Not logged in Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury Cortada, Eric; Yao, Jun; Xia, Yu; Duendar, Friederike; Zumbo, Paul; Yang, Boris; Rubio-Navarro, Alfonso; Perder, Bjoern; Qiu, Miaoyan; Pettinato, Anthony M.; Homan, Edwin A.; Stoll, Lisa; Betel, Doron; Cao, Jingli; Lo, James C. Share Save
A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas Falvo, David J.; Grimont, Adrien; Zumbo, Paul; Fall, William B.; Yang, Julie L.; Osterhoudt, Alexa; Pan, Grace; Rendeiro, Andre F.; Meng, Yinuo; Wilkinson, John E.; Dundar, Friederike; Elemento, Olivier; Yantiss, Rhonda K.; Hissong, Erika; Koche, Richard; Betel, Doron; Chandwani, Rohit Share Save
The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells (ACTG) A5321 Team Copertino, Dennis C., Jr.; Holmberg, Carissa S.; Weiler, Jared; Ward, Adam R.; Howard, J. Natalie; Levinger, Callie; Pang, Alina P. S.; Corley, Michael J.; Duendar, Friederike; Zumbo, Paul; Betel, Doron; Gandhi, Rajesh T.; McMahon, Deborah K.; Bosch, Ronald J.; Linden, Noemi; Macatangay, Bernard J.; Cyktor, Joshua C.; Eron, Joseph J.; Mellors, John W.; Kovacs, Colin; Benko, Erika; Bosque, Alberto; Jones, R. Brad Share Save
Hallmarks of CD8+ T cell dysfunction are established within hours of tumor antigen encounter before cell division Rudloff, Michael W.; Zumbo, Paul; Favret, Natalie R.; Roetman, Jessica J.; Roman, Carlos J. Detres R.; Erwin, Megan M.; Murray, Kristen A.; Jonnakuti, Sriya T.; Dundar, Friederike; Betel, Doron; Philip, Mary Share Save
Epsilon toxin-producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege Ma, Yinghua; Sannino, David; Linden, Jennifer R.; Haigh, Sylvia; Zhao, Baohua; Grigg, John B.; Zumbo, Paul; Duendar, Friederike; Butler, Daniel; Profaci, Caterina P.; Telesford, Kiel; Winokur, Paige N.; Rumah, Kareem R.; Gauthier, Susan A.; Fischetti, Vincent A.; McClane, Bruce A.; Uzal, Francisco A.; Zexter, Lily; Mazzucco, Michael; Rudick, Richard; Danko, David; Balmuth, Evan; Nealon, Nancy; Perumal, Jai; Kaunzner, Ulrike; Brito, Ilana L.; Chen, Zhengming; Xiang, Jenny Z.; Betel, Doron; Daneman, Richard; Sonnenberg, Gregory F.; Mason, Christopher E.; Vartanian, Timothy Share Save
A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes Rubio-Navarro, Alfonso; Gomez-Banoy, Nicolas; Stoll, Lisa; Dundar, Friederike; Mawla, Alex M.; Ma, Lunkun; Cortada, Eric; Zumbo, Paul; Li, Ang; Reiterer, Moritz; Montoya-Oviedo, Nathalia; Homan, Edwin A.; Imai, Norihiro; Gilani, Ankit; Liu, Chengyang; Naji, Ali; Yang, Boris; Chong, Angie Chi Nok; Cohen, David E.; Chen, Shuibing; Cao, Jingli; Pitt, Geoffrey S.; Huising, Mark O.; Betel, Doron; Lo, James C. C. Share Save
Activation of a transient progenitor state in the epicardium is required for zebrafish heart regeneration Xia, Yu; Duca, Sierra; Perder, Bjorn; Dundar, Friederike; Zumbo, Paul; Qiu, Miaoyan; Yao, Jun; Cao, Yingxi; Harrison, Michael R. M.; Zangi, Lior; Betel, Doron; Cao, Jingli Share Save
An epigenetic memory of inflammation controls context-dependent lineage plasticity in the pancreas Falvo, David J.; Grimont, Adrien; Zumbo, Paul; Yang, Julie L.; Osterhoudt, Alexa; Pan, Grace; Rendeiro, Andre F.; Wilkinson, John E.; Dundar, Friederike; Elemento, Olivier; Yantiss, Rhonda K.; Betel, Doron; Koch, Richard; Chandwani, Rohit Share Save
SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8+ T-cells Stevenson, Eva M.; Terry, Sandra; Copertino, Dennis; Leyre, Louise; Danesh, Ali; Weiler, Jared; Ward, Adam R.; Khadka, Pragya; McNeil, Evan; Bernard, Kevin; Miller, Itzayana G.; Ellsworth, Grant B.; Johnston, Carrie D.; Finkelsztein, Eli J.; Zumbo, Paul; Betel, Doron; Dundar, Friederike; Duncan, Maggie C.; Lapointe, Hope R.; Speckmaier, Sarah; Moran-Garcia, Nadia; Papa, Michelle Premazzi; Nicholes, Samuel; Stover, Carissa J.; Lynch, Rebecca M.; Caskey, Marina; Gaebler, Christian; Chun, Tae-Wook; Bosque, Alberto; Wilkin, Timothy J.; Lee, Guinevere Q.; Brumme, Zabrina L.; Jones, R. Brad Share Save
