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Guy A. Rutter

imperial college london

94H-index
666Paper Count
3.0WCitation Count
Published Papers 332
Publication Date
Targeting ZIP12-mediated Zn2+ signaling as a treatment for pulmonary hypertension
err2026-10-21
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PREAI
errLan Zhao; Stephanie Hopley; Chien-Nien Chen; Iyobel Kibreab; Chongyang Xie; Nicoleta Baxan; Ali Ashek; Lin Zhao; Adam Fellows; Daria S. Kostyunina; Eduardo Oliver; Lei Wang; Shu Ning; Guy Rutter; Julia Gorelik; Rachel Gurrell; Richard Butt; Paul Hamblin; Martin R. Wilkins
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Pancreatic α-cells integrate immune and neuronal stimuli for insulin secretion
err2026-06-01
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PREAI
errTrimigliozzi, Kelly A.; Wiedemann, Sophia J.; Ostinelli, Giada; Rachid, Leila; Mereau, Helene; Boni-Schnetzler, Marianne; Rutter, Guy A.; Meier, Daniel T.; Donath, Marc Y.
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Pancreatic islet cell calcium ion imaging at single-cell resolution: functional identification of first-responder; highly connected (“hub”); and leader beta-cells
err2026-04-17
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errOAAI
errLF Luis Fernando Delgadillo-Silva; GO Giada Ostinelli; AP Audrey Provencher-Girard; SS Shadai Salazar; RM Rana Melhem; GA Guy A. Rutter
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Stephen Ashcroft, 27 January 1942–28 November 2025
err2026-02-21
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PREAI
errFrances Ashcroft; Richard M. Denton; Patrik Rorsman; Guy A. Rutter
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In vivo functional profiling and structural characterization of the human GLP1R A316T variant
err2026-02-04
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errOAAI
errLiliane El Eid; Yusman Manchanda; Gregory Austin; Kieran Deane-Alder; Roxana-Maria Rujan; Zamara Mariam; Affiong I. Oqua; Matthew J. Belousoff; Jorge Bernardino de la Serna; Kyle W. Sloop; Guy A. Rutter; Alex Montoya; Dominic J. Withers; Steven J. Millership; Karim Bouzakri; Ben Jones; Christopher A. Reynolds; Patrick M. Sexton; Denise Wootten; Giuseppe Deganutti; Alejandra Tomas
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ER calcium stores contribute to glucose-induced Ca2+ waves and intercellular connectivity in mouse pancreatic islets
err2025-12-10
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errOAAI
errLuis Fernando Delgadillo-Silva; Karen Dakessian; Audrey Provencher-Girard; William E. Louch; Guy A. Rutter
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A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: repurposing drugs to identify novel disruptors of 14-3-3 proteins
err2025-11-10
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errOAAI
errSiyi He; Daniel Meister; Samra Khan; Azam Mohammadzadeh; Luis Delgadillo Silva; Guy A. Rutter; John F. Trant; Gareth E. Lim
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I-BET151 modulates glucokinase gene expression and beta cell function in part through changes in FOXO1 expression
err2025-09-26
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errOAAI
errQing Wei Calvin Ho; James A. Miller; Divya Gunaseelan; Rosi Chelliah; Hemapriya Jayaranga Babu; Xin Yan Chew; Surabhi Devaraj; Vanessa Shiyun Tay; Dewei Kong; Xiaoling Wang; Daphne Yuanling Tan; Guy A. Rutter; Bernett Lee; Adrian Kee Keong Teo; Yusuf Ali
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Binding kinetics, bias, receptor internalization and effects on insulin secretion in vitro and in vivo of a novel GLP-1R/GIPR dual agonist, HISHS-2001
err2025-08-20
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errOAAI
errYusman Manchanda MSc; Ben Jones PhD; Gaelle Carrat PhD; Zenouska Ramchunder PhD; Piero Marchetti PhD; Isabelle Leclerc PhD; Rajamannar Thennati PhD; Vinod Burade PhD; Muthukumaran Natarajan MSc; Pradeep Shahi PhD; Alejandra Tomas PhD; Guy A. Rutter PhD
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LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes
err2025-07-21
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errOAAI
errJin Li; Yamei Deng; Marie Gasser; Jie Zhu; Emily M. Walker; Vaibhav Sidarala; Emma C. Reck; Dre L. Hubers; Mabelle B. Pasmooij; Chun-Shik Shin; Khushdeep Bandesh; Eftyhmios Motakis; Siddhi Nargund; Romy Kursawe; Venkatesha Basrur; Alexey I. Nesvizhskii; Michael L. Stitzel; David C. Chan; Guy A. Rutter; Scott A. Soleimanpour
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Effects of SGLT2 ablation or inhibition on corticosterone secretion in high-fat-fed mice: exploring a nexus with cytokine levels
err2025-06-20
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errOAAI
errNiki F. Brisnovali; Isabelle Franco; Amira Abdelgawwad; Hio Lam Phoebe Tsou; Thong Huy Cao; John McDonald; Antonio Riva; Guy A. Rutter; Elina Akalestou
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Exploring pancreatic beta-cell subgroups and their connectivity (Aug, 10.1038/s42255-024-01097-6, 2024)
err2024-10-23
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PREAI
errRutter, Guy A.; Gresch, Anne; Silva, Luis Delgadillo; Benninger, Richard K. P.
