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Efficacy and safety of bosutinib in previously treated patients with chronic myeloid leukemia: final results from the BYOND trial Gambacorti-Passerini, Carlo; Bruemmendorf, Tim H.; Abruzzese, Elisabetta; Kelly, Kevin R.; Oehler, Vivian G.; Garcia-Gutierrez, Valentin; Hjorth-Hansen, Henrik; Ernst, Thomas; Leip, Eric; Purcell, Simon; Luscan, Gerald; Viqueira, Andrea; Giles, Francis J.; Hochhaus, Andreas Share Save
Impact of age and comorbidities on the efficacy and tolerability of bosutinib in previously treated patients with chronic myeloid leukemia: results from the phase 4 BYOND study Rosti, Gianantonio; Bruemmendorf, Tim H.; Gjertsen, Bjoern T.; Giraldo-Castellano, Pilar; Castagnetti, Fausto; Gambacorti-Passerini, Carlo; Ernst, Thomas; Zhao, Huadong; Kuttschreuter, Luke; Purcell, Simon; Giles, Francis J.; Hochhaus, Andreas Share Save
Dual inhibition of BET and HAT/p300 suppresses colorectal cancer via DR5-and p53/PUMA-mediated cell death Kuang, Chaoyuan; Tong, Jingshan; Ermine, Kaylee; Cai, Manbo; Dai, Fujun; Hao, Suisui; Giles, Francis; Huang, Yi; Yu, Jian; Zhang, Lin Share Save
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Clinical activity of 9-ING-41, a small molecule selective glycogen synthase kinase-3 beta (GSK-3β) inhibitor, in refractory adult T-Cell leukemia/lymphoma Hsu, Andrew; Huntington, Kelsey E.; De Souza, Andre; Zhou, Lanlan; Olszewski, Adam J.; Makwana, Nirav P.; Treaba, Diana O.; Cavalcante, Ludimila; Giles, Francis J.; Safran, Howard; El-Deiry, Wafik S.; Carneiro, Benedito A. Share Save
Malignant glioma subset from actuate 1801: Phase I/II study of 9-ING-41, GSK-3β inhibitor, monotherapy or combined with chemotherapy for refractory malignancies Odia, Yazmin; Cavalcante, Ludimila; Safran, Howard; Powell, Steven Francis; Munster, Pamela N.; Ma, Wen Wee; Carneiro, Benedito A.; Bastos, Bruno R.; Mikrut, Stacy; Mikrut, William; Giles, Francis J.; Sahebjam, Solmaz Share Save
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Genomic biomarkers for response to 9-ING-41, a small molecule selective glycogen synthase kinase-3 (GSK-3) inhibitor, in pancreas cancer: Preliminary results Borden, Brittany A.; De Souza, Andre; Mahalingam, Devalingam; Powell, Steven; Munster, Pamela N.; Huntington, Kelsey; Mazar, Andrew; Calvacante, Ludmila; Giles, Francis J.; El-Deiry, Wafik S.; Safran, Howard P.; Carneiro, Benedito A. Share Save
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Treatment-free remission following frontline nilotinib in patients with chronic phase chronic myeloid leukemia: 5-year update of the ENESTfreedom trial Radich, Jerald P.; Hochhaus, Andreas; Masszi, Tamas; Hellmann, Andrzej; Stentoft, Jesper; Casares, Maria Teresa Gomez; Garcia-Gutierrez, J. Valentin; Conneally, Eibhlin; le Coutre, Philipp D.; Gattermann, Norbert; Martino, Bruno; Saussele, Susanne; Giles, Francis J.; Ross, David M.; Aimone, Paola; Li, Sai; Titorenko, Ksenia; Saglio, Giuseppe Share Save
