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Understanding the Chemical Characteristics of Payloads and the Expression of Tumor-Associated Antigens of ADCs in Clinical Development Nieto-Jimenez, Cristina; Paniagua-Herranz, Lucia; Bosi, Carlo; Poyatos-Racionero, Elisa; Pedregal, Manuel; Moreno, Victor; Calvo, Emiliano; Dominguez-Jurado, Elena; Hernandez, Tatiana; Perez-Segura, Pedro; Gyorffy, Balazs; Alonso-Moreno, Carlos; Bianchini, Giampaolo; Ocana, Alberto Share Save
Mapping MAGE-A4 expression in solid cancers for targeted therapies Habigt, Christin; Rottey, Sylvie; Spanggaard, Iben; Lopez, Juanita S.; Garralda, Elena; Calvo, Emiliano; Bechter, Oliver; Desai, Jayesh; Galot, Rachel; Gandhi, Leena; Heil, Florian; Rieder, Natascha; Dimitrov, Ivan; Quetglas, Iris Martinez; Heichinger, Christian; Keshelava, Nino; Roller, Andreas Share Save
A PRELIMINARY SIGNS OF CLINICAL ACTIVITY OF TUVUSERTIB (M1774), A HIGHLY POTENT ORAL ATR INHIBITOR, IN REFRACTORY IDH MUTATED GLIOMA PATIENTS WITH P53 AND ATRX MUTATIONS; A CASE SERIES FROM A FIH STUDY Vieito, M.; Moreno, I; Gomez-Puerto, D.; Ruiz, I. Victoria; Indacochea, A.; Garralda, E.; Gonzalez, S.; Calvo, E.; Juanita, L.; Szucs, Z.; Reischmann, N.; Pineda, E. Share Save
Comparison of single agent versus combination activity of enfortumab vedotin (EV) and sacituzumab govitecan (SG) in a panel of bladder cancer XPDX models Simonson, A.; Flores, J.; Mercer, G.; Lopez, M.; Garcia, R.; Lund, J.; Banos, N.; Papadopoulos, K.; Calvo, E.; Pedregal, M.; Hernandez, T.; Rasco, D.; Patnaik, A.; Garcia-Foncillas, J.; Wick, M. Share Save
Phase I/Ib open-label study of an HER2-targeted T cell engager (TCE)-SAR443216 in patients (pts) with advanced solid tumors: Intravenous (IV) dose-escalation results Moreno Garcia, V.; Oh, D-Y.; Ryu, M. H.; Calvo, E.; Garralda, E.; Chung, W-P.; Bai, L-Y.; Rojas Laimito, K. I.; Yildirim, O.; Masciari, S.; Mi, G.; Wang, L.; Kanlikilicer, P.; Buday, B.; Rharbaoui, F.; Abbadessa, G.; Dumbrava, E. E. Share Save
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials Segal, Neil H.; Melero, Ignacio; Moreno, Victor; Steeghs, Neeltje; Marabelle, Aurelien; Rohrberg, Kristoffer; Rodriguez-Ruiz, Maria E.; Eder, Joseph P.; Eng, Cathy; Manji, Gulam A.; Waterkamp, Daniel; Leutgeb, Barbara; Bouseida, Said; Flinn, Nick; Das Thakur, Meghna; Elze, Markus C.; Koeppen, Hartmut; Jamois, Candice; Martin-Facklam, Meret; Lieu, Christopher H.; Calvo, Emiliano; Paz-Ares, Luis; Tabernero, Josep; Argiles, Guillem Share Save
Activity of alpelisib in a panel of breast XPDX models harboring hotspot and uncommon PIK3CA mutations Castaneda, Mercedes; Simonson, Alyssa; Flores, Johnnie; DeBoer, Maci; Lund, Jim; Rouzbahan, Tahmi; Papadopoulos, Kyriakos P.; Lang, Amy; Rodriguez, Gladys; Elmi, Maryam; Rosenthal, Arthur; Rasco, Drew; Moreno, Victor; Patnaik, Amita; Hernandez, Tatiana; Calvo, Emiliano; Smith, Lon; Sharma, Manish; Beeram, Muralidhar; Wick, Michael Share Save
