arrow
Back
S

Siegfried Labeit

University of Heidelberg

90H-index
356Paper Count
2.6WCitation Count
Published Papers 128
Publication Date
MyoMed205 Counteracts Titin Hyperphosphorylation and the Expression of Contraction-Regulating Proteins in a Rat Model of HFpEF
err2025-06-04
err0
errOAAI
errBeatrice Vahle; Antje Schauer; Antje Augstein; Maria-Elisa Prieto Jarabo; Janet Friedrich; Peggy Barthel; Anita Männel; Norman Mangner; Siegfried Labeit
errShare
errSave
Leucine Supplementation Counteracts the Atrophic Effects of HDAC4 in Rat Skeletal Muscle Submitted to Hindlimb Immobilization
err2025-04-04
err0
errOAAI
errPaula K. N. Alves; André Cruz; William J. Silva; Afonso M. Melazzo; Siegfried Labeit; Volker Adams; Anselmo S. Moriscot
errShare
errSave
Small-molecule mediated MuRF1 inhibition protects from doxorubicin-induced cardiac atrophy and contractile dysfunction
err2024-12-01
err0
errOAAI
errAlves, Paula K. N.; Cruz, Andre; Adams, Volker; Moriscot, Anselmo S.; Labeit, Siegfried
errShare
errSave
Truncated titin is structurally integrated into the human dilated cardiomyopathic sarcomere
err2024-01-16
err4
errOAAI
errKellermayer, Dalma; Tordai, Hedvig; Kiss, Balazs; Torok, Gyorgy; Peter, Daniel M.; Sayour, Alex Ali; Polos, Miklos; Hartyanszky, Istvan; Szilveszter, Balint; Labeit, Siegfried; Gango, Ambrus; Bedics, Gabor; Bodor, Csaba; Radovits, Tamas; Merkely, Bela; Kellermayer, Miklos S. Z.
errShare
errSave
Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis
err2023-02-03
err4
errOAAI
errStergiou, Christos; Williams, Rhys; Fleming, Jennifer R. R.; Zouvelou, Vasiliki; Ninou, Elpinickie; Andreetta, Francesca; Rinaldi, Elena; Simoncini, Ornella; Mantegazza, Renato; Bogomolovas, Julius; Tzartos, John; Labeit, Siegfried; Mayans, Olga; Tzartos, Socrates
errShare
errSave
errShare
errSave
The skeletal muscle circadian clock regulates titin splicing through RBM20
err2022-09-01
err10
errOAAI
errRiley, Lance A.; Zhang, Xiping; Douglas, Collin M.; Mijares, Joseph M.; Hammers, David W.; Wolff, Christopher A.; Wood, Neil B.; Olafson, Hailey R.; Du, Ping; Labeit, Siegfried; Previs, Michael J.; Wang, Eric T.; Esser, Karyn A.
errShare
errSave
Targeting MuRF1 by small molecules in a HFpEF rat model improves myocardial diastolic function and skeletal muscle contractility
err2022-03-17
err32
errOAAI
errAdams, Volker; Schauer, Antje; Augstein, Antje; Kirchhoff, Virginia; Draskowski, Runa; Jannasch, Anett; Goto, Keita; Lyall, Gemma; Maennel, Anita; Barthel, Peggy; Mangner, Norman; Winzer, Ephraim B.; Linke, Axel; Labeit, Siegfried
errShare
errSave
Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere
err2021-08-17
err24
errOAAI
errBogomolovas, Julius; Fleming, Jennifer R.; Franke, Barbara; Manso, Bruno; Simon, Bernd; Gasch, Alexander; Markovic, Marija; Brunner, Thomas; Knoll, Ralph; Chen, Ju; Labeit, Siegfried; Scheffner, Martin; Peter, Christine; Mayans, Olga
errShare
errSave
Muscle ankyrin repeat protein 1 (MARP1) locks titin to the sarcomeric thin filament and is a passive force regulator
err2021-06-21
err25
errOAAI
