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Changes in iPSC-astrocyte morphology reflect Alzheimer's disease patient clinical markers Rowland, Helen A.; Miller, Georgina; Liu, Qiang; Li, Shuhan; Sharp, Nicola R.; Ng, Bryan; Wei, Tina; Arunasalam, Kanisa; Koychev, Ivan; Hedegaard, Anne; Ribe, Elena M.; Chan, Dennis; Chessell, Tharani; Kocagoncu, Ece; Lawson, Jennifer; Malhotra, Paresh; Ridha, Basil H.; Rowe, James B.; Thomas, Alan J.; Zamboni, Giovanna; Zetterberg, Henrik; Cader, M. Zameel; Wade-Martins, Richard; Lovestone, Simon; Nevado-Holgado, Alejo; Kormilitzin, Andrey; Buckley, Noel J. Share Save
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Comprehensive characterization of the neurogenic and neuroprotective action of a novel TrkB agonist using mouse and human stem cell models of Alzheimer's disease Charou, Despoina; Rogdakis, Thanasis; Latorrata, Alessia; Valcarcel, Maria; Papadogiannis, Vasileios; Athanasiou, Christina; Tsengenes, Alexandros; Papadopoulou, Maria Anna; Lypitkas, Dimitrios; Lavigne, Matthieu D.; Katsila, Theodora; Wade, Rebecca C.; Cader, M. Zameel; Calogeropoulou, Theodora; Gravanis, Achille; Charalampopoulos, Ioannis Share Save
A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer's disease Tsartsalis, Stergios; Sleven, Hannah; Fancy, Nurun; Wessely, Frank; Smith, Amy M.; Willumsen, Nanet; Cheung, To Ka Dorcas; Rokicki, Michal J.; Chau, Vicky; Ifie, Eseoghene; Khozoie, Combiz; Ansorge, Olaf; Yang, Xin; Jenkyns, Marion H.; Davey, Karen; Mcgarry, Aisling; Muirhead, Robert C. J.; Debette, Stephanie; Jackson, Johanna S.; Montagne, Axel; Owen, David R.; Miners, J. Scott; Love, Seth; Webber, Caleb; Cader, M. Zameel; Matthews, Paul M. Share Save
A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases Al-Thani, Maha; Goodwin-Trotman, Mary; Bell, Steven; Patel, Krushangi; Fleming, Lauren K.; Vilain, Catheline; Abramowicz, Marc; Allan, Stuart M.; Wang, Tao; Cader, M. Zameel; Horsburgh, Karen; Van Agtmael, Tom; Sinha, Sanjay; Markus, Hugh S.; Granata, Alessandra Share Save
Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood-brain barrier Holst, Mikkel Roland; de Wit, Nienke Marije; Ozguer, Burak; Brachner, Andreas; Hyldig, Kathrine; Appelt-Menzel, Antje; Sleven, Hannah; Cader, Zameel; de Vries, Helga Eveline; Neuhaus, Winfried; Jensen, Allan; Brodin, Birger; Nielsen, Morten Schallburg Share Save
Aneuploidy effects on human gene expression across three cell types Liu, Siyuan; Akula, Nirmala; Reardon, Paul K.; Russ, Jill; Torres, Erin; Clasen, Liv S.; Blumenthal, Jonathan; Lalonde, Francois; McMahon, Francis J.; Szele, Francis; Disteche, Christine M.; Cader, M. Zameel; Raznahan, Armin Share Save
Tuberous sclerosis complex-1 (TSC1) contributes to selective neuronal vulnerability in Alzheimer's disease Adriaanse, Bryan A.; Brady, Sinead; Wang, Minghui; Beard, Daniel J.; Spencer, Jonathan I.; Pansieri, Jonathan; Sutherland, Brad A.; Esiri, Margaret M.; Buchan, Alastair M.; Cader, Zameel; Zhang, Bin; DeLuca, Gabriele C. Share Save
Neurons derived from individual early Alzheimer's disease patients reflect their clinical vulnerability Ng, Bryan; Rowland, Helen A.; Wei, Tina; Arunasalam, Kanisa; Hayes, Emma Mee; Koychev, Ivan; Hedegaard, Anne; Ribe, Elena M.; Chan, Dennis; Chessell, Tharani; Ffytche, Dominic; Gunn, Roger N.; Kocagoncu, Ece; Lawson, Jennifer; Malhotra, Paresh A.; Ridha, Basil H.; Rowe, James B.; Thomas, Alan J.; Zamboni, Giovanna; Buckley, Noel J.; Cader, Zameel M.; Lovestone, Simon; Wade-Martins, Richard Share Save
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Genome-Wide Association Study Identifies Risk Loci for Cluster Headache O'Connor, Emer; Fourier, Carmen; Ran, Caroline; Sivakumar, Prasanth; Liesecke, Franziska; Southgate, Laura; Harder, Aster V. E.; Vijfhuizen, Lisanne S.; Yip, Janice; Giffin, Nicola; Silver, Nicholas; Ahmed, Fayyaz; Hostettler, Isabel C.; Davies, Brendan; Cader, M. Zameel; Simpson, Benjamin S.; Sullivan, Roisin; Efthymiou, Stephanie; Adebimpe, Joycee; Quinn, Olivia; Campbell, Ciaran; Cavalleri, Gianpiero L.; Vikelis, Michail; Kelderman, Tim; Paemeleire, Koen; Kilbride, Emer; Grangeon, Lou; Lagrata, Susie; Danno, Daisuke; Trembath, Richard; Wood, Nicholas W.; Kockum, Ingrid; Winsvold, Bendik S.; Steinberg, Anna; Sjostrand, Christina; Waldenlind, Elisabet; Vandrovcova, Jana; Houlden, Henry; Matharu, Manjit; Belin, Andrea Carmine Share Save
Targeted single-cell RNA sequencing of transcription factors enhances the identification of cell types and trajectories Pokhilko, Alexandra; Handel, Adam E.; Curion, Fabiola; Volpato, Viola; Whiteley, Emma S.; Bostrand, Sunniva; Newey, Sarah E.; Akerman, Colin J.; Webber, Caleb; Clark, Michael B.; Bowden, Rory; Cader, M. Zameel Share Save
Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease Pokhilko, Alexandra; Brezzo, Gaia; Handunnetthi, Lahiru; Heilig, Raphael; Lennon, Rachel; Smith, Colin; Allan, Stuart M.; Granata, Alessandra; Sinha, Sanjay; Wang, Tao; Markus, Hugh S.; Naba, Alexandra; Fischer, Roman; Van Agtmael, Tom; Horsburgh, Karen; Cader, M. Zameel Share Save
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Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder Sanghani, Harshmeena R.; Jagannath, Aarti; Humberstone, Thomas; Ebrahimjee, Farid; Thomas, Justyn M.; Churchill, Grant C.; Cipriani, Andrea; Attenburrow, Mary-Jane; Perestenko, Olga, V; Cowley, Sally A.; Cader, M. Zameel; Peirson, Stuart N.; Harrison, Paul J.; Foster, Russell G.; Goodwin, Guy M.; Vasudevan, Sridhar R. Share Save
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