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Philip D. Dunne

patrick g. johnston centre for cancer research

35H-index
521Paper Count
1.3WCitation Count
Published Papers 89
Publication Date
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Immune and stromal tumour biology associated with neoadjuvant radiotherapy response in locally advanced rectal cancer
errBritish Journal of Cancer
IF6.8
err2026-08-18
err0
errOAAI
errLily V. S. Hillson; Ashley K. McCulloch; Ross K. McMahon; Phimmada Hatthakarnkul; Aula Ammar; Timothy S. Maughan; Enric Domingo; Sudhir B. Malla; Raheleh Amirkhah; James H. Park; Joanne Edwards; Philip D. Dunne; Sean M. O’Cathail; Campbell S. Roxburgh
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errSave
Detection of Fusobacterium nucleatum in Colorectal Adenomas Reveals Associations with Immune Molecular Signatures
errInternational Journal of Molecular Sciences
IF4.9
err2026-08-15
err0
errOAAI
errSara Samir Foad Al-Badran; Natalie Fisher; Philip D. Dunne; Mark Johnstone; Noori Maka; William M. Rooney; Samantha Campbell; Paul Capewell; Ditte Andersen; Gerard Lynch; Stephen McSorley; Joanne Edwards
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errSave
Mitochondrial metabolism determines chemotherapy sensitivity in colorectal cancer
errNature Metabolism
IF20.8
err2026-07-23
err0
errOAAI
errDeborah Y. Moss; Connor N. Brown; Andrew M. Shaw; Christopher McCann; Nikita Lewis; Matilda Downs; Rebecca Wurelly; Ciara Cunningham; Aaron Philips; Niamh Doherty; Sarah Gallagher; William J. McDaid; Andrew Roe; Aisling Y. Coughlan; Brenton Cavanagh; Callum Ormsby; Fiammetta Falcone; Rachel McCole; Scott Monteith; Emily Rogan; Sudhir B. Malla; Alexandra J. Emerson; Letitia Mohammed-Smith; Shaun Sharkey; Aoife Leonard; Peter F. Gallagher; Arindam Banerjee; Sandra Van Schaeybroeck; Sufyan Pandor; Brian Quinn; Brett Greer; Christopher Elliott; Sarah Maguire; Aideen E. Ryan; Philip D. Dunne; Mary Mallon; Stephanie Craig; Omar Aftab; Laura C. Greaves; Bryan P. Marzullo; Daniel A. Tennant; Vicky Coyle; Ian G. Mills; Owen Sansom; Tríona Ní Chonghaile; Daniel B. Longley; Simon S. McDade; Melissa J. LaBonte; Emma M. Kerr
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errSave
Viral mimicry redirects immunosuppressed colorectal tumour landscapes towards a proinflammatory and CMS1-like regenerative state
errCommunications Biology
IF5.1
err2026-05-26
err0
errOAAI
errShania M. Corry; Svetlana Sakhnevych; Noha Ehssan Mohamed; Sudhir B. Malla; Ryan Byrne; Andrew Young; Raheleh Amirkhah; Courtney Bull; Andrea Lees; Keara Redmond; Tamsin R. M. Lannagan; Rachel A. Ridgway; Fiona R. Taggart; Natalie C. Fisher; Tim Maughan; Mark Lawler; Andrew D. Campbell; Simon J. Leedham; Aideen E. Ryan; Daniel B. Longley; Donna M. Small; Owen J. Sansom; Philip D. Dunne
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errSave
Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation
errNature Genetics
IF29
err2025-12-18
err0
errOAAI
errGeorgios Kanellos; Chiara Giacomelli; Alexander Raven; Nikola Vlahov; Hu Jin; Pauline Herviou; Sudhir B. Malla; Nadia Nasreddin; Patricia P. Centeno; Constantinos Alexandrou; Kathryn Gilroy; Rachel L. Baird; Kathryn Pennel; June Munro; Joseph A. Waldron; Holly Hall; Leah Officer-Jones; Sheila Bryson; Douglas Strathdee; Sergio Lilla; Sara Zanivan; Vivienne Morrison; Colin Nixon; Rachel A. Ridgway; Crispin Miller; John R. P. Knight; Andrew D. Campbell; Philip D. Dunne; John Le Quesne; Joanne Edwards; Peter J. Park; Martin Bushell; Owen J. Sansom
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errSave
MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance
errNature
