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Development, validation, and usage of metrics to evaluate the quality of clinical research hypotheses Jing, Xia; Zhou, Yuchun; Cimino, James J.; Shubrook, Jay H.; Patel, Vimla L.; De Lacalle, Sonsoles; Weaver, Aneesa; Liu, Chang Share Save
Single- versus Multi-Ancestry Polygenic Risk Scores for CKD in Black Americans Jones, Alana C.; Patki, Amit; Srinivasasainagendra, Vinodh; Tiwari, Hemant K.; Armstrong, Nicole D.; Chaudhary, Ninad S.; Limdi, Nita A.; Hidalgo, Bertha A.; Davis, Brittney; Cimino, James J.; Khan, Atlas; Kiryluk, Krzysztof; Lange, Leslie A.; Lange, Ethan M.; Arnett, Donna K.; Young, Bessie A.; Diamantidis, Clarissa J.; Franceschini, Nora; Wassertheil-Smoller, Sylvia; Rich, Stephen S.; Rotter, Jerome I.; Mychaleckyj, Josyf C.; Kramer, Holly J.; Chen, Yii-Der I.; Psaty, Bruce M.; Brody, Jennifer A.; de Boer, Ian H.; Bansal, Nisha; Bis, Joshua C.; Irvin, Marguerite R. Share Save
Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations Lennon, Niall J.; Kottyan, Leah C.; Kachulis, Christopher; Abul-Husn, Noura S.; Arias, Josh; Belbin, Gillian; Below, Jennifer E.; Berndt, Sonja I.; Chung, Wendy K.; Cimino, James J.; Clayton, Ellen Wright; Connolly, John J.; Crosslin, David R.; Dikilitas, Ozan; Edwards, Digna R. Velez; Feng, Qiping; Fisher, Marissa; Freimuth, Robert R.; Ge, Tian; Berndt, Sonja; Hirschhorn, Joel; Loos, Ruth; Glessner, Joseph T.; Gordon, Adam S.; Patterson, Candace; Hakonarson, Hakon; Harden, Maegan; Harr, Margaret; Hirschhorn, Joel N.; Hoggart, Clive; Hsu, Li; Irvin, Marguerite R.; Jarvik, Gail P.; Karlson, Elizabeth W.; Khan, Atlas; Khera, Amit; Kiryluk, Krzysztof; Kullo, Iftikhar; Larkin, Katie; Limdi, Nita; Linder, Jodell E.; Loos, Ruth J. F.; Luo, Yuan; Malolepsza, Edyta; Manolio, Teri A.; Martin, Lisa J.; Mccarthy, Li; Mcnally, Elizabeth M.; Meigs, James B.; Mersha, Tesfaye B.; Mosley, Jonathan D.; Musick, Anjene; Namjou, Bahram; Pai, Nihal; Pesce, Lorenzo L.; Peters, Ulrike; Peterson, Josh F.; Prows, Cynthia A.; Puckelwartz, Megan J.; Rehm, Heidi L.; Roden, Dan M.; Rosenthal, Elisabeth A.; Rowley, Robb; Sawicki, Konrad Teodor; Schaid, Daniel J.; Smit, Roelof A. J.; Smith, Johanna L.; Smoller, Jordan W.; Thomas, Minta; Tiwari, Hemant; Toledo, Diana M.; Vaitinadin, Nataraja Sarma; Veenstra, David; Walunas, Theresa L.; Wang, Zhe; Wei, Wei-Qi; Weng, Chunhua; Wiesner, Georgia L.; Yin, Xianyong; Kenny, Eimear E. Share Save
