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H

Heini W. Dirr

University of Witwatersrand

35H-index
139Paper Count
4.3KCitation Count
Published Papers 27
Publication Date
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An empirical and theoretical description of Schistosoma japonicum glutathione transferase inhibition by bromosulfophthalein and indanyloxyacetic acid 94
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2021-01-01
err10
PREAI
errPooe, Kagiso; Worth, Roland; Iwuchukwu, Emmanuel Amarachi; Dirr, Heini W.; Achilonu, Ikechukwu
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Double trouble? Gag in conjunction with double insert in HIV protease contributes to reduced DRV susceptibility
errBIOCHEMICAL JOURNAL
IF4.3
err2019-01-31
err5
PREAI
errWilliams, Alison; Basson, Adriaan; Achilonu, Ikechukwu; Dirr, Heini W.; Morris, Lynn; Sayed, Yasien
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V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity
errCELL REPORTS
IF6.9
err2018-12-01
err23
errOAAI
errvan Eeden, Charmaine; Wibmer, Constantinos Kurt; Scheepers, Cathrine; Richardson, Simone I.; Nonyane, Molati; Lambson, Bronwen; Mkhize, Nonhlanhla N.; Vijayakumar, Balakrishnan; Sheng, Zizhang; Stanfield-Oakley, Sherry; Bhiman, Jinal N.; Bekker, Valerie; Hermanus, Tandile; Mabvakure, Batsirai; Ismail, Arshad; Moody, M. Anthony; Wiehe, Kevin; Garrett, Nigel; Karim, Salim Abdool; Dirr, Heini; Fernandes, Manuel A.; Sayed, Yasien; Shapiro, Lawrence; Ferrari, Guido; Haynes, Barton F.; Moore, Penny L.; Morris, Lynn
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A conserved cation binding site in the DNA binding domain of forkhead box transcription factors regulates DNA binding by FOXP2
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2018-11-01
err4
PREAI
errMorris, Gavin; Pahad, Naadira; Dirr, Heini W.; Fanucchi, Sylvia
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Structural and biochemical characterization of Plasmodium falciparum Hsp70-x reveals functional versatility of its C-terminal EEVN motif
errPROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
IF2.8
err2018-09-29
err32
errOAAI
errMabate, Blessing; Zininga, Tawanda; Ramatsui, Lebogang; Makumire, Stanley; Achilonu, Ikechukwu; Dirr, Heini W.; Shonhai, Addmore
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(-)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional Partners
errMOLECULES
IF4.6
err2017-12-05
err33
errOAAI
errZininga, Tawanda; Ramatsui, Lebogang; Makhado, Pertunia Bveledzani; Makumire, Stanley; Achilinou, Ikechukwu; Hoppe, Heinrich; Dirr, Heini; Shonhai, Addmore
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The effects of mutating Tyr9 and Arg15 on the structure, stability, conformational dynamics and mechanism of GSTA3-3
errBIOPHYSICAL CHEMISTRY
IF2.2
err2017-05-01
err4
PREAI
errRobertson, Gary J.; Stoychev, Stoyan H.; Sayed, Yasien; Achilonu, Ikechukwu; Dirr, Heini W.
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Plasmodium falciparum Hsp70-z, an Hsp110 homologue, exhibits independent chaperone activity and interacts with Hsp70-1 in a nucleotide-dependent fashion
errCELL STRESS & CHAPERONES
IF3.2
err2016-05-01
err43
errOAAI
errZininga, Tawanda; Achilonu, Ikechukwu; Hoppe, Heinrich; Prinsloo, Earl; Dirr, Heini W.; Shonhai, Addmore
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Amide hydrogen exchange in HIV-1 subtype B and C proteases - insights into reduced drug susceptibility and dimer stability
errFEBS JOURNAL
IF4.2
err2014-11-04
err8
errOAAI
errNaicker, Previn; Stoychev, Stoyan; Dirr, Heini W.; Sayed, Yasien
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The Isomerization of Δ5-Androstene-3,17-dione by the Human Glutathione Transferase A3-3 Proceeds via a Conjugated Heteroannular Diene Intermediate