IF48.5
err2025-11-24
err0
PREAI
errMark White; Megan L. Mills; Laura M. Millett; Kathryn Gilroy; Yourae Hong; Lucas B. Zeiger; Rosalin J. Simpson; Shania M. Corry; Amelia Ligeza; Tamsin R. M. Lannagan; Susanti Susanti; Rachel A. Ridgway; Ayse S. Yazgili; Lucile Grzesiak; Raheleh Amirkhah; Catriona A. Ford; Nikola Vlahov; Hannah Tovell; Leah Officer-Jones; Catherine Ficken; Rachel Pennie; Arafath K. Najumudeen; Alexander Raven; Nadia Nasreddin; Ekansh Chauhan; Andrew S. Papanastasiou; Colin Nixon; Vivienne Morrison; Rene Jackstadt; Janet S. Graham; Crispin J. Miller; Sarah J. Ross; Simon T. Barry; Valeria Pavet; Richard H. Wilson; John Le Quesne; Philip D. Dunne; Sabine Tejpar; Simon Leedham; Andrew D. Campbell; Owen J. Sansom
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errSave
Identification of a novel GREMLIN1 uptake pathway in epithelial cells that requires BMP binding
errJournal of Biological Chemistry
IF3.9
err2025-09-29
err0
errOAAI
errZhichun Gao; Yuhan Gao; Louise R. Dutton; Melibea Berzosa Suner; Grace Todd; Gregory R. Gipson; Connor Browne; Emma M. Kerr; Carole Daly; Bianca Plouffe; Philip D. Dunne; Dessislava Malinova; Derek P. Brazil
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errSave
Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis
errGUT
IF25.8
err2025-01-29
err1
PREAI
errAl Bakir, Ibrahim; Curtius, Kit; Cresswell, George D.; Grant, Heather E.; Nasreddin, Nadia; Smith, Kane; Nowinski, Salpie; Guo, Qingli; Belnoue-Davis, Hayley L.; Fisher, Jennifer; Clarke, Theo; Kimberley, Christopher; Mossner, Maximilian; Dunne, Philip D.; Loughrey, Maurice B.; Speight, Ally; East, James E.; Wright, Nicholas A.; Rodriguez-Justo, Manuel; Jansen, Marnix; Moorghen, Morgan; Baker, Ann-Marie; Leedham, Simon J.; Hart, Ailsa L.; Graham, Trevor A.
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errSave
Tumour purity assessment with deep learning in colorectal cancer and impact on molecular analysis
errJOURNAL OF PATHOLOGY
IF5.2
err2024-12-22
err0
errOAAI
errSchoenpflug, Lydia A.; Chatzipli, Aikaterini; Sirinukunwattana, Korsuk; Richman, Susan; Blake, Andrew; Robineau, James; Mertz, Kirsten D.; Verrill, Clare; Leedham, Simon J.; Hardy, Claire; Whalley, Celina; Redmond, Keara; Dunne, Philip; Walker, Steven; Beggs, Andrew D.; Mcdermott, Ultan; Murray, Graeme, I; Samuel, Leslie M.; Seymour, Matthew; Tomlinson, Ian; Quirke, Philip; S CORT Consortium, Jens; Rittscher, Jens; Maughan, Tim; Domingo, Enric; Koelzer, Viktor H.
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errSave
Dual gene set enrichment analysis (dualGSEA); an R function that enables more robust biological discovery and pre-clinical model alignment from transcriptomics data
errSCIENTIFIC REPORTS
IF3.9
err2024-12-04
err1
errOAAI
errBull, Courtney; Byrne, Ryan M.; Fisher, Natalie C.; Corry, Shania M.; Amirkhah, Raheleh; Edwards, Jessica; Hillson, Lily V. S.; Lawler, Mark; Ryan, Aideen E.; Lamrock, Felicity; Dunne, Philip D.; Malla, Sudhir B.
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errSave
Identi fi cation and validation of a machine learning model of complete response to radiation in rectal cancer reveals immune in fi ltrate and TGF P as key predictors
errEBIOMEDICINE
IF10.8
err2024-08-01
err1
errOAAI
errDomingo, Enric; Rathee, Sanjay; Blake, Andrew; Samuel, Leslie; Murray, Graeme; Sebag-Montefiore, David; Gollins, Simon; West, Nicholas; Begum, Rubina; Richman, Susan; Quirke, Phil; Redmond, Keara; Chatzipli, Aikaterini; Barberis, Alessandro; Hassanieh, Sylvana; Mahmood, Umair; Youdell, Michael; McDermott, Ultan; Koelzer, Viktor; Leedham, Simon; Tomlinson, Ian; Dunne, Philip; Buffa, Francesca M.; Maughan, Timothy S.
