide isomerase A3 D217N variant recapitulates early morphological alterations at the neuromuscular junction
errNeurobiology of Disease
IF5.6
err2025-08-05
err0
errOAAI
errMartin Sepulveda; Francisca MartinezTraub; Patricia Ojeda; Jessica Mella; Jorge Ojeda; Cristina Pinto; Rodrigo Diaz; Pablo Rozas; Claudia Sepulveda; Bredford Kerr; Vania Morales; Mirva Saaranen; Lloyd Ruddock; Danilo B. Medinas; Juan Pablo Henriquez; Claudio Hetz
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errSave
Structural insights on perlecan and Schwartz-Jampel syndrome
errMATRIX BIOLOGY
IF4.8
err2025-06-01
err0
PREAI
errSohail, Anil A.; Koski, M. Kristian; Ruddock, Lloyd W.
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errSave
Toward Antibody Production in Genome-Minimized Bacillus subtilis Strains
errACS SYNTHETIC BIOLOGY
IF3.9
err2025-02-27
err0
errOAAI
errSchilling, Tobias; Biedendieck, Rebekka; Moran-Torres, Rafael; Saaranen, Mirva J.; Ruddock, Lloyd W.; Daniel, Rolf; van Dijl, Jan Maarten
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errSave
Biophysical and structural studies of fibulin-2
errSCIENTIFIC REPORTS
IF3.9
err2024-07-02
err0
errOAAI
errSohail, Anil A.; Koski, M. Kristian; Ruddock, Lloyd W.
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errSave
Bulky Hydrophobic Side Chains In The β1-sandwich Of Microsomal Triglyceride Transfer Protein Are Critical For The Transfer Of Both Triglycerides And Phospholipids
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2024-05-01
err0
PREAI
errAnaganti, Narasimha; Valmiki, Swati; Recacha, Rosario; Islam, Shahidul; Farber, Steven; Ruddock, Lloyd; Hussain, M. M.
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errSave
Komagataella phaffii Erp41 is a protein disulfide isomerase with unprecedented disulfide bond catalyzing activity when coupled to glutathione
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err1
errOAAI
errPalma, Arianna; Rettenbacher, Lukas A.; Moilanen, Antti; Saaranen, Mirva; Gasser, Brigitte; Ruddock, Lloyd W.
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errSave
Bulky hydrophobic side chains in the β1-sandwich of microsomal triglyceride transfer protein are critical for the transfer of both triglycerides and phospholipids
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err2
errOAAI
errAnaganti, Narasimha; Valmiki, Swati; Recacha, Rosario; Islam, Shahidul; Farber, Steven; Ruddock, Lloyd; Hussain, M. Mahmood
errShare
errSave
Biochemical analysis of Komagataella phaffii oxidative folding proposes novel regulatory mechanisms of disulfide bond formation in yeast
errSCIENTIFIC REPORTS
IF3.9
err2023-08-31
err3
errOAAI
errPalma, Arianna; Rettenbacher, Lukas A.; Moilanen, Antti; Saaranen, Mirva; Pacheco-Martinez, Christian; Gasser, Brigitte; Ruddock, Lloyd
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errSave
Design of an alternate antibody fragment format that can be produced in the cytoplasm of Escherichia coli
errSCIENTIFIC REPORTS
IF3.9
err2023-08-30
err2
errOAAI
errTungekar, Aatir A.; Ruddock, Lloyd W.
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errSave
Mechanistic insights into the ROS-mediated inactivation of human aldehyde oxidase
errFEBS LETTERS
IF3
err2023-06-03
err0
PREAI
errEsmaeeli, Mariam; Nimtz, Manfred; Jaensch, Lothar; Ruddock, Lloyd W.; Leimkuehler, Silke
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errSave
Production of neutralizing antibody fragment variants in the cytoplasm of E. coli for rapid screening: SARS-CoV-2 a case study
errSCIENTIFIC REPORTS
IF3.9
err2023-03-16
err6
errOAAI
errTungekar, Aatir A.; Recacha, Rosario; Ruddock, Lloyd W.
errShare
errSave
Highly efficient export of a disulfide-bonded protein to the periplasm and medium by the Tat pathway using CyDisCo in Escherichia coli
errMICROBIOLOGYOPEN
IF4.6
err2023-03-08
err6
errOAAI
errArauzo-Aguilera, Klaudia; Saaranen, Mirva J.; Robinson, Colin; Ruddock, Lloyd W.
