Not logged in A GENOME-WIDE IN VIVO CRISPR ACTIVATION SCREEN IDENTIFIES BACE1 AS A THERAPEUTIC VULNERABILITY OF LUNG CANCER BRAIN METASTASIS Chafe, Shawn; Zhai, Kui; Aghaei, Nikoo; Miletic, Petar; Huang, Zhi; Brown, Kevin; Mobilio, Daniel; Young, Daniel; Suk, Yujin; Grewal, Shan; Mckenna, Dillon; Alizada, Zahra; Kieliszek, Agata; Lam, Fred; Escudero, Laura; Huang, Qian; Huebner, Ariana; Lu, Jack; Ang, Patrick; Anand, Alisha; Custers, Stefan; Apel, Erika; Slassi, Sarah; Brakel, Benjamin; Kim, Jongmyung; Liu, James; Bassey-Archibong, Blessing; Abdo, Rober; Shargall, Yaron; Lu, Jian-Qiang; Cutz, Jean-Claude; Zhang, Qi; Li, Shawn; Venugopal, Chitra; Hynds, Robert; Dufour, Antoine; Moffat, Jason; Swanton, Charles; Bao, Shideng; Singh, Sheila Share Save
THERAPEUTIC TARGETING OF MISLOCALIZED NUCLEAR ENVELOPE PROTEINS INMYC-DRIVEN GROUP 3 MEDULLOBLASTOMA Suk, Yujin; Ibanez-Vega, Jorge; Chaudhry, Iqra; Rossotti, Martin; Subapanditha, Minomi; Miletic, Petar; Custers, Stefan; Escudero, Laura; Delaidelli, Alberto; Nakashima, Takuma; Xiao, Yuxi; Moffat, Jason; Suzuki, Hiromichi; Sorensen, Poul; Henry, Kevin; Venugopal, Chitra; Krenciute, Giedre; Singh, Sheila Share Save
De novo GTP synthesis is a metabolic vulnerability for the interception of brain metastases Kieliszek, Agata M.; Mobilio, Daniel; Bassey-Archibong, Blessing I.; Johnson, Jarrod W.; Piotrowski, Mathew L.; de Araujo, Elvin D.; Sedighi, Abootaleb; Aghaei, Nikoo; Escudero, Laura; Ang, Patrick; Gwynne, William D.; Zhang, Cunjie; Quaile, Andrew; McKenna, Dillon; Subapanditha, Minomi; Tokar, Tomas; Shaikh, Muhammad Vaseem; Zhai, Kui; Chafe, Shawn C.; Gunning, Patrick T.; Montenegro-Burke, J. Rafael; Venugopal, Chitra; Magolan, Jakob; Singh, Sheila K. Share Save
Discovery of nuclear envelope mislocalization in MYC-driven group 3 medulloblastoma Suk, Yujin; Ibanez-Vega, Jorge; Chaudhry, Iqra; Rossotti, Martin; Subapanditha, Minomi; Miletic, Petar; Custers, Stefan; Escudero, Laura; Delaidelli, Alberto; Nakashima, Takuma; Xiao, Yuxi; Moffat, Jason; Suzuki, Hiromichi; Sorensen, Poul; Henry, Kevin; Venugopal, Chitra; Krenciute, Giedre; Singh, Sheila Share Save
Rational development of synergistic therapies alongside BMI1 Inhibition for group 3 medulloblastoma Bakhshinyan, David; Custers, Stefan; Adile, Ashley; Brown, Kevin; Qazi, Maleeha; Chokshi, Chirayu; Escudero, Laura; Suk, Yujin; Venugopal, Chitra; Moffat, Jason; Singh, Sheila Share Save
Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma Singh, Sheila; Gwynne, William; Suk, Yujin; Chan, Jeremy; Qualie, Andrew; Escudero, Laura; Brown, Kevin; Venugopal, Chitra; Moffat, Jason; Montenegro-Burke, Rafael Share Save
SCD1 is a potent therapeutic target in MYC-amplified group 3 medulloblastoma Custers, Stefan; Escudero, Laura; Suk, Yujin; McKenna, Dillon; Gwynne, William; Chaudhry, Iqra; Chan, Jeremy; Quaile, Andrew; Moffat, Jason; Venugopal, Chitra; Montenegro-Burke, Rafael; Singh, Sheila Share Save