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2014-11-01
err4
errOAAI
errDaka, Jonathan L.; Achilonu, Ikechukwu; Dirr, Heini W.
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Polymorphic Diversity: N-Phenylbenzamide as a Possible Polymorphophore
errCRYSTAL GROWTH & DESIGN
IF3.4
err2013-07-18
err15
PREAI
errZipp, Caitlin F.; Dirr, Heini W.; Fernandes, Manuel A.; Marques, Helder M.; Michael, Joseph P.
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S-Nitrosation of Glutathione Transferase P1-1 Is Controlled by the Conformation of a Dynamic Active Site Helix
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2013-05-01
err13
errOAAI
errBalchin, David; Wallace, Louise; Dirr, Heini W.
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Energetics of ligand binding to human glutathione transferase A1-1: Tyr-9 associated localisation of the C-terminal helix is ligand-dependent
errBIOPHYSICAL CHEMISTRY
IF2.2
err2011-07-01
err3
PREAI
errBalchin, David; Dirr, Heini W.; Sayed, Yasien
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errSave
Arginine 15 stabilizes an SNAr reaction transition state and the binding of anionic ligands at the active site of human glutathione transferase A1-1
errBIOPHYSICAL CHEMISTRY
IF2.2
err2010-02-01
err21
PREAI
errGildenhuys, Samantha; Dobreva, Marina; Kinsley, Nichole; Sayed, Yasien; Burke, Jonathan; Pelly, Stephen; Gordon, Graeme P.; Sayed, Muhammed; Sewell, Trevor; Dirr, Heini W.
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Active-Site Mutations in the South African Human Immunodeficiency Virus Type 1 Subtype C Protease Have a Significant Impact on Clinical Inhibitor Binding: Kinetic and Thermodynamic Study
errJOURNAL OF VIROLOGY
IF3.8
err2008-11-15
err37
errOAAI
errMosebi, Salerwe; Morris, Lynn; Dirr, Heini W.; Sayed, Yasien
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Characterization of the binding of 8-anilinonaphthalene sulfonate to rat class Mu GST M1-1
errBIOPHYSICAL CHEMISTRY
IF2.2
err2008-10-01
err15
errOAAI
errKinsley, Nichole; Sayed, Yasien; Mosebi, Salerwe; Armstrong, Richard N.; Dirr, Heini W.
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The intersubunit lock-and-key motif in human glutathione transferase A1-1:: role of the key residues Met51 and Phe52 in function and dimer stability
errBIOCHEMICAL JOURNAL
IF4.3
err2005-12-23
err21
errOAAI
errAlves, CS; Kuhnert, DC; Sayed, Y; Dirr, HW
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A conserved N-capping motif contributes significantly to the stabilization and dynamics of the C-terminal region of class alpha glutathione S-transferases
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2005-05-01
err24
errOAAI
errDirr, HW; Little, T; Kuhnert, DC; Sayed, Y
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errSave
Characterization of bromosulphophthalein binding to human glutathione S-transferase A1-1: thermodynamics and inhibition kinetics
errBIOCHEMICAL JOURNAL
IF4.3
err2004-08-24
err32
errOAAI
errKolobe, D; Sayed, Y; Dirr, HW
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The role of an evolutionarily conserved cis-proline in the thioredoxin-like domain of human class Alpha glutathione transferase A1-1
errBIOCHEMICAL JOURNAL
IF4.3
err2003-05-15
err30
errOAAI
errNathaniel, C; Wallace, LA; Burke, J; Dirr, HW
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Research Directions

No research directions
Co-authors
Cooperation Journals
S
Salim S. Abdool Karim
H-index: 97 · Papers: 736
L
Lawrence Shapiro
H-index: 92 · Papers: 405
L
Lynn Morris
H-index: 86 · Papers: 455
M
M. Anthony Moody
H-index: 73 · Papers: 434
G
Guido Ferrari
H-index: 70 · Papers: 502
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