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TPC1 Has Two Variant Isoforms, and Their Removal Has Different Effects on Endo-Lysosomal Functions Compared to Loss of TPC2 Ruas, Margarida; Chuang, Kai-Ting; Davis, Lianne C.; Al-Douri, Areej; Tynan, Patricia W.; Tunn, Ruth; Teboul, Lydia; Galione, Antony; Parrington, John Share Save
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RSIV. F/HN-MEDIATED GENE THERAPY ENABLES LUNGS TO PRODUCE THERAPEUTICALLY RELEVANT LEVELS OF FVIII Pytel, K. M.; Paul-Smith, M. C.; McIntosh, J.; Chan, M.; Meng, C.; Pringle, I.; Davis, L.; Inoue, M.; Hasegawa, M.; Hyde, S. C.; Gill, D. R.; Nathwani, A. C.; Alton, E. W. F. W.; Griesenbach, U. Share Save
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Expression of Ca2+-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells Ruas, Margarida; Davis, Lianne C.; Chen, Cheng-Chang; Morgan, Anthony J.; Chuang, Kai-Ting; Walseth, Timothy F.; Grimm, Christian; Garnham, Clive; Powell, Trevor; Platt, Nick; Platt, Frances M.; Biel, Martin; Wahl-Schott, Christian; Parrington, John; Galione, Antony Share Save
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NAADP Activates Two-Pore Channels on T Cell Cytolytic Granules to Stimulate Exocytosis and Killing Davis, Lianne C.; Morgan, Anthony J.; Chen, Ji-Li; Snead, Charlotte M.; Bloor-Young, Duncan; Shenderov, Eugene; Stanton-Humphreys, Megan N.; Conway, Stuart J.; Churchill, Grant C.; Parrington, John; Cerundolo, Vincenzo; Galione, Antony Share Save
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Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca2+ Signaling and Endolysosomal Trafficking Ruas, Margarida; Rietdorf, Katja; Arredouani, Abdelilah; Davis, Lianne C.; Lloyd-Evans, Emyr; Koegel, Heidi; Funnell, Timothy M.; Morgan, Anthony J.; Ward, John A.; Watanabe, Keiko; Cheng, Xiaotong; Churchill, Grant C.; Zhu, Michael X.; Platt, Frances M.; Wessel, Gary M.; Parrington, John; Galione, Antony Share Save
Ca2+ Signaling Occurs via Second Messenger Release from Intraorganelle Synthesis Sites Davis, Lianne C.; Morgan, Anthony J.; Ruas, Margarida; Wong, Julian L.; Graeff, Richard M.; Poustka, Albert J.; Lee, Hon Cheung; Wessel, Gary M.; Parrington, John; Galione, Antony Share Save
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