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Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA Chandran, Smita S.; Ma, Jiaqi; Klatt, Martin G.; Dundar, Friederike; Bandlamudi, Chaitanya; Razavi, Pedram; Wen, Hannah Y.; Weigelt, Britta; Zumbo, Paul; Fu, Si Ning; Banks, Lauren B.; Yi, Fei; Vercher, Enric; Etxeberria, Inaki; Bestman, Watchain D.; Da Cruz Paula, Arnaud; Aricescu, Ilinca S.; Drilon, Alexander; Betel, Doron; Scheinberg, David A.; Baker, Brian M.; Klebanoff, Christopher A. Share Save
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion Shakiba, Mojdeh; Zumbo, Paul; Espinosa-Carrasco, Gabriel; Menocal, Laura; Duendar, Friederike; Carson, Sandra E.; Bruno, Emmanuel M.; Sanchez-Rivera, Francisco J.; Lowe, Scott W.; Camara, Steven; Koche, Richard P.; Reuter, Vincent P.; Socci, Nicholas D.; Whitlock, Benjamin; Tamzalit, Fella; Huse, Morgan; Hellmann, Matthew D.; Wells, Daniel K.; Defranoux, Nadine A.; Betel, Doron; Philip, Mary; Schietinger, Andrea Share Save
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Selective BCL-XL Antagonists Eliminate Infected Cells from a Primary-Cell Model of HIV Latency but Not from Ex Vivo Reservoirs Ren, Yanqin; Huang, Szu Han; Macedo, Amanda B.; Ward, Adam R.; Alberto, Winiffer D. Conce; Klevorn, Thais; Leyre, Louise; Copertino, Dennis C.; Mota, Talia M.; Chan, Dora; Truong, Ronald; Rohwetter, Thomas; Zumbo, Paul; Dundar, Friederike; Betel, Doron; Kovacs, Colin; Benko, Erika; Bosque, Alberto; Jones, R. Brad Share Save
Epigenomically Bistable Regions across Neuron-Specific Genes Govern Neuron Eligibility to a Coding Ensemble in the Hippocampus Odell, Shannon C.; Taki, Faten; Klein, Shifra Liba; Chen, Rosa J.; Levine, Olivia B.; Skelly, Mary Jane; Nabila, Anika; Brindley, Elizabeth; Toth, Judit Gal; Dundar, Friederike; Sheridan, Caroline K.; Fetcho, Robert N.; Alonso, Alicia; Liston, Conor; Landau, Dan A.; Pleil, Kristen E.; Toth, Miklos Share Save
T cell receptor gene therapy for a public neoantigen derived from mutated PIK3CA, a dominant driver oncogene in breast and endometrial cancers Chandran, Smita; Ma, Jiaqi; Klatt, Martin G.; Dundar, Friederike; Zumbo, Paul; Femia, Matthew R.; Betel, Doron; Scheinberg, David A.; Baker, Brian M.; Klebanoff, Christopher A. Share Save
Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation Li, Qing V.; Dixon, Gary; Verma, Nipun; Rosen, Bess P.; Gordillo, Miriam; Luo, Renhe; Xu, Chunlong; Wang, Qiong; Soh, Chew-Li; Yang, Dapeng; Crespo, Miguel; Shukla, Abhijit; Xiang, Qing; Dundar, Friederike; Zumbo, Paul; Witkin, Matthew; Koche, Richard; Betel, Doron; Chen, Shuibing; Massague, Joan; Garippa, Ralph; Evans, Todd; Beer, Michael A.; Huangfu, Danwei Share Save
Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation Chlamydas, Sarantis; Holz, Herbert; Samata, Maria; Chelmicki, Tomasz; Georgiev, Plamen; Pelechano, Vicent; Dundar, Friederike; Dasmeh, Pouria; Mittler, Gerhard; Cadete, Filipe Tavares; Ramirez, Fidel; Conrad, Thomas; Wei, Wu; Raja, Sunil; Manke, Thomas; Luscombe, Nicholas M.; Steinmetz, Lars M.; Akhtar, Asifa Share Save
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MOF-associated complexes ensure stem cell identity and Xist repression Chelmicki, Tomasz; Duendar, Friederike; Turley, Matthew James; Khanam, Tasneem; Aktas, Tugce; Ramirez, Fidel; Gendrel, Anne-Valerie; Wright, Patrick Rudolf; Videm, Pavankumar; Backofen, Rolf; Heard, Edith; Manke, Thomas; Akhtar, Asifa Share Save
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