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Anti-human TLR7 antibody for therapeutic intervention in systemic lupus erythematosus Fukui, Ryutaro; Murakami, Yusuke; Kanno, Atsuo; Motoi, Yuji; Manno, Atsushi; Honda, Tomohiro; Yamada, Shinnosuke; Ishiguro, Jun; Kagari, Takashi; Nakamura, Kensuke; Kadokura, Michinori; Isobe, Takashi; Tomimori, Yoshiaki; Tanaka, Jun; Senaldi, Giorgio; Shimizu, Toshiyuki; Miyake, Kensuke Share Save
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Targeting toll-like receptor 7 as a therapeutic development strategy for systemic lupus erythematosus Wang, Meng; Chen, Hekai; Zhang, Tuan; Zhang, Zhikuan; Xiang, Xuwen; Gao, Meng; Guo, Yilan; Jiang, Shuangshuang; Yin, Kejun; Chen, Mintao; Huang, Jian; Zhong, Xincheng; Ohto, Umeharu; Li, Jing; Shimizu, Toshiyuki; Yin, Hang Share Save
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Structural basis of hepatitis B virus receptor binding Asami, Jinta; Park, Jae-Hyun; Nomura, Yayoi; Kobayashi, Chisa; Mifune, Junki; Ishimoto, Naito; Uemura, Tomoko; Liu, Kehong; Sato, Yumi; Zhang, Zhikuan; Muramatsu, Masamichi; Wakita, Takaji; Drew, David; Iwata, So; Shimizu, Toshiyuki; Watashi, Koichi; Park, Sam-Yong; Nomura, Norimichi; Ohto, Umeharu Share Save
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Discovery of a cystathionine γ-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5′-phosphate (PLP) via Schiff base formation Echizen, Honami; Hanaoka, Kenjiro; Shimamoto, Kazuhito; Hibi, Ryota; Toma-Fukai, Sachiko; Ohno, Hisashi; Sasaki, Eita; Komatsu, Toru; Ueno, Tasuku; Tsuchiya, Yukihiro; Watanabe, Yasuo; Otsuka, Takao; Saito, Hiroaki; Nagatoishi, Satoru; Tsumoto, Kouhei; Kojima, Hirotatsu; Okabe, Takayoshi; Shimizu, Toshiyuki; Urano, Yasuteru Share Save
TLR7/8 stress response drives histiocytosis in SLC29A3 disorders Shibata, Takuma; Sato, Ryota; Taoka, Masato; Saitoh, Shin-Ichiroh; Komine, Mayumi; Yamaguchi, Kiyoshi; Goyama, Susumu; Motoi, Yuji; Kitaura, Jiro; Izawa, Kumi; Yamauchi, Yoshio; Tsukamoto, Yumiko; Ichinohe, Takeshi; Fujita, Etsuko; Hiranuma, Ryosuke; Fukui, Ryutaro; Furukawa, Yoichi; Kitamura, Toshio; Takai, Toshiyuki; Tojo, Arinobu; Ohtsuki, Mamitaro; Ohto, Umeharu; Shimizu, Toshiyuki; Ozawa, Manabu; Yoshida, Nobuaki; Isobe, Toshiaki; Latz, Eicke; Mukai, Kojiro; Taguchi, Tomohiko; Hemmi, Hiroaki; Akira, Shizuo; Miyake, Kensuke Share Save
TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction Sakaniwa, Kentaro; Fujimura, Akiko; Shibata, Takuma; Shigematsu, Hideki; Ekimoto, Toru; Yamamoto, Masaki; Ikeguchi, Mitsunori; Miyake, Kensuke; Ohto, Umeharu; Shimizu, Toshiyuki Share Save
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Structure of SARS-CoV-2 membrane protein essential for virus assembly Zhang, Zhikuan; Nomura, Norimichi; Muramoto, Yukiko; Ekimoto, Toru; Uemura, Tomoko; Liu, Kehong; Yui, Moeko; Kono, Nozomu; Aoki, Junken; Ikeguchi, Mitsunori; Noda, Takeshi; Iwata, So; Ohto, Umeharu; Shimizu, Toshiyuki Share Save
Discovery of a lectin domain that regulates enzyme activity in mouse N-acetylglucosaminyltransferase-IVa (MGAT4A) Nagae, Masamichi; Hirata, Tetsuya; Tateno, Hiroaki; Mishra, Sushil K.; Manabe, Noriyoshi; Osada, Naoko; Tokoro, Yuko; Yamaguchi, Yoshiki; Doerksen, Robert J.; Shimizu, Toshiyuki; Kizuka, Yasuhiko Share Save
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