Paul Modrich - Publications, H-index & Citations

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Paul Modrich

Duke University

93H-index

208Paper Count

2.9WCitation Count

Published Papers 74

Publication Date

Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

193

OAAI

Mu, D; Tursun, M; Duckett, DR; Drummond, JT; Modrich, P; Sancar, A

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A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

124

OAAI

Nicolaides, NC; Littman, SJ; Modrich, P; Kinzler, KW; Vogelstein, B

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Human MutLγ, the MLH1-MLH3 heterodimer, is an endonuclease that promotes DNA expansion

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-02-03

OAAI

Kadyrova, Lyudmila Y.; Gujar, Vaibhavi; Burdett, Vickers; Modrich, Paul L.; Kadyrov, Farid A.

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The mutagen and carcinogen cadmium is a high-affinity inhibitor of the zinc-dependent MutLα endonuclease

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-06-25

OAAI

Sherrer, Shanen M.; Penland, Elisabeth; Modrich, Paul

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Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLa activation and function in mismatch repair

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-04-24

OAAI

Genschel, Jochen; Kadyrova, Lyudmila Y.; Iyer, Ravi R.; Dahal, Basanta K.; Kadyrov, Farid A.; Modrich, Paul

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The C-terminal 20 Amino Acids of Drosophila Topoisomerase 2 Are Required for Binding to a BRCA1 C Terminus (BRCT) Domain-containing Protein, Mus101, and Fidelity of DNA Segregation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-06-01

OAAI

Chen, Yu-tsung Shane; Wu, Jianhong; Modrich, Paul; Hsieh, Tao-shih

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Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture)

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2016-05-20

OAAI

Modrich, Paul

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MutL traps MutS at a DNA mismatch

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-08-17

OAAI

Qiu, Ruoyi; Sakato, Miho; Sacho, Elizabeth J.; Wilkins, Hunter; Zhang, Xingdong; Modrichd, Paul; Hingorani, Manju M.; Erie, Dorothy A.; Weninger, Keith R.

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Hydrolytic function of Exo1 in mammalian mismatch repair

NUCLEIC ACIDS RESEARCH

IF13.1

2014-05-14

OAAI

Shao, Hongbing; Baitinger, Celia; Soderblom, Erik J.; Burdett, Vickers; Modrich, Paul

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Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System*

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-02-01

OAAI

Lindsey-Boltz, Laura A.; Kemp, Michael G.; Reardon, Joyce T.; Derocco, Vanessa; Iyer, Ravi R.; Modrich, Paul; Sancar, Aziz

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Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-07-09

OAAI

Pluciennik, Anna; Burdett, Vickers; Baitinger, Celia; Iyer, Ravi R.; Shi, Kevin; Modrich, Paul

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Christian Raetz: Scientist and Friend Extraordinaire

ANNUAL REVIEW OF BIOCHEMISTRY

IF0

2013-06-02

OAAI

Dowhan, William; Nikaido, Hiroshi; Stubbe, JoAnne; Kozarich, John W.; Wickner, William T.; Russell, David W.; Garrett, Teresa A.; Brozek, Kathryn; Modrich, Paul

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PARP-1 enhances the mismatch-dependence of 5'-directed excision in human mismatch repair in vitro

DNA REPAIR

IF2.7

2011-11-01

OAAI

Liu, Yiyong; Kadyrov, Farid A.; Modrich, Paul

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PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2010-08-16

266

OAAI

Pluciennik, Anna; Dzantiev, Leonid; Iyer, Ravi R.; Constantin, Nicoleta; Kadyrov, Farid A.; Modrich, Paul

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PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2010-07-12

OAAI

van Oers, Johanna M. M.; Roa, Sergio; Werling, Uwe; Liu, Yiyong; Genschel, Jochen; Hou, Harry, Jr.; Sellers, Rani S.; Modrich, Paul; Scharff, Matthew D.; Edelmann, Winfried

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Structure of the Endonuclease Domain of MutL: Unlicensed to Cut

MOLECULAR CELL

IF16.6

2010-07-01

122

OAAI

Pillon, Monica C.; Lorenowicz, Jessica J.; Uckelmann, Michael; Klocko, Andrew D.; Mitchell, Ryan R.; Chung, Yu Seon; Modrich, Paul; Walker, Graham C.; Simmons, Lyle A.; Friedhoff, Peter; Guarne, Alba

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MutLα and Proliferating Cell Nuclear Antigen Share Binding Sites on MutSβ

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-04-01

OAAI

Iyer, Ravi R.; Pluciennik, Anna; Genschel, Jochen; Tsai, Miaw-Sheue; Beese, Lorena S.; Modrich, Paul

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Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-02-01