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Erik I. Tucker

Aronora Inc.

31H-index
120Paper Count
3.1KCitation Count
Published Papers 47
Publication Date
The Factor XIa Antibody Osocimab Strongly Inhibits Clotting in Extracorporeal Circuits with human blood and in baboons
err2025-06-01
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errEslam Samaha; Michael Schwameis; Sabine Schranz; Katarina D. Kovacevic; Bruno Watschinger; Martin Stoiber; Christopher Wolf; Michael Wallisch; András Gruber; Erik I. Tucker; Anja Buchmüller; Bernd Jilma
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The physicochemical properties of lipopolysaccharide chemotypes regulate activation of the contact pathway of blood coagulation
err2025-01-01
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errLira, Andre L.; Taskin, Berk; Puy, Cristina; Keshari, Ravi S.; Silasi, Robert; Pang, Jiaqing; Aslan, Joseph E.; Shatzel, Joseph J.; Lorentz, Christina U.; Tucker, Erik I.; Schmaier, Alvin H.; Gailani, David; Lupu, Florea; Mccarty, Owen J. T.
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Safety and tolerability of the protein C activator AB002 in end-stage renal disease patients on hemodialysis: a randomized phase 2 trial
err2024-07-26
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errVerbout, Norah G.; Lorentz, Christina U.; Markway, Brandon D.; Wallisch, Michael; Marbury, Thomas C.; Di Cera, Enrico; Shatzel, Joseph J.; Gruber, Andras; Tucker, Erik I.
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Pharmacologic targeting of coagulation factors XII and XI by monoclonal antibodies reduces thrombosis in nitinol stents under flow
err2024-05-01
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errKeeling, Novella M.; Wallisch, Michael; Johnson, Jennifer; Le, Hillary H.; Vu, Helen H.; Jordan, Kelley R.; Puy, Cristina; Tucker, Erik I.; Nguyen, Khanh P.; McCarty, Owen J. T.; Aslan, Joseph E.; Hinds, Monica T.; Anderson, Deirdre E. J.
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Role Of Divalent Cations In The Enzymatic Activation Of Coagulation Factor XII By Lipopolysaccharides
err2024-05-01
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PREAI
errLiu, Ting; da Sliva, Andre Lira; Lorentz, Christina U.; Tucker, Erik; Lupu, Florea; Gailani, David; Puy, Cristina; McCarty, Owen J.
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Activation of coagulation FXI promotes endothelial inflammation and amplifies platelet activation in a nonhuman primate model of hyperlipidemia
err2024-01-01
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errKohs, Tia C. L.; Vu, Helen H.; Jordan, Kelley R.; Parra-Izquierdo, Ivan; Hinds, Monica T.; Shatzel, Joseph J.; Kievit, Paul; Morgan, Terry K.; Yunga, Samuel Tassi; Ngo, Thuy T. M.; Aslan, Joseph E.; Wallisch, Michael; Lorentz, Christina U.; Tucker, Erik I.; Gailani, David; Lindner, Jonathan R.; Puy, Cristina; Mccarty, Owen J. T.
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Factor XI Inhibition for the Prevention of Catheter-Associated Thrombosis in Patients With Cancer Undergoing Central Line Placement: A Phase 2 Clinical Trial
err2024-01-01
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errPfeffer, Michael A.; Kohs, Tia C. L.; Vu, Helen H.; Jordan, Kelley R.; Wang, Jenny Si Han; Lorentz, Christina U.; Tucker, Erik I.; Puy, Cristina; Olson, Sven R.; Deloughery, Thomas G.; Hinds, Monica T.; Keshari, Ravi S.; Gailani, David; Lupu, Florea; Mccarty, Owen J. T.; Shatzel, Joseph J.
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Cytoprotective E-WE thrombin reduces disease severity in a murine model of relapsing-remitting multiple sclerosis
err2024-01-01
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PREAI
errVerbout, Norah G.; Su, Weiping; Pham, Peter; Jordan, Kelley R.; Kohs, Tia C. L.; Tucker, Erik I.; McCarty, Owen J. T.; Sherman, Larry S.
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Factor XI Inhibition With Heparin Reduces Clot Formation in Simulated Pediatric Extracorporeal Membrane Oxygenation
err2023-10-06
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PREAI
errMeyer, Andrew D.; Thorpe, Catherine R.; Fraker, Tamara; Cancio, Tomas; Rocha, Jeanette; Willis, R. Patrick; Cap, Andrew P.; Gailani, David; Shatzel, Joseph J.; Tucker, Erik I.; McCarty, Owen J. T.