errvan der Pijl, Robbert J.; van den Berg, Marloes; van de Locht, Martijn; Shen, Shengyi; Bogaards, Sylvia J. P.; Conijn, Stefan; Langlais, Paul; Hooijman, Pleuni E.; Labeit, Siegfried; Heunks, Leo M. A.; Granzier, Henk; Ottenheijm, Coen A. C.
errShare
errSave
Leucine Supplementation Decreases HDAC4 Expression and Nuclear Localization in Skeletal Muscle Fiber of Rats Submitted to Hindlimb Immobilization
errCELLS
IF5.2
err2020-12-02
err7
errOAAI
errAlves, Paula K. N.; Cruz, Andre; Silva, William J.; Labeit, Siegfried; Moriscot, Anselmo S.
errShare
errSave
Small-Molecule Chemical Knockdown of MuRF1 in Melanoma Bearing Mice Attenuates Tumor Cachexia Associated Myopathy
errCELLS
IF5.2
err2020-10-11
err22
errOAAI
errAdams, Volker; Gussen, Victoria; Zozulya, Sergey; Cruz, Andre; Moriscot, Anselmo; Linke, Axel; Labeit, Siegfried
errShare
errSave
ZSF1 rat as animal model for HFpEF: Development of reduced diastolic function and skeletal muscle dysfunction
err2020-07-25
err46
errOAAI
errSchauer, Antje; Draskowski, Runa; Jannasch, Anett; Kirchhoff, Virginia; Goto, Keita; Maennel, Anita; Barthel, Peggy; Augstein, Antje; Winzer, Ephraim; Tugtekin, Malte; Labeit, Siegfried; Linke, Axel; Adams, Volker
errShare
errSave
Small-molecule-mediated chemical knock-down of MuRF1/MuRF2 and attenuation of diaphragm dysfunction in chronic heart failure
err2019-05-29
err41
errOAAI
errAdams, Volker; Bowen, T. Scott; Werner, Sarah; Barthel, Peggy; Amberger, Christina; Konzer, Anne; Graumann, Johannes; Sehr, Peter; Lewis, Joe; Provaznik, Jan; Benes, Vladimir; Buettner, Petra; Gasch, Alexander; Mangner, Norman; Witt, Christian C.; Labeit, Dittmar; Linke, Axel; Labeit, Siegfried
errShare
errSave
miR-29c improves skeletal muscle mass and function throughout myocyte proliferation and differentiation and by repressing atrophy-related genes
err2019-05-03
err47
errOAAI
errSilva, William Jose; Graca, Flavia Aparecida; Cruz, Andre; Silvestre, Joao Guilherme; Labeit, Siegfried; Miyabara, Elen Haruka; Yan, Chao Yun Irene; Wang, Da Zhi; Moriscot, Anselmo Sigari
errShare
errSave
Refined localisation of the genes for nebulin and titin on chromosome 2q allows the assignment of nebulin as a candidate gene for autosomal recessive nemaline myopathy
err2019-02-19
err31
PREAI
errPelin, K; Ridanpaa, M; Donner, K; Wilton, S; Krishnarajah, J; Laing, N; Kolmerer, B; Millevoi, S; Labeit, S; delaChapelle, A; WallgrenPetterson, C
errShare
errSave
Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients
err2019-01-01
err13
errOAAI
errHigashikuse, Yuta; Mittal, Nishant; Arimura, Takuro; Yoon, Sung Han; Oda, Mayumi; Enomoto, Hirokazu; Kaneda, Ruri; Hattori, Fumiyuki; Suzuki, Takeshi; Kawakami, Atsushi; Gasch, Alexander; Furukawa, Tetsushi; Labeit, Siegfried; Fukuda, Keiichi; Kimura, Akinori; Makino, Shinji
errShare
errSave
Titin-based mechanosensing modulates muscle hypertrophy
err2018-07-05
err45
errOAAI
errvan der Pijl, Robbert; Strom, Joshua; Conijn, Stefan; Lindqvist, Johan; Labeit, Siegfried; Granzier, Henk; Ottenheijm, Coen
errShare
errSave
The giant protein titin regulates the length of the striated muscle thick filament
err2017-10-19
err92
errOAAI
errTonino, Paola; Kiss, Balazs; Strom, Josh; Methawasin, Mei; Smith, John E., III; Kolb, Justin; Labeit, Siegfried; Granzier, Henk
errShare
errSave