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W

W. Fraser Symmans

The University of Texas MD Anderson Cancer Center

105H-index
911Paper Count
4.9WCitation Count
Published Papers 218
Publication Date
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Zanidatamab in patients with early stage HER2-positive breast cancer: the NeoZanHER phase 2 single-arm open-label trial
errNature Communications
IF15.7
err2026-08-22
err0
errOAAI
errVicente Valero; Paula R. Pohlmann; Jason Mouabbi; Xuelin Huang; Wei Qiao; Heather Alonzo; Rashmi K. Murthy; Gaiane M. Rauch; Taiwo Adesoye; Cristina Checka; Fraser W. Symmans; Dmitrii Grachev; Flora Alajajyan; Adaeze Nwosu-Iheme; Amy Hassan; Miral Patel; Sharon H. Giordano; Kelly Hunt; Debasish Tripathy; Funda Meric-Bernstam
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Combination of predicted sensitivity to endocrine therapy (SET2,3 index) and the Recurrence Score® in node-positive breast cancer: independent validation in the PACS-01 trial.
errEuropean Journal of Cancer
IF7.1
err2025-12-01
err0
PREAI
errFrédérique Penault-Llorca; Amelie Lusque; Thomas Filleron; Kevin Tran; Lili Du; Rick Baehner; Florence Dalenc; Magali Lacroix-Triki; Thomas Bachelot; Fabrice Andre; Pascal Boucher; Jérôme Lemonnier; W. Fraser Symmans
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errSave
EMT-induced stem cell and mesenchymal programs can be decoupled via cell division and ESRP1-dependent mechanisms
erriScience
IF4.1
err2025-12-01
err0
errOAAI
errPetra den Hollander; Maria Castaneda; Suhas V. Vasaikar; Joanna Joyce Maddela; Claire Gould; Breanna R. Demestichas; Robiya Joseph; Shivangi Agarwal; Abhijeet P. Deshmukh; Alvina Zia; Shruti Shah; Tieling Zhou; Geraldine Raja; Paul Allegakoen; Nick A. Kuburich; Mika Pietila; Chunxiao Fu; Jeffrey Chang; Chad J. Creighton; William F. Symmans
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Neoadjuvant trastuzumab deruxtecan alone or followed by paclitaxel, trastuzumab, and pertuzumab for high-risk HER2-positive early breast cancer (DESTINY-Breast11): a randomised, open-label, multicentre, phase 3 trial
errAnnals of Oncology
IF65.4
err2025-10-21
err0
errOAAI
errNadia Harbeck; Shanu Modi; Lajos Pusztai; Shinji Ohno; Jiong Wu; Sung-Bae Kim; Atsushi Yoshida; Alessandra Fabi; Xuchen Cao; Rona Joseph; Rubi Li; Bogdan Żurawski; Santiago Escrivá-de-Romaní; Renata Meneguetti; Archara Supavavej; Shin-Cheh Chen; Zhenzhen Liu; Catherine Kelly; Giuseppe Curigliano; William F. Symmans; Mohammad Gufran; Jun Ke; Adam Konpa; Pia Herbolsheimer; Jean-François Boileau
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ASO Visual Abstract: Impact of Time to Surgery Post Neoadjuvant Chemotherapy on Breast Cancer Outcomes: A Retrospective Study of Patients Enrolled in the I-SPY 2 Clinical Trial
errAnnals of Surgical Oncology
IF3.5
err2025-08-29
err0
PREAI
errJulie Van Hassel; Katrina Dimitroff; Christina Yau; Rita Mukhtar; Judy C. Boughey; Velle Ladores; Marissa M. Howard-McNatt; Nora Jaskowiak; Jane Perlmutter; Angela DeMichele; Douglas Yee; Nola Hylton; W. Fraser Symmans; Laura van’t Veer; Hope Rugo; Laura J. Esserman; Rebecca Shatsky; Claudine Isaacs; Henry Kuerer; Anne M. Wallace; Nicolas Prionas; Jennifer Tseng; Chantal R. Reyna; Neil Taunk; Susan Kesmodel; Marie C. Lee; Jana Fox; Mara A. Piltin; Julia Tchou; Cletus A. Arciero; Lauren M. Postlewait; Candice Sauder; Roshni Rao
