Not logged in Lymphodepletion - an essential but undervalued part of the chimeric antigen receptor T-cell therapy cycle Lickefett, Benno; Chu, Lulu; Ortiz-Maldonado, Valentin; Warmuth, Linda; Barba, Pere; Doglio, Matteo; Henderson, David; Hudecek, Michael; Kremer, Andreas; Markman, Janet; Nauerth, Magdalena; Negre, Helene; Sanges, Carmen; Staber, Philipp B.; Tanzi, Rebecca; Delgado, Julio; Busch, Dirk H.; Kuball, Juergen; Luu, Maik; Jaeger, Ulrich Share Save
A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer Kendzia, Sandra; Franke, Susanne; Kroehler, Tarek; Golob-Schwarzl, Nicole; Schweiger, Caroline; Toeglhofer, Anna M.; Skofler, Christina; Uranitsch, Stefan; El-Heliebi, Amin; Fuchs, Julia; Punschart, Andreas; Stiegler, Philipp; Keil, Marlen; Hoffmann, Jens; Henderson, David; Lehrach, Hans; Yaspo, Marie-Laure; Reinhard, Christoph; Schaefer, Reinhold; Keilholz, Ulrich; Regenbrecht, Christian; Schicho, Rudolf; Fickert, Peter; Lax, Sigurd F.; Erdmann, Frank; Schulz, Marcel H.; Kiemer, Alexandra K.; Haybaeck, Johannes; Kessler, Sonja M. Share Save
Selection of data sets for FAIRification in drug discovery and development: Which, why, and how? Alharbi, Ebtisam; Gadiya, Yojana; Henderson, David; Zaliani, Andrea; Delfin-Rossaro, Alejandra; Cambon-Thomsen, Anne; Kohler, Manfred; Witt, Gesa; Welter, Danielle; Juty, Nick; Jay, Caroline; Engkvist, Ola; Goble, Carole; Reilly, Dorothy S.; Satagopam, Venkata; Ioannidis, Vassilios; Gu, Wei; Gribbon, Philip Share Save
Profiling plasma cell-free RNA (cfRNA) with the NanoString low input nCounter assay Huang, Chung-Ying (Alan); Warren, Sarah; Reeves, Jason; Wurden, Megan; Riordan, Tim; Boykin, Rich; Liu, Mingdong; Henderson, David; Hanson, Dan; Gerlach, Jay; Beechem, Joseph M. Share Save
Share Save
Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells Regan, Joseph L.; Schumacher, Dirk; Staudte, Stephanie; Steffen, Andreas; Haybaeck, Johannes; Keilholz, Ulrich; Schweiger, Caroline; Golob-Schwarzl, Nicole; Mumberg, Dominik; Henderson, David; Lehrach, Hans; Regenbrecht, Christian R. A.; Schaefer, Reinhold; Lange, Martin Share Save
Share Save
Phase I dose-escalation studies of roniciclib, a pan-cyclin-dependent kinase inhibitor, in advanced malignancies Bahleda, Rastislav; Grilley-Olson, Juneko E.; Govindan, Ramaswamy; Barlesi, Fabrice; Greillier, Laurent; Perol, Maurice; Ray-Coquard, Isabelle; Strumberg, Dirk; Schultheis, Beate; Dy, Grace K.; Zalcman, Gerard; Weiss, Glen J.; Walter, Annette O.; Kornacker, Martin; Rajagopalan, Prabhu; Henderson, David; Nogai, Hendrik; Ocker, Matthias; Soria, Jean-Charles Share Save
Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors Schuette, Moritz; Risch, Thomas; Abdavi-Azar, Nilofar; Boehnke, Karsten; Schumacher, Dirk; Keil, Marlen; Yildirimman, Reha; Jandrasits, Christine; Borodina, Tatiana; Amstislavskiy, Vyacheslav; Worth, Catherine L.; Schweiger, Caroline; Liebs, Sandra; Lange, Martin; Warnatz, Hans-Joerg; Butcher, Lee M.; Barrett, James E.; Sultan, Marc; Wierling, Christoph; Golob-Schwarzl, Nicole; Lax, Sigurd; Uranitsch, Stefan; Becker, Michael; Welte, Yvonne; Regan, Joseph Lewis; Silvestrov, Maxine; Kehler, Inge; Fusi, Alberto; Kessler, Thomas; Herwig, Ralf; Landegren, Ulf; Wienke, Dirk; Nilsson, Mats; Velasco, Juan A.; Garin-Chesa, Pilar; Reinhard, Christoph; Beck, Stephan; Schaefer, Reinhold; Regenbrecht, Christian R. A.; Henderson, David; Lange, Bodo; Haybaeck, Johannes; Keilholz, Ulrich; Hoffmann, Jens; Lehrach, Hans; Yaspo, Marie-Laure Share Save