Intratumoral Delivery of Chimeric Antigen Receptor T Cells Targeting CD133 Effectively Treats Brain Metastases Kieliszek, Agata M.; Mobilio, Daniel; Upreti, Deepak; Bloemberg, Darin; Escudero, Laura; Kwiecien, Jacek M.; Alizada, Zahra; Zhai, Kui; Ang, Patrick; Chafe, Shawn C.; Vora, Parvez; Venugopal, Chitra; Singh, Sheila K. Share Save
Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma Gwynne, William D.; Suk, Yujin Suk; Custers, Stefan; Mikolajewicz, Nicholas; Chan, Jeremy K.; Zador, Zsolt; Chafe, Shawn C.; Zhai, Kui; Escudero, Laura; Zhang, Cunjie; Zaslaver, Olga; Chokshi, Chirayu; Shaikh, Muhammad Vaseem; Bakhshinyan, David; Burns, Ian; Chaudhry, Iqra; Nachmani, Omri; Mobilio, Daniel; Maich, William T.; Mero, Patricia; Brown, Kevin R.; Quaile, Andrew T.; Venugopal, Chitra; Moffat, Jason; Montenegro-Burke, J. Rafael; Singh, Sheila K. Share Save
Share Save
Share Save
Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment Rubio-Perez, Carlota; Planas-Rigol, Ester; Trincado, Juan L.; Bonfill-Teixidor, Ester; Arias, Alexandra; Marchese, Domenica; Moutinho, Catia; Serna, Garazi; Pedrosa, Leire; Iurlaro, Raffaella; Martinez-Ricarte, Francisco; Escudero, Laura; Cordero, Esteban; Cicuendez, Marta; Ruiz, Sara; Parra, Genis; Nuciforo, Paolo; Gonzalez, Josep; Pineda, Estela; Sahuquillo, Juan; Tabernero, Josep; Heyn, Holger; Seoane, Joan Share Save
Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma Escudero, Laura; Llort, Anna; Arias, Alexandra; Diaz-Navarro, Ander; Martinez-Ricarte, Francisco; Rubio-Perez, Carlota; Mayor, Regina; Caratu, Ginevra; Martinez-Saez, Elena; Vazquez-Mendez, Elida; Lesende-Rodriguez, Ivan; Hladun, Raquel; Gros, Luis; Ramon y Cajal, Santiago; Poca, Maria A.; Puente, Xose S.; Sahuquillo, Juan; Gallego, Soledad; Seoane, Joan Share Save
Share Save
Cell free circulating tumor DNA in cerebrospinal fluid detects and monitors central nervous system involvement of B-cell lymphomas Bobillo, Sabela; Crespo, Marta; Escudero, Laura; Mayor, Regina; Raheja, Priyanka; Carpio, Cecilia; Rubio-Perez, Carlota; Tazon-Vega, Barbara; Palacio, Carlos; Carabia, Julia; Jimenez, Isabel; Nieto, Juan C.; Montoro, Julia; Martinez-Ricarte, Francisco; Castellvi, Josep; Simo, Marc; Puigdefabregas, Lluis; Abrisqueta, Pau; Bosch, Francesc; Seoane, Joan Share Save
LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy Pascual-Garcia, Monica; Bonfill-Teixidor, Ester; Planas-Rigol, Ester; Rubio-Perez, Carlota; Ludaro, Raffaella; Arias, Alexandra; Cuartas, Isabel; Sala-Hojman, Ada; Escudero, Laura; Martinez-Ricarte, Francisco; Huber-Ruano, Isabel; Nuciforo, Paolo; Pedrosa, Leire; Marques, Carolina; Brana, Irene; Garralda, Elena; Vieito, Maria; Squatrito, Massimo; Pineda, Estela; Graus, Francesc; EspejoH, Carmen; Sahuquillo, Juan; Tabernero, Josep; Seoane, Joan Share Save
Share Save
Share Save
.png){kind=icon}
.png){kind=icon}
Not logged in.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}