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errSave
Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H α2β2 tetramer
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-12-01
err7
errOAAI
errMurthy, Abhinandan V.; Sulu, Ramita; Lebedev, Andrey; Salo, Antti M.; Korhonen, Kati; Venkatesan, Rajaram; Tu, Hongmin; Bergmann, Ulrich; Janis, Janne; Laitaoja, Mikko; Ruddock, Lloyd W.; Myllyharju, Johanna; Koski, M. Kristian; Wierenga, Rik K.
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errSave
Introduction of a More Glutaredoxin-like Active Site to PDI Results in Competition between Protein Substrate and Glutathione Binding
errANTIOXIDANTS
IF6.6
err2022-09-28
err4
errOAAI
errSaaranen, Mirva J.; Alanen, Heli, I; Salo, Kirsi E. H.; Nji, Emmanuel; Karkkainen, Pekka; Schmotz, Constanze; Ruddock, Lloyd W.
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errSave
Microbial protein cell factories fight back?
errTRENDS IN BIOTECHNOLOGY
IF14.9
err2022-05-01
err28
errOAAI
errRettenbacher, Lukas A.; Arauzo-Aguilera, Klaudia; Buscajoni, Luisa; Castillo-Corujo, Angel; Ferrero-Bordera, Borja; Kostopoulou, Aliki; Moran-Torres, Rafael; Nunez-Nepomuceno, David; OEktem, Ayseguel; Palma, Arianna; Pisent, Beatrice; Puricelli, Martina; Schilling, Tobias; Tungekar, Aatir A.; Walgraeve, Jonathan; Humphreys, David; Haar, Tobias von der; Gasser, Brigitte; Mattanovich, Diethard; Ruddock, Lloyd; Dijl, Jan Maarten van
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Mutation in protein disulfide isomerase A3 causes neurodevelopmental defects by disturbing endoplasmic reticulum proteostasis
errEMBO JOURNAL
IF8.3
err2021-12-14
err17
errOAAI
errMedinas, Danilo Bilches; Malik, Sajid; Yildiz-Bolukbasi, Esra; Borgonovo, Janina; Saaranen, Mirva J.; Urra, Hery; Pulgar, Eduardo; Afzal, Muhammad; Contreras, Darwin; Wright, Madison T.; Bodaleo, Felipe; Quiroz, Gabriel; Rozas, Pablo; Mumtaz, Sara; Diaz, Rodrigo; Rozas, Carlos; Cabral-Miranda, Felipe; Pina, Ricardo; Valenzuela, Vicente; Uyan, Ozgun; Reardon, Christopher; Woehlbier, Ute; Brown, Robert H.; Sena-Esteves, Miguel; Gonzalez-Billault, Christian; Morales, Bernardo; Plate, Lars; Ruddock, Lloyd W.; Concha, Miguel L.; Hetz, Claudio; Tolun, Aslihan
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So you want to express your protein in Escherichia coli?
errMICROBIAL CELL FACTORIES-BOOK
IF0
err2021-07-26
err18
errOAAI
errTungekar, Aatir A.; Castillo-Corujo, Angel; Ruddock, Lloyd W.
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errSave
The Amino-Terminal Oligomerization Domain of Angiopoietin-2 Affects Vascular Remodeling, Mammary for Gland Tumor Growth, and Lung Metastasis in Mice
errCANCER RESEARCH
IF16.6
err2021-01-04
err6
errOAAI
errKapiainen, Emmi; Kihlstrom, Minna K.; Pietila, Riikka; Kaakinen, Mika; Ronkainen, Veli-Pekka; Tu, Hongmin; Heikkinen, Anne; Devarajan, Raman; Miinalainen, Ilkka; Laitakari, Anna; Ansarizadeh, Mohammadhassan; Zhang, Qin; Wei, Gong-Hong; Ruddock, Lloyd; Pihlajaniemi, Taina; Elamaa, Harri; Eklund, Lauri
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
R
Robert H. Brown
H-index: 123 · Papers: 513
N
Nigel Mackman
H-index: 122 · Papers: 828
S
Steffen Maßberg
H-index: 100 · Papers: 819
J
Jacek Majewski
H-index: 93 · Papers: 458
C
Claudio Hetz
H-index: 89 · Papers: 313
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