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Impact of Time to Surgery Post Neoadjuvant Chemotherapy on Breast Cancer Outcomes: A Retrospective Study of Patients Enrolled in the I-SPY 2 Clinical Trial
errAnnals of Surgical Oncology
IF3.5
err2025-08-23
err0
PREAI
errJulie Van Hassel; Katrina Dimitroff; Christina Yau; Rita Mukhtar; Judy C. Boughey; Velle Ladores; Marissa M. Howard-McNatt; Nora Jaskowiak; Jane Perlmutter; Angela DeMichele; Douglas Yee; Nola Hylton; W. Fraser Symmans; Laura van’t Veer; Hope Rugo; Laura J. Esserman; Rebecca Shatsky; Claudine Isaacs; Henry Kuerer; Anne M. Wallace; Nicolas Prionas; Jennifer Tseng; Chantal R. Reyna; Neil Taunk; Susan Kesmodel; Marie C. Lee; Jana Fox; Mara A. Piltin; Julia Tchou; Cletus A. Arciero; Lauren M. Postlewait; Candice Sauder; Roshni Rao
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ASO Visual Abstract: Impact of Neoadjuvant Chemotherapy on Surgical Outcomes and Conversion to Node-Negativity in Invasive Lobular Breast Cancer: Analysis of Molecularly High-Risk Tumors by Histologic Subtype on the I-SPY2 Clinical Trial
errAnnals of Surgical Oncology
IF3.5
err2025-08-23
err0
PREAI
errRita A. Mukhtar; Katrina Dimitroff; Christina Yau; A. Jo Chien; Eileen P. Connolly; Marissa Howard-McNatt; Roshni Rao; Velle Ladores; Mehra Golshan; Candice A. Sauder; Kamran Ahmed; Rachael Lancaster; Jana Fox; Lily Gutnik; M. Catherine Lee; Julia Tchou; Nicolas Prionas; Cletus A. Arciero; Chantal Reyna; Henry Kuerer; Kayla Switalla; Neil Taunk; Todd M. Tuttle; Meena S. Moran; Lauren M. Postlewait; Jane Perlmutter; Angela DeMichele; Douglas Yee; Nola Hylton; W. Fraser Symmans; Hope S. Rugo; Rebecca Shatsky; Claudine Isaacs; Laura J. Esserman; Laura van ‘t Veer; Judy C. Boughey
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Impact of Neoadjuvant Chemotherapy on Surgical Outcomes and Conversion to Node-Negativity in Invasive Lobular Breast Cancer: Analysis of Molecularly High-Risk Tumors by Histologic Subtype on the I-SPY2 Clinical Trial
errAnnals of Surgical Oncology
IF3.5
err2025-07-24
err0
errOAAI
errRita A. Mukhtar; Katrina Dimitroff; Christina Yau; A. Jo Chien; Eileen P. Connolly; Marissa Howard-McNatt; Roshni Rao; Velle Ladores; Mehra Golshan; Candice A. Sauder; Kamran Ahmed; Rachael Lancaster; Jana Fox; Lily Gutnik; M. Catherine Lee; Julia Tchou; Nicolas Prionas; Cletus A. Arciero; Chantal Reyna; Henry Kuerer; Kayla Switalla; Neil Taunk; Todd M. Tuttle; Meena S. Moran; Lauren M. Postlewait; Jane Perlmutter; Angela DeMichele; Douglas Yee; Nola Hylton; W. Fraser Symmans; Hope S. Rugo; Rebecca Shatsky; Claudine Isaacs; Laura J. Esserman; Laura van’t Veer; Judy C. Boughey
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errSave
Disparities in the Surgical Management of the Axilla by Self-Identified Race in the Multicenter Neoadjuvant I-SPY2 Trial
errAnnals of Surgical Oncology
IF3.5
err2025-07-23
err0
errOAAI
