logo
CanyamAI summaries for academic research
language
MobileMobile
  • Phone FeatureWeChat Mini Program
EnglishEnglish
noticeNotice
BlogBlog
delete
arrow
Back
I

Irene M. Ghobrial

dana-farber cancer institute

99H-index
1.1KPaper Count
4.5WCitation Count
Published Papers 185
Publication Date
logo
Pharmacological targeting of IRF4 as a therapeutic strategy for multiple myeloma
errNature Chemical Biology
IF13.7
err2026-05-28
err0
PREAI
errMichael P. Agius; Chen Song; Qi Liu; Tomoki Iemura; Laura Hevenor; N. Connor Payne; Romanos Sklavenitis Pistofidis; Lorena Pantano; Hongfang Zhao; Hyuk-Soo Seo; Daniel Heilpern-Mallory; Caleb Heaslip; Zhen-Yu J. Sun; Puspalata Bashyal; Michelle P. Aranha; Elizabeth Lightbody; Ralph Mazitschek; Sirano Dhe-Paganon; Constantine S. Mitsiades; Irene M. Ghobrial; Jun Qi
errShare
errSave
Ciltacabtagene autoleucel in high-risk smoldering multiple myeloma: the CAR-PRISM phase 2 trial
errNature Medicine
IF50
err2026-04-20
err0
errOAAI
errOmar Nadeem; David M. Cordas dos Santos; Sarah Nikiforow; Anna Bosch-Vilaseca; Elizabeth O’Donnell; Robert Redd; Kevin C. DeBraganca; Adam S. Sperling; Yuxin Liu; Caleb McEntire; Frances Arters; Colin O’Donnell; Brendan Kineavy; Marjorie Marto; Amy Bergeron; Emilie Swenson; Kristin McHugh; Abigail Caron; Quentin Berry; Hope Wei; Emily Durlacher; Elizabeth Grimm; Francesco Corrado; Nayda Bidikian; Rocio Montes de Oca; Tamar Lengil; Denise De Wiest; Casey Gervais; Kevin Panaro; Eric L. Smith; Kenneth Anderson; Caron Jacobson; Nikhil C. Munshi; Paul Richardson; Deepu Madduri; Jordan M. Schecter; Craig Tendler; Mark A. Wildgust; Lorenzo Trippa; Maria Victoria Mateos; Jerome Ritz; Irene M. Ghobrial
errShare
errSave
Circulating Tumor Cells in Multiple Myeloma: From Peripheral Clues to Central Insights
errAmerican Journal of Hematology
IF9.9
err2026-04-13
err0
errOAAI
errBenjamin Podvin; Bruno Paiva; Irene M. Ghobrial; Salomon Manier
errShare
errSave
Daratumumab in high-risk MGUS and low-risk smoldering myeloma: results of the Phase II D-PRISM study
errNature Communications
IF15.7
err2026-04-08
err0
errOAAI
errOmar Nadeem; Michelle P. Aranha; Robert A. Redd; Michael Koontz; Jeffrey V. Matous; Andrew J. Yee; Jeffrey A. Zonder; Andrew Kin; Sophie Magidson; Elizabeth D. Lightbody; Ting Wu; Floris Chabrun; Jean-Baptiste Alberge; Ankit K. Dutta; Jacqueline Perry; Ashlee Sturtevant; Mahshid Rahmat; Junko Tsuji; Christine Davie; Caroline Ricciardi; Frances Arters; Marjorie Marto; Amy Bergeron; Jacalyn Rosenblatt; Elizabeth K. O’Donnell; Tarek H. Mouhieddine; Lorena Pantano; Jacob P. Laubach; Paul G. Richardson; Gad Getz; Lorenzo Trippa; Romanos Sklavenitis-Pistofidis; Irene M. Ghobrial
errShare
errSave
Immune biomarkers of increased infection risk in multiple myeloma
errBlood
IF23.1
err2026-04-01
err1
PREAI
