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陈

陈兴栋｜Xingdong Chen

fudan universityEmail: xingdongchen@fudan.edu.cn
H-index:39
Citation Count:6,606
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Biography

2006年和2009年分获山东大学预防医学学士和流行病学硕士学位，2012年获复旦大学遗传学博士学位。2013-2015年和2016-2019年分别在瑞典卡罗林斯卡医学院和复旦大学从事博士后研究。2015-2017年任瑞典卡罗林斯卡医学院访问博士后，2015-2019年任复旦大学泰州健康科学研究院副院长，2020年至今任复旦大学泰州健康科学研究院执行院长。任全国生物样本标准化技术委员会（SAC/TC559）委员、首届中国研究型医院学会临床数据与样本资源库专业委员会信息学组委员、全国医药健康数据处理专业委员会委员，先后担任International journal of epidemiology、Alzheimer's & Dementia、International journal of cancer等杂志审稿人。近5年以第一及通讯作者在Journal of Hepatology、Alzheimer's & Dementia、Journal of Thoracic Oncology、Nature Communications等本领域高水平学术期刊发表SCI论文60余篇，申请发明专利3项，获软件著作权5项，出版专著2部，参与立项卫生健康信息团体标准2项。承担和参与多项国家重点研发计划、国家自然科学基金、863计划、科技支撑计划、国际合作专项等国家和省部级项目。入选江苏省第十六批“六大人才高峰”高层次人才选拔培养资助计划、2020年上海高校特聘教授（东方学者）岗位计划、2021年国家自然科学基金优秀青年基金。

Education

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Work Experience

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Honors & Awards

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Towards a Compositional Framework for Describing Human Phenotypes

描述人类表型的组合框架研究

Advanced Science
IF14.1
2026-09-240
OAAI
Wanting Hu; Yunchao Ling; Xinyue Hu; Wei Chen; Rong Zhou; Xinhao Zhuang; Yanfeng Jiang; Jialu Zhao; Xingdong Chen; Jingchun Luo; Li Jin; Guoqing Zhang
Selection and prediction of targeted serum protein biomarkers for early diagnosis of esophageal squamous cell carcinoma

食管鳞状细胞癌早期诊断靶向血清蛋白生物标志物的选择与预测

BMC Cancer
IF3.4
2026-09-080
OAAI
Tongchao Zhang; Ziqian Song; Jinyu Man; Xiaolin Yin; Xuening Zhang; Zilin Li; Zhen Li; Weimin Ye; Xingdong Chen; Xiaorong Yang; Ming Lu
Galectin-3 worsens microglia-mediated synaptic engulfment and neuroinflammatory responses after traumatic brain injury

Galectin-3加剧创伤性脑损伤后小胶质细胞介导的突触吞噬和神经炎症反应

Journal of Neuroinflammation
IF10.1
2026-08-290
OA
Xingdong Chen; Jingjing Wu; Yiyang Chen; Yuqing Wang; Ziyu Shi; Leilei Mao; Hong Shi; Yanqin Gao
Deep Immunophenotyping Unravels the Double Negative T cells and PD-1-Mediated Inflammatory Exhaustion in Ankylosing Spondylitis

深度免疫表型分析揭示了强直性脊柱炎中双重阴性T细胞和PD-1介导的炎症性耗竭

Phenomics
IF6.2
2026-08-130
OA
Lu Bai; Jian Gao; Yunyun Xu; Yuexin Yu; Jing Liu; Mathias Hochgerner; Hejian Zou; Xingdong Chen; Feng Qian; Hongjun He; Jiucun Wang
Multi-omics dissection of MASLD reveals divergent pathways to systemic diseases and targets for prevention

多组学解析MASLD揭示了系统性疾病的分歧途径及预防靶点

Metabolism-Clinical and Experimental
IF11.9
2026-08-110
PRE
Yuxuan Weng; Mingyi Du; Tianhao Wu; Linyao Lu; Yanfeng Jiang; Chen Suo; Li Jin; Tiejun Zhang; Xingdong Chen; Zhenqiu Liu
BHOD: a bone health optimized dietary pattern designed for osteoporosis prevention