errMandeep Kaur; Katrina Dimitroff; Judy C. Boughey; Laura J. Esserman; Christina Yau; Julia Tchou; Astrid Quirarte; Marie Catherine Lee; Marissa M. Howard-McNatt; Kayla Switalla; Henry Kuerer; Candice Sauder; Lauren M. Postlewait; Cletus Arciero; Roshni Rao; Anne Wallace; Chantal Reyna; Kamran Ahmed; Lily Gutnik; Neil Taunk; Jane Perlmutter; Angela DeMichele; Douglas Yee; Nola M. Hylton; W. Fraser Symmans; Hope S. Rugo; Rebecca A. Shatsky; Claudine Isaacs; Sonali Rudra; Paula Pohlmann; Cheryl Ewing; Jasmine Wong; Michael Alvarado; Nora Jaskowiak; Nicolas Prionas; Mehra Golshan; Mara A. Piltin; Olufunmilayo I. Olopade; Rita A. Mukhtar
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Prospective and Retrospective Analysis of Whole-Slide Images of Sentinel and Targeted Lymph Node Frozen Sections in Breast Cancer
errMODERN PATHOLOGY
IF5.5
err2025-04-01
err0
PREAI
errYe, Qiqi; Law, Timothy; Klippel, Dianna; Albarracin, Constance; Chen, Hui; Contreras, Alejandro; Ding, Qingqing; Huo, Lei; Khazai, Laila; Middleton, Lavinia; Resetkova, Erika; Sahin, Aysegul; Sun, Hongxia; Sweeney, Keith; Symmans, William Fraser; Wu, Yun; Yoon, Esther; Krishnamurthy, Savitri
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Impact of adding palbociclib on treatment adherence to ongoing adjuvant endocrine treatment in the global randomized PALLAS randomized trial in patients with early breast cancer
errBREAST CANCER RESEARCH AND TREATMENT
IF3
err2025-03-01
err0
PREAI
errShinn, Eileen; Zahrieh, David; Demichele, Angela; Zdenkowski, Nick; Lemieux, Julie; Mao, Jun; Bjelic-Radisic, Vesna; Naughton, Michelle J.; Pfeiler, Georg; Gelmon, Karen; Balko, Justin M.; Egle, Daniel; Zoppoli, Gabriele; Traina, Tiffany; Jimenez, Miguel Martin; Novoa, Silvia Antolin; Haddad, Tufia; Chan, Arlene; Ring, Alistair; Wolff, Antonio; Symmans, William Fraser; Ponce Lorenzo, Jose; Sabanathan, Dhanusha; Burstein, Hal J.; Nowecki, Zbigniew Ireneusz; Pristauz-Telsnigg, Gunda; Brufsky, Adam; Bellet-Ezquerra, Meritxell; Foukakis, Theodoros; Novik, Yelena; Rubovszky, Gabor; Singer, Christian F.; Muehlbacher, Karoline; Filho, Otto Metzger; Goulioti, Theodora; Law, Ernest; Partridge, Ann H.; Carey, Lisa A.; Zoroufy, Alex; Hlauschek, Dominik; Fesl, Christian; Mayer, Erica L.; Gnant, Michael
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A pooled analysis evaluating prognostic significance of Residual Cancer Burden in invasive lobular breast cancer
errNPJ BREAST CANCER
IF7.6
err2025-02-13
err0
errOAAI
errMukhtar, Rita A.; Gottipati, Soumya; Yau, Christina; Lopez-Tarruella, Sara; Earl, Helena; Hayward, Larry; Hiller, Louise; Osdoit, Marie; van der Noordaa, Marieke; de Croze, Diane; Hamy, Anne-Sophie; Lae, Marick; Reyal, Fabien; Sonke, Gabe S.; Steenbruggen, Tessa G.; van Seijen, Maartje; Wesseling, Jelle; Martin, Miguel; del Monte-Millan, Maria; Boughey, Judy C.; Goetz, Matthew P.; Hoskin, Tanya; Valero, Vicente; Edge, Stephen B.; Abraham, Jean E.; Bartlett, John M. S.; Caldas, Carlos; Dunn, Janet; Provenzano, Elena; Sammut, Stephen-John; Thomas, Jeremy S.; Graham, Ashley; Hall, Peter; Mackintosh, Lorna; Fan, Fang; Godwin, Andrew K.; Schwensen, Kelsey; Sharma, Priyanka; Demichele, Angela M.; Cole, Kimberly; Pusztai, Lajos; Kim, Mi-Ok; van 't Veer, Laura; Cameron, David; Esserman, Laura J.; Fraser Symmans, W.