Pharmacokinetics and Safety of Lurbinectedin Administrated with Itraconazole in Cancer Patients: A Drug-Drug Interaction Study Moreno, Irene; Hernandez, Tatiana; Calvo, Emiliano; Fudio, Salvador; Kahatt, Carmen; Martinez, Sara; Iglesias, Jorge Luis; Calafati, Roman Octavio; Perez-Ramos, Laura; Montilla, Lola; Zeaiter, Ali; Lubomirov, Rubin Share Save
Establishment and characterization of a panel of naive and pretreated small cell lung cancer (SCLC) XPDX models Morales, Gabriela Huelgas; Forofontov, Peter; Flores, Johnnie; Simonson, Alyssa; Diaz, Armando, III; Lund, Jim; Banos, Natalia; Papadopoulos, Kyriakos; Rasco, Drew; Patnaik, Amita; Abedi, Ali; Puente, Napoleon; Calvo, Emiliano; Moreno, Victor; Drengler, Ronald; Smith, Lon; Wick, Michael Share Save
Enfortumab vedotin (EV): Efficacy comparison with trastuzumab deruxtecan (T-DXd) and sacituzumab govitecan (SG) and its potential for combination benefit in bladder cancer XPDX models Flores, Johnnie; Sessions, Heaven; Simonson, Alyssa; Banos, Natalia; Rouzbahani, Tahmineh; Diaz, Armando, III; Lund, Jim; Calvo, Emiliano; Moreno, Victor; Papadopoulos, Kyriakos; Rasco, Drew; Patnaik, Amita; Ulmer, Scott; Rodriguez, Luis; Wick, Michael Share Save
Phase I Trial of Viral Vector-Based Personalized Vaccination Elicits Robust Neoantigen-Specific Antitumor T-Cell Responses D'Alise, Anna Morena; Leoni, Guido; Cotugno, Gabriella; Siani, Loredana; Vitale, Rosa; Ruzza, Valentino; Garzia, Irene; Antonucci, Laura; Micarelli, Elisa; Venafra, Veronica; Gogov, Sven; Capone, Alessia; Runswick, Sarah; Martin-Liberal, Juan; Calvo, Emiliano; Moreno, Victor; Symeonides, Stefan N.; Scarselli, Elisa; Bechter, Oliver Share Save
MYC targeting by OMO-103 in solid tumors: a phase 1 trial Garralda, Elena; Beaulieu, Marie-Eve; Moreno, Victor; Casacuberta-Serra, Silvia; Martinez-Martin, Sandra; Foradada, Laia; Alonso, Guzman; Masso-Valles, Daniel; Lopez-Estevez, Sergio; Jauset, Toni; de la Fuente, Elena Corral; Doger, Bernard; Hernandez, Tatiana; Perez-Lopez, Raquel; Arques, Oriol; Cano, Virginia Castillo; Morales, Josefa; Whitfield, Jonathan R.; Niewel, Manuela; Soucek, Laura; Calvo, Emiliano Share Save
Impact of a Moderate CYP3A4 Inducer (Bosentan) on Lurbinectedin Pharmacokinetics and Safety in Patients with Advanced Solid Tumors: An Open-Label, Two-Way, Crossover, Phase Ib Drug-Drug Interaction Study Moreno, Irene; Hernandez, Tatiana; Calvo, Emiliano; Fudio, Salvador; Kahatt, Carmen; Fernandez, Cristian; Iglesias, Jorge Luis; Corral, Gema; Perez-Ramos, Laura; Montilla, Lola; Zeaiter, Ali; Lubomirov, Rubin Share Save
Considerations for the design of antibody drug conjugates (ADCs) for clinical development: lessons learned de Sa, Alfonso Lopez; Diaz-Tejeiro, Cristina; Poyatos-Racionero, Elisa; Nieto-Jimenez, Cristina; Paniagua-Herranz, Lucia; Sanvicente, Adrian; Calvo, Emiliano; Perez-Segura, Pedro; Moreno, Victor; Moris, Francisco; Ocana, Alberto Share Save
Lurbinectedin (LRB) pharmacokinetics (PK) and safety when co-administered with itraconazole (ITZ) in patients with advanced solid tumor Moreno, I.; Hernandez, T.; Calvo, E.; Fudio, S.; Kahatt, C.; Martinez, S.; Iglesias, J.; Calafati, R. O.; Perez Ramos, L.; Montilla, L.; Zeaiter, A.; Lubomirov, R. Share Save
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