The role of Hedgehog signaling in the regulation of human colon cancer stem cells Regan, Joseph L.; Staudte, Stephanie; Schumacher, Dirk; Keilholz, Ulrich; Haybaeck, Johannes; Lehrach, Hans; Yaspo, Marie-Laure; Henderson, David; Steffen, Andreas; Toedling, Joern; Lesche, Ralf; Schaefer, Reinhold; Regenbrecht, Christian R.; Mumberg, Dominik; Lange, Martin Share Save
Whole transcriptome analysis of patient-derived 3D in vitro and xenograft models of colon cancer identifies placental genes required for the survival of cancer stem cells Regan, Joseph L.; Staudte, Stephanie; Schumacher, Dirk; Keilholz, Ulrich; Haybaeck, Johannes; Lehrach, Hans; Yaspo, Marie-Laure; Henderson, David; Steffen, Andreas; Toedling, Joern; Lesche, Ralf; Schaefer, Reinhold; Regenbrecht, Christian R.; Mumberg, Dominik; Lange, Martin Share Save
Key factors for successful data integration in biomarker research Elefsinioti, Antigoni; Bellaire, Tanja; Wang, Albert; Quast, Karsten; Seidel, Henrik; Braxenthaler, Michael; Goeller, Gernot; Christianson, Anastasia; Henderson, David; Reischl, Joachim Share Save
3D-models of patient-derived colon tumors for the identification of genetic factors important in the regulation of cancer stem cells Regan, Joseph L.; Schumacher, Dirk; Staudte, Stephanie; Boehnke, Karsten; Keilholz, Ulrich; Haybaeck, Johannes; Lehrach, Hans; Henderson, David; Schaefer, Reinhold; Regenbrecht, Christian R.; Mumberg, Dominik; Lange, Martin Share Save
A pipeline within the OncoTrack project for generating Patient-tumor-derived 3D cell cultures (PT3DC) and their application for individualized, targeted drug sensitivity assays Schumacher, Dirk; Boehnke, Karsten; Lange, Martin; Welte, Yvonne; Davies, Cathrin; Rivera, Maria; Keil, Marlen; Keilholz, Ulrich; Haybaeck, Johannes; Angel Velasco, Juan; Yaspo, Marie-Laure; Lehrach, Hans; Henderson, David; Reinhard, Christoph; Hoffmann, Jens; Schaefer, Reinhold; Regenbrecht, Christian Share Save
Generation of drug response data from 57 new patient-derived colon cancer xenografts and 3D cell cultures for systematic correlation with tumor biology within the OncoTrack* project Rivera, Maria; Keil, Marlen; Boehnke, Karsten; Lange, Martin; Schumacher, Dirk; Schaefer, Reinhold; Regenbrecht, Christian R.; Henderson, David; Keilholz, Ulrich; Kuehn, Alexander; El-Heliebi, Amin; Hohensee, Tabea; Haybaeck, Johannes; Reinhard, Christoph; Velasco, Juan A.; Lehrach, Hans; Garin-Chesa, Pilar; Beran, Garry; Hoffmann, Jens Share Save
Functional and molecular characterization of colon cancer stem cells in tumor heterogeneity and disease relapse using a 3D-model of patient-derived tumors Regan, Joseph L.; Schumacher, Dirk; Boehnke, Karsten; Davies, Cathrin; Keilholz, Ulrich; Haybaeck, Johannes; Reinhard, Christoph; Lehrach, Hans; Henderson, David; Schaefer, Reinhold; Regenbrecht, Christian; Lange, Martin Share Save
Share Save
First-in-human phase I dose escalation study of a novel anti-mesothelin antibody drug conjugate (ADC), BAY 94-9343, in patients with advanced solid tumors. Bendell, Johanna; Blumenschein, George; Zinner, Ralph; Hong, David; Jones, Suzanne; Infante, Jeffrey; Burris, Howard; Rajagopalan, Prabhu; Kornacker, Martin; Henderson, David; Kelly, Andrea; Hassan, Raffit Share Save
Efficacy and candidate biomarker evaluation for the anti-mesothelin antibody drug conjugate (ADC) BAY 94-9343, mesothelin-ADC in mesothelin-positive preclinical xenograft models Schatz, Christoph A.; Golfier, Sven; Scheider, Claudia; Kopitz, Charlotte; Berhoerster, Kerstin; Henderson, David; Schmitz, Arndt; Krahn, Thomas; Kreft, Bertolt; Ziegelbauer, Karl Share Save
.png){kind=icon}
.png){kind=icon}
Not logged in.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}