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SaveShare Save Share Save Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis
Lafaille, Fabien G.; Harschnitz, Oliver; Lee, Yoon Seung; Zhang, Peng; Hasek, Mary L.; Kerner, Gaspard; Itan, Yuval; Ewaleifoh, Osefame; Rapaport, Franck; Carlile, Thomas M.; Carter-Timofte, Madalina E.; Paquet, Dominik; Dobbs, Kerry; Zimmer, Bastian; Gao, Daxing; Rojas-Duran, Maria F.; Kwart, Dylan; Rattina, Vimel; Ciancanelli, Michael J.; McAlpine, Jessica L.; Lorenzo, Lazaro; Boucherit, Soraya; Rozenberg, Flore; Halwani, Rabih; Henry, Benoit; Amenzoui, Naima; Alsum, Zobaida; Marques, Laura; Church, Joseph A.; Al-Muhsen, Saleh; Tardieu, Marc; Bousfiha, Ahmed Aziz; Paludan, Soren R.; Mogensen, Trine Hyrup; Quintana-Murci, Lluis; Tessier-Lavigne, Marc; Smith, Gregory A.; Notarangelo, Luigi D.; Studer, Lorenz; Gilbert, Wendy; Abel, Laurent; Casanova, Jean-Laurent; Zhang, Shen-Ying Share Save Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCsCornacchia, Daniela; Zhang, Chao; Zimmer, Bastian; Chung, Sun Young; Fan, Yujie; Soliman, Mohamed A.; Tchieu, Jason; Chambers, Stuart M.; Shah, Hardik; Paull, Daniel; Konrad, Csaba; Vincendeau, Michelle; Noggle, Scott A.; Manfredi, Giovanni; Finley, Lydia W. S.; Cross, Justin R.; Betel, Doron; Studer, Lorenz Share Save HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neuronsKishinevsky, Sarah; Wang, Tai; Rodina, Anna; Chung, Sun Young; Xu, Chao; Philip, John; Taldone, Tony; Joshi, Suhasini; Alpaugh, Mary L.; Bolaender, Alexander; Gutbier, Simon; Sandhu, Davinder; Fattahi, Faranak; Zimmer, Bastian; Shah, Smit K.; Chang, Elizabeth; Inda, Carmen; Koren, John, III; Saurat, Nathalie G.; Leist, Marcel; Gross, Steven S.; Seshan, Venkatraman E.; Klein, Christine; Tomishima, Mark J.; Erdjument-Bromage, Hediye; Neubert, Thomas A.; Henrickson, Ronald C.; Chiosis, Gabriela; Studer, Lorenz Share Save Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infectionZimmer, Bastian; Ewaleifoh, Osefame; Harschnitz, Oliver; Lee, Yoon-Seung; Peneau, Camille; McAlpine, Jessica L.; Liu, Becky; Tchieu, Jason; Steinbeck, Julius A.; Lafaille, Fabien; Volpi, Stefano; Notarangelo, Luigi D.; Casanova, Jean-Laurent; Zhang, Shen-Ying; Smith, Gregory A.; Studer, Lorenz Share Save Share Save Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cellsQi, Yuchen; Zhang, Xin-Jun; Renier, Nicolas; Wu, Zhuhao; Atkin, Talia; Sun, Ziyi; Ozair, M. Zeeshan; Tchieu, Jason; Zimmer, Bastian; Fattahi, Faranak; Ganat, Yosif; Azevedo, Ricardo; Zeltner, Nadja; Briyanlou, Ali H.; Karayiorgou, Maria; Gogos, Joseph; Tomishima, Mark; Tessier-Lavigne, Marc; Shi, Song-Hai; Studer, Lorenz Share Save Capturing the biology of disease severity in a PSC-based model of familial dysautonomiaZeltner, Nadja; Fattahi, Faranak; Dubois, Nicole C.; Saurat, Nathalie; Lafaille, Fabien; Shang, Lei; Zimmer, Bastian; Tchieu, Jason; Soliman, Mohamed A.; Lee, Gabsang; Casanova, Jean-Laurent; Studer, Lorenz Share Save Share Save Reference Compounds for Alternative Test Methods to Indicate Developmental Neurotoxicity (DNT) Potential of Chemicals: Example Lists and Criteria for their Selection and UseAschner, Michael; Ceccatelli, Sandra; Daneshian, Mardas; Fritsche, Ellen; Hasiwa, Nina; Hartung, Thomas; Hogberg, Helena T.; Leist, Marcel; Li, Abby; Mundy, William R.; Padilla, Stephanie; Piersma, Aldert H.; Bal-Price, Anna; Seiler, Andrea; Westerink, Remco H.; Zimmer, Bastian; Lein, Pamela J. Share Save Grouping of histone deacetylase inhibitors and other toxicants disturbing neural crest migration by transcriptional profilingDreser, Nadine; Zimmer, Bastian; Dietz, Christian; Suegis, Elena; Pallocca, Giorgia; Nyffeler, Johanna; Meisig, Johannes; Bluethgen, Nils; Berthold, Michael R.; Waldmann, Tanja; Leist, Marcel Share Save Share Save Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test batteryZimmer, B.; Pallocca, G.; Dreser, N.; Foerster, S.; Waldmann, T.; Westerhout, J.; Julien, S.; Krause, K. H.; van Thriel, C.; Hengstler, J. G.; Sachinidis, A.; Bosgra, S.; Leist, M. Share Save Share Save Share Save Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndromeBalmer, Nina V.; Weng, Matthias K.; Zimmer, Bastian; Ivanova, Violeta N.; Chambers, Stuart M.; Nikolaeva, Elena; Jagtap, Smita; Sachinidis, Agapios; Hescheler, Juergen; Waldmann, Tanja; Leist, Marcel Share Save Share Save Share Save 
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