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CGT 4.0: a distant dream or inevitable future? Smart process automation is critical to make efficient scalability of CGT manufacturing a reality Szarzynski, Aleksander; Spadiut, Oliver; Reisbeck, Matthias; Jobst, Gerhard; Paterson, Rachel L.; Kamenskaya, Anna; Gateau, Emilie; Lesch, Hanna P.; Henry, Luc; Kozma, Bence Share Save
Optimizing lentiviral vector formulation conditions for efficient ex vivo transduction of primary human T cells in chimeric antigen receptor T-cell manufacturing Luostarinen, Annu; Kailaanmaki, Anssi; Turkki, Vesa; Koylijarvi, Marjut; Kayhty, Piia; Leinonen, Hanna; Albers-Skirdenko, Vita; Lipponen, Eevi; Yla-Herttuala, Seppo; Kaartinen, Tanja; Lesch, Hanna P.; Kekarainen, Tuija Share Save
Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy (vol 9, 1052318, 2022) Eriksson, Reetta A. E.; Nieminen, Tiina; Galibert, Lionel; Peltola, Sanna K.; Tikkanen, Petra; Kayhty, Piia; Leinonen, Hanna M.; Oruetxebarria, Igor; Lepola, Saana; Valkama, Anniina J.; Lipponen, Eevi M.; Lesch, Hanna P.; Yla-Herttuala, Seppo; Airenne, Kari J. Share Save
Functional roles of the membrane-associated AAV protein MAAP Galibert, Lionel; Hyvonen, Amira; Eriksson, Reetta A. E.; Mattola, Salla; Aho, Vesa; Salminen, Sami; Albers, Justin D.; Peltola, Sanna K.; Weman, Saija; Nieminen, Tiina; Yla-Herttuala, Seppo; Lesch, Hanna P.; Vihinen-Ranta, Maija; Airenne, Kari J. Share Save
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Comparative Study of Adeno-associated Virus, Adenovirus, Bacu lovirus and Lentivirus Vectors for Gene Therapy of the Eyes Kalesnykas, Giedrius; Kokki, Emmi; Alasaarela, Laura; Lesch, Hanna P.; Tuulos, Timo; Kinnunen, Kati; Uusitalo, Hannu; Airenne, Kari; Yla-Herttuala, Seppo Share Save
Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages Eichenfield, Dawn Z.; Troutman, Ty Dale; Link, Verena M.; Lam, Michael T.; Cho, Han; Gosslin, David; Spann, Nathanael J.; Lesch, Hanna P.; Tao, Jenhan; Muto, Jun; Gallo, Richard L.; Evans, Ronald M.; Glass, Christopher K. Share Save
Consistent Viral Vector Manufacturing for Phase III Using iCELLis 500 Fixed-Bed Technology Karhinen, Minna; Nurminen, Elisa M.; Valonen, Piia; Rautsi, Outi; Huusko, Vesa; Heikkila, Kati; Weisell, Janne; Muller, Achim; Lesch, Hanna P.; Narvanen, Outi; Hassinen, Minna M.; Pollen, Minna; Parrish, Steve; Shaw, Robert; Parker, Nigel R.; Yla-Herttuala, Seppo Share Save
The Testing Strategy to Determine the Pharmacological Activity of Gene Therapy Drug Product (rAd-IFN) to Treat Intravesical Non-Muscle Invasive Bladder Cancer Hassinen, Minna M.; Mykkanen, Jenni; Lesch, Hanna; Paulo, Sara; Koponen, Taina; Lehtivarjo, Anna-Kaisa; Parrish, Steve; Shaw, Robert; Parker, Nigel R.; Yla-Herttuala, Seppo Share Save
Differential Promoter Methylation of Macrophage Genes Is Associated With Impaired Vascular Growth in Ischemic Muscles of Hyperlipidemic and Type 2 Diabetic Mice Genome-Wide Promoter Methylation Study Babu, Mohan; Devi, Thota Durga; Makinen, Petri; Kaikkonen, Minna; Lesch, Hanna P.; Junttila, Sini; Laiho, Asta; Ghimire, Bishwa; Gyenesei, Attila; Yla-Herttuala, Seppo Share Save
iCELLisTM Fixed-Bed Technology for Adherent Cells Is an Efficient Scalable System for Viral Vector Production Applications Lesch, Hanna P.; Valonen, Piia; Heikkila, Kati; Lipponen, Eevi; Muller, Achim; Rasanen, Eva; Tuunanen, Tarja; Malinen, Joonas; Martikainen, Anne; Salonen, Tuula; Nurminen, Elisa M.; Hassinen, Minna; Karhinen, Minna; Parker, Nigel; Shaw, Robert; Yla-Herttuala, Seppo Share Save
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Targeted delivery via avidin fusion protein: Intracellular fate of biotinylated doxorubicin derivative and cellular uptake kinetics and biodistribution of biotinylated liposomes Soininen, Suvi K.; Lehtolainen-Dalkilic, Pauliina; Karppinen, Tanja; Puustinen, Tiina; Dragneva, Galina; Kaikkonen, Minna U.; Jauhiainen, Marjo; Allart, Brigitte; Selwood, David L.; Wirth, Thomas; Lesch, Hanna P.; Maatta, Ann-Marie; Monkkonen, Jukka; Yla-Herttuala, Seppo; Ruponen, Marika Share Save
Oxidative Stress-Regulated Lentiviral TK/GCV Gene Therapy for Lung Cancer Treatment Leinonen, Hanna M.; Ruotsalainen, Anna-Kaisa; Maatta, Ann-Marie; Laitinen, Heidi M.; Kuosmanen, Suvi M.; Kansanen, Emilia; Pikkarainen, Jere T.; Lappalainen, Jari P.; Samaranayake, Haritha; Lesch, Hanna P.; Kaikkonen, Minna U.; Yla-Herttuala, Seppo; Levonen, Anna-Liisa Share Save
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Baculovirus-mediated vascular endothelial growth factor-DδNδC gene transfer induces angiogenesis in rabbit skeletal muscle Heikura, Tommi; Nieminen, Tiina; Roschier, Miia M.; Karvinen, Henna; Kaikkonen, Minna U.; Mahonen, Anssi J.; Lesch, Hanna P.; Rissanen, Tuomas T.; Laitinen, Olli H.; Airenne, Kari J.; Yla-Herttuala, Seppo Share Save
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