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Xuankuo Xu

Bristol Myers Squibb

18H-index
70Paper Count
1.0KCitation Count
Published Papers 48
Publication Date
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Modernizing the platform process of antibody purification for enhanced impurity clearance
errSeparation and Purification Technology
IF9
err2025-11-17
err0
errOAAI
errJacob LeBarre; Dipendra Bhandari; Eduardo Barbieri; Qingbo Shu; Xuanwen Li; Divya Chandra; Xuankuo Xu; Michael Phillips; Jerome Bill; Taufika Williams; Patrick Gilbert; Christopher Major; David Roush; Steven Cramer; Abraham Lenhoff; Cristiana Boi; Ruben Carbonell; Stefano Menegatti
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Hydrophobicity analysis of Chinese Hamster Ovary host cell proteins using analytical hydrophobic interaction chromatography and LC-MS
errJournal of Chromatography A
IF4
err2025-10-04
err0
PREAI
errLiang-Kai Chu; Tatiana Laremore; Ehsan Espah Borujeni; Xuankuo Xu; Andrew Zydney
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errSave
Flow-through polishing of Protein A eluates: Removal of high and low molecular weight impurities by size-exclusion-mixed-mode chromatography
errJournal of Chromatography A
IF4
err2025-09-12
err0
PREAI
errJacob P. LeBarre; Wenning Chu; Ka Zhang; Dipendra Bhandari; Cristiana Boi; Ruben Carbonell; Xuanwen Li; Divya Chandra; Ronald Maurer; Xuankuo Xu; Jerome Bill; David Roush; Michael Phillips; Stefano Menegatti
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errSave
Use of LC-MS to characterize host cell protein removal during depth filtration
errBIOTECHNOLOGY PROGRESS
IF2.5
err2025-05-23
err0
errOAAI
errLiang-Kai Chu; Ehsan Espah Borujeni; Xuankuo Xu; Andrew L. Zydney
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errSave
Modeling and techno-economic analysis of downstream manufacturing process intensification strategies for existing biopharmaceutical facilities
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2024-11-01
err0
PREAI
errRomero, Juan J.; Angelo, James; Xu, Xuankuo; Husson, Scott M.; Ghose, Sanchayita
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Predictive mechanistic modeling of loading and elution in protein A chromatography
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2024-01-01
err5
PREAI
errBhoyar, Soumitra; Kumar, Vijesh; Foster, Max; Xu, Xuankuo; Traylor, Steven J.; Guo, Jing; Lenhoff, Abraham M.
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errSave
Behavior of host-cell-protein-rich aggregates in antibody capture and polishing chromatography
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2023-08-01
err8
PREAI
errHerman, Chase E.; Min, Lie; Choe, Leila H.; Maurer, Ronald W.; Xu, Xuankuo; Ghose, Sanchayita; Lee, Kelvin H.; Lenhoff, Abraham M.
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errSave
Engineering protein A ligands to mitigate antibody loss during high-pH washes in protein A chromatography
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2023-05-01
err4
PREAI
errBhoyar, Soumitra; Foster, Max; Oh, Young Hoon; Xu, Xuankuo; Traylor, Steven J.; Guo, Jing; Ghose, Sanchayita; Lenhoff, Abraham M.
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errSave
Comparison of host cell protein removal by depth filters with diatomaceous earth and synthetic silica filter aids using model proteins
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2023-03-31
err3
errOAAI
errChu, Liang-Kai; Borujeni, Ehsan Espah; Xu, Xuankuo; Ghose, Sanchayita; Zydney, Andrew L.
