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Expression of protein disulfide isomerase A3Q481K variant associated with amyotrophic lateral sclerosis triggers disease features in mice Sepulveda, Martin; Traub, Francisca Martinez; Ojeda, Patricia; Perez, Viviana; Ojeda, Jorge; Mella, Jessica; Diaz, Rodrigo; Rozas, Pablo; Mansilla-Jaramillo, Matias; Zuleta, Amparo; Diaz, Guillermo; Kerr, Bredford; Woehlbier, Ute; Henriquez, Juan Pablo; Medinas, Danilo B.; Hetz, Claudio Share Save
Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons (vol 41, pg 209, 2011) Klein, Andres; Maldonado, Carola; Vargas, Lina M.; Gonzalez, Marcela; Robledo, Fermin; de Arce, Karen Perez; Munoz, Francisco J.; Hetz, Claudio; Alvarez, Alejandra R.; Zanlungo, Silvana Share Save
Artificial enforcement of the unfolded protein response reduces disease features in multiple preclinical models of ALS/FTD Valenzuela, Vicente; Becerra, Daniela; Astorga, Jose I.; Fuentealba, Matias; Diaz, Guillermo; Bargsted, Leslie; Chacon, Carlos; Martinez, Alexis; Gozalvo, Romina; Jackson, Kasey; Morales, Vania; Heras, Macarena Las; Tamburini, Giovanni; Petrucelli, Leonard; Sardi, S. Pablo; Plate, Lars; Hetz, Claudio Share Save
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IRE1α Mediates the Hypertrophic Growth of Cardiomyocytes Through Facilitating the Formation of Initiation Complex to Promote the Translation of TOP-Motif Transcripts Li, Chao; Li, Shiqian; Zhang, Guangyu; Li, Qinfeng; Song, Weidan; Wang, Xiaoding; Cook, Jane A.; van der Stoel, Miesje; Wright, Bradley W.; Altamirano, Francisco; Niewold, Erica L.; Han, Jungsoo; Kimble, Garrett; Zhang, Pengfei; Luo, Xiang; Urra, Hery; May, Herman I.; Ferdous, Anwarul; Sun, Xue-Nan; Deng, Yingfeng; Ikonen, Elina; Hetz, Claudio; Kaufman, Randal J.; Zhang, Kezhong; Gillette, Thomas G.; Scherer, Philipp E.; Hill, Joseph A.; Chen, Jin; Wang, Zhao V. Share Save
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IGF2 prevents dopaminergic neuronal loss and decreases intracellular alpha-synuclein accumulation in Parkinson's disease models Arcos, Javiera; Grunenwald, Felipe; Sepulveda, Denisse; Jerez, Carolina; Urbina, Valentina; Huerta, Tomas; Troncoso-Escudero, Paulina; Tirado, Daniel; Perez, Angela; Diaz-Espinoza, Rodrigo; Nova, Esteban; Kubitscheck, Ulrich; Rodriguez-Gatica, Juan Eduardo; Hetz, Claudio; Toledo, Jorge; Ahumada, Pablo; Rojas-Rivera, Diego; Martin-Montanez, Elisa; Garcia-Fernandez, Maria; Vidal, Rene L. Share Save
The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation Carreras-Sureda, Amado; Zhang, Xin; Laubry, Loann; Brunetti, Jessica; Koenig, Stephane; Wang, Xiaoxia; Castelbou, Cyril; Hetz, Claudio; Liu, Yong; Frieden, Maud; Demaurex, Nicolas Share Save
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c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration Martinez, Alexis; Lamaizon, Cristian M.; Valls, Cristian; Llambi, Fabien; Leal, Nancy; Fitzgerald, Patrick; Guy, Cliff; Kaminski, Marcin M.; Inestrosa, Nibaldo C.; van Zundert, Brigitte; Cancino, Gonzalo I.; Dulcey, Andres E.; Zanlungo, Silvana; Marugan, Juan J.; Hetz, Claudio; Green, Douglas R.; Alvarez, Alejandra R. Share Save