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Exercise activates AMPK in mouse and human pancreatic islets to decrease senescence
err2024-09-24
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PREAI
errCarapeto, Priscila; Iwasaki, Kanako; Hela, Francesko; Kahng, Jiho; Alves-Wagner, Ana B.; Middelbeek, Roeland J. W.; Hirshman, Michael F.; Rutter, Guy A.; Goodyear, Laurie J.; Aguayo-Mazzucato, Cristina
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Liver kinase B1 (LKB1) regulates the epigenetic landscape of mouse pancreatic beta cells
err2024-08-14
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errOAAI
errHaberman, Nejc; Cheung, Rebecca; Pizza, Grazia; Cvetesic, Nevena; Nagy, Dorka; Maude, Hannah; Blazquez, Lorea; Lenhard, Boris; Cebola, Ines; Rutter, Guy A.; Martinez-Sanchez, Aida
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Exploring pancreatic beta-cell subgroups and their connectivity
err2024-08-08
err1
PREAI
errRutter, Guy A.; Gresch, Anne; Delgadillo Silva, Luis; Benninger, Richard K. P.
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Engineered mini-G proteins block the internalization of cognate GPCRs and disrupt downstream intracellular signaling
err2024-07-02
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PREAI
errManchanda, Yusman; Eleid, Liliane; Oqua, Affiong I.; Ramchunder, Zenouska; Choi, Jiyoon; Shchepinova, Maria M.; Rutter, Guy A.; Inoue, Asuka; Tate, Edward W.; Jones, Ben; Tomas, Alejandra
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Intra-islet glucagon signalling regulates beta-cell connectivity, first-phase insulin secretion and glucose homoeostasis
err2024-07-01
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errOAAI
errSuba, K.; Patel, Y.; Martin-Alonso, A.; Hansen, B.; Xu, X.; Roberts, A.; Norton, M.; Chung, P.; Shrewsbury, J.; Kwok, R.; Kalogianni, V; Chen, S.; Liu, X.; Kalyviotis, K.; Rutter, G. A.; Jones, B.; Minnion, J.; Owen, B. M.; Pantazis, P.; Distaso, W.; Drucker, D. J.; Tan, T. M.; Bloom, S. R.; Murphy, K. G.; Salem, V.
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Optogenetic β cell interrogation in vivo reveals a functional hierarchy directing the Ca2+ response to glucose supported by vitamin B6
err2024-06-28
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errOAAI
errDelgadillo-Silva, Luis Fernando; Tasoez, Emirhan; Singh, Sumeet Pal; Chawla, Prateek; Georgiadou, Eleni; Gompf, Anne; Rutter, Guy A.; Ninov, Nikolay
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Multiple genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic β-cell survival and function
err2024-04-25
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errOAAI
errHu, Ming; Kim, Innah; Moran, Ignasi; Peng, Weicong; Sun, Orien; Bonnefond, Amelie; Khamis, Amna; Bonas-Guarch, Silvia; Froguel, Philippe; Rutter, Guy A.
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