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errSave
Unveiling impaired vascular function and cellular heterogeneity in diabetic donor-derived vascular organoids
errStem Cells
IF3.6
err2024-07-25
err3
errOAAI
errNaderi-Meshkin, Hojjat; Setyaningsih, Wiwit A. Wahyu; Yacoub, Andrew; Carney, Garrett; Cornelius, Victoria A.; Nelson, Clare-Ann; Kelaini, Sophia; Donaghy, Clare; Dunne, Philip D.; Amirkhah, Raheleh; Zampetaki, Anna; Zeng, Lingfang; Stitt, Alan W.; Lois, Noemi; Grieve, David J.; Margariti, Andriana
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errSave
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer (Vol 56, pg 458, 2024)
errNATURE GENETICS
IF31.8
err2024-06-03
err1
errOAAI
errMalla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; McCooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.
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errSave
Image-based consensus molecular subtyping in rectal cancer biopsies and response to neoadjuvant chemoradiotherapy
errNPJ PRECISION ONCOLOGY
IF8
err2024-04-09
err7
errOAAI
errLafarge, Maxime W.; Domingo, Enric; Sirinukunwattana, Korsuk; Wood, Ruby; Samuel, Leslie; Murray, Graeme; Richman, Susan D.; Blake, Andrew; Sebag-Montefiore, David; Gollins, Simon; Klieser, Eckhard; Neureiter, Daniel; Huemer, Florian; Greil, Richard; Dunne, Philip; Quirke, Philip; Weiss, Lukas; Rittscher, Jens; Maughan, Tim; Koelzer, Viktor H.
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errSave
Poor Diagnostic Reproducibility in the Identification of Nonconventional Dysplasia in Colitis Impacts the Application of Histologic Stratification Tools
errMODERN PATHOLOGY
IF5.5
err2024-03-01
err3
errOAAI
errNasreddin, Nadia; Jansen, Marnix; Loughrey, Maurice B.; Wang, Lai Mun; Koelzer, Viktor H.; Rodriguez-Justo, Manuel; Novelli, Marco; Fisher, Jennifer; Brown, Matthew W.; Al Bakir, Ibrahim; Hart, Ailsa L.; Dunne, Philip; Graham, Trevor A.; Leedham, Simon J.
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errSave
Molecular pathological classification of colorectal cancer-an update(feb, 10.1007/s00428-024-03746-3, 2024)
errVIRCHOWS ARCHIV
IF3.1
err2024-02-28
err0
errOAAI
errDunne, Philip D.; Arends, Mark J.
errShare
errSave
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer
errNATURE GENETICS
IF31.8
err2024-02-13
err10
errOAAI
errMalla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; Mccooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.
errShare
errSave
Molecular pathological classification of colorectal cancer-an update
errVIRCHOWS ARCHIV
IF3.1
err2024-02-06
err15
errOAAI
errDunne, Philip D.; Arends, Mark J.
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errSave
Pre-emptive TIPS in high-risk acute variceal bleeding. An updated and revised individual patient data meta-analysis
errHEPATOLOGY
IF15.8
err2023-10-02
err11
PREAI
errNicoara-Farcau, Oana; Han, Guohong; Rudler, Marika; Angrisani, Debora; Monescillo, Alberto; Torres, Ferran; Casanovas, Georgina; Bosch, Jaime; Lv, Yong; Dunne, Philip D. J.; Hayes, Peter C.; Thabut, Dominique; Fan, Daiming; Hernandez-Gea, Virginia; Garcia-Pagan, Juan C.
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PLAC8-Mediated Activation of NOX4 Signalling Restores Angiogenic Function of Endothelial Colony-Forming Cells in Experimental Hypoxia
errCELLS
IF5.2
err2023-09-06
err3
errOAAI
errPun, Shun Hay; O'Neill, Karla M.; Edgar, Kevin S.; Gill, Eleanor K.; Moez, Arya; Naderi-Meshkin, Hojjat; Malla, Sudhir B.; Hookham, Michelle B.; Alsaggaf, Mohammed; Madishetti, Vinuthna Vani; Botezatu, Bianca; King, William; Brunssen, Coy; Morawietz, Henning; Dunne, Philip D.; Brazil, Derek P.; Medina, Reinhold J.; Watson, Chris J.; Grieve, David J.
errShare
errSave

Research Directions

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