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Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated With Age-Related Corneal Dystrophies Briere, Andrew; Vo, Peter; Yang, Benjamin; Adams, David; Amano, Takanori; Amarie, Oana; Berberovic, Zorana; Bower, Lynette; Brown, Steve D. M.; Burrill, Samantha; Cho, Soo Young; Clementson-Mobbs, Sharon; D'souza, Abigail; Eskandarian, Mohammad; Flenniken, Ann M.; Fuchs, Helmut; Gailus-Durner, Valerie; Herault, Yann; de Angelis, Martin Hrabe; Jin, Shundan; Joynson, Russell; Kang, Yeon Kyung; Kim, Haerim; Masuya, Hiroshi; Meziane, Hamid; Nam, Ki-Hoan; Noh, Hyuna; Nutter, Lauryl M. J.; Palkova, Marcela; Prochazka, Jan; Raishbrook, Miles Joseph; Riet, Fabrice; Salazar, Jason; Sedlacek, Radislav; Selloum, Mohammed; Seo, Kyoung Yul; Seong, Je Kyung; Shin, Hae-Sol; Shiroishi, Toshihiko; Stewart, Michelle; Svenson, Karen; Tamura, Masaru; Tolentino, Heather; Wells, Sara; Wurst, Wolfgang; Yoshiki, Atsushi; Lanoue, Louise; Lloyd, K. C. Kent; Leonard, Brian C.; Roux, Michel J.; McKerlie, Colin; Moshiri, Ala Share Save
Establishment and behavioural characterization of a novel constitutive P2X7 receptor knockout mouse line von Muecke-Heim, Iven-Alex; Oldekamp, Judit; Metzger, Michael W.; Klaffgen, Sarah; Tang, Hao; Walser, Sandra M.; Dedic, Nina; Rammes, Gerhard; Holsboer, Florian; Wurst, Wolfgang; Deussing, Jan M. Share Save
Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes Vo, Peter; Imai-Leonard, Denise M.; Yang, Benjamin; Briere, Andrew; Shao, Andy; Casanova, M. Isabel; Adams, David; Amano, Takanori; Amarie, Oana; Berberovic, Zorana; Bower, Lynette; Braun, Robert; Brown, Steve; Burrill, Samantha; Cho, Soo Young; Clementson-Mobbs, Sharon; D'Souza, Abigail; Dickinson, Mary; Eskandarian, Mohammad; Flenniken, Ann M.; Fuchs, Helmut; Gailus-Durner, Valerie; Heaney, Jason; Herault, Yann; de Angelis, Martin Hrabe; Hsu, Chih-Wei; Jin, Shundan; Joynson, Russell; Kang, Yeon Kyung; Kim, Haerim; Masuya, Hiroshi; Meziane, Hamid; Murray, Steve; Nam, Ki-Hoan; Noh, Hyuna; Nutter, Lauryl M. J.; Palkova, Marcela; Prochazka, Jan; Raishbrook, Miles Joseph; Riet, Fabrice; Ryan, Jennifer; Salazar, Jason; Seavey, Zachery; Seavitt, John Richard; Sedlacek, Radislav; Selloum, Mohammed; Seo, Kyoung Yul; Seong, Je Kyung; Shin, Hae-Sol; Shiroishi, Toshihiko; Stewart, Michelle; Svenson, Karen; Tamura, Masaru; Tolentino, Heather; Udensi, Uchechukwu; Wells, Sara; White, Jacqueline; Willett, Amelia; Wotton, Janine; Wurst, Wolfgang; Yoshiki, Atsushi; Int Mouse Phenotyping Consortium, Louise; Lanoue, Louise; Lloyd, K. C. Kent; Leonard, Brian C.; Roux, Michel J.; McKerlie, Colin; Moshiri, Ala Share Save
X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes Hasenbein, Tim P.; Hoelzl, Sarah; Smith, Zachary D.; Gerhardinger, Chiara; Gonner, Marion O. C.; Aguilar-Pimentel, Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Dragano, Nathalia R. V.; da Silva-Buttkus, Patricia; Garrett, Lillian; Hoelter, Sabine M.; Kraiger, Markus; Oestereicher, Manuela A.; Rathkolb, Birgit; Sanz-Moreno, Adrian; Spielmann, Nadine; Wurst, Wolfgang; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; Meissner, Alexander; Engelhardt, Stefan; Rinn, John L.; Andergassen, Daniel Share Save
Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology Kaji, Seiji; Berghoff, Stefan A.; Spieth, Lena; Schlaphoff, Lennart; Sasmita, Andrew O.; Vitale, Simona; Bueschgens, Luca; Kedia, Shreeya; Zirngibl, Martin; Nazarenko, Taisiia; Damkou, Alkmini; Hosang, Leon; Depp, Constanze; Kamp, Frits; Scholz, Patricia; Ewers, David; Giera, Martin; Ischebeck, Till; Wurst, Wolfgang; Wefers, Benedikt; Schifferer, Martina; Willem, Michael; Nave, Klaus-Armin; Haass, Christian; Arzberger, Thomas; Jaekel, Sarah; Wirths, Oliver; Saher, Gesine; Simons, Mikael Share Save
The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression (vol 15, 2194, 2024) Xu, Meng; Ito-Kureha, Taku; Kang, Hyun-Seo; Chernev, Aleksandar; Raj, Timsse; Hoefig, Kai P.; Hohn, Christine; Giesert, Florian; Wang, Yinhu; Pan, Wenliang; Zietara, Natalia; Straub, Tobias; Feederle, Regina; Daniel, Carolin; Adler, Barbara; Koenig, Julian; Feske, Stefan; Tsokos, George C.; Wurst, Wolfgang; Urlaub, Henning; Sattler, Michael; Kisielow, Jan; Wulczyn, F. Gregory; Lyszkiewicz, Marcin; Heissmeyer, Vigo Share Save
APP fragment controls both ionotropic and non-ionotropic signaling of NMDA receptors Dunot, Jade; Moreno, Sebastien; Gandin, Carine; Pousinha, Paula A.; Amici, Mascia; Dupuis, Julien; Anisimova, Margarita; Winschel, Alex; Uriot, Magalie; Petshow, Samuel J.; Mensch, Maria; Bethus, Ingrid; Giudici, Camilla; Hampel, Heike; Wefers, Benedikt; Wurst, Wolfgang; Naumann, Ronald; Ashby, Michael C.; Laube, Bodo; Zito, Karen; Mellor, Jack R.; Groc, Laurent; Willem, Michael; Marie, Helene Share Save
Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern recognition receptor activation Wang, Meiyue; Flaswinkel, Heinrich; Joshi, Abhinav; Napoli, Matteo; Masgrau-Alsina, Sergi; Kamper, Julia M.; Henne, Antonia; Heinz, Alexander; Berouti, Marleen; Schmacke, Niklas A.; Hiller, Karsten; Kremmer, Elisabeth; Wefers, Benedikt; Wurst, Wolfgang; Sperandio, Markus; Ruland, Juergen; Froehlich, Thomas; Hornung, Veit Share Save
PARK7/DJ-1 deficiency impairs microglial activation in response to LPS-induced inflammation Mogensen, Frida Lind-Holm; Sousa, Carole; Ameli, Corrado; Badanjak, Katja; Pereira, Sandro L.; Muller, Arnaud; Kaoma, Tony; Coowar, Djalil; Scafidi, Andrea; Poovathingal, Suresh K.; Tziortziou, Maria; Antony, Paul M. A.; Nicot, Nathalie; Ginolhac, Aurelien; Weisenhorn, Daniela M. Vogt; Wurst, Wolfgang; Poli, Aurelie; Nazarov, Petr V.; Skupin, Alexander; Gruenewald, Anne; Michelucci, Alessandro Share Save
Rational correction of pathogenic conformational defects in HTRA1 Beaufort, Nathalie; Ingendahl, Linda; Merdanovic, Melisa; Schmidt, Andree; Podlesainski, David; Richter, Tim; Neumann, Thorben; Kuszner, Michael; Vetter, Ingrid R.; Stege, Patricia; Burston, Steven G.; Filipovic, Anto; Ruiz-Blanco, Yasser B.; Bravo-Rodriguez, Kenny; Mieres-Perez, Joel; Beuck, Christine; Uebel, Stephan; Zobawa, Monika; Schillinger, Jasmin; Malik, Rainer; Todorov-Voelgyi, Katalin; Rey, Juliana; Roberti, Annabell; Hagemeier, Birte; Wefers, Benedikt; Mueller, Stephan A.; Wurst, Wolfgang; Sanchez-Garcia, Elsa; Zimmermann, Alexander; Hu, Xiao-Yu; Clausen, Tim; Huber, Robert; Lichtenthaler, Stefan F.; Schmuck, Carsten; Giese, Michael; Kaiser, Markus; Ehrmann, Michael; Dichgans, Martin Share Save
A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior Sen, Paromita; Ortiz, Oskar; Brivio, Elena; Menegaz, Danusa; Elliott, Laura Sotillos; Du, Ying; Ries, Clemens; Chen, Alon; Wurst, Wolfgang; Lopez, Juan Pablo; Eder, Matthias; Deussing, Jan M. Share Save
