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H

Hiroshi Takeshima

kyoto university

75H-index
452Paper Count
2.2WCitation Count
Published Papers 157
Publication Date
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TRIC-A Loss Sensitizes the Heart to β-Adrenergic Stress and Drives Cardiomyocyte Death and Fibrosis
errBiomolecules
IF4.8
err2026-01-24
err0
errOAAI
errKi Ho Park; Daiju Yamazaki; Xinyu Zhou; Shinji Komazaki; Chengzhu Zhao; Miyuki Nishi; Jingsong Zhou; Hiroshi Takeshima; Jianjie Ma
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Knockout of the Intracellular Calcium Conducting Ion Channel Mitsugumin 23 (MG23) Protects Against Pressure Overload Induced Left Ventricular Hypertrophy and Cardiac Dysfunction
errthe faseb journal
IF0
err2026-01-22
err0
PREAI
errAmy M. Dorward; Gavin B. Robertson; Claire Sneddon; Richard C. Edel; Chloe L. O'Rourke; In Hwa Um; David J. Harrison; Miyuki Nishi; Hiroshi Takeshima; Colin E. Murdoch; Samantha J. Pitt
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errSave
TRIC-A Facilitates Sarcoplasmic Reticulum–Mitochondrial Ca2+ Signaling Crosstalk in Cardiomyocytes
errCells 2025, Vol. 14, Page 1579
IF0
err2025-10-11
err0
errOAAI
errAng Li; Xinyu Zhou; Ki Ho Park; Jianxun Yi; Xuejun Li; Jae-Kyun Ko; Yuchen Chen; Miyuki Nishi; Daiju Yamazaki; Hiroshi Takeshima; Jingsong Zhou; Jianjie Ma
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errSave
Macrophage migration inhibitory factor induces phospholamban phosphorylation in cardiac muscle
errCell Calcium
IF4
err2025-07-04
err0
errOAAI
errZihan Tang; Feng Liu; Miyuki Nishi; Fabienne Mackay; Mutsuo Harada; Hiroshi Takeshima
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errSave
MG53's non-physiologic interaction with insulin receptor: lack of effect on insulin-stimulated Akt phosphorylation in muscle, heart and liver tissues
errFRONTIERS IN ENDOCRINOLOGY
IF4.6
err2024-09-17
err0
errOAAI
errLee, Kyung Eun; Nishi, Miyuki; Kim, Jongsoo; Murayama, Takashi; Dawson, Zachary; Wang, Xiaoliang; Zhou, Xinyu; Tan, Tao; Cai, Chuanxi; Takeshima, Hiroshi; Park, Ki Ho
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errSave
Ca2+ storage function is altered in the sarcoplasmic reticulum of skeletal muscle lacking mitsugumin 23
errAMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
IF4.7
err2024-03-01
err1
PREAI
errWatanabe, Daiki; Nishi, Miyuki; Liu, Feng; Bian, Yuhan; Takeshima, Hiroshi
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errSave
Structure, Function, and Regulation of the Junctophilin Family
errANNUAL REVIEW OF PHYSIOLOGY
IF19.1
err2024-02-12
err2
PREAI
errHall, Duane D.; Takeshima, Hiroshi; Song, Long-Sheng
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errSave
Atypical cell death and insufficient matrix organization in long-bone growth plates from Tric-b-knockout mice
errCELL DEATH & DISEASE
IF9.6
err2023-12-20
err2
errOAAI
errIchimura, Atsuhiko; Miyazaki, Yuu; Nagatomo, Hiroki; Kawabe, Takaaki; Nakajima, Nobuhisa; Kim, Ga Eun; Tomizawa, Masato; Okamoto, Naoki; Komazaki, Shinji; Kakizawa, Sho; Nishi, Miyuki; Takeshima, Hiroshi
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The biophysical properties of TRIC-A and TRIC-B and their interactions with RyR2
errJOURNAL OF GENERAL PHYSIOLOGY
IF2.9
err2023-09-26
err0
errOAAI
errHu, Jianshu; Venturi, Elisa; Sigalas, Charalampos; Murayama, Takashi; Nishi, Miyuki; Takeshima, Hiroshi; Sitsapesan, Rebecca
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errSave
A Role of TMEM16E Carrying a Scrambling Domain in Sperm Motility
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-17
err65
errOAAI
errGyobu, Sayuri; Miyata, Haruhiko; Ikawa, Masahito; Yamazaki, Daiju; Takeshima, Hiroshi; Suzuki, Jun; Nagata, Shigekazu
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errSave
C-type natriuretic peptide facilitates autonomic Ca2+ entry in growth plate chondrocytes for stimulating bone growth
errELIFE
IF0
err2022-03-15
err15
errOAAI