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Gene signatures derived from transcriptomic-causal networks stratify colorectal cancer patients for effective targeted therapy
errCOMMUNICATIONS MEDICINE
IF6.3
err2025-01-08
err0
errOAAI
errYazdani, Akram; Lenz, Heinz-Josef; Pillonetto, Gianluigi; Mendez-Giraldez, Raul; Yazdani, Azam; Sanoff, Hanna; Hadi, Reza; Samiei, Esmat; Venook, Alan P.; Ratain, Mark J.; Rashid, Naim; Vincent, Benjamin G.; Qu, Xueping; Wen, Yujia; Kosorok, Michael; Symmans, William F.; Shen, John Paul Y. C.; Lee, Michael S.; Kopetz, Scott; Nixon, Andrew B.; Bertagnolli, Monica M.; Perou, Charles M.; Innocenti, Federico
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Pexidartinib and standard neoadjuvant therapy in the adaptively randomized I-SPY2 trial for early breast cancer
errBREAST CANCER RESEARCH AND TREATMENT
IF3
err2024-12-03
err0
errOAAI
errRugo, Hope S.; Campbell, Mike; Yau, Christina; Jo Chien, A.; Wallace, Anne M.; Isaacs, Claudine; Boughey, Judy C.; Han, Hyo S.; Buxton, Meredith; Clennell, Julia L.; Asare, Smita M.; Steeg, Katherine; Wilson, Amy; Singhrao, Ruby; Matthews, Jeffrey B.; Perlmutter, Jane; Fraser Symmans, W.; Hylton, Nola M.; Demichele, Angela M.; Yee, Douglas; Van't Veer, Laura J.; Berry, Donald A.; Esserman, Laura J.
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errSave
Datopotamab-deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial
errNATURE MEDICINE
IF50
err2024-09-14
err1
PREAI
errKhoury, Katia; Meisel, Jane L.; Yau, Christina; Rugo, Hope S.; Nanda, Rita; Davidian, Marie; Tsiatis, Butch; Chien, A. Jo; Wallace, Anne M.; Arora, Mili; Rozenblit, Mariya; Hershman, Dawn L.; Zimmer, Alexandra; Clark, Amy S.; Beckwith, Heather; Elias, Anthony D.; Stringer-Reasor, Erica; Boughey, Judy C.; Nangia, Chaitali; Vaklavas, Christos; Omene, Coral; Albain, Kathy S.; Kalinsky, Kevin M.; Isaacs, Claudine; Tseng, Jennifer; Torres, Evanthia T. Roussos; Thomas, Brittani; Thomas, Alexandra; Sanford, Amy; Balassanian, Ronald; Ewing, Cheryl; Yeung, Kay; Sauder, Candice; Sanft, Tara; Pusztai, Lajos; Trivedi, Meghna S.; Outhaythip, Ashton; Li, Wen; Onishi, Natsuko; Asare, Adam L.; Beineke, Philip; Norwood, Peter; Brown-Swigart, Lamorna; Hirst, Gillian L.; Matthews, Jeffrey B.; Moore, Brian; Symmans, W. Fraser; Price, Elissa; Beedle, Carolyn; Perlmutter, Jane; Pohlmann, Paula; Shatsky, Rebecca A.; Demichele, Angela; Yee, Douglas; van't Veer, Laura J.; Hylton, Nola M.; Esserman, Laura J.