Comparative Phenotyping of Mice Reveals Canonical and Noncanonical Physiological Functions of TRα and TRβ Hoenes, Georg Sebastian; Geist, Daniela; Wenzek, Christina; Pfluger, Paul Thomas; Mueller, Timo Dirk; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; Dragano, Natalia; Garrett, Lillian; Hoelter, Sabine Maria; Rathkolb, Birgit; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Wolf, Eckhard; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Fuehrer, Dagmar; Moeller, Lars Christian Share Save
A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli Giusti, Sebastian A.; Pino, Natalia S.; Pannunzio, Camila; Ogando, Mora B.; Armando, Natalia G.; Garrett, Lillian; Zimprich, Annemarie; Becker, Lore; Gimeno, Maria L.; Lukin, Jeronimo; Merino, Florencia L.; Pardi, M. Belen; Pedroncini, Olivia; Di Mauro, Giuliana C.; Durner, Valerie Gailus; Fuchs, Helmut; de Angelis, Martin Hrabe; Patop, Ines L.; Turck, Christoph W.; Deussing, Jan M.; Weisenhorn, Daniela M. Vogt; Jahn, Olaf; Kadener, Sebastian; Hoelter, Sabine M.; Brose, Nils; Giesert, Florian; Wurst, Wolfgang; Marin-Burgin, Antonia; Refojo, Damian Share Save
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Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting Gruber, Christoph; Krautner, Lea; Bergant, Valter; Grass, Vincent; Ma, Zhe; Rheinemann, Lara; Krus, Ariane; Reinhardt, Friederike; Mazneykova, Lyupka; Rocha-Hasler, Marianne; Truong, Dong-Jiunn Jeffery; Westmeyer, Gil Gregor; Pichlmair, Andreas; Ebert, Gregor; Giesert, Florian; Wurst, Wolfgang Share Save
Implication of transcription factor FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT) Riedhammer, Korbinian M.; Nguyen, Thanh-Minh T.; Kosukcu, Can; Calzada-Wack, Julia; Li, Yong; Batzir, Nurit Assia; Saygili, Seha; Wimmers, Vera; Kim, Gwang-Jin; Chrysanthou, Marialena; Bakey, Zeineb; Sofrin-Drucker, Efrat; Kraiger, Markus; Sanz-Moreno, Adrian; Amarie, Oana V.; Rathkolb, Birgit; Klein-Rodewald, Tanja; Garrett, Lillian; Hoelter, Sabine M.; Seisenberger, Claudia; Haug, Stefan; Schlosser, Pascal; Marschall, Susan; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Wuttke, Matthias; de Angelis, Martin Hrabe; Comic, Jasmina; Dogan, Ozlem Akgun; Ozluk, Yasemin; Tasdemir, Mehmet; Agbas, Ayse; Canpolat, Nur; Orenstein, Naama; Caliskan, Salim; Weber, Ruthild G.; Bergmann, Carsten; Jeanpierre, Cecile; Saunier, Sophie; Lim, Tze Y.; Hildebrandt, Friedhelm; Alhaddad, Bader; Basel-Salmon, Lina; Borovitz, Yael; Wu, Kaman; Antony, Dinu; Matschkal, Julia; Schaaf, Christian W.; Renders, Lutz; Schmaderer, Christoph; Rogg, Manuel; Schell, Christoph; Meitinger, Thomas; Heemann, Uwe; Koettgen, Anna; Arnold, Sebastian J.; Ozaltin, Fatih; Schmidts, Miriam; Hoefele, Julia Share Save
The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression Xu, Meng; Ito-Kureha, Taku; Kang, Hyun-Seo; Chernev, Aleksandar; Raj, Timsse; Hoefig, Kai P.; Hohn, Christine; Giesert, Florian; Wang, Yinhu; Pan, Wenliang; Zietara, Natalia; Straub, Tobias; Feederle, Regina; Daniel, Carolin; Adler, Barbara; Koenig, Julian; Feske, Stefan; Tsokos, George C.; Wurst, Wolfgang; Urlaub, Henning; Sattler, Michael; Kisielow, Jan; Wulczyn, F. Gregory; Lyszkiewicz, Marcin; Heissmeyer, Vigo Share Save
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