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Pharmacological targeting of coagulation factor XI attenuates experimental autoimmune encephalomyelitis in mice
err2023-06-21
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errKohs, Tia C. L.; Fallon, Meghan E.; Oseas, Ethan C.; Healy, Laura D.; Tucker, Erik I.; Gailani, David; McCarty, Owen J. T.; Vandenbark, Arthur A.; Offner, Halina; Verbout, Norah G.
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Thrombogenic potential of picomolar coagulation factor XIa is mediated by thrombin wave propagation
err2023-06-05
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errParunov, Leonid A.; Liang, Yideng; Lu, Qijin; Shibeko, Alexey M.; Tucker, Erik I.; Lee, Timothy K.; Ataullakhanov, Fazoil I.; Scott, Dorothy E.; Ovanesov, Mikhail, V
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Mechanism By Which Coagulation Factor XI Regulates Endothelial Cell Permeability And Barrier Function In Vitro And In Vivo
err2023-05-01
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PREAI
errPuy, Cristina; Lorentz, Christina U.; Tucker, Erik; Lupu, Florea; Gailani, David; McCarty, Owen J.
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Titanium is a potent inducer of contact activation: implications for intravascular devices
err2023-05-01
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errLitvak, Maxim; Shamanaev, Aleksandr; Zalawadiya, Sandip; Matafonov, Anton; Kobrin, Anton; Feener, Edward P.; Wallisch, Michael; Tucker, Erik I.; McCarty, Owen J. T.; Gailani, David
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Pharmacological reduction of coagulation factor XI reduces macrophage accumulation and accelerates deep vein thrombosis resolution in a mouse model of venous thrombosis
err2022-09-01
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errJordan, Kelley R.; Wyatt, Cory R.; Fallon, Meghan E.; Woltjer, Randy; Neuwelt, Edward A.; Cheng, Quifang; Gailani, David; Lorentz, Christina; Tucker, Erik, I; McCarty, Owen J. T.; Hinds, Monica T.; Nguyen, Khanh P.
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Revised model of the tissue factor pathway of thrombin generation: Role of the feedback activation of FXI
err2022-06-01
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errLakshmanan, Hari Hara Sudhan; Estonilo, Aldrich; Reitsma, Stephanie E.; Melrose, Alexander R.; Subramanian, Jayaram; Zheng, Tony J.; Maddala, Jeevan; Tucker, Erik, I; Gailani, David; McCarty, Owen J. T.; Jurney, Patrick L.; Puy, Cristina
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Cross-Talk between the Complement Pathway and the Contact Activation System of Coagulation: Activated Factor XI Neutralizes Complement Factor H
err2021-04-15
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errPuy, Cristina; Pang, Jiaqing; Reitsma, Stephanie E.; Lorentz, Christina U.; Tucker, Erik, I; Gailani, David; Gruber, Andras; Lupu, Florea; McCarty, Owen J. T.
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Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low-density lipoprotein receptor-deficient mice
err2021-04-01
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errNgo, Anh T. P.; Jordan, Kelley R.; Mueller, Paul A.; Hagen, Matthew W.; Reitsma, Stephanie E.; Puy, Cristina; Revenko, Alexey S.; Lorentz, Christina U.; Tucker, Erik I.; Cheng, Quifang; Hinds, Monica T.; Fazio, Sergio; Monia, Brett P.; Gailani, David; Gruber, Andras; Tavori, Hagai; McCarty, Owen J. T.
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Role of platelets in regulating activated coagulation factor XI activity
err2021-03-01
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errReitsma, Stephanie E.; Pang, Jiaqing; Raghunathan, Vikram; Shatzel, Joseph J.; Lorentz, Christina U.; Tucker, Erik, I; Gruber, Andras; Gailani, David; McCarty, Owen J. T.; Puy, Cristina
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The contact activation system as a potential therapeutic target in patients with COVID-19
err2020-05-01
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errShatzel, Joseph J.; DeLoughery, Emma P.; Lorentz, Christina U.; Tucker, Erik I.; Aslan, Joseph E.; Hinds, Monica T.; Gailani, David; Weitz, Jeffrey I.; McCarty, Owen J. T.; Gruber, Andras
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Antibody inhibition of contact factor XII reduces platelet deposition in a model of extracorporeal membrane oxygenator perfusion in nonhuman primates
err2020-02-01
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errWallisch, Michael; Lorentz, Christina U.; Lakshmanan, Hari H. S.; Johnson, Jennifer; Carris, Marschelle R.; Puy, Cristina; Gailani, David; Hinds, Monica T.; McCarty, Owen J. T.; Gruber, Andras; Tucker, Erik, I
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