A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma Kumthekar, Priya; Ko, Caroline H.; Paunesku, Tatjana; Dixit, Karan; Sonabend, Adam M.; Bloch, Orin; Tate, Matthew; Schwartz, Margaret; Zuckerman, Laura; Lezon, Ray; Lukas, Rimas, V; Jovanovic, Borko; McCortney, Kathleen; Colman, Howard; Chen, Si; Lai, Barry; Antipova, Olga; Deng, Junjing; Li, Luxi; Tommasini-Ghelfi, Serena; Hurley, Lisa A.; Unruh, Dusten; Sharma, Nitya, V; Kandpal, Manoj; Kouri, Fotini M.; Davuluri, Ramana, V; Brat, Daniel J.; Muzzio, Miguel; Glass, Mitchell; Vijayakumar, Vinod; Heidel, Jeremy; Giles, Francis J.; Adams, Ann K.; James, C. David; Woloschak, Gayle E.; Horbinski, Craig; Stegh, Alexander H. Share Save
Bromodomain and extra-terminal inhibitors-A consensus prioritisation after the Paediatric Strategy Forum for medicinal product development of epigenetic modifiers in children-ACCELERATE Pearson, Andrew D. J.; DuBois, Steven G.; Buenger, Vickie; Kieran, Mark; Stegmaier, Kimberly; Bandopadhayay, Pratiti; Bennett, Kelly; Bourdeaut, Franck; Brown, Patrick A.; Chesler, Louis; Clymer, Jessica; Fox, Elizabeth; French, Christopher A.; Germovsek, Eva; Giles, Francis J.; Bender, Julia G.; Hattersley, Maureen M.; Ludwinski, Donna; Luptakova, Katarina; Maris, John; McDonough, Joe; Nikolova, Zariana; Smith, Malcolm; Tsiatis, Athanasios C.; Vibhakar, Rajeev; Weiner, Susan; Yi, Joanna S.; Zheng, Fred; Vassal, Gilles Share Save
Moxetumomab pasudotox in heavily pre-treated patients with relapsed/refractory hairy cell leukemia (HCL): long-term follow-up from the pivotal trial Kreitman, Robert J.; Dearden, Claire; Zinzani, Pier Luigi; Delgado, Julio; Robak, Tadeusz; le Coutre, Philipp D.; Gjertsen, Bjorn T.; Troussard, Xavier; Roboz, Gail J.; Karlin, Lionel; Gladstone, Douglas E.; Kuptsova-Clarkson, Nataliya; Liu, Shiyao; Patel, Priti; Rotolo, Federico; Mitry, Emmanuel; Pastan, Ira; Giles, Francis Share Save
The Landscape of Glycogen Synthase Kinase-3 Beta Genomic Alterations in Cancer Borden, Brittany A.; Baca, Yasmine; Xiu, Joanne; Tavora, Fabio; Winer, Ira; Weinberg, Benjamin A.; Vanderwalde, Ari M.; Darabi, Sourat; Korn, W. Michael; Mazar, Andrew P.; Giles, Francis J.; Crawford, Lorin; Safran, Howard; El-Deiry, Wafik S.; Carneiro, Benedito A. Share Save
Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734 Spriano, Filippo; Gaudio, Eugenio; Cascione, Luciano; Tarantelli, Chiara; Melle, Federica; Motta, Giovanna; Priebe, Valdemar; Rinaldi, Andrea; Golino, Gaetanina; Mensah, Afua Adjeiwaa; Aresu, Luca; Zucca, Emanuele; Pileri, Stefano; Witcher, Michael; Brown, Bill; Wahlestedt, Claes; Giles, Francis; Stathis, Anastasios; Bertoni, Francesco Share Save
Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer Vatapalli, R.; Sagar, V.; Rodriguez, Y.; Zhao, J. C.; Unno, K.; Pamarthy, S.; Lysy, B.; Anker, J.; Han, H.; Yoo, Y. A.; Truica, M.; Chalmers, Z. R.; Giles, F.; Yu, J.; Chakravarti, D.; Carneiro, B.; Abdulkadir, S. A. Share Save
Glycogen synthase kinase-3 beta (GSK-3b) genomic alterations and increased programmed death-ligand 1 (PD-L1) expression in advanced malignancies Borden, Brittany A.; Xiu, Joanne; Baca, Yasmine; Ramos, Pilar; Giles, Francis J.; Mazar, Andrew; Tavora, Fabio; Safran, Howard; El-Deiry, Wafik S.; Carneiro, Benedito A. Share Save
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