Not logged inLasso peptides sviceucin and siamycin I exhibit anti-virulence activity and restore vancomycin effectiveness in vancomycin-resistant pathogens
Boudrioua, Abdelhakim; Baetz, Benjamin; Desmadril, Solenn; Goulard, Christophe; Groo, Anne-Claire; Lombard, Carine; Gueulle, Sabrina; Marugan, Marie; Malzert-Freon, Aurelie; Hartke, Axel; Li, Yanyan; Giraud, Caroline
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SaveEvidence from a mouse model supports repurposing an anti-asthmatic drug, bambuterol, against Alzheimer's disease by administration through an intranasal route
Groo, Anne-Claire; Curel, Thomas; Malzert-Freon, Aurelie; Seguy, Line; Bento, Ophelie; Corvaisier, Sophie; Culerier, Thomas; Legrand, Romain; Callizot, Noelle; Henriques, Alexandre; Culley, Georgia; Claeysen, Sylvie; Rochais, Christophe; Dallemagne, Patrick
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SaveIn vitro evaluation of NA1-115-7-loaded nanoemulsions, an MCL-1-specific inhibitor of natural origin, intended to treat B-cell lymphoproliferative disorders after oral administration
Seguy, Line; Daressy, Florian; Lahlil, Sophia; Corvaisier, Sophie; Dumontet, Vincent; Litaudon, Marc; Apel, Cecile; Roussi, Fanny; Wiels, Joelle; Robert, Aude; Groo, Anne-Claire; Malzert-Freon, Aurelie
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SaveNA1-115-7, from Zygogynum pancheri, is a new selective MCL-1 inhibitor inducing the apoptosis of hematological cancer cells but non-toxic to normal blood cells or cardiomyocytes
Daressy, Florian; Seguy, Line; Favre, Loetitia; Corvaisier, Sophie; Apel, Cecile; Groo, Anne-Claire; Litaudon, Marc; Dumontet, Vincent; Malzert-Freon, Aurelie; Desrat, Sandy; Roussi, Fanny; Robert, Aude; Wiels, Joelle
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SaveActive Targeted Nanoemulsions for Repurposing of Tegaserod in Alzheimer's Disease Treatment
Seguy, Line; Guyon, Lena; Maurel, Manon; Verdie, Pascal; Davis, Audrey; Corvaisier, Sophie; Lisowski, Vincent; Dallemagne, Patrick; Groo, Anne-Claire; Malzert-Freon, Aurelie
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SaveDrimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL-1
Daressy, Florian; Malard, Florian; Seguy, Line; Guerineau, Vincent; Apel, Cecile; Dumontet, Vincent; Robert, Aude; Groo, Anne-Claire; Litaudon, Marc; Bignon, Jerome; Desrat, Sandy; Malzert-Freon, Aurelie; Wiels, Joelle; Lescop, Ewen; Roussi, Fanny
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SavePyridoclax-loaded nanoemulsion for enhanced anticancer effect on ovarian cancer
Groo, A. C.; Hedir, S.; Since, M.; Brotin, E.; Weiswald, L. -B.; Paysant, H.; Nee, G.; Coolzaet, M.; Goux, D.; Delepee, R.; Freret, T.; Poulain, L.; Voisin-Chiret, A. S.; Malzert-Freon, A.
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SavePharmacotechnical Development of a Nasal Drug Delivery Composite Nanosystem Intended for Alzheimer's Disease Treatment
Adnet, Thomas; Groo, Anne-Claire; Picard, Celine; Davis, Audrey; Corvaisier, Sophie; Since, Marc; Bounoure, Frederic; Rochais, Christophe; Le Pluart, Loic; Dallemagne, Patrick; Malzert-Freon, Aurelie
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SaveNF-κB-dependent DNA damage-signaling differentially regulates DNA double-strand break repair mechanisms in immature and mature human hematopoietic cells
Kraft, D.; Rall, M.; Volcic, M.; Metzler, E.; Groo, A.; Stahl, A.; Bauer, L.; Nasonova, E.; Salles, D.; Taucher-Scholz, G.; Boenig, H.; Fournier, C.; Wiesmueller, L.
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