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Ralph H. Hruban

department of pathology

209H-index
2.0KPaper Count
20.4WCitation Count
Published Papers 407
Publication Date
Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system
err2026-02-22
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errMark J Arends; Irene Esposito; Anthony J Gill; Ralph H Hruban; Joseph D Khoury; Motohiro Kojima; Elizabeth A Montgomery; Fatimah Abdulkareem; Fátima Carneiro; Guido Costamagna; Gregory Lauwers; Alexandros D Polydorides; Guido Rindi; Massimo Rugge; Peter Schirmacher; Amitabh Srivastava; James Yao; Jennelle C Hodge; James G Kench; Bharat Rekhi; Miguel Reyes-Múgica; Antonia R Sepulveda; Chanjuan Shi; Pavitratha Puspanathan; Harshima Wijesinghe; Christine Giesen; Blanca Iciar Indave Ruiz; Dilani Lokuhetty; WCT standing editorial board; Iris D Nagtegaal
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Evidence that extra copies of chromosome 1q play a role in the early phases of pancreatic neoplasia
err2026-02-20
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errOAAI
errChristopher Douville; Jeeun Parksong; Marco Dal Molin; Sarah Graham; Patricia T. Greipp; Ryan Knudson; Samuel Curtis; Yuxuan Wang; Lisa Dobbyn; Maria Popoli; Janine Ptak; Natalie Silliman; Katharine Romans; Christine A. Iacobuzio-Donahue; Alvin P. Makoohon-Moore; Anne Marie Lennon; Michael Goggins; Ralph H. Hruban; Ashley Kiemen; Chetan Bettegowda; Kenneth W. Kinzler; Nickolas Papadopoulos; Laura D. Wood; Bert Vogelstein
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Follow-up of prior CT scans as part of patient care and continuous learning: A call to action
err2026-01-01
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PREAI
errFishman, Elliot K.; Smith, Connor W.; Chu, Linda C.; Hruban, Ralph H.
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PancreaSeq Genomic Classifier (PancreaSeq GC) Improves Pancreatic Cyst Classification and Detection of Advanced Neoplasia: A Multi-institutional Validation Study
err2025-12-12
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errAatur D. Singhi; Abigail I. Wald; Katelyn Smith; Lynn Wolkenstein; Robert D. Bubar; Ricardo Diaz-Aragon; Maria Grupillo; Danielle Guckin; Yi-Tak Lai; Randall E. Brand; Kevin McGrath; Walter G. Park; Patrick R. Pfau; Patricio M. Polanco; Nisa Kubiliun; John DeWitt; Jeffrey J. Easler; Aamir Dam; Shaffer R. Mok; Michael B. Wallace; Brian A. Boone; Wallis Marsh; Shyam Thakkar; Kimberly J. Fairley; Elham Afghani; Yasser Bhat; Sanjay Ramrakhiani; John Nasr; Nikhil R. Thiruvengadam; Asif Khalid; Kenneth Fasanella; Jennifer Chennat; Rohit Das; Harkirat Singh; Adam Slivka; Charles Gabbert; Tarek Sawas; Thomas Tielleman; Hendrikus Dutch Vanderveldt; Anna Tavakkoli; Lynette M. Smith; Anju H. Singhi; Sara A. Singhi; Stephanie Romutis; Sultan Mahmood; Amy E. Hosmer; Julia McNabb-Baltar; Anne Marie Lennon; Ralph H. Hruban; Nuha Shaker; Alessandro Paniccia; Amer Zureikat; Kenneth K. Lee; Melanie Ongchin; Herbert Zeh; Rebecca Minter; C. Max Schmidt; Jin He; Marina N. Nikiforova
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TP53/KRAS variant allele frequency ratio predicts advanced disease in mucin-producing cystic neoplasms of the pancreas
err2025-12-01
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PREAI
errLin, Ming-Tseh; Afghani, Elham; Canto, Marcia, I; Zhu, Jing; Ali, Syed Z.; Wood, Laura D.; He, Jin; Lafaro, Kelly J.; Hruban, Ralph H.; Eshleman, James R.
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Benchmarking robustness of automated CT pancreas segmentation: achieving human-level reliability through human-in-the-loop optimization
err2025-11-01
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errOAAI
errOviedo, Felipe; Lopez-ramirez, Felipe; Tixier, Florent; Kawamoto, Satomi; Blanco, Alejandra; Dodhia, Rahul; Hruban, Ralph H.; Weeks, William B.; Lavista Ferres, Juan M.; Fishman, Elliot K.; Chu, Linda C.
