Not logged in Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity Kenyon, Emma J.; Kirkwood, Nerissa K.; Kitcher, Sian R.; Goodyear, Richard J.; Derudas, Marco; Cantillon, Daire M.; Baxendale, Sarah; de Leon, Antonio de la Vega; Mahieu, Virginia N.; Osgood, Richard T.; Wilson, Charlotte Donald; Bull, James C.; Waddell, Simon J.; Whitfield, Tanya T.; Ward, Simon E.; Kros, Corne J.; Richardson, Guy P. Share Save
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Identification of ion-channel modulators that protect against aminoglycosideinduced hair cell death Kenyon, Emma J.; Kirkwood, Nerissa K.; Kitcher, Sian R.; O'Reilly, Molly; Derudas, Marco; Cantillon, Daire M.; Goodyear, Richard J.; Secker, Abigail; Baxendale, Sarah; Bull, James C.; Waddell, Simon J.; Whitfield, Tanya T.; Ward, Simon E.; Kros, Corne J.; Richardson, Guy P. Share Save
Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning Shaya, Oren; Binshtok, Udi; Hersch, Micha; Rivkin, Dmitri; Weinreb, Sheila; Amir-Zilberstein, Liat; Khamaisi, Bassma; Oppenheim, Olya; Desai, Ravi A.; Goodyear, Richard J.; Richardson, Guy P.; Chen, Christopher S.; Sprinzak, David Share Save
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The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells Pepermans, Elise; Michel, Vincent; Goodyear, Richard; Bonnet, Crystel; Abdi, Samia; Dupont, Typhaine; Gherbi, Souad; Holder, Muriel; Makrelouf, Mohamed; Hardelin, Jean-Pierre; Marlin, Sandrine; Zenati, Akila; Richardson, Guy; Avan, Paul; Bahloul, Amel; Petit, Christine Share Save
Three deaf mice: mouse models for TECTA-based human hereditary deafness reveal domain-specific structural phenotypes in the tectorial membrane Legan, P. Kevin; Goodyear, Richard J.; Morin, Matias; Mencia, Angeles; Pollard, Hilary; Olavarrieta, Leticia; Korchagina, Julia; Modamio-Hoybjor, Silvia; Mayo, Fernando; Moreno, Felipe; Moreno-Pelayo, Miguel-Angel; Richardson, Guy P. Share Save
Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2 Furness, David N.; Johnson, Stuart L.; Manor, Uri; Ruettiger, Lukas; Tocchetti, Arianna; Offenhauser, Nina; Olt, Jennifer; Goodyear, Richard J.; Vijayakumar, Sarath; Dai, Yuhai; Hackney, Carole M.; Franz, Christoph; Di Fiore, Pier Paolo; Masetto, Sergio; Jones, Sherri M.; Knipper, Marlies; Holley, Matthew C.; Richardson, Guy P.; Kachar, Bechara; Marcotti, Walter Share Save
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A Mutation in PNPT1, Encoding Mitochondrial-RNA-Import Protein PNPase, Causes Hereditary Hearing Loss von Ameln, Simon; Wang, Geng; Boulouiz, Redouane; Rutherford, Mark A.; Smith, Geoffrey M.; Li, Yun; Pogoda, Hans-Martin; Nuernberg, Gudrun; Stiller, Barbara; Volk, Alexander E.; Borck, Guntram; Hong, Jason S.; Goodyear, Richard J.; Abidi, Omar; Nuernberg, Peter; Hofmann, Kay; Richardson, Gu Y. P.; Hammerschmidt, Matthias; Moser, Tobias; Wollnik, Bernd; Koehler, Carla M.; Teitell, Michael A.; Barakat, Abdelhamid; Kubisch, Christian Share Save
Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia Caberlotto, Elisa; Michel, Vincent; Foucher, Isabelle; Bahloul, Amel; Goodyear, Richard J.; Pepermans, Elise; Michalski, Nicolas; Perfettini, Isabelle; Alegria-Prevot, Olinda; Chardenoux, Sebastien; Do Cruzeiro, Marcio; Hardelin, Jean-Pierre; Richardson, Guy P.; Avan, Paul; Weil, Dominique; Petit, Christine Share Save
Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with α-tectorin and is mutated in autosomal dominant hearing loss (DFNA4) Zheng, Jing; Miller, Katharine K.; Yang, Tao; Hildebrand, Michael S.; Shearer, A. Eliot; DeLuca, Adam P.; Scheetz, Todd E.; Drummond, Jennifer; Scherer, Steve E.; Legan, P. Kevin; Goodyear, Richard J.; Richardson, Guy P.; Cheatham, Mary Ann; Smith, Richard J.; Dallos, Peter Share Save
In vivo and in vitro effects of two novel gamma-actin (ACTG1) mutations that cause DFNA20/26 hearing impairment Morin, Matias; Bryan, Keith E.; Mayo-Merino, Fernando; Goodyear, Richard; Mencia, Angeles; Modamio-Hoybjor, Silvia; del Castillo, Ignacio; Cabalka, Jessica M.; Richardson, Guy; Moreno, Felipe; Rubenstein, Peter A.; Angel Moreno-Pelayo, Miguel Share Save
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Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly Delprat, B; Michel, V; Goodyear, R; Yamasaki, Y; Michalski, N; El-Amraoui, A; Perfettini, I; Legrain, P; Richardson, G; Hardelin, JP; Petit, C Share Save
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Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase Ng, L; Goodyear, RJ; Woods, CA; Schneider, MJ; Diamond, E; Richardson, GP; Kelley, MW; St Germain, DL; Galton, VA; Forrest, D Share Save
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Otoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22 Zwaenepoel, I; Mustapha, M; Leibovici, M; Verpy, E; Goodyear, R; Liu, XZ; Nouaille, S; Nance, WE; Kanaan, M; Avraham, KB; Tekaia, F; Loiselet, J; Lathrop, M; Richardson, G; Petit, C Share Save
Thyroid hormone-deficient period prior to the onset of hearing is associated with reduced levels of β-tectorin protein in the tectorial membrane -: Implication for hearing loss Knipper, M; Richardson, G; Mack, A; Müller, M; Goodyear, R; Limberger, A; Rohbock, K; Köpschall, I; Zenner, HP; Zimmermann, U Share Save