errZabaleta, Aintzane; Tamariz-Amador, Luis-Esteban; V. Kostopoulos, Ioannis; Sklavenitis-Pistofidis, Romanos; Smits, Febe; Rodriguez-Otero, Paula; Roncal, Carmen; Aranha, Michelle P.; Zihala, David; Machu, Michaela; Tsakirakis, Nikolaos; Bakouros, Panagiotis; Tsitsilonis, Ourania; Solia, Irene; Moreno, Cristina; Maia, Catarina; Martin-Sanchez, Esperanza; Perez, Jose J.; Encinas, Cristina; Rios-Tamayo, Rafael; Oriol, Albert; Blanchard, Maria-Jesus; de Arriba, Felipe; Gonzalez, Maria-Esther; Lakhwani, Sunil; Sureda, Anna; Caban, Valentin; Escalante, Fernando; Carrillo-Cruz, Estrella; Perez-Montan, Albert; Ocio, Enrique M.; Bargay, Joan; Orfao, Alberto; Jelinek, Tomas; Ghobrial, Irene M.; Mutis, Tuna; Zweegman, Sonja; Terpos, Evangelos; Kastritis, Efstathios; Martinez-Lopez, Joaquin; Lahuerta, Juan-Jose; de Larrea, Carlos Fernandez; Rosin, Laura; Blade, Joan; Mateos, Maria-Victoria; San-Miguel, Jesus; Cedena, Maria-Teresa; Puig, Noemi; Paiva, Bruno
errShare
errSave
Enhanced dynamic risk stratification of smoldering multiple myeloma
errNature Medicine
IF50
err2026-03-01
err1
errOAAI
errChabrun, Floris; Schwartz, Daniel E.; Gentile, Susanna; Mai, Elias K.; Gupta, Tulika R.; Perry, Jacqueline; Cordas Dos Santos, David M.; Hielscher, Thomas; Werly, Annika; Schmidt, Sophia K.; Theodorakakou, Foteini; Fotiou, Despina; Liacos, Christine Ivy; Kanellias, Nikolaos; Gisbert, Noelia Collado; Martin-Sanchez, Esperanza; Termini, Rosalinda; Waldschmidt, Johannes; Chavda, Selina J.; Ainley, Louise; Da Via, Matteo Claudio; De Magistris, Claudio; Pettine, Loredana; Timonian, Michael A.; Alberge, Jean-Baptiste; Patel, Vidhi; Costello, Patrick; Tobia, Catherine; Phan, Sally; Lamb, Jennifer; Silverio, Maria-Theresa; Davis, Maya; O'donnell, Elizabeth K.; Marinac, Catherine R.; Nadeem, Omar; Bolli, Niccolo; Yong, Kwee; Kortum, K. Martin; Einsele, Hermann; Mateos, Maria-Victoria; Kumar, Shaji; San-Miguel, Jesus F.; Paiva, Bruno; Kastritis, Efstathios; Dimopoulos, Meletios A.; Raab, Marc S.; Trippa, Lorenzo; Ghobrial, Irene M.
errShare
errSave
Performance evaluation of an automated mass spectrometry system for the measurement and isotyping of monoclonal immunoglobulins
errClinica Chimica Acta
IF2.9
err2026-02-27
err0
errOAAI
errJamie Ashby; Daniel McEntee; Dhananjay Sakrikar; Luke Ouverson; Rhiannon Stanton; Nia Marrott; Roshani R. Patel; Cristina Simion; Syreeta Allen; Manisha Bhutani; David M. Foureau; Kaleb B. McLendon; Andrew S. Neish; Habib El-Khoury; Irene M. Ghobrial; David Barnidge; Gabriella Lakos; Mark Perkins; Stephen Harding; Oscar Berlanga
errShare
errSave
Comparative performance of the EXENT® System and electrophoretic methods for the identification and quantification of M proteins in patients with monoclonal gammopathies
errCLINICAL CHEMISTRY
IF6.3
err2025-10-01
err0
errOAAI
errLakos, Gabriella; Allen, Syreeta; Malin, Gemma; Simion, Cristina; El-Khoury, Habib; Colchie, Julia; Bertamini, Luca; Fleming, Grace; Horowitz, Erica; Ghobrial, Irene; Mclendon, Kaleb; Solis, Zianya; Neish, Andrew; Grewal, Sarah; Roback, John; Wechalekar, Ashutosh; Foureau, David; Bhutani, Manisha; Iliev, Victor; Berlanga, Oscar