BHOD：一种针对骨质疏松症预防的骨健康优化膳食模式

npj Science of Food
IF7.8
2026-07-010
OAAI
Yi Zheng; Yucan Li; Yawen Gao; Xiao Liang; Jincheng Li; Chen Suo; Yanfeng Jiang; Li Jin; Kelin Xu; Xingdong Chen
Causal Associations of Red Cell Distribution Width with Rheumatoid Arthritis and Congestive Heart Failure: A Phenome-Wide Mendelian Randomization Study

红细胞分布宽度与类风湿关节炎和充血性心力衰竭的因果关系：一项全表型孟德尔随机化研究

Phenomics
IF6.2
2026-03-260
PRE
Jing Lei; Zhenqiu Liu; Renjia Zhao; Yanfeng Jiang; Kelin Xu; Tiejun Zhang; Chen Suo; Xingdong Chen
Association of Serum Elements and Urinary Arsenic Species with Esophageal Cancer Risk in a Low Metal Exposure Area: A Case–Cohort Study in China

血清元素和尿砷形态与食管癌风险的相关性：一项在中国低金属暴露地区的病例-队列研究

Phenomics
IF6.2
2026-03-230
PRE
Qingling Su; Zesen Gao; Yan Wu; Yang Ouyang; Shanshan Du; Hongwei Zhao; Weidong Qu; Yanfeng Jiang; Chen Suo; Ziyu Yuan; Xingdong Chen; Ruimei Feng; Weimin Ye
Changes of Helicobacter pylori Infection Status and Risk of Precancerous Lesions: A Prospective Cohort Study in Chinese Population

幽门螺杆菌感染状态的变化与癌前病变风险：一项中国人群的前瞻性队列研究

Helicobacter
IF4.3
2026-03-050
PRE
Xufei Xing; Renjia Zhao; Zixuan Cui; Qiaoyi Xu; Ziyu Yuan; Kelin Xu; Tiejun Zhang; Zhenqiu Liu; Yanfeng Jiang; Ming Lu; Weimin Ye; Chen Suo; Xingdong Chen
Cross-trait genomic modeling reveals the polygenic architecture and systemic impact of MASLD

跨性状基因组学建模揭示了MASLD的多基因结构和系统性影响

Science Advances
IF12.5
2026-02-130
OA
Mingyi Du; Huangbo Yuan; Tianhao Wu; Yanfeng Jiang; Chen Suo; Li Jin; Tiejun Zhang; Zhenqiu Liu; Xingdong Chen
Cerebral Small Vessel Disease as a Novel Risk Indicator for Periodontitis Progression

脑小血管病作为牙周炎进展的新型风险指标

International Dental Journal
IF3.7
2026-02-100
OAAI
Shaobo Han; Xinyu Chen; Fei Li; Xingdong Chen; Mei Cui; Katherine Chiu Man Leung; Yanfeng Jiang; Edward Chin Man Lo; Haixia Lu
Multilevel pathways to esophageal cancer: Population attributable risks of modifiable exposures, surrogate blood biomarkers, and genetic susceptibility, and the mediation effects based on a 10-year prospective cohort study

食管癌的多层次路径：基于10年前瞻性队列研究可改变暴露因素的归因风险、血液替代生物标志物和遗传易感性的中介效应

International Journal of Cancer
IF4.7
2026-02-010
PRE
Cui, Zixuan; Zhao, Yidan; Xu, Qiaoyi; Zhao, Renjia; Yuan, Huangbo; Zhang, Tiejun; Suo, Chen; Chen, Xingdong
Associations between plasma ANGPTL4 levels and the risk of 24 cancers: a prospective cohort study

血浆ANGPTL4水平与24种癌症风险之间的关联：一项前瞻性队列研究

Cytokine
IF3.7
2025-12-200
PRE
Xi Cheng; Shuzhen Zhao; Mingyi Du; Chengnan Guo; Xingdong Chen; Tiejun Zhang; Zhenqiu Liu
Relationships among dietary patterns and heterogeneous biological aging at system and organ-specific levels and mortality risks

