Not logged in ENRICHED YES1 TUMOR EXPRESSION AT THE STROMAL INTERFACE IS ASSOCIATED WITH WORSE OVERALL SURVIVAL IN CLEAR CELL RENAL CELL CARCINOMA WHEN TREATED WITH FIRST-LINE IMMUNE CHECKPOINT BLOCKADE Obermayer, Alyssa; Soupir, Alex; Moran-Segura, Carlos; Echevarria, Paola Ramos; Darst, Liz; Marchion, Doug; Yoder, Sean; Balasi, Jodi; Churchman, Michelle; Singer, Eric; Kern, Sean; Zakharia, Yousef; Viscuse, Paul; Hensley, Patrick; Grass, Daniel; Dhillon, Jasreman; Mule, James; Manley, Brandon; Shaw, Timothy; Hayes, Mitchell Share Save
FGD1 splice variant as a novel biomarker for inferior clinical outcomes and development of brain and bone metastasis in clear cell renal cell carcinoma Soupir, Alex; Obermayer, Alyssa; Avasthi, Kapil; Kim, Youngchul; Miller, Justin; Hayes, Mitchell; Abreu, Nicholas; Elias, Roy; Singla, Nirmish; Churchman, Michele; Grass, Daniel; Tarhini, Ahmad; Ramos-Echevarria, Paola; Zea, Kelly; Singer, Eric A.; Kern, Sean; Zakharia, Yousef; Viscuse, Paul; Hensley, Patrick; Wang, Liang; Shaw, Timothy; Manley, Brandon Share Save
Effector T cells under hypoxia have an altered transcriptome similar to tumor-stressed T cells found in non-responsive melanoma patients Nagy, Mate Z.; Plaza-Rojas, Lourdes B.; Boucher, Justin C.; Kostenko, Elena; Austin, Anna L.; Tarhini, Ahmad A.; Chen, Zhihua; Du, Dongliang; Ojwang', Awino Maureiq E.; Davis, Joshua; Obermayer, Alyssa; Rejniak, Katarzyna A.; Shaw, Timothy, I; Guevara-Patino, Jose A. Share Save
Comprehensive genomic analysis reveals molecular heterogeneity in pediatric ALK-positive anaplastic large cell lymphoma Shaw, Timothy I.; Pounds, Stanley; Cao, Xueyuan; Ma, Jing; Palacios, Gustavo; Mason, John; Perkins, Sherrie; Wu, Gang; Fan, Yiping; Wang, Jian; Zhou, Xin; Obermayer, Alyssa; Kinney, Marsha C.; Kraveka, Jacqueline; Gross, Thomas; Sandlund, John; Zhang, Jinghui; Mullighan, Charles; Lim, Megan S.; Leventaki, Vasiliki Share Save
Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages Mandula, Jay K.; Sierra-Mondragon, Rosa A.; Jimenez, Rachel V.; Chang, Darwin; Mohamed, Eslam; Chang, Shiun; Vazquez-Martinez, Julio A.; Cao, Yu; Anadon, Carmen M.; Lee, Sae Bom; Das, Satyajit; Rocha-Munguba, Leo; Pham, Vincent M.; Li, Roger; Tarhini, Ahmad A.; Furqan, Muhammad; Dalton, William; Churchman, Michelle; Moran-Segura, Carlos M.; Nguyen, Jonathan; Perez, Bradford; Kojetin, Douglas J.; Obermayer, Alyssa; Yu, Xiaoqing; Chen, Ann; Shaw, Timothy I.; Conejo-Garcia, Jose R.; Rodriguez, Paulo C. Share Save
Pathogenic Roles for RNASET2 in Clear Cell Renal Cell Carcinoma Peak, Taylor; Tian, Yijun; Patel, Aman; Shaw, Tim; Obermayer, Alyssa; Laborde, Jose; Kim, Youngchul; Johnson, Joseph; Stewart, Paul; Fang, Bin; Teer, Jamie K.; Koomen, John; Berglund, Anders; Marchion, Doug; Francis, Natasha; Echevarria, Paola Ramos; Dhillon, Jasreman; Clark, Noel; Chang, Andrew; Sexton, Wade; Zemp, Logan; Chahoud, Jad; Wang, Liang; Manley, Brandon Share Save