errShare
errSave
Diagnostic performance of the EXENT® System in monoclonal gammopathy
errCLINICAL CHEMISTRY
IF6.3
err2025-10-01
err0
errOAAI
errLakos, Gabriella; Allen, Syreeta; Malin, Gemma; Simion, Cristina; El-Khoury, Habib; Colchie, Julia; Bertamini, Luca; Fleming, Grace; Horowitz, Erica; Ghobrial, Irene; McLendon, Kaleb; Solis, Zianya; Roback, John; Neish, Andrew; Grewal, Sarah; Wechalekar, Ashutosh; Foureau, David; Bhutani, Manisha; Iliev, Victor; Berlanga, Oscar
errShare
errSave
Accurate recognition and characterization of biclonal gammopathies by mass spectrometry
errJOURNAL OF IMMUNOLOGICAL METHODS
IF1.6
err2025-10-01
err0
PREAI
errBerlanga, Oscar; Allen, Syreeta L.; Malin, Gemma M.; Simion, Cristina; El-Khoury, Habib G.; Colchie, Julia; Bertamini, Luca; Fleming, Grace; Horowitz, Erica M.; Ghobrial, Irene M.; Solis, Zianya M.; McLendon, Kaleb B.; Roback, John D.; Neish, Andrew S.; Grewal, Sarah K.; Wechelekar, Ashutosh; Foureau, David M.; Bhutani, Manisha; Voorhees, Peter M.; Lakos, Gabriella
errShare
errSave
Numbat-multiome: inferring copy number variations by combining RNA and chromatin accessibility information from single-cell data
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2025-09-01
err1
errOAAI
errLi, Ruitong; Alberge, Jean-Baptiste; Keshavarzian, Tina; Tsuji, Junko; Gustafsson, Johan; Rahmat, Mahshid; Lightbody, Elizabeth D.; Deng, Stephanie L.; Riviero, Santiago; Miller, Mendy; Naz Cemre Kalayci, F.; Wiestner, Adrian; Sun, Clare; Lupien, Mathieu; Ghobrial, Irene; Parry, Erin; Gao, Teng; Getz, Gad
errShare
errSave
SWIFT-seq enables comprehensive single-cell transcriptomic profiling of circulating tumor cells in multiple myeloma and its precursors
errNature Cancer
IF28.5
err2025-08-08
err0
PREAI
errElizabeth D. Lightbody; Romanos Sklavenitis-Pistofidis; Ting Wu; Junko Tsuji; Danielle T. Firer; Michael P. Agius; Ankit K. Dutta; Hadley Barr; Sungjae Kim; Jean-Baptiste Alberge; Sarah Nersesian; Tim Coorens; Nicholas J. Haradhvala; Nang Kham Su; Cody J. Boehner; Michelle P. Aranha; Mahshid Rahmat; Yoshinobu Konishi; Laura Hevenor; Katherine Towle; Erica Horowitz; Jacqueline Perry; Maya Davis; Kelly A. Walsh; Christian J. Cea-Curry; Grace Fleming; Michael E. Vinyard; Daniel Heilpern-Mallory; Habib El-Khoury; Annie Cowan; John E. Ready; Catherine R. Marinac; Gad Getz; Irene M. Ghobrial
errShare
errSave
Updates on mechanisms of disease progression in precursor myeloma: Monoclonal gammopathy of undermined significance and smoldering myeloma
errPRESSE MEDICALE
IF3.4
err2025-03-01
err1
PREAI
errSaade, Cynthia; Ghobrial, Irene M.
errShare
errSave
Distress and symptom burden in patients with monoclonal gammopathy of undetermined significance and smoldering myeloma
errBLOOD ADVANCES
IF7.1
err2025-02-04
err0
errOAAI
errO'Donnell, Elizabeth K.; Carroll, Jennifer E.; Perry, Jaqueline; Padgett, Katherine; Harris, Benjamin; Patel, Vidhi; Nadeem, Omar; El-Jawahri, Areej; Ghobrial, Irene M.; Marinac, Catherine R.
