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SaveLacking ARHGAP25 mitigates the symptoms of autoantibody-induced arthritis in mice
Czaran, Domonkos; Sasvari, Peter; Horvath, Adam Istvan; Ella, Krisztina; Sudy, Agnes Reka; Borbely, Eva; Rusznak, Kitti; Czeh, Boldizsar; Mocsai, Attila; Helyes, Zsuzsanna; Csepanyi-Komi, Roland Share Save Share Save The heptapeptide somatostatin analogue TT-232 exerts analgesic and anti-inflammatory actions via SST4 receptor activation: In silico, in vitro and in vivo evidence in miceBorzsei, Rita; Borbely, Eva; Kantas, Boglarka; Hudhud, Lina; Horvath, Adam; Szoke, Eva; Hetenyi, Csaba; Helyes, Zsuzsanna; Pinter, Erika Share Save Share Save Share Save Interaction of SZV 1287, a novel oxime analgesic drug candidate, and its metabolites with serum albuminFliszar-Nyul, Eszter; Faisal, Zelma; Mohos, Violetta; Derdak, Diana; Lemli, Beata; Kalai, Tamas; Sar, Cecilia; Zsido, Balazs Z.; Hetenyi, Csaba; Horvath, Adam, I; Helyes, Zsuzsanna; Deme, Ruth; Bogdan, Dora; Czompa, Andrea; Matyus, Peter; Poor, Miklos Share Save Proof-of-Concept for the Analgesic Effect and Thermoregulatory Safety of Orally Administered Multi-Target Compound SZV 1287 in Mice: A Novel Drug Candidate for Neuropathic PainHorvath, Adam Istvan; Szentes, Nikolett; Tekus, Valeria; Payrits, Maja; Szoke, Eva; Olah, Emoke; Garami, Andras; Fliszar-Nyul, Eszter; Poor, Miklos; Sar, Cecilia; Kalai, Tamas; Pal, Szilard; Percze, Krisztina; Scholz, Eva Nagyne; Meszaros, Tamas; Toth, Blanka; Matyus, Peter; Helyes, Zsuzsanna Share Save Protective effects of the novel amine-oxidase inhibitor multi-target drug SZV 1287 on streptozotocin-induced beta cell damage and diabetic complications in ratsTekus, Valeria; Horvath, Adam Istvan; Cseko, Kata; Szabadfi, Krisztina; Kovacs-Valasek, Andrea; Danyadi, Bese; Deres, Laszlo; Halmosi, Robert; Saghy, Eva; Varga, Zoltan V.; Adeghate, Ernest; Koszegi, Tamas; Matyus, Peter; Gabriel, Robert; Ferdinandy, Peter; Pinter, Erika; Helyes, Zsuzsanna Share Save Radiosynthesis and Preclinical Investigation of11C-Labelled 3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanal Oxime ([11C]SZV 1287)Forgacs, Viktoria; Nemeth, Eniko; Gyuricza, Barbara; Kis, Adrienn; Szabo, Judit P.; Mikecz, Pal; Matyus, Peter; Helyes, Zsuzsanna; Horvath, Adam Istvan; Kalai, Tamas; Trencsenyi, Gyorgy; Fekete, Aniko; Szikra, Dezso Share Save Antinociceptive Effects of Lipid Raft Disruptors, a Novel Carboxamido-Steroid and Methyl β-Cyclodextrin, in Mice by Inhibiting Transient Receptor Potential Vanilloid 1 and Ankyrin 1 Channel ActivationHorvath, Adam; Biro-Suto, Tunde; Kantas, Boglarka; Payrits, Maja; Skoda-Foldes, Rita; Szanti-Pinter, Eszter; Helyes, Zsuzsanna; Szoke, Eva Share Save Share Save Expression and Protective Functions of the sst4 Somatostatin Receptor in the Indomethacin-Induced Gastrointestinal Mucosal Injury Model of the MouseHelyes, Zsuzsanna; Csekoe, Kata; Kormos, Viktoria; Zelena, Dora; Iarushkina, Natalia; Sudalina, Maria; Horvath, Adam; Kecskes, Angela; Gaszner, Halazs; Filaretova, Ludmila Share Save Regulatory role of capsaicin-sensitive peptidergic sensory nerves in the proteoglycan-induced autoimmune arthritis model of the mouseHorvath, Adam; Borbely, Eva; Bolcskei, Kata; Szentes, Nikolett; Kiss, Tamas; Belak, Matyas; Rauch, Tibor; Glant, Tibor; Zakany, Roza; Juhasz, Tamas; Karanyicz, Edina; Boldizsar, Ferenc; Helyes, Zsuzsanna; Botz, Balint Share Save Share Save Analgesic effects of the novel semicarbazide-sensitive amine oxidase inhibitor SZV 1287 in mouse pain models with neuropathic mechanisms: Involvement of transient receptor potential vanilloid 1 and ankyrin 1 receptorsHorvath, Adam; Tekus, Valeria; Bencze, Noemi; Szentes, Nikolett; Scheich, Mint; Bolcskei, Kata; Szoke, Eva; Mocsai, Attila; Toth-Sarudy, Eva; Matyus, Peter; Pinter, Erika; Helyes, Zsuzsanna Share Save Share Save Analgesic and Anti-Inflammatory Effects of the Novel Semicarbazide-Sensitive Amine-Oxidase Inhibitor SzV-1287 in Chronic Arthritis Models of the MouseHorvath, Adam; Menghis, Awt; Botz, Balint; Borbely, Eva; Kemeny, Agnes; Tekus, Valeria; Csepregi, Janka Zsofia; Mocsai, Attila; Juhasz, Tamas; Zakany, Roza; Bogdan, Dora; Matyus, Peter; Keeble, Julie; Pinter, Erika; Helyes, Zsuzsanna Share Save Noxious heat threshold temperature and pronociceptive effects of allyl isothiocyanate (mustard oil) in TRPV1 or TRPA1 gene-deleted miceTekus, Valeria; Horvath, Adam; Hajna, Zsofia; Borbely, Eva; Bolcskei, Kata; Boros, Melinda; Pinter, Erika; Helyes, Zsuzsanna; Petho, Gabor; Szolcsanyi, Janos Share Save Share Save 
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