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Potential pitfalls in the use of real-world data for studying long COVID Zhang, Harrison G.; Honerlaw, Jacqueline P.; Maripuri, Monika; Samayamuthu, Malarkodi Jebathilagam; Beaulieu-Jones, Brendin R.; Baig, Huma S.; L'Yi, Sehi; Ho, Yuk-Lam; Morris, Michele; Panickan, Vidul Ayakulangara; Wang, Xuan; Weber, Griffin M.; Liao, Katherine P.; Visweswaran, Shyam; Tan, Bryce W. Q.; Yuan, William; Gehlenborg, Nils; Muralidhar, Sumitra; Ramoni, Rachel B.; Kohane, Isaac S.; Xia, Zongqi; Cho, Kelly; Cai, Tianxi; Brat, Gabriel A.; Aaron, James R.; Agapito, Giuseppe; Albayrak, Adem; Albi, Giuseppe; Alessiani, Mario; Alloni, Anna; Amendola, Danilo F.; Angoulvant, Francois; Anthony, Li L. L. J.; Aronow, Bruce J.; Ashraf, Fatima; Atz, Andrew; Avillach, Paul; Azevedo, Paula S.; Balshi, James; Beaulieu-Jones, Brett K.; Bell, Douglas S.; Bellasi, Antonio; Bellazzi, Riccardo; Benoit, Vincent; Beraghi, Michele; Bernal-Sobrino, Jose Luis; Bernaux, Melodie; Bey, Romain; Bhatnagar, Surbhi; Blanco-Martinez, Alvar; Bonzel, Clara-Lea; Booth, John; Bosari, Silvano; Bourgeois, Florence T.; Bradford, Robert L.; Brat, Gabriel A.; Breant, Stephane; Brown, Nicholas W.; Bruno, Raffaele; Bryant, William A.; Bucalo, Mauro; Bucholz, Emily; Burgun, Anita; Cai, Tianxi; Cannataro, Mario; Carmona, Aldo; Caucheteux, Charlotte; Champ, Julien; Chen, Jin; Chen, Krista Y.; Chiovato, Luca; Chiudinelli, Lorenzo; Cho, Kelly; Cimino, James J.; Colicchio, Tiago K.; Cormont, Sylvie; Cossin, Sebastien; Craig, Jean B.; Luis Cruz-Bermudez, Juan; Cruz-Rojo, Jaime; Dagliati, Arianna; Daniar, Mohamad; Daniel, Christel; Das, Priyam; Devkota, Batsal; Dionne, Audrey; Duan, Rui; Dubiel, Julien; DuVall, Scott L.; Esteve, Loic; Estiri, Hossein; Fan, Shirley; Follett, Robert W.; Ganslandt, Thomas; Garcia-Barrio, Noelia; Garmire, Lana X.; Gehlenborg, Nils; Getzen, Emily J.; Geva, Alon; Gradinger, Tobias; Gramfort, Alexandre; Griffier, Romain; Griffon, Nicolas; Grisel, Olivier; Gutierrez-Sacristan, Alba; Han, Larry; Hanauer, David A.; Haverkamp, Christian; Hazard, Derek Y.; He, Bing; Henderson, Darren W.; Hilka, Martin; Ho, Yuk-Lam; Holmes, John H.; Hong, Chuan; Huling, Kenneth M.; Hutch, Meghan R.; Issitt, Richard W.; Jannot, Anne Sophie; Jouhet, Vianney; Kavuluru, Ramakanth; Keller, Mark S.; Kennedy, Chris J.; Key, Daniel A.; Kirchoff, Katie; Klann, Jeffrey G.; Kohane, Isaac S.; Krantz, Ian D.; Kraska, Detlef; Krishnamurthy, Ashok K.; L'Yi, Sehi; Le, Trang T.; Leblanc, Judith; Lemaitre, Guillaume; Lenert, Leslie; Leprovost, Damien; Liu, Molei; Loh, Ne Hooi Will; Long, Qi; Lozano-Zahonero, Sara; Luo, Yuan; Lynch, Kristine E.; Mahmood, Sadiqa; Maidlow, Sarah E.; Makoudjou, Adeline; Malovini, Alberto; Mandl, Kenneth D.; Mao, Chengsheng; Maram, Anupama; Martel, Patricia; Martins, Marcelo R.; Marwaha, Jayson S.; Masino, Aaron J.; Mazzitelli, Maria; Mensch, Arthur; Milano, Marianna; Minicucci, Marcos F.; Moal, Bertrand; Ahooyi, Taha Mohseni; Moore, Jason H.; Moraleda, Cinta; Morris, Jeffrey