Not logged in Pharmacologic LDH inhibition redirects intratumoral glucose uptake and improves antitumor immunity in solid tumor models Verma, Svena; Budhu, Sadna; Serganova, Inna; Dong, Lauren; Mangarin, Levi M.; Khan, Jonathan F.; Bah, Mamadou A.; Assouvie, Anais; Marouf, Yacine; Schulze, Isabell; Zappasodi, Roberta; Wolchok, Jedd D.; Merghoub, Taha Share Save
Melanoma-intrinsic expression of signal-regulatory protein alpha (SIRPα) confers tumor cells resistance to anti-tumor adaptive immunity Weng, Chien-Huan; Schochet, Chana; Hamadene, Linda; Eghbali, Shabnam; Monette, Sebastien; Mangarin, Levi; Liu, Cailian; Samaan, Fadi; Wolchok, Jedd D.; Merghoub, Taha Share Save
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Gut microbiota mimics as a source of cross-reactive tumor rejection antigens Panneton, Vincent; Gigoux, Mathieu; Zebboudj, Abderezak; Sadek, Norah; Choi, Hyejin; Mangarin, Levi M.; George, Mariam M.; Kulakowski, Guillaume; Magalhaes, Joao G.; Carpier, Jean-Marie; Dugat, Thibaud; Gaal, Camille; Strozzi, Francesco; Tibaldi, Lorenzo; Chene, Laurent; Wolchok, Jedd D.; Balachandran, Vinod P.; Merghoub, Taha Share Save
Neutrophil recruitment and activation promotes cutaneous adverse effects with T cell immunotherapies Hirschhorn, Daniel; Kraehenbuehl, Lukas; Budhu, Sadna; Navarro, Valeria Estrada; Mangarin, Levi Mark B.; Marouf, Yacine; Ricca, Jacob; Gasmi, Billel; De Henau, Olivier; Li, Yanyun; Cortez, Czrina; Linda, Hamadene; Schulze, Isabell; Liu, Cailian; Panageas, Katherine; Lacuoture, Mario; Rizzuto, Gabrielle A.; Egeblad, Mikala; Wolchok, Jedd D.; Merghoub, Taha Merghoub Share Save
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The ectonucleotidase CD39 identifies tumor-reactive CD8+T cells predictive of immune checkpoint blockade efficacy in human lung cancer Chow, Andrew; Uddin, Fathema Z.; Liu, Michael; Dobrin, Anton; Nabet, Barzin Y.; Mangarin, Levi; Lavin, Yonit; Rizvi, Hira; Tischfield, Sam E.; Quintanal-Villalonga, Alvaro; Chan, Joseph M.; Shah, Nisargbhai; Allaj, Viola; Manoj, Parvathy; Mattar, Marissa; Meneses, Maximiliano; Landau, Rebecca; Ward, Mariana; Kulick, Amanda; Kwong, Charlene; Wierzbicki, Matthew; Yavner, Jessica; Egger, Jacklynn; Chavan, Shweta S.; Farillas, Abigail; Holland, Aliya; Sridhar, Harsha; Ciampricotti, Metamia; Hirschhorn, Daniel; Guan, Xiangnan; Richards, Allison L.; Heller, Glenn; Mansilla-Soto, Jorge; Sadelain, Michel; Klebanoff, Christopher A.; Hellmann, Matthew D.; Sen, Triparna; de Stanchina, Elisa; Wolchok, Jedd D.; Merghoub, Taha; Rudin, Charles M. Share Save
SIGNAL-REGULATORY PROTEIN ALPHA (SIRPα) CONFERS TUMOR CELL RESISTANCE TO ANTI-TUMOR IMMUNITY Weng, Chien-Huan; Hamadene, Linda; Eghbali, Shabnam; Venkatesh, Divya; Monette, Sebastien; Mangarin, Levi; Samaan, Fadi; Liu, Cailian; Holland, Pamela; Wolchok, Jedd; Merghoub, Taha Share Save
Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade Ghosh, Arnab; Michels, Judith; Mezzadra, Riccardo; Venkatesh, Divya; Dong, Lauren; Gomez, Ricardo; Samaan, Fadi; Ho, Yu-Jui; Campesato, Luis Felipe; Mangarin, Levi; Fak, John; Suek, Nathan; Holland, Aliya; Liu, Cailian; Abu-Akeel, Mohsen; Bykov, Yonina; Zhong, Hong; Fitzgerald, Kelly; Budhu, Sadna; Chow, Andrew; Zappasodi, Roberta; Panageas, Katherine S.; de Henau, Olivier; Ruscetti, Marcus; Lowe, Scott W.; Merghoub, Taha; Wolchok, Jedd D. Share Save
Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine Gigoux, Mathieu; Holmstrom, Morten O.; Zappasodi, Roberta; Park, Joseph J.; Pourpe, Stephane; Bozkus, Cansu Cimen; Mangarin, Levi M. B.; Redmond, David; Verma, Svena; Schad, Sara; George, Mariam M.; Venkatesh, Divya; Ghosh, Arnab; Hoyos, David; Molvi, Zaki; Kamaz, Baransel; Marneth, Anna E.; Duke, William; Leventhal, Matthew J.; Jan, Max; Ho, Vincent T.; Hobbs, Gabriela S.; Knudsen, Trine Alma; Skov, Vibe; Kjaer, Lasse; Larsen, Thomas Stauffer; Hansen, Dennis Lund; Lindsley, R. Coleman; Hasselbalch, Hans; Grauslund, Jacob H.; Lisle, Thomas L.; Met, Ozcan; Wilkinson, Patrick; Greenbaum, Benjamin; Sepulveda, Manuel A.; Chan, Timothy; Rampal, Raajit; Andersen, Mads H.; Abdel-Wahab, Omar; Bhardwaj, Nina; Wolchok, Jedd D.; Mullally, Ann; Merghoub, Taha Share Save
Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions Schad, Sara E.; Chow, Andrew; Mangarin, Levi; Pan, Heng; Zhang, Jiajia; Ceglia, Nicholas; Caushi, Justina X.; Malandro, Nicole; Zappasodi, Roberta; Gigoux, Mathieu; Hirschhorn, Daniel; Budhu, Sadna; Amisaki, Masataka; Arniella, Monica; Redmond, David; Chaft, Jamie; Forde, Patrick M.; Gainor, Justin F.; Hellmann, Matthew D.; Balachandran, Vinod; Shah, Sohrab; Smith, Kellie N.; Pardoll, Drew; Elemento, Olivier; Wolchok, Jedd D.; Merghoub, Taha Share Save
Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness Hirschhorn, Daniel; Warner, Allison Betof; Maniyar, Rachana; Chow, Andrew; Mangarin, Levi Mb; Cohen, Adam D.; Hamadene, Linda; Rizzuto, Gabrielle A.; Budhu, Sadna; Suek, Nathan; Liu, Cailian; Houghton, Alan N.; Merghoub, Taha; Wolchok, Jedd D. Share Save
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CHARACTERIZING DOUBLE POSITIVE T CELLS IN THE TUMOR MICROENVIRONMENT: A TALE OF PROMISCUOUS CELL FATES Schad, Sara; Chow, Andrew; Pan, Heng; Mangarin, Levi; Zappasodi, Roberta; Gigoux, Mathieu; Redmond, David; Hirschhorn-Cymerman, Daniel; Budhu, Sadna; Zhong, Hong; Yang, Xia; Elemento, Olivier; Wolchok, Jedd; Merghoub, Taha Share Save
MHC-I SKEWING IN MUTANT CALRETICULIN-POSITIVE MYELOPROLIFERATIVE NEOPLASMS IS COUNTERED BY HETEROCLITIC PEPTIDE CANCER VACCINATION Gigoux, Mathieu; Zappasodi, Roberta; Park, Joseph; Pourpe, Stephane; Ghosh, Arnab; Bozkus, Cansu Cimen; Mangarin, Levi; Redmond, David; Verma, Svena; Schad, Sara; Duke, William; Jan, Max; Leventhal, Matthew; Ho, Vincent; Hobbs, Gabriela; Knudsen, Trine Alma; Skov, Vibe; Kjaer, Lasse; Larsen, Thomas Stauffer; Hansen, Dennis Lund; Lindsley, R. Coleman; Hasselbalch, Hans; Grauslund, Jacob; Andersen, Mads; Holmstrom, Morten; Chan, Timothy; Rampal, Raajit; Abdel-Wahab, Omar; Bhardwaj, Nina; Wolchok, Jedd; Mullally, Ann; Merghoub, Taha Share Save
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine Campesato, Luis Felipe; Budhu, Sadna; Tchaicha, Jeremy; Weng, Chien-Huan; Gigoux, Mathieu; Cohen, Ivan Jose; Redmond, David; Mangarin, Levi; Pourpe, Stephane; Liu, Cailian; Zappasodi, Roberta; Zamarin, Dmitriy; Cavanaugh, Jill; Castro, Alfredo C.; Manfredi, Mark G.; McGovern, Karen; Merghoub, Taha; Wolchok, Jedd D. Share Save
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