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An ALPK3 truncation variant causing autosomal dominant hypertrophic cardiomyopathy is partially rescued by mavacamten Leinhos, Lisa; Robinson, Paul; Poloni, Giulia; Broadway-Stringer, Sophie; Beglov, Julia; Lokman, Adam B.; Douglas, Gillian; Nuthay, Sajjad; Fonseka, Oveena; Schmid, Manuel; Singer, Evie; Hooper, Charlotte; Thomson, Kate; Bagnall, Richard D.; Ingles, Jodie; Semsarian, Christopher; Ormondroyd, Elizabeth; Toepfer, Christopher N.; Davies, Benjamin; Redwood, Charles; Watkins, Hugh; Gehmlich, Katja Share Save
Optimizing approaches for targeted integration of transgenic cassettes by integrase-mediated cassette exchange in mouse and human stem cells Rath, Phalguni; Kramer, Philipp; Biggs, Daniel; Preece, Chris; Hortin, Nicole; Diaz, Rebeca; Perez-Alcantara, Marta; Li, Xiang; Bolard, Arnaud; Beer, Nicola; Mccarthy, Mark; Davies, Benjamin Share Save
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Shieldin and CST co-orchestrate DNA polymerase-dependent tailed-end joining reactions independently of 53BP1-governed repair pathway choice King, Ashleigh; Reichl, Pia I.; Metson, Jean S.; Parker, Robert; Munro, Daniella; Oliveira, Catarina; Sommerova, Lucia; Becker, Jordan R.; Biggs, Daniel; Preece, Chris; Davies, Benjamin; Chapman, J. Ross Share Save
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Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic α-Cells Armour, Sarah L.; Frueh, Alexander; Chibalina, Margarita V.; Dou, Haiqiang; Argemi-Muntadas, Lidia; Hamilton, Alexander; Katzilieris-Petras, Georgios; Carmeliet, Peter; Davies, Benjamin; Moritz, Thomas; Eliasson, Lena; Rorsman, Patrik; Knudsen, Jakob G. Share Save
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Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2 Broadway-Stringer, Sophie; Jiang, He; Wadmore, Kirsty; Hooper, Charlotte; Douglas, Gillian; Steeples, Violetta; Azad, Amar J.; Singer, Evie; Reyat, Jasmeet S.; Galatik, Frantisek; Ehler, Elisabeth; Bennett, Pauline; Kalisch-Smith, Jacinta I.; Sparrow, Duncan B.; Davies, Benjamin; Djinovic-Carugo, Kristina; Gautel, Mathias; Watkins, Hugh; Gehmlich, Katja Share Save
Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression Mattis, Katia K.; Krentz, Nicole A. J.; Metzendorf, Christoph; Abaitua, Fernando; Spigelman, Aliya F.; Sun, Han; Ikle, Jennifer M.; Thaman, Swaraj; Rottner, Antje K.; Bautista, Austin; Mazzaferro, Eugenia; Perez-Alcantara, Marta; Fox, Jocelyn E. Manning E.; Torres, Jason M.; Wesolowska-Andersen, Agata; Yu, Grace Z. Z.; Mahajan, Anubha; Larsson, Anders; MacDonald, Patrick E.; Davies, Benjamin; den Hoed, Marcel; Gloyn, Anna L. Share Save
NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance Hodgson, Rose; Xu, Xijin; Anzilotti, Consuelo; Deobagkar-Lele, Mukta; Crockford, Tanya L.; Kepple, Jessica D.; Cawthorne, Eleanor; Bhandari, Aneesha; Cebrian-Serrano, Alberto; Wilcock, Martin J.; Davies, Benjamin; Cornall, Richard J.; Bull, Katherine R. Share Save
Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance Zhang, Ping; Amarasinghe, Harindra E.; Whalley, Justin P.; Tay, Chwen; Fang, Hai; Migliorini, Gabriele; Brown, Andrew C.; Allcock, Alice; Scozzafava, Giuseppe; Rath, Phalguni; Davies, Benjamin; Knight, Julian C. Share Save
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Altering the Binding Properties of PRDM9 Partially Restores Fertility across the Species Boundary Davies, Benjamin; Gupta Hinch, Anjali; Cebrian-Serrano, Alberto; Alghadban, Samy; Becker, Philipp W.; Biggs, Daniel; Hernandez-Pliego, Polinka; Preece, Chris; Moralli, Daniela; Zhang, Gang; Myers, Simon; Donnelly, Peter Share Save
When the genome bluffs: a tandem duplication event during generation of a novel Agmo knockout mouse model fools routine genotyping Sailer, Sabrina; Coassin, Stefan; Lackner, Katharina; Fischer, Caroline; McNeill, Eileen; Streiter, Gertraud; Kremser, Christian; Maglione, Manuel; Green, Catherine M.; Moralli, Daniela; Moschen, Alexander R.; Keller, Markus A.; Golderer, Georg; Werner-Felmayer, Gabriele; Tegeder, Irmgard; Channon, Keith M.; Davies, Benjamin; Werner, Ernst R.; Watschinger, Katrin Share Save
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