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Datopotamab-deruxtecan plus durvalumab in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial
errNATURE MEDICINE
IF50
err2024-09-14
err4
PREAI
errShatsky, Rebecca A.; Trivedi, Meghna S.; Yau, Christina; Nanda, Rita; Rugo, Hope S.; Davidian, Marie; Tsiatis, Butch; Wallace, Anne M.; Chien, A. Jo; Stringer-Reasor, Erica; Boughey, Judy C.; Omene, Coral; Rozenblit, Mariya; Kalinsky, Kevin; Elias, Anthony D.; Vaklavas, Christos; Beckwith, Heather; Williams, Nicole; Arora, Mili; Nangia, Chaitali; Torres, Evanthia T. Roussos; Thomas, Brittani; Albain, Kathy S.; Clark, Amy S.; Falkson, Carla; Hershman, Dawn L.; Isaacs, Claudine; Thomas, Alexandra; Tseng, Jennifer; Sanford, Amy; Yeung, Kay; Boles, Sarah; Chen, Yunni Yi; Huppert, Laura; Jahan, Nusrat; Parker, Catherine; Giridhar, Karthik; Howard, Frederick M.; Blackwood, M. Michele; Sanft, Tara; Li, Wen; Onishi, Natsuko; Asare, Adam L.; Beineke, Philip; Norwood, Peter; Brown-Swigart, Lamorna; Hirst, Gillian L.; Matthews, Jeffrey B.; Moore, Brian; Symmans, W. Fraser; Price, Elissa; Heditsian, Diane; Lestage, Barbara; Perlmutter, Jane; Pohlmann, Paula; Demichele, Angela; Yee, Douglas; van 't Veer, Laura J.; Hylton, Nola M.; Esserman, Laura J.
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Association between tumor-infiltrating lymphocytes and survival in patients with metastatic breast cancer receiving first-line chemotherapy: analysis of CALGB 40502
errNPJ BREAST CANCER
IF7.6
err2024-08-21
err1
errOAAI
errStover, Daniel G.; Salgado, Roberto; Savenkov, Oleksander; Ballman, Karla; Mayer, Erica L.; Magbanua, Mark Jesus M.; Loi, Sherene; Vater, Mark; Glover, Kristyn; Watson, Mark; Wen, Yujia; Symmans, W. Fraser; Perou, Charles; Carey, Lisa A.; Partridge, Ann H.; Rugo, Hope S.
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Neoadjuvant talazoparib in patients with germline BRCA1/2 mutation-positive, early-stage triple-negative breast cancer: exploration of tumor BRCA mutational status
errBREAST CANCER
IF2.9
err2024-06-13
err7
errOAAI
errTelli, Melinda L.; Litton, Jennifer K.; Beck, J. Thaddeus; Jones, Jason M.; Andersen, Jay; Mina, Lida A.; Brig, Raymond; Danso, Michael; Yuan, Yuan; Symmans, William F.; Hopkins, Julia F.; Albacker, Lee A.; Abbattista, Antonello; Noonan, Kay; Mata, Marielena; Laird, A. Douglas; Blum, Joanne L.
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Phase 2 study of neoadjuvant enzalutamide and paclitaxel for luminal androgen receptor-enriched TNBC: Trial results and insights into ARness ''
errCELL REPORTS MEDICINE
IF10.6
err2024-06-01
err1
errOAAI
errLim, Bora; Seth, Sahil; Yam, Clinton; Huo, Lei; Fujii, Takeo; Lee, Jangsoon; Bassett, Roland; Nasser, Sara; Ravenberg, Lisa; White, Jason; Clayborn, Alyson; Guerra, Gil; Litton, Jennifer K.; Damodaran, Senthil; Layman, Rachel; Valero, Vicente; Tripathy, Debasish; Lewis, Michael; Dobrolecki, Lacey E.; Lei, Jonathan; Candelaria, Rosalind; Arun, Banu; Rauch, Gaiane; Zhao, Li; Zhang, Jianhua; Ding, Qingqing; Symmans, W. Fraser; Chang, Jeffrey T.; Thompson, Alastair M.; Moulder, Stacy L.; Ueno, Naoto T.
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Targeting neddylation and sumoylation in chemoresistant triple negative breast cancer
errNPJ BREAST CANCER
IF7.6
err2024-05-27
err1
errOAAI
errPowell, Reid T.; Rinkenbaugh, Amanda L.; Guo, Lei; Cai, Shirong; Shao, Jiansu; Zhou, Xinhui; Zhang, Xiaomei; Jeter-Jones, Sabrina; Fu, Chunxiao; Qi, Yuan; Hancock, Faiza Baameur; White, Jason B.; Stephan, Clifford; Davies, Peter J.; Moulder, Stacy; Symmans, W. Fraser; Chang, Jeffrey T.; Piwnica-Worms, Helen
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Research Directions

No research directions
Co-authors
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