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errSave
Role of the gradient slope during the product internal recycling for the multicolumn countercurrent solvent gradient purification of PEGylated proteins
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2023-03-01
err5
errOAAI
errKim, Tae Keun; Bham, Abdallah Ayub; Fioretti, Ismaele; Angelo, James; Xu, Xuankuo; Ghose, Sanchayita; Morbidelli, Massimo; Sponchioni, Mattia
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errSave
Effect of solution condition on the binding behaviors of monoclonal antibody and fusion protein therapeutics in Protein A chromatography
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2022-12-01
err7
PREAI
errGuo, Jing; Noyes, Steven; Jin, Weixin; Curtis, Harris; Xu, Xuankuo; Ghose, Sanchayita
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errSave
Design and economic investigation of a Multicolumn Countercurrent Solvent Gradient Purification unit for the separation of an industrially relevant PEGylated protein
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2022-10-01
err7
PREAI
errKim, Tae Keun; Sechi, Benedetta; Conde, Juan Jose Romero; Angelo, James; Xu, Xuankuo; Ghose, Sanchayita; Morbidelli, Massimo; Sponchioni, Mattia
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errSave
Behavior of weakly adsorbing protein impurities in flow-through ion-exchange chromatography
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2022-02-01
err5
PREAI
errHerman, Chase E.; Xu, Xuankuo; Traylor, Steven J.; Ghose, Sanchayita; Li, Zheng Jian; Lenhoff, Abraham M.
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errSave
Virus inactivation at moderately low pH varies with virus and buffer properties
errBIOTECHNOLOGY JOURNAL
IF3.1
err2021-12-23
err8
PREAI
errJoshi, Pratik U.; Meingast, Christa L.; Xu, Xuankuo; Holstein, Melissa; Feroz, Hasin; Ranjan, Swarnim; Ghose, Sanchayita; Li, Zheng Jian; Heldt, Caryn L.
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errSave
Untargeted proteomics reveals upregulation of stress response pathways during CHO-based monoclonal antibody manufacturing process leading to disulfide bond reduction
errMABS
IF7.3
err2021-08-23
err6
errOAAI
errPark, Seo-Young; Egan, Susan; Cura, Anthony J.; Aron, Kathryn L.; Xu, Xuankuo; Zheng, Mengyuan; Borys, Michael; Ghose, Sanchayita; Li, Zhengjian; Lee, Kyongbum
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errSave
Experimental Design of the Multicolumn Countercurrent Solvent Gradient Purification (MCSGP) Unit for the Separation of PEGylated Proteins
errINDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
IF3.9
err2021-06-10
err15
errOAAI
errKim, Tae Keun; Botti, Chiara; Angelo, James; Xu, Xuankuo; Ghose, Sanchayita; Li, Zheng Jian; Morbidelli, Massimo; Sponchioni, Mattia
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errSave
Physiochemical properties of enveloped viruses and arginine dictate inactivation
errBIOTECHNOLOGY JOURNAL
IF3.1
err2021-05-13
err10
PREAI
errMeingast, Christa L.; Joshi, Pratik U.; Turpeinen, Dylan G.; Xu, Xuankuo; Holstein, Melissa; Feroz, Hasin; Ranjan, Swarnim; Ghose, Sanchayita; Li, Zheng Jian; Heldt, Caryn L.
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errSave
Productivity improvement and charge variant modulation for intensified cell culture processes by adding a carboxypeptidase B (CpB) treatment step
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2021-03-11
err4
PREAI
errXu, Jianlin; Zheng, Shun; Dawood, Zeinab; Hill, Charles; Jin, Weixin; Xu, Xuankuo; Ding, Julia; Borys, Michael C.; Ghose, Sanchayita; Li, Zheng Jian; Pendse, Girish
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Continued insights into virus clearance validation across continuous capture chromatography
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2021-01-21
err5
PREAI
errAngelo, James M.; Potter, Kevin; Muller-Spath, Thomas; Xu, Xuankuo; Li, Zheng Jian; Ghose, Sanchayita
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errSave
Hydrophobic property of cation-exchange resins affects monoclonal antibody aggregation
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2020-11-01
err6
PREAI
errHuang, Chao; Wang, Yiran; Xu, Xuankuo; Mills, Jason; Jin, Weixin; Ghose, Sanchayita; Li, Zheng Jian
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
E
Ernesto Freire
H-index: 89 · Papers: 295
M
Massimo Morbidelli
H-index: 86 · Papers: 857
Y
Yan Yao
H-index: 86 · Papers: 599
W
Wilfred Chen
H-index: 76 · Papers: 342
N
Norman J. Wagner
H-index: 76 · Papers: 539
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