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J

John H. Griffin

the scripps research institute

101H-index
750Paper Count
3.5WCitation Count
Published Papers 199
Publication Date
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Activated Protein C and the Retina: From Physiology to Therapeutic Potential
errInternational Journal of Molecular Sciences
IF4.9
err2026-02-28
err0
errOAAI
errAlon Zahavi; Sarina Levy-Mendelovich; John H. Griffin; Tami Livnat
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Correction: Activated protein C ameliorates diabetes-induced atherosclerosis by sustaining macrophage efferocytosis
errCardiovascular Diabetology
IF10.6
err2026-01-19
err0
errOAAI
errSaira Ambreen; Amna Arif; Saikal Shamkeeva; Ahmed Elwakiel; Surinder Pal; Shihai Jiang; Muhammad Asad Farhan; Zuhir Halloul; John H. Griffin; Berend Isermann; Khurrum Shahzad
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EPCR-mediated endogenous and therapeutic transport of activated protein C across the blood–retina barrier protects the retina
errJournal of Thrombosis and Haemostasis
IF5
err2025-11-19
err0
PREAI
errTami Livnat; Ivan Budnik; Yael Nisgav; Rima Dardik; Einat Avishai; Sheli Rose Gonen; Alon Zahavi; José A. Fernández; Valery Golderman; Zehavit Goldberg; Gili Kenet; John H. Griffin; Sarina Levy-Mendelovich
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Activated protein C ameliorates diabetes-induced atherosclerosis by sustaining macrophage efferocytosis
errCardiovascular Diabetology
IF10.6
err2025-10-15
err0
errOAAI
errSaira Ambreen; Amna Arif; Saikal Shamkeeva; Ahmed Elwakiel; Surinder Pal; Shihai Jiang; Muhammad Asad Farhan; Zuhir Halloul; John H. Griffin; Berend Isermann; Khurrum Shahzad
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errSave
A Bivalent Protease-Activated Receptor-Derived Peptide Mimics Neuronal Anti-Apoptotic Activity of Activated Protein C
errBioengineering 2025, Vol. 12, Page 899
IF3.7
err2025-08-22
err0
PREAI
errAbhay Sagare; Youbin Kim; Kassandra Kisler; Ruslan Rust; William J. Mack; José A. Fernández; Berislav V. Zlokovic; John H. Griffin
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Restoration of branched chain amino acid catabolism improves kidney function in preclinical cardiovascular-kidney-metabolic syndrome models
errKidney International
IF12.6
err2025-05-21
err0
errOAAI
errEliza Bollinger; George Williams; Mary E. Piper; Kimberly Steen; Kelly Tam Neale; Xian Chen; Mackenzie Marshall; Srinath Jagarlapudi; Yasaman Jami-Alahmadi; Pierre M. Jean-Beltran; LouJin Song; Joshua Chiou; Frank Geoly; Sarah R. Vargas; Ying Zhang; Elaine Kuang; Daniel Callahan; John C. Stansfield; Max Russo; John Griffin; Zhongyuan Sun; Melissa R. Miller; Craig L. Hyde; Michelle F. Clasquin; Katherine Hales; Natalie A. Daurio; Justin D. Crane; Dinesh Hirenallur-Shanthappa; John Groarke; Bei B. Zhang; Rachel J. Roth Flach
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Enhancing hemostasis potency in hemophilia with a small interfering ribonucleic acid targeting protein S
errJournal of Thrombosis and Haemostasis
IF5
err2025-03-26
err0
PREAI
errRaja Prince Eladnani; Ute Schaeper; Rim Diab; Julia Aretz; Kristina Vrotniakaite-Bajerciene; Sara Çaku; Rafika Yasmin; Bojun Li; Maria Desiré Reina Caro; Sibylle Dames; Mona Eisermann; Kathrin Löffler; Alberto Martinez; Bas de Laat; Justine Brodard; Alessandro Casini; Johanna A. Kremer Hovinga; Ramanjaneyulu Allam; José A. Fernández; John H. Griffin; Anne Angelillo-Scherrer
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Hepatocyte-independent PAR1-biased signaling controls liver pathology in experimental obesity
errJOURNAL OF THROMBOSIS AND HAEMOSTASIS
IF5
err2024-11-01
err0
PREAI
errCline, Holly; Wei, Zimu; Groeneveld, Dafna J.; Hix, Jeremy M. L.; Xu, Xiao; Flick, Matthew J.; Palumbo, Joseph S.; Poole, Lauren G.; Dockendorff, Chris; Griffin, John H.; Luyendyk, James P.
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Diabetes and Driving: A Statement of the American Diabetes Association
errDIABETES CARE
IF16.6
err2024-10-21
err0
errOAAI
errCox, Daniel J.; Frier, Brian M.; Bruggeman, Brittany; Durrani, Timur; ElSayed, Nuha A.; Bannuru, Raveendhara R.; Fischer, Aaron; Griffin Jr, John; Kohrman, Daniel B.; May, Anthony; Sherman, Jennifer
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An orthosteric/allosteric bivalent peptide agonist comprising covalently linked protease-activated receptor-derived peptides mimics in vitro and in vivo activities of activated protein C
errJOURNAL OF THROMBOSIS AND HAEMOSTASIS