Analysis of clonal heterogeneity within paired primary and metastatic tumor samples of patients with solid tumors and implications for neoantigen-based personalized cancer vaccines Obermayer, Alyssa; Shaw, Timothy; Chang, Darwin; Davis, Joshua; Teer, Jamie K.; Yu, Xiaoqing; Wang, Xuefeng; Hedges, Dale; Tan, Aik Choon; Rounbehler, Robert; Naqash, Abdul Rafeh; Gatti-Mays, Margaret; Ratan, Aakrosh; McCarter, Martin; Colman, Howard; Puzanov, Igor; Arnold, Susanne; Churchman, Michelle; Hwu, Patrick; Dalton, William; Weiner, George; Conejo-Garcia, Jose; Rodriguez, Paulo C.; Salhia, Bodour; Tarhini, Ahmad A. Share Save
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CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax Neault, Mathieu; Lebert-Ghali, Charles-Etienne; Fournier, Marilaine; Capdevielle, Caroline; Garfinkle, Elizabeth A. R.; Obermayer, Alyssa; Cotton, Anitria; Boulay, Karine; Sawchyn, Christina; St-Amand, Sarah; Nguyen, Kamy H.; Assaf, Beatrice; Mercier, Francois E.; Delisle, Jean-Sebastien; Drobetsky, Elliot A.; Hulea, Laura; Shaw, Timothy I.; Zuber, Johannes; Gruber, Tanja A.; Melichar, Heather J.; Mallette, Frederick A. Share Save
Bcl11b sustains multipotency and restricts effector programs of intestinal-resident memory CD8+T cells Helm, Eric Y.; Zelenka, Tomas; Cismasiu, Valeriu B.; Islam, Shamima; Silvane, Leonardo; Zitti, Beatrice; Holmes, Tim D.; Drashansky, Theodore T.; Kwiatkowski, Alexander J.; Tao, Christine; Dean, Joseph; Obermayer, Alyssa N.; Chen, Xianghong; Keselowsky, Benjamin G.; Zhang, Weizhou; Huo, Zhiguang; Zhou, Liang; Sheridan, Brian S.; Conejo-Garcia, Jose R.; Shaw, Timothy I.; Bryceson, Yenan T.; Avram, Dorina Share Save
An integrated immune signature predictive of adjuvant immunotherapeutic benefits for high-risk melanoma Obermayer, Alyssa N.; Shaw, Timothy I.; Lee, Sandra J.; Hodi, F. Stephen; LaFramboise, William A.; Storkus, Walter; Karunamurthy, Arivarasan D.; Hwu, Patrick; Streicher, Howard; Chen, Dung-Tsa; Kirkwood, John M.; Tarhini, Ahmad A. Share Save
Malignant Progression of an Ancestral Bone Marrow Clone Harboring a CIC-NUTM2A Fusion in Isolated Myeloid Sarcoma Kamens, Jennifer L.; Dang, Jinjun; Shaw, Timothy I.; Gout, Alexander M.; Newman, Scott; Hagiwara, Kohei; Smith, Amelia M. R.; Obermayer, Alyssa N.; Aldridge, Sarah; Ma, Jing; Zhang, Yang; Wu, Gang; Leventaki, Vasiliki; Santiago, Teresa; Raimondi, Susana; Nakitandwe, Joy; Pappo, Alberto; Li, Chunliang; Zhang, Jinghui; Gruber, Tanja A. Share Save
TARGETING OF NOTCH LIGAND JAGGED2 IN LUNG CANCER CELLS DRIVES ANTI-TUMOR IMMUNITY VIA NOTCH-INDUCED FUNCTIONAL REPROGRAMMING OF TUMOR-ASSOCIATED MACROPHAGES Mandula, J.; Sierra-Mondragon, Rosa; Chang, Darwin; Jimenez, Rachel; Mohamed, Eslam; Trillo, Jimena; Obermayer, Alyssa; Moran-Segura, Carlos; Satyajit, Das; Vazquez-Martinez, Julio; Shaw, Timothy; Conejo-Garcia, Jose; Rodriguez, Paulo Share Save
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