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Gene Editing and Small Molecule Inhibitors of the RNA Binding Protein IGF2BP2/IMP2 Show its Potential as an Anti-Cancer Drug Target Chanda, Shilpee; Lepikhov, Konstantin; Dahlem, Charlotte; Schymik, Hanna S.; Hoppstaedter, Jessica; Geber, An-Kristin; Wagner, Konrad; Kessler, Sonja M.; Empting, Martin; Kiemer, Alexandra K. Share Save
RNA binding protein IGF2BP2 expression is induced by stress in the heart and mediates dilated cardiomyopathy Krumbein, Miriam; Oberman, Froma; Cinnamon, Yuval; Golomb, Mordechai; May, Dalit; Vainer, Gilad; Belzer, Vitali; Meir, Karen; Fridman, Irina; Haybaeck, Johannes; Poelzl, Gerhard; Kehat, Izhak; Beeri, Ronen; Kessler, Sonja M.; Yisraeli, Joel K. Share Save
Alterations in the hepatocyte epigenetic landscape in steatosis Maji, Ranjan Kumar; Czepukojc, Beate; Scherer, Michael; Tierling, Sascha; Cadenas, Cristina; Gianmoena, Kathrin; Gasparoni, Nina; Nordstroem, Karl; Gasparoni, Gilles; Laggai, Stephan; Yang, Xinyi; Sinha, Anupam; Ebert, Peter; Falk-Paulsen, Maren; Kinkley, Sarah; Hoppstaedter, Jessica; Chung, Ho-Ryun; Rosenstiel, Philip; Hengstler, Jan G.; Walter, Joern; Schulz, Marcel H.; Kessler, Sonja M.; Kiemer, Alexandra K. Share Save
A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer Kendzia, Sandra; Franke, Susanne; Kroehler, Tarek; Golob-Schwarzl, Nicole; Schweiger, Caroline; Toeglhofer, Anna M.; Skofler, Christina; Uranitsch, Stefan; El-Heliebi, Amin; Fuchs, Julia; Punschart, Andreas; Stiegler, Philipp; Keil, Marlen; Hoffmann, Jens; Henderson, David; Lehrach, Hans; Yaspo, Marie-Laure; Reinhard, Christoph; Schaefer, Reinhold; Keilholz, Ulrich; Regenbrecht, Christian; Schicho, Rudolf; Fickert, Peter; Lax, Sigurd F.; Erdmann, Frank; Schulz, Marcel H.; Kiemer, Alexandra K.; Haybaeck, Johannes; Kessler, Sonja M. Share Save
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First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy Dahlem, Charlotte; Abuhaliema, Ali; Kessler, Sonja M.; Kroehler, Tarek; Zoller, Ben G. E.; Chanda, Shilpee; Wu, Yingwen; Both, Simon; Mueller, Fabian; Lepikhov, Konstantin; Kirsch, Susanne H.; Laggai, Stephan; Muller, Rolf; Empting, Martin; Kiemer, Alexandra K. Share Save
CRUP: a comprehensive framework to predict condition-specific regulatory units Ramisch, Anna; Heinrich, Verena; Glaser, Laura V.; Fuchs, Alisa; Yang, Xinyi; Benner, Philipp; Schoepflin, Robert; Li, Na; Kinkley, Sarah; Roemer-Hillmann, Anja; Longinotto, John; Heyne, Steffen; Czepukojc, Beate; Kessler, Sonja M.; Kiemer, Alexandra K.; Cadenas, Cristina; Arrigoni, Laura; Gasparoni, Nina; Manke, Thomas; Pap, Thomas; Pospisilik, John A.; Hengstler, Jan; Walter, Joern; Meijsing, Sebastiaan H.; Chung, Ho-Ryun; Vingron, Martin Share Save
IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis Czepukojc, Beate; Abuhaliema, Ali; Barghash, Ahmad; Tierling, Sascha; Nass, Norbert; Simon, Yvette; Koerbel, Christina; Cadenas, Cristina; van Hul, Noemi; Sachinidis, Agapios; Hengstler, Jan G.; Helms, Volkhard; Laschke, Matthias W.; Walter, Joern; Haybaeck, Johannes; Leclercq, Isabelle; Kiemer, Alexandra K.; Kessler, Sonja M. Share Save
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The mRNA-binding protein tristetraprolin promotes hepatocarcinogenesis but inhibits tumour progression in liver cancer Kessler, Sonja; Hosseini, Kevan; Kroehler, Tarek; Barghash, Ahmad; Patial, Sonika; Hoppstaedter, Jessica; Gemperlein, Katja; Haybaeck, Johannes; List, Markus; Mueller, Rolf; Helms, Volkhard; Schulz, Marcel; Laggai, Stephan; Blackshear, Perry; Kiemer, Alexandra K. Share Save
Hsp72 protects against liver injury via attenuation of hepatocellular death, oxidative stress, and JNK signaling Levada, Kateryna; Guldiken, Nurdan; Zhang, Xiaoji; Vella, Giovanna; Mo, Fa-Rong; James, Laura P.; Haybaeck, Johannes; Kessler, Sonja M.; Kiemer, Alexandra K.; Ott, Thomas; Hartmann, Daniel; Hueser, Norbert; Ziol, Marianne; Trautwein, Christian; Strnad, Pavel Share Save
Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice Themanns, Madeleine; Mueller, Kristina M.; Kessler, Sonja M.; Golob-Schwarzl, Nicole; Mohr, Thomas; Kaltenecker, Doris; Bourgeais, Jerome; Paier-Pourani, Jamile; Friedbichler, Katrin; Schneller, Doris; Schlederer, Michaela; Zebedin-Brandl, Eva; Terracciano, Luigi M.; Han, Xiaonan; Kenner, Lukas; Wagner, Kay-Uwe; Mikulits, Wolfgang; Kozlov, Andrey V.; Heim, Markus H.; Gouilleux, Fabrice; Haybaeck, Johannes; Moriggl, Richard Share Save
Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation (vol 7, 147, 2016) Kessler, Sonja M.; Laggai, Stephan; Van Wonterghem, Ellen; Gemperlein, Katja; Mueller, Rolf; Haybaeck, Johannes; Vandenbroucke, Roosmarijn E.; Ogris, Manfred; Libert, Claude; Kiemer, Alexandra K. Share Save
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Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation Kessler, Sonja M.; Laggai, Stephan; Van Wonterghem, Elien; Gemperlein, Katja; Mueller, Rolf; Haybaeck, Johannes; Vandenbroucke, Roosmarijn E.; Ogris, Manfred; Libert, Claude; Kiemer, Alexandra K. Share Save
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