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Mild Dilatation of the Main Pancreatic Duct Is a Risk Factor for Progression to Pancreatic Cancer in High-Risk Individuals
err2025-10-01
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errOAAI
errAbou Diwan, Elizabeth; Saba, Helena; Blackford, Amanda L.; Dbouk, Mohamad; Chu, Linda; He, Jin; Burkhart, Richard; Hruban, Ralph H.; Goggins, Michael; Canto, Marcia Irene
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Clinical predictors of pancreatic fibrosis in patients with recurrent acute and chronic pancreatitis
err2025-09-19
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PREAI
errAida A. Metri; Mahya Faghih; Elizabeth Thompson; Michael Noë; Rifat Mannan; Rita Kalyani; Erika Gunzelman; Elham Afghani; Lara Cheesman; Venkata S. Akshintala; Merve Gurakar; Zahra Yousefli; Daniel Warren; Niraj M. Desai; Zhaoli Sun; Christi Walsh; Martin A. Makary; Ralph H. Hruban; Jin He; Atif Zaheer; Vikesh K. Singh
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Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct patterns and potential markers of progression
err2025-08-28
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PREAI
errYuefan Wang; Tung-Shing M. Lih; Jae W. Lee; Takao Ohtsuka; Yuto Hozaka; Mari Mino-Kenudson; Nazmi Volkan Adsay; Claudio Luchini; Aldo Scarpa; Ajay V. Maker; Grace E. Kim; Jorge Paulino; Lijun Chen; Jongmin Woo; Liyuan Jiao; Zhenyu Sun; Davina Goodman; Michael J. Pflüger; Nicholas J. Roberts; Hanno Matthaei; Michael G. Goggins; Laura D. Wood; Toru Furukawa; Hui Zhang; Ralph H. Hruban
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Recurrent BEND2 Fusion Genes Identified by Whole Transcriptome Sequencing of Non-Functional Pancreatic Neuroendocrine Tumors Correlate with Poor Patient Prognosis
err2025-08-08
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errOAAI
errMichelle A. Wood-Trageser; C. Tolson Nichols; Danielle A. Hutchings; Diana Bell; Abigail I. Wald; Katelyn Smith; Seung-Mo Hong; Claudio Luchini; Lodewijk A.A. Brosens; Anna Vera D. Verschuur; Michele Bevere; Rita T. Lawlor; Aldo Scarpa; Shannon Keating; James Tucker; Roderick J. O’Sullivan; Ta-Chiang Liu; Kevin McGrath; Kenneth Fasanella; Randall E. Brand; Anne Marie Lennon; Rohit Das; Harkirat Singh; Adam Slivka; Sultan Mahmood; Amy E. Hosmer; Asif Khalid; Stephanie L. Romutis; Amer H. Zureikat; Herbert J. Zeh; Melissa E. Hogg; Kenneth K. Lee; Alessandro Paniccia; Geoffrey Nunns; Melanie Ongchin; Walter G. Park; Patricio M. Polanco; Jin He; Diane M. Simeone; Cristina R. Ferrone; Dennis Hsu; Janie Zhang; Vikram Gorantla; John Rhee; Ralph H. Hruban; Anju H. Singhi; Sara A. Singhi; Candice K. Wang; Nuha Shaker; Robert Bubar; Maria Grupillo; Yi-Tak Lai; Marina N. Nikiforova; Christopher M. Heaphy; Kevin M. Waters; Aatur D. Singhi
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The Brescia International Multidisciplinary Consensus Guidelines on the Optimal Pathology Assessment and Multidisciplinary Pathways of Non-Pancreatic Neoplasms in and Around the Ampulla of Vater (PERIPAN)
err2025-07-29
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errMohammad Abu Hilal; Bas A. Uijterwijk; Daniël H. L. Lemmers; Boris V. Janssen; Marc G. Besselink; Denise Bianchi; Arantza Fariña; Noriyoshi Fukushima; Anthony J. Gill; Seung-Mo Hong; Alyssa Krasinskas; Claudio Luchini; Laura Melocchi; Giulio Rossi; Aldo Scarpa; Olca Basturk; Deyali Chatterjee; Angela Chou; Irene Esposito; Roger Feakins; Bas Groot Koerkamp; Ralph H. Hruban; Stefano La Rosa; Chanjuan Shi; Aatur Singhi; Joanne Verheij; Huamin Wang; Sergio Alfieri; Fabio Ausania; Adnan Alseidi; Marco J. Bruno; Ugo Boggi; Claudio Bnà; Christos Dervenis; Massimo Falconi; Michele Ghidini; Jakob W. Kist; Giovanni Marchegiani; Michele Milella; Roberto Salvia; Ajith Siriwardena; Hanneke Wilmink; Alberto Zaniboni; Shaimaa Al-Janabi; Maia Blomhoff Holm; Eva Roos; Naoki Sano; In Hye Song; Zeynep Tarcan; Gianpaolo Balzano; Isabella Frigerio; Alfredo Guglielmi; Giuseppe Malleo; Horacio Asbun; Volkan Adsay; Caroline Verbeke
