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Plasma and Urine Metabolites Associated with Microperimetric Retinal Sensitivity in Age-Related Macular Degeneration Sourirajan, Krupa; Mendez, Kevin; Lains, Ines; Tsougranis, Gregory; Kang, Haemin; Kozak, Georgiy; Bannerman, Augustine; Bhat, Roshni; Choi, Hanna; Nigalye, Archana; Kim, Ivana K.; Vavvas, Demetrios G.; Wu, David M.; Liang, Liming; Miller, John B.; Miller, Joan W.; Lasky-Su, Jessica; Husain, Deeba Share Save
A deconvolution framework that uses single-cell sequencing plus a small benchmark data set for accurate analysis of cell type ratios in complex tissue samples Guo, Shuai; Liu, Xiaoqian; Cheng, Xuesen; Jiang, Yujie; Ji, Shuangxi; Liang, Qingnan; Koval, Andrew; Li, Yumei; Owen, Leah A.; Kim, Ivana K.; Aparicio, Ana; Lee, Sanghoon; Sood, Anil K.; Kopetz, Scott; Shen, John Paul; Weinstein, John N.; Deangelis, Margaret M.; Chen, Rui; Wang, Wenyi Share Save
Overloading And unpacKing (OAK) - droplet-based combinatorial indexing for ultra-high throughput single-cell multiomic profiling Wu, Bing; Bennett, Hayley M.; Ye, Xin; Sridhar, Akshayalakshmi; Eidenschenk, Celine; Everett, Christine; Nazarova, Evgeniya V.; Chen, Hsu-Hsin; Kim, Ivana K.; Deangelis, Margaret; Owen, Leah A.; Chen, Cynthia; Lau, Julia; Shi, Minyi; Lund, Jessica M.; Xavier-Magalhaes, Ana; Patel, Neha; Liang, Yuxin; Modrusan, Zora; Darmanis, Spyros Share Save
Metabolomic-derived endotypes of age-related macular degeneration (AMD): a step towards identification of disease subgroups Mendez, Kevin; Lains, Ines; Kelly, Rachel S.; Gil, Joao; Silva, Rufino; Miller, John; Vavvas, Demetrios G.; Kim, Ivana; Miller, Joan; Liang, Liming; Lasky-Su, Jessica A.; Husain, Deeba Share Save
Plasma Metabolites Associated with OCT Features of Age-Related Macular Degeneration Lains, Ines; Han, Xikun; Gil, Joao; Providencia, Joana; Nigalye, Archana; Alvarez, Rodrigo; Douglas, Vivian Paraskevi; Mendez, Kevin; Katz, Raviv; Tsougranis, Gregory; Li, Jinglun; Kelly, Rachel S.; Kim, Ivana K.; Lasky-Su, Jessica; Silva, Rufino; Miller, Joan W.; Liang, Liming; Vavvas, Demetrios; Miller, John B.; Husain, Deeba Share Save
Patterns of Gene Expression, Splicing, and Allele-Specific Expression Vary among Macular Tissues and Clinical Stages of Age-Related Macular Degeneration Shwani, Treefa; Zhang, Charles; Owen, Leah A.; Shakoor, Akbar; Vitale, Albert T.; Lillvis, John H.; Barr, Julie L.; Cromwell, Parker; Finley, Robert; Husami, Nadine; Au, Elizabeth; Zavala, Rylee A.; Graves, Elijah C.; Zhang, Sarah X.; Farkas, Michael H.; Ammar, David A.; Allison, Karen M.; Tawfik, Amany; Sherva, Richard M.; Li, Mingyao; Stambolian, Dwight; Kim, Ivana K.; Farrer, Lindsay A.; DeAngelis, Margaret M. Share Save
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Integrating genetics and metabolomics from multi- ethnic and multi-fluid data reveals putative mechanisms for age-related macular degeneration Han, Xikun; Lains, Ines; Li, Jun; Li, Jinglun; Chen, Yiheng; Yu, Bing; Qi, Qibin; Boerwinkle, Eric; Kaplan, Robert; Thyagarajan, Bharat; Daviglus, Martha; Joslin, Charlotte E.; Cai, Jianwen; Guasch-Ferre, Marta; Tobias, Deirdre K.; Rimm, Eric; Ascherio, Alberto; Costenbader, Karen; Karlson, Elizabeth; Mucci, Lorelei; Eliassen, A. Heather; Zeleznik, Oana; Miller, John; Vavvas, Demetrios G.; Kim, Ivana K.; Silva, Rufino; Miller, Joan; Hu, Frank; Willett, Walter; Lasky-Su, Jessica; Kraft, Peter; Richards, J. Brent; MacGregor, Stuart; Husain, Deeba; Liang, Liming Share Save
A multi-omics atlas of the human retina at single-cell resolution Liang, Qingnan; Cheng, Xuesen; Wang, Jun; Owen, Leah; Shakoor, Akbar; Lillvis, John L.; Zhang, Charles; Farkas, Michael; Kim, Ivana K.; Li, Yumei; DeAngelis, Margaret; Chen, Rui Share Save
Resource A systems biology approach uncovers novel disease mechanisms in age-related macular degeneration Orozco, Luz D.; Owen, Leah A.; Hofmann, Jeffrey; Stockwell, Amy D.; Tao, Jianhua; Haller, Susan; Mukundan, Vineeth T.; Clarke, Christine; Lund, Jessica; Sridhar, Akshayalakshmi; Mayba, Oleg; Barr, Julie L.; Zavala, Rylee A.; Graves, Elijah C.; Zhang, Charles; Husami, Nadine; Finley, Robert; Au, Elizabeth; Lillvis, John H.; Frakas, Michael H.; Shakoor, Akbar; Sherva, Richard; Kim, Ivana K.; Kaminker, Joshua S.; Townsend, Michael J.; Farrer, Lindsay A.; Yaspan, Brian L.; Chen, Hsu-Hsi; Deangles, Margaret M. Share Save
Integration with benchmark data of paired bulk and single-cell RNA sequencing data substantially improves the accuracy of bulk tissue deconvolution Guo, Shuai; Cheng, Xuesen; Koval, Andrew; Ji, Shuangxi; Liang, Qingnan; Li, Yumei; Owen, Leah A.; Kim, Ivana K.; Weinstein, John; Kopetz, Scott; Shen, John Paul; DeAngelis, Margaret M.; Chen, Rui Share Save
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Expression and subcellular localization of USH1C/harmonin in human retina provides insights into pathomechanisms and therapy Nagel-Wolfrum, Kerstin; Fadl, Benjamin R.; Becker, Mirjana M.; Wunderlich, Kirsten A.; Schaefer, Jessica; Sturm, Daniel; Fritze, Jacques; Guer, Burcu; Kaplan, Lew; Andreani, Tommaso; Goldmann, Tobias; Brooks, Matthew; Starostik, Margaret R.; Lokhande, Anagha; Apel, Melissa; Fath, Karl R.; Stingl, Katarina; Kohl, Susanne; DeAngelis, Margaret M.; Schlotzer-Schrehardt, Ursula; Kim, Ivana K.; Owen, Leah A.; Vetter, Jan M.; Pfeiffer, Norbert; Andrade-Navarro, Miguel A.; Grosche, Antje; Swaroop, Anand; Wolfrum, Uwe Share Save
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