膳食模式与系统及器官特异性水平上的异质性生物衰老以及死亡风险之间的关系

npj Science of Food
IF7.8
2025-12-120
OAAI
Xinming Xu; Yucan Li; Yunxin Wang; Berty Ruping Song; Jiada Zhan; Geng Zong; Xingdong Chen; Kelin Xu; Liang Sun; Chengwu Feng; Alice H. Lichtenstein; Xiang Gao
Synergistic and heterogeneous aging using composite phenotypes and multiple organ systems aging clocks

协同作用与异质性衰老，使用复合表型及多器官系统衰老时钟

Communications Medicine
IF6.3
2025-12-010
OAAI
Yucan Li; Xinming Xu; Yi Zheng; Rui Li; Xin Zhang; Jiacheng Wang; Ningxin Gao; Jianming Wang; Yawen Wang; Jialin Li; Jincheng Li; Danke Wang; Zhenqiu Liu; Mei Cui; Yanfeng Jiang; Yingzhe Wang; Chen Suo; Tiejun Zhang; Kelin Xu; Xingdong Chen
The comprehensive oral microbiome landscape unveils its interplay with poor oral health in esophageal squamous cell carcinoma risk

全面的口腔微生物组景观揭示了其与食管鳞状细胞癌风险中不良口腔健康的相互作用

Cell Reports Medicine
IF10.6
2025-11-050
OAAI
Peipei Gao; Huangbo Yuan; Zhendong Mei; Xiaolin Yin; Yixin Zeng; Zhenqiu Liu; Xiaorong Yang; Jiangli Xue; Zidong Liu; Yanfeng Jiang; Weimin Ye; Ming Lu; Chen Suo; Xingdong Chen
Immune, blood-brain barrier, and metabolic biomarkers mediate gut-brain axis crosstalk in alzheimer’s disease

免疫、血脑屏障和代谢生物标志物介导阿尔茨海默病中肠-脑轴的相互作用

Biomarker Research
IF11.5
2025-10-300
OAAI
Jincheng Li; Ziyu Yuan; Jialin Li; Zhenqiu Liu; Yingzhe Wang; Mei Cui; Chen Suo; Li Jin; Ding Ding; Xingdong Chen; Yanfeng Jiang
Urinary mycotoxins and esophageal cancer risk in China: A case-cohort study

尿真菌毒素与食管癌风险在中国：一项病例-队列研究

International Journal of Cancer
IF4.7
2025-10-200
PRE
Qingling Su; Ruimei Feng; Shanshan Du; Hongwei Zhao; Yanfeng Jiang; Chen Suo; Ziyu Yuan; Xingdong Chen; Yan Wu; Weimin Ye
Associations of cholinergic white matter hyperintensity volume with cognitive decline and incident dementia in older adults: a cohort study

胆碱能白质高信号体积与认知衰退及新发痴呆的关联：一项队列研究

BMC Geriatrics
IF3.8
2025-10-120
OAAI
Heyang Lu; Rui Li; Jialin Li; Kelin Xu; Yanfeng Jiang; Yingzhe Wang; Xingdong Chen; Mei Cui
Cross-sectional and longitudinal associations of circulating bile acids and dementia: a systematic review

循环胆汁酸与痴呆的横断面和纵向关联：一项系统综述

GeroScience
IF5.4
2025-07-230
PRE
Yasi Zhang; Jialin Li; Jincheng Li; Yingzhe Wang; Mei Cui; Wenyan Li; Xingdong Chen; Yanfeng Jiang

Research Directions

大型队列建设重大慢性疾病的分子流行病学和遗传学研究消化系统恶性肿瘤分子流行病学遗传肿瘤发生发展的机制表型组研究
李金 cover
李金
H-index:149Papers:4,499Citations:12.8万
索
索晨
H-index:39Papers:205Citations:9,014
张
张铁军
H-index:33Papers:246Citations:5,143
蒋
蒋艳峰
H-index:31Papers:387Citations:5,235
刘
刘振球
H-index:38Papers:208Citations:6,265
K
Kelin Xu
H-index:19Papers:171Citations:1,669
M
Mei Cui
H-index:38Papers:219Citations:7,032
Y
Yingzhe Wang
H-index:34Papers:228Citations:3,209
W
Weimin Ye
H-index:90Papers:771Citations:3.0万
袁子彧 cover
袁子彧
H-index:26Papers:78Citations:2,537