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Leonardo Salmena

Faculty of Medicine

36H-index
200Paper Count
2.2WCitation Count
Published Papers 46
Publication Date
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A microRNA CRISPR screen reveals microRNA-483-3p as an apoptotic regulator in prostate cancer cells
errCell Death & Disease
IF9.6
err2025-10-24
err0
errOAAI
errJonathan Tak-Sum Chow; Ayeisha Desjardins; Daniel K. C. Lee; Iulia A. Grigore; Linda Lee; Norman J. Fu; Stephanie Chau; Byeong Yeop Lee; Martino Marco Gabra; Leonardo Salmena
errShare
errSave
The lipid phosphatase INPP4B controls pancreatic cancer cell migration and invasion by regulating fibronectin exocytosis
errJournal of Biological Chemistry
IF3.9
err2025-09-15
err0
errOAAI
errGolam T. Saffi; Nicholas Kleine; Leonardo Salmena
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errSave
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
errMolecular Oncology
IF4.5
err2025-07-30
err0
errOAAI
errDaniel K. C. Lee; Keyue Chen; Ryan Loke; Xiang Li; David Liubart; Golam T. Saffi; Jonathan T. S. Chow; Ché M. P. Melo; Lydia To; Leonardo Salmena
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errSave
Discovery of miRNA-mRNA regulatory networks in glioblastoma reveals novel insights into tumor microenvironment remodeling
errSCIENTIFIC REPORTS
IF3.9
err2024-11-11
err1
errOAAI
errGrigore, Iulia A.; Rajagopal, Athulram; Chow, Jonathan Tak-Sum; Stone, Thomas J.; Salmena, Leonardo
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errSave
The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate generation and Akt signaling
errMOLECULAR BIOLOGY OF THE CELL
IF2.7
err2024-09-01
err0
errOAAI
errChan, Victoria; Camardi, Cristina; Zhang, Kai; Orofiamma, Laura A.; Anderson, Karen E.; Hoque, Jafarul; Bone, Leslie N.; Awadeh, Yasmin; Lee, Daniel K. C.; Fu, Norman J.; Chow, Jonathan T. S.; Salmena, Leonardo; Stephens, Len R.; Hawkins, Phillip T.; Antonescu, Costin N.; Botelho, Roberto J.
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errSave
INPP4B promotes PDAC aggressiveness via PIKfyve and TRPML-1-mediated lysosomal exocytosis
errJOURNAL OF CELL BIOLOGY
IF6.4
err2024-08-09
err0
PREAI
errSaffi, Golam T.; To, Lydia; Kleine, Nicholas; Melo, Che M. P.; Chen, Keyue; Genc, Gizem; Lee, K. C. Daniel; Chow, Jonathan Tak-Sum; Jang, Gun Ho; Gallinger, Steven; Botelho, Roberto J.; Salmena, Leonardo
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errSave
'One way, or another, I'm gonna find ya': miR-221-3p finds its targets via small extracellular vesicles
errHAEMATOLOGICA
IF7.9
err2024-04-18
err0
errOAAI
errChow, Jonathan Tak-Sum; Salmena, Leonardo
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errSave
A screen to identify modifiers of BRCA1 protein level for cancer prevention and treatment
errCANCER RESEARCH
IF16.6
err2024-02-01
err0
PREAI
errSellars, Erin; Savguira, Margarita; Kotsopoulos, Joanne; Salmena, Leonardo
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errSave
Correlates of Circulating Osteoprotegerin in Women with a Pathogenic or Likely Pathogenic Variant in the BRCA1 Gene
errCANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
IF3.4
err2023-11-28
err0
PREAI
errPark, Sarah Sohyun; Zaman, Tasnim; Kim, Shana J.; Brooks, Jennifer D.; Wong, Andy Kin On; Lubinski, Jan; Narod, Steven A.; Salmena, Leonardo; Kotsopoulos, Joanne
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errSave
Stroma-derived miR-214 coordinates tumor dissemination
errJOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
err2023-01-13
err10
errOAAI
errOrso, Francesca; Virga, Federico; Dettori, Daniela; Dalmasso, Alberto; Paradzik, Mladen; Savino, Aurora; Pomatto, Margherita A. C.; Quirico, Lorena; Cucinelli, Stefania; Coco, Martina; Mareschi, Katia; Fagioli, Franca; Salmena, Leonardo; Camussi, Giovanni; Provero, Paolo; Poli, Valeria; Mazzone, Massimiliano; Pandolfi, Pier Paolo; Taverna, Daniela
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errSave
