Not logged in The TDP-43I383V heterozygous mutation results in increased TDP-43 expression and altered neuronal activity in ALS patient-derived iPSC motor neurons Chikuchi, Ryo; Kato, Yuta; Tomatsu, Aya; Nishisaki, Shuto; Kawakami, Yu; Yoshimura, Takashi; Li, Jiayi; Iguchi, Yohei; Onodera, Kazunari; Hashimoto, Rina; Aiba, Ikuko; Nakamura, Ryoichi; Tohnai, Genki; Atsuta, Naoki; Sobue, Gen; Okada, Yohei; Katsuno, Masahisa; Yokoi, Satoshi Share Save
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Regional health priorities for dementia: a roadmap for the Western Pacific Timmins, Hannah C.; Mok, Vincent C. T.; Kim, Seung Hyun; Shahrizaila, Nortina; Sung, Jia-Ying; Sobue, Gen; Agustini, Sheila; Ward, Stephanie; Anstey, Kaarin J.; Talbot, Dayna-Lee; Mazumder, Srestha; Tu, Sicong; Tan, Rachel H.; Lin, Cindy Shin-Yi; Callaghan, Claire O. '; Michaelian, Johannes C.; Jeon, Yun-Hee; Foxe, David; Naismith, Sharon L.; Piguet, Olivier; Ahmed, Rebekah; Devenney, Emma; Park, Susanna B.; Kiernan, Matthew C. Share Save
CHCHD2 P14L, found in amyotrophic lateral sclerosis, exhibits cytoplasmic mislocalization and alters Ca2+ homeostasis Ikeda, Aya; Meng, Hongrui; Taniguchi, Daisuke; Mio, Muneyo; Funayama, Manabu; Nishioka, Kenya; Yoshida, Mari; Li, Yuanzhe; Yoshino, Hiroyo; Inoshita, Tsuyoshi; Shiba-Fukushima, Kahori; Okubo, Yohei; Sakurai, Takashi; Amo, Taku; Aiba, Ikuko; Saito, Yufuko; Saito, Yuko; Murayama, Shigeo; Atsuta, Naoki; Nakamura, Ryoichi; Tohnai, Genki; Izumi, Yuishin; Morita, Mitsuya; Tamura, Asako; Kano, Osamu; Oda, Masaya; Kuwabara, Satoshi; Yamashita, Toru; Sone, Jun; Kaji, Ryuji; Sobue, Gen; Imai, Yuzuru; Hattori, Nobutaka Share Save
Stress-impaired reward pathway promotes distinct feeding behavior patterns Fujioka, Yusuke; Kawai, Kaori; Endo, Kuniyuki; Ishibashi, Minaka; Iwade, Nobuyuki; Tuerde, Dilina; Kaibuchi, Kozo; Yamashita, Takayuki; Yamanaka, Akihiro; Katsuno, Masahisa; Watanabe, Hirohisa; Sobue, Gen; Ishigaki, Shinsuke Share Save
Cerebellar and thalamic connector hubs facilitate the involvement of visual and cognitive networks in essential tremor Bagarinao, Epifanio; Maesawa, Satoshi; Kato, Sachiko; Mutoh, Manabu; Ito, Yoshiki; Ishizaki, Tomotaka; Tanei, Takafumi; Tsuboi, Takashi; Suzuki, Masashi; Watanabe, Hirohisa; Hoshiyama, Minoru; Isoda, Haruo; Katsuno, Masahisa; Sobue, Gen; Saito, Ryuta Share Save
Phase 3, open-label, multicenter safety study of oral edaravone in patients with amyotrophic lateral sclerosis (MT-1186-A01): 48-week results Genge, Angela; Pattee, Gary L.; Sobue, Gen; Couratier, Philippe; Selness, Daniel; Bidani, Sachin; Hirai, Manabu; Salah, Alejandro; Apple, Stephen Share Save
Phase 3B study evaluating superiority of daily dosing vs approved on/off oral edaravone dosing over 48 weeks in patients with amyotrophic lateral sclerosis (MT-1186-A02) Salah, Alejandro; Desilva, Shari; Zinman, Lorne; Chum, Marvin; Chio, Adriano; Ludolph, Albert C.; Sobue, Gen; Doyu, Manabu; Selness, Daniel; Todorovic, Vesna; Hirai, Manabu; Wamil, Art; Apple, Stephen Share Save
Exercise attenuates polyglutamine-mediated neuromuscular degeneration in a mouse model of spinal and bulbar muscular atrophy Hirunagi, Tomoki; Nakatsuji, Hideaki; Sahashi, Kentaro; Yamamoto, Mikiyasu; Iida, Madoka; Tohnai, Genki; Kondo, Naohide; Yamada, Shinichiro; Murakami, Ayuka; Noda, Seiya; Adachi, Hiroaki; Sobue, Gen; Katsuno, Masahisa Share Save