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Three-dimensional assessments are necessary to determine the true, spatially resolved composition of tissues
err2025-06-09
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errOAAI
errAndré Forjaz; Eduarda Vaz; Valentina Matos Romero; Saurabh Joshi; Vasco Queiroga; Alicia M. Braxton; Ann C. Jiang; Kohei Fujikura; Toby Cornish; Seung-Mo Hong; Ralph H. Hruban; Pei-Hsun Wu; Laura D. Wood; Ashley L. Kiemen; Denis Wirtz
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Radiomics machine learning algorithm facilitates detection of small pancreatic neuroendocrine tumors on CT
err2025-01-01
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PREAI
errLopez-Ramirez, Felipe; Soleimani, Sahar; Azadi, Javad R.; Sheth, Sheila; Kawamoto, Satomi; Javed, Ammar A.; Tixier, Florent; Hruban, Ralph H.; Fishman, Elliot K.; Chu, Linda C.
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Power-law growth models explain incidences and sizes of pancreatic cancer precursor lesions and confirm spatial genomic findings
err2024-07-26
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errOAAI
errKiemen, Ashley L.; Wu, Pei-Hsun; Braxton, Alicia M.; Cornish, Toby C.; Hruban, Ralph H.; Wood, Laura D.; Wirtz, Denis; Zwicker, David
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CRISPR-Cas9 for selective targeting of somatic mutations in pancreatic cancers
err2024-06-19
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errOAAI
errTeh, Selina Shiqing K.; Bowland, Kirsten; Halper-Stromberg, Eitan; Kotwal, Akhil; Bennett, Alexis; Skaist, Alyza; Tang, Jacqueline; Cai, Fidel; Macoretta, Antonella; Liang, Hong; Kamiyama, Hirohiko; Wheelan, Sarah; Lin, Ming-Tseh; Hruban, Ralph H.; Hung, Chien-Fu; Goldstein, Michael; Scharpf, Robert B.; Roberts, Nicholas J.; Eshleman, James R.
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CRISPR-cas9 genetic targeting of metastatic pancreatic cancer
err2024-03-22
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PREAI
errBowland, Kirsten; Lai, Jiaying; Teh, Selina Shiqing K.; Bennett, Alexis; Skaist, Alyza; Zhang, Yan; Thompson, Elizabeth; Hruban, Ralph H.; Roberts, Nicholas J.; Karchin, Rachel; Iacobuzio-Donahue, Christine A.; Eshleman, James R.
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Three-dimensional immune atlas of pancreatic cancer precursor lesions reveals large inter- and intra-lesion heterogeneity
err2024-03-22
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PREAI
errKiemen, Ashley L.; Almagro-Perez, Cristina; Matos-Romero, Valentina; Braxton, Alicia M.; Mahesh-Babu, Jaanvi; Thompson, Elizabeth D.; Cornish, Toby C.; Wu, PeiHsun; Wood, Laura D.; Munoz-Barrutia, Arrate; Hruban, Ralph H.; Wirtz, Denis
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Three-dimensional multi-omic analysis of early invasion of human pancreatic ductal adenocarcinoma from IPMN
err2024-03-22
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PREAI
errDatta, Shalini; Shin, Sarah M.; Kanacharoen, Jessie; Pfluger, Michael Johannes; Hirose, Katsuya; Forjaz, Andre; Graham, Sarah; Wu, Pei-Hsun; Hruban, Ralph H.; Wirtz, Denis; Ho, Won Jin; Kiemen, Ashley L.; Wood, Laura D.
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