Not logged in A human histidyl-tRNA synthetase splice variant therapeutic targets NRP2 to resolve lung inflammation and fibrosis Nangle, Leslie A.; Xu, Zhiwen; Siefker, David; Burkart, Christoph; Chong, Yeeting E.; Zhai, Liting; Geng, Yanyan; Polizzi, Clara; Guy, Lauren; Eide, Lisa; Tong, Yao; Klopp-Savino, Sofia; Ferrer, Michaela; Rauch, Kaitlyn; Wang, Annie; Hamel, Kristina; Crampton, Steve; Paz, Suzanne; Chiang, Kyle P.; Do, Minh-Ha; Burman, Luke; Lee, Darin; Zhang, Mingjie; Ogilvie, Kathleen; King, David; Adams, Ryan A.; Schimmel, Paul Share Save
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Clinical and molecular characterization of novel FARS2 variants causing neonatal mitochondrial disease Chen, Wenqian; Rehsi, Preeya; Thompson, Kyle; Yeo, Mildrid; Stals, Karen; He, Langping; Schimmel, Paul; Chrzanowska-Lightowlers, Zofia M. A.; Wakeling, Emma; Taylor, Robert W.; Kuhle, Bernhard Share Save
Domain collapse and active site ablation generate a widespread animal mitochondrial seryl-tRNA synthetase de Potter, Bastiaan; Vallee, Ingrid; Camacho, Noelia; Povoas, Luis Filipe Costa; Bonsembiante, Aureliano; Pons i Pons, Alba; Eckhard, Ulrich; Gomis-Ruth, Francesc-Xavier; Yang, Xiang-Lei; Schimmel, Paul; Kuhle, Bernhard; Ribas de Pouplana, Lluis Share Save
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Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2 (vol 25, pg 592, 2023) Cui, Haissi; Diedrich, Jolene K.; Wu, Douglas C.; Lim, Justin J.; Nottingham, Ryan M.; Moresco, James J.; Yates III, John R.; Blencowe, Benjamin J.; Lambowitz, Alan M.; Schimmel, Paul Share Save
Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2 Cui, Haissi; Diedrich, Jolene K.; Wu, Douglas C.; Lim, Justin J.; Nottingham, Ryan M.; Moresco, James J.; Yates, John R.; Blencowe, Benjamin J.; Lambowitz, Alan M.; Schimmel, Paul Share Save
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target Istvan, Eva S.; Guerra, Francisco; Abraham, Matthew; Huang, Kuo-Sen; Rocamora, Frances; Zhao, Haoshuang; Xu, Lan; Pasaje, Charisse; Kumpornsin, Krittikorn; Luth, Madeline R.; Cui, Haissi; Yang, Tuo; Diaz, Sara Palomo; Gomez-Lorenzo, Maria G.; Qahash, Tarrick; Mittal, Nimisha; Ottilie, Sabine; Niles, Jacquin; Lee, Marcus C. S.; Llinas, Manue; Kato, Nobutaka; Okombo, John; Fidock, David A.; Schimmel, Paul; Gamo, Francisco Javier; Goldberg, Daniel E.; Winzeler, Elizabeth A. Share Save
The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements Han, Lu; Luo, Zhiteng; Ju, Yingchen; Chen, Bingyi; Zou, Taotao; Wang, Junjian; Xu, Jun; Gu, Qiong; Yang, Xiang-Lei; Schimmel, Paul; Zhou, Huihao Share Save
Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral infection Morodomi, Yosuke; Kanaji, Sachiko; Sullivan, Brian M.; Zarpellon, Alessandro; Orje, Jennifer N.; Won, Eric; Shapiro, Ryan; Yang, Xiang-Lei; Ruf, Wolfram; Schimmel, Paul; Ruggeri, Zaverio M.; Kanaji, Taisuke Share Save
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PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications (vol 23, pg 424, 2021) Shi, Junchao; Zhang, Yunfang; Tan, Dongmei; Zhang, Xudong; Yan, Menghong; Zhang, Ying; Franklin, Reuben; Shahbazi, Marta; Mackinlay, Kirsty; Liu, Shichao; Kuhle, Bernhard; James, Emma R.; Zhang, Liwen; Qu, Yongcun; Zhai, Qiwei; Zhao, Wenxin; Zhao, Linlin; Zhou, Changcheng; Gu, Weifeng; Murn, Jernej; Guo, Jingtao; Carrell, Douglas T.; Wang, Yinsheng; Chen, Xuemei; Cairns, Bradley R.; Yang, Xiang-lei; Schimmel, Paul; Zernicka-Goetz, Magdalena; Cheloufi, Sihem; Zhang, Ying; Zhou, Tong; Chen, Qi Share Save
PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications Shi, Junchao; Zhang, Yunfang; Tan, Dongmei; Zhang, Xudong; Yan, Menghong; Zhang, Ying; Franklin, Reuben; Shahbazi, Marta; Mackinlay, Kirsty; Liu, Shichao; Kuhle, Bernhard; James, Emma R.; Zhang, Liwen; Qu, Yongcun; Zhai, Qiwei; Zhao, Wenxin; Zhao, Linlin; Zhou, Changcheng; Gu, Weifeng; Murn, Jernej; Guo, Jingtao; Carrell, Douglas T.; Wang, Yinsheng; Chen, Xuemei; Cairns, Bradley R.; Yang, Xiang-lei; Schimmel, Paul; Zernicka-Goetz, Magdalena; Cheloufi, Sihem; Zhang, Ying; Zhou, Tong; Chen, Qi Share Save
CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS Sun, Litao; Wei, Na; Kuhle, Bernhard; Blocquel, David; Novick, Scott; Matuszek, Zaneta; Zhou, Huihao; He, Weiwei; Zhang, Jingjing; Weber, Thomas; Horvath, Rita; Latour, Philippe; Pan, Tao; Schimmel, Paul; Griffin, Patrick R.; Yang, Xiang-Lei Share Save
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Extracellular tyrosyl-tRNA synthetase cleaved by plasma proteinases and stored in platelet α-granules: Potential role in monocyte activation Won, Eric; Morodomi, Yosuke; Kanaji, Sachiko; Shapiro, Ryan; Vo, My-Nuong; Orje, Jennifer N.; Thornburg, Courtney D.; Yang, Xiang-Lei; Ruggeri, Zaverio M.; Schimmel, Paul; Kanaji, Taisuke Share Save
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CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells Blocquel, David; Sun, Litao; Matuszekc, Zaneta; Li, Sheng; Weber, Thomas; Kuhle, Bernhard; Kooi, Grace; Wei, Na; Baets, Jonathan; Pan, Tao; Schimmel, Paul; Yang, Xiang-Lei Share Save
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