Oral Edaravone - Introducing a Flexible Treatment Option for Amyotrophic Lateral Sclerosis Pattee, Gary L.; Genge, Angela; Couratier, Philippe; Lunetta, Christian; Sobue, Gen; Aoki, Masashi; Yoshino, Hiide; Jackson, Carlayne E.; Wymer, James; Salah, Alejandro; Nelson, Sally Share Save
Simple and efficient differentiation of human iPSCs into contractible skeletal muscles for muscular disease modeling Rashid, Muhammad Irfanur; Ito, Takuji; Miya, Fuyuki; Shimojo, Daisuke; Arimoto, Kanae; Onodera, Kazunari; Okada, Rina; Nagashima, Takunori; Yamamoto, Kazuki; Khatun, Zohora; Shimul, Rayhanul Islam; Niwa, Jun-ichi; Katsuno, Masahisa; Sobue, Gen; Okano, Hideyuki; Sakurai, Hidetoshi; Shimizu, Kazunori; Doyu, Manabu; Okada, Yohei Share Save
Genetic factors affecting survival in Japanese patients with sporadic amyotrophic lateral sclerosis: a genome-wide association study and verification in iPSC-derived motor neurons from patients Nakamura, Ryoichi; Tohnai, Genki; Nakatochi, Masahiro; Atsuta, Naoki; Watanabe, Hirohisa; Ito, Daisuke; Katsuno, Masahisa; Hirakawa, Akihiro; Izumi, Yuishin; Morita, Mitsuya; Hirayama, Takehisa; Kano, Osamu; Kanai, Kazuaki; Hattori, Nobutaka; Taniguchi, Akira; Suzuki, Naoki; Aoki, Masashi; Iwata, Ikuko; Yabe, Ichiro; Shibuya, Kazumoto; Kuwabara, Satoshi; Oda, Masaya; Hashimoto, Rina; Aiba, Ikuko; Ishihara, Tomohiko; Onodera, Osamu; Yamashita, Toru; Abe, Koji; Mizoguchi, Kouichi; Shimizu, Toshio; Ikeda, Yoshio; Yokota, Takanori; Hasegawa, Kazuko; Tanaka, Fumiaki; Nakashima, Kenji; Kaji, Ryuji; Niwa, Jun-ichi; Doyu, Manabu; Terao, Chikashi; Ikegawa, Shiro; Fujimori, Koki; Nakamura, Shiho; Ozawa, Fumiko; Morimoto, Satoru; Onodera, Kazunari; Ito, Takuji; Okada, Yohei; Okano, Hideyuki; Sobue, Gen Share Save
NOTCH2NLC GGC repeat expansion causes retinal pathology with intranuclear inclusions throughout the retina and causes visual impairment Sone, Jun; Ueno, Shinji; Akagi, Akio; Miyahara, Hiroaki; Tamai, Chisato; Riku, Yuichi; Yabata, Hiroyuki; Koizumi, Ryuichi; Hattori, Tomohiro; Hirose, Hiroshi; Koyanagi, Yoshito; Kobayashi, Rei; Okada, Hisashi; Kishimoto, Yoshiyuki; Hashizume, Yoshio; Sobue, Gen; Yoshida, Mari; Iwasaki, Yasushi Share Save
Phase 3, Open-Label, Multicenter Safety Study of Oral Edaravone in Patients With Amyotrophic Lateral Sclerosis (MT-1186-A01): 48-Week Results Genge, Angela; Pattee, Gary; Sobue, Gen; Couratier, Philippe; Selness, Daniel; Bidani, Sachin; Hirai, Manabu; Sakata, Takeshi; Salah, Alejandro; Apple, Stephen Share Save
Magnetic resonance-guided focused ultrasound thalamotomy restored distinctive resting-state networks in patients with essential tremor Kato, Sachiko; Maesawa, Satoshi; Bagarinao, Epifanio; Nakatsubo, Daisuke; Tsugawa, Takahiko; Mizuno, Satomi; Kawabata, Kazuya; Tsuboi, Takashi; Suzuki, Masashi; Shibata, Masashi; Takai, Sou; Ishizaki, Tomotaka; Torii, Jun; Mutoh, Manabu; Saito, Ryuta; Wakabayashi, Toshihiko; Katsuno, Masahisa; Ozaki, Norio; Watanabe, Hirohisa; Sobue, Gen Share Save
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