Generation of Genetically Modified Mouse Models to Study Protein Disulfide Isomerase A3 Involvement in Neurological Disorders Medinas, Danilo; Rozas, Pablo; Baker, Harrison; Ferreira, Julio Cesar; Teramayi, Fadzai; Ojeda-Provoste, Patricia; Espinosa, Giselle; Quiroz, Gabriel; Pestana, Ricardo; Melleu, Fernando; Contreras, Darwin; Godoy, Felipe; Rozas, Carlos; Motta, Simone; Mochly-Rosen, Daria; Canteras, Newton; Ellerby, Lisa; Hetz, Claudio Share Save
The unfolded protein response transcription factor XBP1s ameliorates Alzheimer's disease by improving synaptic function and proteostasis Duran-Aniotz, Claudia; Poblete, Natalia; Rivera-Krstulovic, Catalina; Ardiles, alvaro O.; Li Diaz-Hung, Mei; Tamburini, Giovanni; Sabusap, Carleen Mae P.; Gerakis, Yannis; Cabral-Miranda, Felipe; Diaz, Javier; Fuentealba, Matias; Arriagada, Diego; Munoz, Ernesto; Espinoza, Sandra; Martinez, Gabriela; Quiroz, Gabriel; Sardi, Pablo; Medinas, Danilo B.; Contreras, Darwin; Pina, Ricardo; V. Lourenco, Mychael; Ribeiro, Felipe C.; Ferreira, Sergio T.; Rozas, Carlos; Morales, Bernardo; Plate, Lars; Gonzalez-Billault, Christian; Palacios, Adrian G.; Hetz, Claudio Share Save
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Proteomic Analysis of Huntington's Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets Tshilenge, Kizito-Tshitoko; Aguirre, Carlos Galicia; Bons, Joanna; Gerencser, Akos A.; Basisty, Nathan; Song, Sicheng; Rose, Jacob; Lopez-Ramirez, Alejandro; Naphade, Swati; Loureiro, Ashley; Battistoni, Elena; Milani, Mateus; Wehrfritz, Cameron; Holtz, Anja; Hetz, Claudio; Mooney, Sean D.; Schilling, Birgit; Ellerby, Lisa M. Share Save
Apoptotic cell death in disease-Current understanding of the NCCD 2023 Vitale, Ilio; Pietrocola, Federico; Guilbaud, Emma; Aaronson, Stuart A.; Abrams, John M.; Adam, Dieter; Agostini, Massimiliano; Agostinis, Patrizia; Alnemri, Emad S.; Altucci, Lucia; Amelio, Ivano; Andrews, David W.; Aqeilan, Rami, I; Arama, Eli; Baehrecke, Eric H.; Balachandran, Siddharth; Bano, Daniele; Barlev, Nickolai A.; Bartek, Jiri; Bazan, Nicolas G.; Becker, Christoph; Bernassola, Francesca; Bertrand, Mathieu J. M.; Bianchi, Marco E.; Blagosklonny, Mikhail V.; Blander, J. Magarian; Blandino, Giovanni; Blomgren, Klas; Borner, Christoph; Bortner, Carl D.; Bove, Pierluigi; Boya, Patricia; Brenner, Catherine; Broz, Petr; Brunner, Thomas; Damgaard, Rune Busk; Calin, George A.; Campanella, Michelangelo; Candi, Eleonora; Carbone, Michele; Carmona-Gutierrez, Didac; Cecconi, Francesco; Chan, Francis K-M; Chen, Guo-Qiang; Chen, Quan; Chen, Youhai H.; Cheng, Emily H.; Chipuk, Jerry E.; Cidlowski, John A.; Ciechanover, Aaron; Ciliberto, Gennaro; Conrad, Marcus; Cubillos-Ruiz, Juan R.; Czabotar, Peter E.; D'Angiolella, Vincenzo; Daugaard, Mads; Dawson, Ted M.; Dawson, Valina L.; De Maria, Ruggero; De Strooper, Bart; Debatin, Klaus-Michael; Deberardinis, Ralph J.; Degterev, Alexei; Del Sal, Giannino; Deshmukh, Mohanish; Di Virgilio, Francesco; Diederich, Marc; Dixon, Scott J.; Dynlacht, Brian D.; El-Deiry, Wafik S.; Elrod, John W.; Engeland, Kurt; Fimia, Gian Maria; Galassi, Claudia; Ganini, Carlo; Garcia-Saez, Ana J.; Garg, Abhishek D.; Garrido, Carmen; Gavathiotis, Evripidis; Gerlic, Motti; Ghosh, Sourav; Green, Douglas R.; Greene, Lloyd