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Adoptive transfer of personalized neoantigen-reactive TCR-transduced T cells in metastatic colorectal cancer: phase 2 trial interim results Parkhurst, Maria; Goff, Stephanie L.; Lowery, Frank J.; Beyer, Rachel K.; Halas, Hyunmi; Robbins, Paul F.; Prickett, Todd D.; Gartner, Jared J.; Sindiri, Sivasish; Krishna, Sri; Zacharakis, Nikolaos; Ngo, Lien; Ray, Satyajit; Bera, Alakesh; Shepherd, Ryan; Levin, Noam; Kim, Sanghyun P.; Copeland, Amy; Nah, Shirley; Levi, Shoshana; Parikh, Neilesh; Kwong, Mei Li M.; Klemen, Nicholas D.; Yang, James C.; Rosenberg, Steven A. Share Save
Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes Levin, Noam; Kim, Sanghyun P.; Marquardt, Charles A.; Vale, Nolan R.; Yu, Zhiya; Sindiri, Sivasish; Gartner, Jared J.; Parkhurst, Maria; Krishna, Sri; Lowery, Frank J.; Zacharakis, Nikolaos; Levy, Lior; Prickett, Todd D.; Benzine, Tiffany; Ray, Satyajit; Masi, Robert, V; Gasmi, Billel; Li, Yong; Islam, Rafiqul; Bera, Alakesh; Goff, Stephanie L.; Robbins, Paul F.; Rosenberg, Steven A. Share Save
IMPACT restrains immuno-metabolic GCN1 signaling to govern pancreatic cancer metastasis Sinha, Surajit; Panda, Abir; Nwosu, Zeribe; Das, Rodrigo Neves; Ke, Xu; van Beek, Elke; Rossi, Alexander J.; Ayabe, Reed I.; McDonald, James; Wach, Michael M.; Ruff, Samantha; Desai, Priyanka P.; Sun, David; Teke, Martha E.; Verbus, Emily A.; Saif, Areeba; Gupta, Shreya; Khan, Tahsin; Sarvestani, Leila; Ryan, Carrie E.; Lambdin, Jacob; Remmert, Kirsten; Smith, Emily; Luberice, Kenneth; Lux, Stephie; Alexander, Imani A.; Pu, Tracey; Luna, Allen; Akmal, Sarfraz R.; Rehman, Shahyan; Rainey, Ashley; Hong, Hanna; Lin, Yuri; Sevilla, Samantha; Billel, Gasmi; Sindiri, Sivasish; Prickett, Todd; Chan, King; Li, Eileen; Wu, Xiaolin; Klemen, Nicholas D.; Trinchieri, Giorgio; Lyssiotis, Costas A.; Davis, Jeremy; Singh, Pankaj K.; Rosenberg, Steven A.; Yaffe, Michael B.; Giancotti, Filippo; Shevach, Ethan M.; Hernandez, Jonathan M. Share Save
Replication competent retrovirus testing (RCR) in the National Gene Vector Biorepository: No evidence of RCR in 1,595 post-treatment peripheral blood samples obtained from 60 clinical trials Cornetta, Kenneth; Yao, Jing; House, Kimberley; Duffy, Lisa; Adusumilli, Prasad S.; Beyer, Rachel; Booth, Claire; Brenner, Malcolm; Curran, Kevin; Grilley, Bambi; Heslop, Helen; Hinrichs, Christian S.; Kaplan, Rosandra N.; Kiem, Hans-Peter; Kochenderfer, James; Kohn, Donald B.; Mailankody, Sham; Norberg, Scott M.; O'Cearbhaill, Roisin E.; Pappas, Jennifer; Park, Jae; Ramos, Carlos; Ribas, Antonio; Riviere, Isabelle; Rosenberg, Steven A.; Sauter, Craig; Shah, Nirali N.; Slovin, Susan F.; Thrasher, Adrian; Williams, David A.; Lin, Tsai-Yu Share Save
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Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade Palmer, Douglas C.; Webber, Beau R.; Patel, Yogin; Johnson, Matthew J.; Kariya, Christine M.; Lahr, Walker S.; Parkhurst, Maria R.; Gartner, Jared J.; Prickett, Todd D.; Lowery, Frank J.; Kishton, Rigel J.; Gurusamy, Devikala; Franco, Zulmarie; Vodnala, Suman K.; Diers, Miechaleen D.; Wolf, Natalie K.; Slipek, Nicholas J.; McKenna, David H.; Sumstad, Darin; Viney, Lydia; Henley, Tom; Burckstummer, Tilmann; Baker, Oliver; Hu, Ying; Yan, Chunhua; Meerzaman, Daoud; Padhan, Kartik; Lo, Winnie; Malekzadeh, Parisa; Jia, Li; Deniger, Drew C.; Patel, Shashank J.; Robbins, Paul F.; McIvor, R. Scott; Choudhry, Modassir; Rosenberg, Steven A.; Moriarity, Branden S.; Restifo, Nicholas P. Share Save
Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer Leidner, Rom; Silva, Nelson Sanjuan; Huang, Huayu; Sprott, David; Zheng, Chunhong; Shih, Yi-Ping; Leung, Amy; Payne, Roxanne; Sutcliffe, Kim; Cramer, Julie; Rosenberg, Steven A.; Fox, Bernard A.; Urba, WalterJ; Tran, Eric Share Save
MOLECULAR SIGNATURE OF NEOANTIGEN-REACTIVE CD4+AND CD8+T CELLS FROM METASTATIC HUMAN CANCERS ENABLES PROSPECTIVE ANTITUMOR TCR PREDICTION Lowery, Frank; Krishna, Sri; Yoseph, Rami; Parikh, Neilesh; Chatani, Praveen; Lu, Yong-Chen William; Zacharakis, Nikolaos; Robbins, Paul; Parkhurst, Maria; Rosenberg, Steven Share Save
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Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma Peri, Aviyah; Greenstein, Erez; Alon, Michal; Pai, Joy A.; Dingjan, Tamir; Reich-Zeliger, Shlomit; Barnea, Eilon; Barbolin, Chaya; Levy, Ronen; Arnedo-Pac, Claudia; Kalaora, Shelly; Dassa, Bareket; Feldmesser, Ester; Shang, Ping; Greenberg, Polina; Levin, Yishai; Benedek, Gil; Levesque, Mitchell P.; Adams, David J.; Lotem, Michal; Wilmott, James S.; Scolyer, Richard A.; Joensson, Goeran B.; Admon, Arie; Rosenberg, Steven A.; Cohen, Cyrille J.; Niv, Masha Y.; Lopez-Bigas, Nuria; Satpathy, Ansuman T.; Friedman, Nir; Samuels, Yardena Share Save
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A machine learning model for ranking candidate HLA class I neoantigens based on known neoepitopes from multiple human tumor types Gartner, Jared J.; Parkhurst, Maria R.; Gros, Alena; Tran, Eric; Jafferji, Mohammad S.; Copeland, Amy; Hanada, Ken-Ichi; Zacharakis, Nikolaos; Lalani, Almin; Krishna, Sri; Sachs, Abraham; Prickett, Todd D.; Li, Yong F.; Florentin, Maria; Kivitz, Scott; Chatmon, Samuel C.; Rosenberg, Steven A.; Robbins, Paul F. Share Save
Rapid Identification and Evaluation of Neoantigen-reactive T-Cell Receptors From Single Cells Paria, Biman C.; Levin, Noam; Lowery, Frank J.; Pasetto, Anna; Deniger, Drew C.; Parkhurst, Maria R.; Yossef, Rami; Kim, Sanghyun P.; Florentin, Maria; Ngo, Lien T.; Ray, Satyajit; Krishna, Sri; Robbins, Paul F.; Rosenberg, Steven A. Share Save
mRNA vaccine-induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer Cafri, Gal; Gartner, Jared J.; Zaks, Tal; Hopson, Kristen; Levin, Noam; Paria, Biman C.; Parkhurst, Maria R.; Yossef, Rami; Lowery, Frank J.; Jafferji, Mohammad S.; Prickett, Todd D.; Goff, Stephanie L.; McGowan, Christine T.; Seitter, Samantha; Shindorf, Mackenzie L.; Parikh, Anup; Chatani, Praveen D.; Robbins, Paul F.; Rosenberg, Steven A. Share Save
Tumor infiltrating lymphocytes (TIL) recognize a unique and diverse number of non-synonymous somatic mutations in patients with metastatic breast cancer Zacharakis, Nikolaos; Kim, Peter; Robbins, Paul; Gartner, Jared; Prickett, Todd; Hill, Victoria; Paria, Biman; Feldman, Steven; Goff, Stephanie; Rosenberg, Steven Share Save
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