Mitochondrion-targeted RNA therapies as a potential treatment strategy for mitochondrial diseases
errMOLECULAR THERAPY-NUCLEIC ACIDS
IF0
err2022-12-01
err13
errOAAI
errChernega, Timofei; Choi, Jaehyoung; Salmena, Leonardo; Andreazza, Ana Cristina
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errSave
Inhibition of lipid kinase PIKfyve reveals a role for phosphatase Inpp4b in the regulation of PI(3)P-mediated lysosome dynamics through VPS34 activity
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-08-01
err6
errOAAI
errSaffi, Golam T.; Wang, Cheng An; Mangialardi, Emily M.; Vacher, Jean; Botelho, Roberto J.; Salmena, Leonardo
errShare
errSave
Increased Serum Mir-150-3p Expression Is Associated with Radiological Lung Injury Improvement in Patients with COVID-19
errVIRUSES-BASEL
IF3.5
err2022-06-23
err3
errOAAI
errBueno, Larissa C. M.; Paim, Layde R.; Minin, Eduarda O. Z.; da Silva, Luis Miguel; Mendes, Paulo R.; Kiyota, Tatiana A.; Schreiber, Angelica Z.; Bombassaro, Bruna; Mansour, Eli; Moretti, Maria Luiza; Chow, Jonathan Tak-Sum; Salmena, Leonardo; Coelho-Filho, Otavio R.; Velloso, Licio A.; Nadruz, Wilson; Schreiber, Roberto
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errSave
Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML
errCELL REPORTS
IF6.9
err2022-03-01
err6
errOAAI
errKrivdova, Gabriela; Voisin, Veronique; Schoof, Erwin M.; Marhon, Sajid A.; Murison, Alex; McLeod, Jessica L.; Gabra, Martino M.; Zeng, Andy G. X.; Aigner, Stefan; Yee, Brian A.; Shishkin, Alexander A.; Van Nostrand, Eric L.; Hermans, Karin G.; Trotman-Grant, Aaron C.; Mbong, Nathan; Kennedy, James A.; Gan, Olga, I; Wagenblast, Elvin; De Carvalho, Daniel D.; Salmena, Leonardo; Minden, Mark D.; Bader, Gary D.; Yeo, Gene W.; Dick, John E.; Lechman, Eric R.
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errSave
Investigating inositol polyphosphate-4-phosphatase, type II (INPP4B) signaling and role in acute myeloid leukemia
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2021-12-01
err0
PREAI
errChen, Keyue; Genc, Gizem E.; Woolley, John F.; Lee, Daniel K. C.; Botelho, Roberto J.; Salmena, Leonardo
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errSave
Using CRISPR-Cas9 screens to identify microRNA involved in aggressive prostate cancer phenotypes
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2021-12-01
err0
PREAI
errChow, Jonathan Tak-Sum; Lee, Daniel K. C.; Gabra, Martino Marco; Fu, Norman; Chen, Keyue; Salmena, Leonardo
errShare
errSave
A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer (vol 45, pg 747, 2013)
errNATURE GENETICS
IF31.8
err2020-09-03
err1
errOAAI
errLunardi, Andrea; Ala, Ugo; Epping, Mirjam T.; Salmena, Leonardo; Clohessy, John G.; Webster, Kaitlyn A.; Wang, Guocan; Mazzucchelli, Roberta; Bianconi, Maristella; Stack, Edward C.; Lis, Rosina; Patnaik, Akash; Cantley, Lewis C.; Bubley, Glenn; Cordon-Cardo, Carlos; Gerald, William L.; Montironi, Rodolfo; Signoretti, Sabina; Loda, Massimo; Nardella, Caterina; Pandolfi, Pier Paolo
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errSave
PTENP1is a ceRNA forPTEN: it's CRISPR clear
errJOURNAL OF HEMATOLOGY & ONCOLOGY
IF40.4
err2020-06-09
err15
errOAAI
errVitiello, Marianna; Evangelista, Monica; Zhang, Yang; Salmena, Leonardo; Pandolfi, Pier Paolo; Poliseno, Laura
errShare
errSave
The Complex Landscape of PTEN mRNA Regulation
errCOLD SPRING HARBOR PERSPECTIVES IN MEDICINE
IF10.1
err2019-12-23
err12
errOAAI
errSellars, Erin; Gabra, Martino; Salmena, Leonardo
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errSave
microRNAs and Acute Myeloid Leukemia Chemoresistance: A Mechanistic Overview
errFRONTIERS IN ONCOLOGY
IF3.3
err2017-10-30
err65
errOAAI
errGabra, Martino Marco; Salmena, Leonardo
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
L
Lewis C. Cantley
H-index: 214 · Papers: 1.4K
T
Tak W. Mak
H-index: 181 · Papers: 1.6K
R
Roderick T. Bronson
H-index: 164 · Papers: 1.1K
P
Pier Paolo Pandolfi
H-index: 160 · Papers: 818
C
Carlos Cordon‐Cardo
H-index: 154 · Papers: 936
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