A.; Gronemeyer, Hinrich; Haecker, Georg; Hajnoczky, Gyorgy; Hardwick, J. Marie; Haupt, Ygal; He, Sudan; Heery, David M.; Hengartner, Michael O.; Hetz, Claudio; Hildeman, David A.; Ichijo, Hidenori; Inoue, Satoshi; Jaeaettelae, Marja; Janic, Ana; Joseph, Bertrand; Jost, Philipp J.; Kanneganti, Thirumala-Devi; Karin, Michael; Kashkar, Hamid; Kaufmann, Thomas; Kelly, Gemma L.; Kepp, Oliver; Kimchi, Adi; Kitsis, Richard N.; Klionsky, Daniel J.; Kluck, Ruth; Krysko, Dmitri, V; Kulms, Dagmar; Kumar, Sharad; Lavandero, Sergio; Lavrik, Inna N.; Lemasters, John J.; Liccardi, Gianmaria; Linkermann, Andreas; Lipton, Stuart A.; Lockshin, Richard A.; Lopez-Otin, Carlos; Luedde, Tom; MacFarlane, Marion; Madeo, Frank; Malorni, Walter; Manic, Gwenola; Mantovani, Roberto; Marchi, Saverio; Marine, Jean-Christophe; Martin, Seamus J.; Martinou, Jean-Claude; Mastroberardino, Pier G.; Medema, Jan Paul; Mehlen, Patrick; Meier, Pascal; Melino, Gerry; Melino, Sonia; Miao, Edward A.; Moll, Ute M.; Munoz-Pinedo, Cristina; Murphy, Daniel J.; Niklison-Chirou, Maria Victoria; Novelli, Flavia; Nunez, Gabriel; Oberst, Andrew; Ofengeim, Dimitry; Opferman, Joseph T.; Oren, Moshe; Pagano, Michele; Panaretakis, Theocharis; Pasparakis, Manolis; Penninger, Josef M.; Pentimalli, Francesca; Pereira, David M.; Pervaiz, Shazib; Peter, Marcus E.; Pinton, Paolo; Porta, Giovanni; Prehn, Jochen H. M.; Puthalakath, Hamsa; Rabinovich, Gabriel A.; Rajalingam, Krishnaraj; Ravichandran, Kodi S.; Rehm, Markus; Ricci, Jean-Ehrland; Rizzuto, Rosario; Robinson, Nirmal; Rodrigues, Cecilia M. P.; Rotblat, Barak; Rothlin, Carla, V; Rubinsztein, David C.; Rudel, Thomas; Rufini, Alessandro; Ryan, Kevin M.; Sarosiek, Kristopher A.; Sawa, Akira; Sayan, Emre; Schroder, Kate; Scorrano, Luca; Sesti, Federico; Shao, Feng; Shi, Yufang; Sica, Giuseppe S.; Silke, John; Simon, Hans-Uwe; Sistigu, Antonella; Stephanou, Anastasis; Stockwell, Brent R.; Strapazzon, Flavie; Strasser, Andreas; Sun, Liming; Sun, Erwei; Sun, Qiang; Szabadkai, Gyorgy; Tait, Stephen W. G.; Tang, Daolin; Tavernarakis, Nektarios; Troy, Carol M.; Turk, Boris; Urbano, Nicoletta; Vandenabeele, Peter; Vanden Berghe, Tom; Vander Heiden, Matthew G.; Vanderluit, Jacqueline L.; Verkhratsky, Alexei; Villunger, Andreas; von Karstedt, Silvia; Voss, Anne K.; Vousden, Karen H.; Vucic, Domagoj; Vuri, Daniela; Wagner, Erwin F.; Walczak, Henning; Wallach, David; Wang, Ruoning; Wang, Ying; Weber, Achim; Wood, Will; Yamazaki, Takahiro; Yang, Huang-Tian; Zakeri, Zahra; Zawacka-Pankau, Joanna E.; Zhang, Lin; Zhang, Haibing; Zhivotovsky, Boris; Zhou, Wenzhao; Piacentini, Mauro; Kroemer, Guido; Galluzzi, Lorenzo Share Save
Dual IRE1 RNase functions dictate glioblastoma development (vol 10, e7929, 2018) Lhomond, Stephanie; Avril, Tony; Dejeans, Nicolas; Voutetakis, Konstantinos; Doultsinos, Dimitrios; McMahon, Mari; Pineau, Raphael; Obacz, Joanna; Papadodima, Olga; Jouan, Florence; Bourien, Heloise; Logotheti, Marianthi; Jegou, Gwenaele; Pallares-Lupon, Nestor; Schmit, Kathleen; Le Reste, Pierre-Jean; Etcheverry, Amandine; Mosser, Jean; Barroso, Kim; Vauleon, Elodie; Maurel, Marion; Samali, Afshin; Patterson, John B.; Pluquet, Olivier; Hetz, Claudio; Quillien, Veronique; Chatziioannou, Aristotelis; Chevet, Eric Share Save
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