Eric C. Lai - Publications, H-index & Citations

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Eric C. Lai

sloan kettering institute

84H-index

290Paper Count

3.2WCitation Count

Published Papers 142

Publication Date

Human DICER1 hotspot mutation induces both loss and gain of miRNA function

Nature Structural & Molecular Biology

IF10.1

2025-11-04

PREAI

David Jee; Seungjae Lee; Dapeng Yang; Robert Rickert; Renfu Shang; Danwei Huangfu; Eric C. Lai

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Repeated emergence of giant microRNA hairpins across invertebrates

Cell Reports

IF6.9

2025-09-10

OAAI

Mir-Mammad Javad-zada; Xiaodong Zou; Katsutomo Okamura; Renfu Shang; Ankur Garg; Ethan Lee; Leemor Joshua-Tor; Bastian Fromm; Eric C. Lai

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Mapping the microRNA landscape in the older adult brain and its genetic contribution to neuropsychiatric conditions

NATURE AGING

IF19.4

2024-12-06

OAAI

Vattathil, Selina M.; Gerasimov, Ekaterina S.; Canon, Se Min; Lori, Adriana; Tan, Sarah Sze Min; Kim, Paul J.; Liu, Yue; Lai, Eric C.; Bennett, David A.; Wingo, Thomas S.; Wingo, Aliza P.

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The structural landscape of Microprocessor-mediated processing of pri-let-7 miRNAs

MOLECULAR CELL

IF16.6

2024-11-01

OAAI

Garg, Ankur; Shang, Renfu; Cvetanovic, Todor; Lai, Eric C.; Joshua-Tor, Leemor

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PIWI-interacting RNAs: who, what, when, where, why, and how

EMBO JOURNAL

IF8.3

2024-09-26

OAAI

Haase, Astrid D.; Ketting, Rene F.; Lai, Eric C.; van Rij, Ronald P.; Siomi, Mikiko; Svoboda, Petr; van Wolfswinkel, Josien C.; Wu, Pei-Hsuan

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The rapidly evolving X-linked MIR-506 family fine-tunes spermatogenesis to enhance sperm competition

ELIFE

IF0

2024-04-19

OAAI

Wang, Zhuqing; Wang, Yue; Zhou, Tong; Chen, Sheng; Morris, Dayton; Magalhaes, Rubens Daniel Miserani; Li, Musheng; Wang, Shawn; Wang, Hetan; Xie, Yeming; McSwiggin, Hayden; Oliver, Daniel; Yuan, Shuiqiao; Zheng, Huili; Mohammed, Jaaved; Lai, Eric C.; McCarrey, John R.; Yan, Wei

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A tailed mirtron promotes longevity in Drosophila

NUCLEIC ACIDS RESEARCH

IF13.1

2023-12-04

OAAI

Khanal, Sweta; de Cruz, Matthew; Strickland, Britton; Mansfield, Kody; Lai, Eric C.; Flynt, Alex

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Regulation of alternative splicing and polyadenylation in neurons

LIFE SCIENCE ALLIANCE

IF2.9

2023-10-04

OAAI

Lee, Seungjae; Aubee, Joseph, I; Lai, Eric C.

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Parameters of clustered suboptimal miRNA biogenesis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-10-03

OAAI

Shang, Renfu; Lai, Eric C.

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Proliferation and dissemination of killer meiotic drive loci

CURRENT OPINION IN GENETICS & DEVELOPMENT

IF3.6

2023-10-01

OAAI

Lai, Eric C.; Vogan, Aaron A.

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Rapid evolutionary diversification of the flamenco locus across simulans clade Drosophila species

PLOS GENETICS

IF3.7

2023-08-29

OAAI

Signor, Sarah; Vedanayagam, Jeffrey; Kim, Bernard Y.; Wierzbicki, Filip; Kofler, Robert; Lai, Eric C.

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Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision

NATURE METHODS

IF32.1

2023-07-13

OAAI

Vromman, Marieke; Anckaert, Jasper; Bortoluzzi, Stefania; Buratin, Alessia; Chen, Chia-Ying; Chu, Qinjie; Chuang, Trees-Juen; Dehghannasiri, Roozbeh; Dieterich, Christoph; Dong, Xin; Flicek, Paul; Gaffo, Enrico; Gu, Wanjun; He, Chunjiang; Hoffmann, Steve; Izuogu, Osagie; Jackson, Michael S.; Jakobi, Tobias; Lai, Eric C.; Nuytens, Justine; Salzman, Julia; Santibanez-Koref, Mauro; Stadler, Peter; Thas, Olivier; Eynde, Eveline Vanden; Verniers, Kimberly; Wen, Guoxia; Westholm, Jakub; Yang, Li; Ye, Chu-Yu; Yigit, Nurten; Yuan, Guo-Hua; Zhang, Jinyang; Zhao, Fangqing; Vandesompele, Jo; Volders, Pieter-Jan

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microRNAs in action: biogenesis, function and regulation

NATURE REVIEWS GENETICS

IF52

2023-06-28

194

PREAI

Shang, Renfu; Lee, Seungjae; Senavirathne, Gayan; Lai, Eric C.

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Regulatory logic of endogenous RNAi in silencing de novo genomic conflicts

PLOS GENETICS

IF3.7

2023-06-21

OAAI

Vedanayagam, Jeffrey C.; Lin, Ching-Jung; Papareddy, Ranjith; Nodine, Michael; Flynt, Alex; Wen, Jiayu; Lai, Eric

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Unanticipated broad phylogeny of BEN DNA-binding domains revealed by structural homology searches

CURRENT BIOLOGY

IF7.5

2023-06-01

OAAI

Pan, Anyu; Zeng, Yangfan; Liu, Jingjing; Zhou, Mengjie; Lai, Eric C.; Yu, Yang

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A Drosophila pasha Mutant Distinguishes the Canonical MicroRNA and Mirtron Pathways

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

OAAI

Martin, Raquel; Smibert, Peter; Yalcin, Abdullah; Tyler, David M.; Schaefer, Ulrich; Tuschl, Thomas; Lai, Eric C.

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R2D2 Organizes Small Regulatory RNA Pathways in Drosophila

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Okamura, Katsutomo; Robine, Nicolas; Liu, Ying; Liu, Qinghua; Lai, Eric C.

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Promiscuous splicing-derived hairpins are dominant substrates of tailing-mediated defense of miRNA biogenesis in mammals

CELL REPORTS

IF6.9

2023-02-01

OAAI

Lee, Seungjae; Jee, David; Srivatsava, Sid; Yang, Acong; Ramidi, Abhinav; Shang, Renfu; Bortoamiol-Becet, Diane; Pfeffer, Sebastien; Gu, Shuo; Wen, Jiayu; Lai, Eric C.

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Diverse cell-specific patterns of alternative polyadenylation in Drosophila

NATURE COMMUNICATIONS

IF15.7

2022-09-13

OAAI

Lee, Seungjae; Chen, Yen-Chung; Gillen, Austin E.; Taliaferro, J. Matthew; Deplancke, Bart; Li, Hongjie; Lai, Eric C.

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Regulated dicing of pre-mir-144 via reshaping of its terminal loop

NUCLEIC ACIDS RESEARCH

IF13.1

2022-07-08

OAAI

Shang, Renfu; Kretov, Dmitry A.; Adamson, Scott, I; Treiber, Thomas; Treiber, Nora; Vedanayagam, Jeffrey; Chuang, Jeffrey H.; Meister, Gunter; Cifuentes, Daniel; Lai, Eric C.

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Research Directions