S.; Morris, Michele; Moshal, Karyn L.; Mousavi, Sajad; Mowery, Danielle L.; Murad, Douglas A.; Murphy, Shawn N.; Naughton, Thomas P.; Breda Neto, Carlos Tadeu; Neuraz, Antoine; Newburger, Jane; Ngiam, Kee Yuan; Njoroge, Wanjiku F. M.; Norman, James B.; Obeid, Jihad; Okoshi, Marina P.; Olson, Karen L.; Omenn, Gilbert S.; Orlova, Nina; Ostasiewski, Brian D.; Palmer, Nathan P.; Paris, Nicolas; Patel, Lav P.; Pedrera-Jimenez, Miguel; Pfaff, Emily R.; Pfaff, Ashley C.; Pillion, Danielle; Pizzimenti, Sara; Prokosch, Hans U.; Prudente, Robson A.; Prunotto, Andrea; Quiros-Gonzalez, Victor; Ramoni, Rachel B.; Raskin, Maryna; Rieg, Siegbert; Roig-Dominguez, Gustavo; Rojo, Pablo; Rubio-Mayo, Paula; Sacchi, Paolo; Saez, Carlos; Salamanca, Elisa; Samayamuthu, Malarkodi Jebathilagam; Sanchez-Pinto, L. Nelson; Sandrin, Arnaud; Santhanam, Nandhini; Santos, Janaina C. C.; Vidorreta, Fernando J. Sanz; Savino, Maria; Schriver, Emily R.; Schubert, Petra; Schuettler, Juergen; Scudeller, Luigia; Sebire, Neil J.; Serrano-Balazote, Pablo; Serre, Patricia; Serret-Larmande, Arnaud; Shah, Mohsin; Abad, Zahra Shakeri Hossein; Silvio, Domenick; Sliz, Piotr; Son, Jiyeon; Sonday, Charles; South, Andrew M.; Spiridou, Anastasia; Strasser, Zachary H.; Tan, Amelia L. M.; Tan, Bryce W. Q.; Tan, Byorn W. L.; Tanni, Suzana E.; Taylor, Deanne M.; Terriza-Torres, Ana I.; Tibollo, Valentina; Tippmann, Patric; Toh, Emma M. S.; Torti, Carlo; Trecarichi, Enrico M.; Tseng, Yi-Ju; Vallejos, Andrew K.; Varoquaux, Gael; Vella, Margaret E.; Verdy, Guillaume; Vie, Jill-Jenn; Visweswaran, Shyam; Vitacca, Michele; Wagholikar, Kavishwar B.; Waitman, Lemuel R.; Wang, Xuan; Wassermann, Demian; Weber, Griffin M.; Wolkewitz, Martin; Wong, Scott; Xia, Zongqi; Xiong, Xin; Ye, Ye; Yehya, Nadir; Yuan, William; Zambelli, Alberto; Zhang, Harrison G.; Zoller, Daniela; Zuccaro, Valentina; Zucco, Chiara Share Save
Returning integrated genomic risk and clinical recommendations: The eMERGE study Linder, Jodell E.; Allworth, Aimee; Bland, Harris T.; Caraballo, Pedro J.; Chisholm, Rex L.; Clayton, Ellen Wright; Crosslin, David R.; Dikilitas, Ozan; DiVietro, Alanna; Esplin, Edward D.; Forman, Sophie; Freimuth, Robert R.; Gordon, Adam S.; Green, Richard; Harden, Maegan, V; Holm, Ingrid A.; Jarvik, Gail P.; Karlson, Elizabeth W.; Labrecque, Sofia; Lennon, Niall J.; Limdi, Nita A.; Mittendorf, Kathleen F.; Murphy, Shawn N.; Orlando, Lori; Prows, Cynthia A.; Rasmussen, Luke, V; Rasmussen-Torvik, Laura; Rowley, Robb; Sawicki, Konrad Teodor; Schmidlen, Tara; Terek, Shannon; Veenstra, David; Edwards, Digna R. Velez; Absher, Devin; Abul-Husn, Noura S.; Alsip, Jorge; Bangash, Hana; Beasley, Mark; Below, Jennifer E.; Berner, Eta S.; Booth, James; Chung, Wendy K.; Cimino, James