errShare
errSave
Correction: miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer
errMOLECULAR CANCER
IF33.9
err2025-01-31
err0
errOAAI
errCorcoran, Claire; Rani, Sweta; Breslin, Susan; Gogarty, Martina; Ghobrial, Irene M.; Crown, John
errShare
errSave
Early intervention with daratumumab improves survival for patients with high-risk smouldering myeloma
errNATURE REVIEWS CLINICAL ONCOLOGY
IF82.2
err2025-01-24
err0
PREAI
errNadeem, Omar; Ghobrial, Irene M.
errShare
errSave
Landscape Assessment of the Perceptions of Distress and Symptom Burden in Patients with Monoclonal Gammopathy of Unknown Significance (MGUS) and Smoldering Multiple Myeloma (SMM)
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errO'Donnell, Elizabeth K.; Carroll, Jennifer; Perry, Jacqueline; Padgett, Katherine; Patel, Vidhi; Nadeem, Omar; El-Jawahri, Areej; Ghobrial, Irene; Marinac, Catherine R.
errShare
errSave
Single-Cell RNA-Sequencing of 6 Million Tumor and Immune Cells in 365 Patients with MGUS and SMM Demonstrates Complex Progressive Changes in Immune Cell Functionality with a Distinct Footprint on Tumor Cell Biology and Disease Control
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errSklavenitis-Pistofidis, Romanos; Wu, Ting; Lightbody, Elizabeth D.; Konishi, Yoshinobu; Rahmat, Mahshid; Agius, Michael P.; Tsuji, Junko; Alberge, Jean-Baptiste; Timonian, Michael; Dutta, Ankit K.; Aranha, Michelle P.; Bidikian, Nayda; Barr, Hadley; Haradhvala, Nicholas J.; Sade-Feldman, Moshe; Getz, Gad; Ghobrial, Irene
errShare
errSave
Deep Learning Unveils Characteristics of Immune B Cell Aging in >17,000 Samples and Identifies Changes in the Immunoglobulin Repertoire Distribution and the Development of Monoclonal Gammopathy
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errPhdpharmd, Floris Chabrun; Alberge, Jean-Baptiste; Allam, Sabine; Perry, Jacqueline F.; El-Khoury, Habib; Lee, David J.; Timonian, Michael; Bertamini, Luca; Barr, Hadley; Fleming, Grace; Flinn, Joseph Casey; Murphy, Ciara; Wallin, Sofia; Hussain, Hiba; Lightbody, Elizabeth D.; Kim, Sungjae; Perkins, Mark C.; Harding, Stephen J.; Sakrikar, Dhananjay; Pistofidis, Romanos Sklavenitis; Anderson, Kenneth C.; Nadeem, Omar; O'Donnell, Elizabeth K.; Liu, Yuxin; Chen, Wenlong; Joffe, Maureen; Ebert, Benjamin Levine; Marinac, Catherine R.; Getz, Gad; Ghobrial, Irene
errShare
errSave
Single-Cell Profiling of ∼1.7 Million Plasma Cells across > 250 Individuals Reveals Transcriptional Signatures of Progression and Clonal Expansion in Multiple Myeloma and Its Precursor Stages
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errTsuji, Junko; Lightbody, Elizabeth D.; Sklavenitis-Pistofidis, Romanos; Wu, Ting; Agius, Michael P.; Firer, Danielle T.; Rahmat, Mahshid; Barr, Hadley; Konishi, Yoshinobu; Dutta, Ankit K.; Alberge, Jean-Baptiste; Su, Nang Kham; Boehner, Cody J.; Aranha, Michelle P.; Hevenor, Laura; Towle, Katherine; Horowitz, Erica M.; Davis, Maya; Perry, Jacqueline F.; Aguet, Francois; Li, Ruitong; Kim, Sungjae; Haradhvala, Nicholas J.; Boiarsky, Rebecca; Getz, Gad; Ghobrial, Irene
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
G
Guido Kroemer
H-index: 283 · Papers: 2.3K
G
Gad Getz
H-index: 248 · Papers: 1.8K
G
Graham A. Colditz
H-index: 247 · Papers: 2.4K
K
Kenneth C. Anderson
H-index: 199 · Papers: 3.1K
D
David L. Kaplan
H-index: 194 · Papers: 2.4K
View more