errMiyazaki, Yuu; Ichimura, Atsuhiko; Kitayama, Ryo; Okamoto, Naoki; Yasue, Tomoki; Liu, Feng; Kawabe, Takaaki; Nagatomo, Hiroki; Ueda, Yohei; Yamauchi, Ichiro; Hakata, Takuro; Nakao, Kazumasa; Kakizawa, Sho; Nishi, Miyuki; Mori, Yasuo; Akiyama, Haruhiko; Nakao, Kazuwa; Takeshima, Hiroshi
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errSave
Biophysical characteristics of TRIC-A and TRIC-B channels and their regulation of RYR2: Calcium Signaling and Excitation-Contraction in Cardiac, Skeletal and Smooth Muscle
errJOURNAL OF GENERAL PHYSIOLOGY
IF2.9
err2021-11-12
err0
errOAAI
errHu, Jianshu; Venturi, Elisa; Sigalas, Charalampos; Murayama, Takashi; Nishi, Miyuki; Takeshima, Hiroshi; Sitsapesan, Rebecca
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errSave
BACE inhibitor treatment of mice induces hyperactivity in a Seizure-related gene 6 family dependent manner without altering learning and memory
errSCIENTIFIC REPORTS
IF3.9
err2021-07-23
err7
errOAAI
errNash, A.; Gijsen, H. J. M.; Hrupka, B. J.; Teng, K. S. -L.; Lichtenthaler, S. F.; Takeshima, H.; Gunnersen, J. M.; Munro, K. M.
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errSave
Enhanced Ca2+ handling in thioglycolate-elicited peritoneal macrophages
errCELL CALCIUM
IF4
err2021-06-01
err4
PREAI
errLiu, Feng; Xu, Luxin; Nishi, Miyuki; Ichimura, Atsuhiko; Takeshima, Hiroshi
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errSave
Rieske iron-sulfur protein induces FKBP12.6/RyR2 complex remodeling and subsequent pulmonary hypertension through NF-κB/cyclin D1 pathway
errNATURE COMMUNICATIONS
IF15.7
err2020-07-15
err27
errOAAI
errMei, Lin; Zheng, Yun-Min; Song, Tengyao; Yadav, Vishal R.; Joseph, Leroy C.; Truong, Lillian; Kandhi, Sharath; Barroso, Margarida M.; Takeshima, Hiroshi; Judson, Marc A.; Wang, Yong-Xiao
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errSave
TRIC-A Channel Maintains Store Calcium Handling by Interacting With Type 2 Ryanodine Receptor in Cardiac Muscle
errCIRCULATION RESEARCH
IF16.2
err2020-02-14
err21
errOAAI
errZhou Xinyu; Park, Ki Ho; Yamazaki, Daiju; Lin Pei-hui; Nishi, Miyuki; Ma Zhiwei; Qiu Liming; Murayama, Takashi; Zou Xiaoqin; Takeshima, Hiroshi; Zhou Jingsong; Ma Jianjie
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errSave
A junctophilin-caveolin interaction enables efficient coupling between ryanodine receptors and BKCa channels in the Ca2+ microdomain of vascular smooth muscle
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2019-08-01
err31
errOAAI
errSaeki, Takanori; Suzuki, Yoshiaki; Yamamura, Hisao; Takeshima, Hiroshi; Imaizumi, Yuji
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errSave
Calcium phosphate mineralization in bone tissues directly observed in aqueous liquid by atmospheric SEM (ASEM) without staining: microfluidics crystallization chamber and immuno-EM
errSCIENTIFIC REPORTS
IF3.9
err2019-05-14
err16
errOAAI
errSato, Chikara; Yamazaki, Daiju; Sato, Mari; Takeshima, Hiroshi; Memtily, Nassirhadjy; Hatano, Yuri; Tsukuba, Takayuki; Sakai, Eiko
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errSave
Extraocular muscle function is impaired in ryr3-/- mice
errJOURNAL OF GENERAL PHYSIOLOGY
IF2.9
err2019-05-13
err14
errOAAI
errEckhardt, Jan; Bachmann, Christoph; Sekukc-Jablanovic, Marijana; Enzmann, Volker; Park, Ki Ho; Ma, Jianjie; Takeshima, Hiroshi; Zorzato, Francesco; Treves, Susan
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errSave
TRPM7 channels mediate spontaneous Ca2+ fluctuations in growth plate chondrocytes that promote bone development
errSCIENCE SIGNALING
IF6.6
err2019-04-09
err22
PREAI
errQian, Nianchao; Ichimura, Atsuhiko; Takei, Daisuke; Sakaguchi, Reiko; Kitani, Akihiro; Nagaoka, Ryohei; Tomizawa, Masato; Miyazaki, Yuu; Miyachi, Hitoshi; Numata, Tomohiro; Kakizawa, Sho; Nishi, Miyuki; Mori, Yasuo; Takeshima, Hiroshi
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Research Directions

No research directions
Co-authors
Cooperation Journals
S
Shizuo Akira
H-index: 269 · Papers: 1.5K
K
Kenji Kangawa
H-index: 144 · Papers: 1.3K
B
Bart De Strooper
H-index: 142 · Papers: 684
K
Kiyoshi Takeda
H-index: 135 · Papers: 669
S
Shigekazu Nagata
H-index: 133 · Papers: 865
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