J.; Connolly, John; Davis, Patrick; Devine, Beth; Fullerton, Stephanie M.; Guiducci, Candace; Habrat, Melissa L.; Hain, Heather; Hakonarson, Hakon; Harr, Margaret; Haverfield, Eden; Hernandez, Valentina; Hoell, Christin; Horike-Pyne, Martha; Hripcsak, George; Irvin, Marguerite R.; Kachulis, Christopher; Karavite, Dean; Kenny, Eimear E.; Khan, Atlas; Kiryluk, Krzysztof; Korf, Bruce; Kottyan, Leah; Kullo, Iftikhar J.; Larkin, Katie; Liu, Cong; Malolepsza, Edyta; Manolio, Teri A.; May, Thomas; McNally, Elizabeth M.; Mentch, Frank; Miller, Alexandra; Mooney, Sean D.; Murali, Priyanka; Mutai, Brenda; Muthu, Naveen; Namjou, Bahram; Perez, Emma F.; Puckelwartz, Megan J.; Rakhra-Burris, Tejinder; Roden, Dan M.; Rosenthal, Elisabeth A.; Saadatagah, Seyedmohammad; Sabatello, Maya; Schaid, Dan J.; Schultz, Baergen; Seabolt, Lynn; Shaibi, Gabriel Q.; Sharp, Richard R.; Shirts, Brian; Smith, Maureen E.; Smoller, Jordan W.; Sterling, Rene; Suckiel, Sabrina A.; Thayer, Jeritt; Tiwari, Hemant K.; Trinidad, Susan B.; Walunas, Theresa; Wei, Wei-Qi; Wells, Quinn S.; Weng, Chunhua; Wiesner, Georgia L.; Wiley, Ken; Peterson, Josh F. Share Save
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A state-based approach to genomics for rare disease and population screening East, Kelly M.; Kelley, Whitley V.; Cannon, Ashley; Cochran, Meagan E.; Moss, Irene P.; May, Thomas; Nakano-Okuno, Mariko; Sodeke, Stephen O.; Edberg, Jeffrey C.; Cimino, James J.; Fouad, Mona; Curry, William A.; Hurst, Anna C. E.; Bowling, Kevin M.; Thompson, Michelle L.; Bebin, E. Martina; Johnson, Robert D.; Acemgil, Aras; Acemgil, Aras; Crossman, David K.; Finnila, Candice R.; Gray, David E.; Greve, Veronica; Hardy, Sharonda; Hiatt, Susan M.; Latner, Donald R.; Lawlor, James M. J.; Miskell, Edrika L.; Narmore, Whitney; Schach, Julie H.; Cooper, Gregory M.; Might, Matthew; Barsh, Gregory S.; Korf, Bruce R. Share Save
What Every Reader Should Know About Studies Using Electronic Health Record Data but May Be Afraid to Ask Kohane, Isaac S.; Aronow, Bruce J.; Avillach, Paul; Beaulieu-Jones, Brett K.; Bellazzi, Riccardo; Bradford, Robert L.; Brat, Gabriel A.; Cannataro, Mario; Cimino, James J.; Garcia-Barrio, Noelia; Gehlenborg, Nils; Ghassemi, Marzyeh; Gutierrez-Sacristan, Alba; Hanauer, David A.; Holmes, John H.; Hong, Chuan; Klann, Jeffrey G.; Loh, Ne Hooi Will; Luo, Yuan; Mandl, Kenneth D.; Daniar, Mohamad; Moore, Jason H.; Murphy, Shawn N.; Neuraz, Antoine; Ngiam, Kee Yuan; Omenn, Gilbert S.; Palmer, Nathan; Patel, Lav P.; Pedrera-Jimenez, Miguel; Sliz, Piotr; South, Andrew M.; Tan, Amelia Li Min; Taylor, Deanne M.; Taylor, Bradley W.; Torti, Carlo; Vallejos, Andrew K.; Wagholikar, Kavishwar B.; Weber, Griffin M.; Cai, Tianxi Share Save