IF5
err2024-07-01
err1
errOAAI
errHealy, Laura D.; Fernandez, Jose A.; Aiolfi, Roberto; Mosnier, Laurent O.; Griffin, John H.
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Cytoprotective 3K3A-activated protein C and plasma: A comparison of therapeutics for the endotheliopathy of trauma
errJOURNAL OF TRAUMA AND ACUTE CARE SURGERY
IF3.7
err2024-05-27
err0
PREAI
errThielen, Otto; Stafford, Preston; Debot, Margot; Kelher, Marguerite; Mitra, Sanchayita; Hallas, William; Gallagher, Lauren T.; Schaid, Terry; Stocker, Benjamin; Ramser, Benjamin; D'Alessandro, Angelo; Hansen, Kirk; Silliman, Christopher C.; Moore, Ernest; Mosnier, Laurent; Griffin, John; Cohen, Mitchell
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Characterization Of Interactions Between Skeletal Muscle Myosin And Activated Factor XI
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2024-05-01
err0
PREAI
errYang, Chih-Jen; Griffin, John H.; Deguchi, Hiroshi; Gailani, David; McCarty, Owen J.; Puy, Cristina
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Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma
errMETABOLITES
IF3.7
err2024-04-24
err0
errOAAI
errBansal, Shivani; Li, Yaoxiang; Bansal, Sunil; Klotzbier, William; Singh, Baldev; Jayatilake, Meth; Sridharan, Vijayalakshmi; Fernandez, Jose A.; Griffin, John H.; Weiler, Hartmut; Boerma, Marjan; Cheema, Amrita K.
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Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage
errNATURE MEDICINE
IF50
err2024-03-20
err1
errOAAI
errCheng, Tong; Petraglia, Anthony. L.; Li, Zhang; Thiyagarajan, Meenakshisundaram; Zhong, Zhihui; Wu, Zhenhua; Liu, Dong; Maggirwar, Sanjay. B.; Deane, Rashid; Fernandez, Jose. A.; LaRue, Barbra; Griffin, John. H.; Chopp, Michael; Zlokovic, Berislav., V
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RETRACTION: Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C (Retraction of Vol 10, Pg 1379, 2004)
errNATURE MEDICINE
IF50
err2024-03-20
err0
errOAAI
errLiu, Dong; Cheng, Tong; Guo, Huang; Fernandez, Jose A.; Griffin, John H.; Song, Xiaomei; Zlokovic, Berislav V.
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A recombinant signalling-selective activated protein C that lacks anticoagulant activity is efficacious and safe in cutaneous wound preclinical models
errWOUND REPAIR AND REGENERATION
IF3.4
err2024-01-03
err3
PREAI
errZhao, Ruilong; Xue, Meilang; Lin, Haiyan; Smith, Margaret; Liang, Helena; Weiler, Hartmut; Griffin, John H.; Jackson, Christopher J.
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Activated Protein C Prevents Neuronal Apoptosis via Protease Activated Receptors 1 and 3
errNEURON
IF15
err2023-12-01
err0
errOAAI
errGuo, Huang; Liu, Dong; Gelbard, Harris; Cheng, Tong; Insalaco, Rae; Fernandez, Jose A.; Griffin, John H.; V. Zlokovic, Berislav
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Mitigation of trauma-induced endotheliopathy by activated protein C: A potential therapeutic for postinjury thromboinflammation
errJOURNAL OF TRAUMA AND ACUTE CARE SURGERY
IF3.7
err2023-09-21
err5
PREAI
errThielen, Otto; Mitra, Sanchayita; Debot, Margot; Schaid, Terry; Hallas, William; Gallagher, Lauren T.; Erickson, Christopher; Cralley, Alexis; Stafford, Preston; Silliman, Christopher; D'Alessandro, Angelo; Hansen, Kirk; Sauaia, Angela; Moore, Ernest; Mosnier, Laurent; Griffin, John; Cohen, Mitchell
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Analysis of brain edema in RHAPSODY
errINTERNATIONAL JOURNAL OF STROKE
IF8.7
err2023-07-16
err3
PREAI
errSchleicher, Riana L.; Vorasayan, Pongpat; McCabe, Megan E.; Bevers, Matthew B.; Davis, Thomas P.; Griffin, John H.; Hinduja, Archana; Jadhav, Ashutosh P.; Lee, Jin-Moo; Sawyer Jr, Robert N.; Zlokovic, Berislav, V; Sheth, Kevin N.; Fedler, Janel K.; Lyden, Patrick; Kimberly, W. Taylor
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Thrombin-mediated activation of PAR1 enhances doxorubicin-induced cardiac injury in mice
errBLOOD ADVANCES
IF7.1
err2023-05-10
err4
errOAAI
errGrover, Steven P.; Bharathi, Vanthana; Posma, Jens J.; Griffin, John H.; Palumbo, Joseph S.; Mackman, Nigel; Antoniak, Silvio
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Research Directions

No research directions
Co-authors
Cooperation Journals
P
Peter Carmeliet
H-index: 192 · Papers: 1.4K
M
Michael A. Matthay
H-index: 169 · Papers: 1.3K
D
Don W. Cleveland
H-index: 165 · Papers: 525
I
Inder M. Verma
H-index: 153 · Papers: 571
E
Ernest E. Moore
H-index: 153 · Papers: 2.8K
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