Opportunity for Genotype-Guided Prescribing Among Adult Patients in 11 US Health Systems Hicks, J. Kevin; El Rouby, Nihal; Ong, Henry H.; Schildcrout, Jonathan S.; Ramsey, Laura B.; Shi, Yaping; Tang, Leigh Anne; Aquilante, Christina L.; Beitelshees, Amber L.; Blake, Kathryn V.; Cimino, James J.; Davis, Brittney H.; Empey, Philip E.; Kao, David P.; Lemkin, Daniel L.; Limdi, Nita A.; Lipori, Gloria P.; Rosenman, Marc B.; Skaar, Todd C.; Teal, Evgenia; Tuteja, Sony; Wiley, Laura K.; Williams, Helen; Winterstein, Almut G.; Van Driest, Sara L.; Cavallari, Larisa H.; Peterson, Josh F. Share Save
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Melusin: A cardioprotective chaperone able to modulate lipid metabolism and ROS production in the heart Sorge, Matteo; Gallo, Andrea; Cavallari, Eleonora; Sbroggio, Mauro; Rubinetto, Cristina; Cimino, James; Moiso, Enrico; Haute, Alexandra; Femmino, Saveria; Raimondi, Andrea; Penna, Claudia; Pagliaro, Pasquale; Ghigo, Alessandra; Hirsch, Emilio; Tacchetti, Carlo; Digilio, Giuseppe; Riganti, Chiara; Tarone, Guido; Brancaccio, Mara Share Save
International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium Brat, Gabriel A.; Weber, Griffin M.; Gehlenborg, Nils; Avillach, Paul; Palmer, Nathan P.; Chiovato, Luca; Cimino, James; Waitman, Lemuel R.; Omenn, Gilbert S.; Malovini, Alberto; Moore, Jason H.; Beaulieu-Jones, Brett K.; Tibollo, Valentina; Murphy, Shawn N.; L'Yi, Sehi; Keller, Mark S.; Bellazzi, Riccardo; Hanauer, David A.; Serret-Larmande, Arnaud; Gutierrez-Sacristan, Alba; Holmes, John J.; Bell, Douglas S.; Mandl, Kenneth D.; Follett, Robert W.; Klann, Jeffrey G.; Murad, Douglas A.; Scudeller, Luigia; Bucalo, Mauro; Kirchoff, Katie; Craig, Jean; Obeid, Jihad; Jouhet, Vianney; Griffier, Romain; Cossin, Sebastien; Moal, Bertrand; Patel, Lav P.; Bellasi, Antonio; Prokosch, Hans U.; Kraska, Detlef; Sliz, Piotr; Tan, Amelia L. M.; Ngiam, Kee Yuan; Zambelli, Alberto; Mowery, Danielle L.; Schiver, Emily; Devkota, Batsal; Bradford, Robert L.; Daniar, Mohamad; Daniel, Christel; Benoit, Vincent; Bey, Romain; Paris, Nicolas; Serre, Patricia; Orlova, Nina; Dubiel, Julien; Hilka, Martin; Jannot, Anne Sophie; Breant, Stephane; Leblanc, Judith; Griffon, Nicolas; Burgun, Anita; Bernaux, Melodie; Sandrin, Arnaud; Salamanca, Elisa; Cormont, Sylvie; Ganslandt, Thomas; Gradinger, Tobias; Champ, Julien; Boeker, Martin; Martel, Patricia; Esteve, Loic; Gramfort, Alexandre; Grisel, Olivier; Leprovost, Damien; Moreau, Thomas; Varoquaux, Gael; Vie, Jill-Jenn; Wassermann, Demian; Mensch, Arthur; Caucheteux, Charlotte; Haverkamp, Christian; Lemaitre, Guillaume; Bosari, Silvano; Krantz, Ian D.; South, Andrew; Cai, Tianxi; Kohane, Isaac S. Share Save
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